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Histone deacetylase 7 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
VorinostatIC5010000.0 [1]
VorinostatKi129.0 [1]
Trichostatin AIC50139.0 [1]
Trichostatin AKi195.0 [1], 300.0 [2]
PanobinostatIC502830.0 [1], 4354.0 [2]
PanobinostatKi2.3 [1], 630.0 [2], 4550.0 [3]
Tubastatin AIC5030000.0 [1]
TubacinIC509700.0 [1], 30000.0 [2]
TubacinKi5426.9 [1], 8500.0 [2]
EntinostatIC5010000.0 [1], 50000.0 [2], 100000.0 [3]
RomidepsinIC5010000.0 [1], 50000.0 [2]
RomidepsinKi1250.0 [1]
DacinostatIC506.11 [1], 2240.0 [2]
DacinostatKi9500.0 [1]
CID 53344908IC5040.0 [1], 40.85 [2], 112.0 [3]
CID 53344908Ki46.3 [1]
BelinostatKi51.0 [1], 75.0 [2]
MocetinostatIC5010000.0 [1]
RicolinostatIC501400.0 [1], 10000.0 [2]
ScriptaidIC502100.0 [1]
ScriptaidKi2250.0 [1]
QuisinostatKi1.7 [1], 66.6 [2]
GivinostatKi240.0 [1]
4-Acetamido-N-(2-amino-5-thiophen-2-ylphenyl)benzamideIC5010000.0 [1], 20000.0 [2]
N-Hydroxy-2,2-diphenylacetamideIC50390.0 [1], 650.0 [2]
CID 24853793IC501.0 [1], 10000.0 [2]
N-(4-Hydroxybiphenyl-3-yl)benzamideIC5050000.0 [1]
N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamideIC5050000.0 [1]
(1r,2r,3r)-2-[4-(5-Fluoranylpyrimidin-2-Yl)phenyl]-N-Oxidanyl-3-Phenyl-Cyclopropane-1-CarboxamideIC50110.0 [1], 120.0 [2]
N-[[4-(Hydroxycarbamoyl)phenyl]methyl]-1-methylpyrrole-2-carboxamideIC504600.0 [1]
Valproic acidIC502000000.0 [1]
Butyric acidIC502000000.0 [1]
4-Phenylbutyric acidIC502000000.0 [1]
N-HydroxybenzamideIC5015600.0 [1]
LargazoleIC5010000.0 [1]
PracinostatKi107.0 [1]
N-Hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamideIC5010.0 [1]
Cudc-101IC50373.0 [1]
FimepinostatIC50426.0 [1]
N-(2-Aminophenyl)benzamideIC5050000.0 [1]
1-(3,4-Dihydroxyphenyl)-2-[(4-hydroxy-6-methylpyrimidin-2-YL)thio]ethanoneIC50100000.0 [1]
Thailandepsin AIC5050000.0 [1]
Nexturastat AIC504460.0 [1]
(E)-5-[4-(Benzenesulfonamido)phenyl]-N-hydroxypent-2-en-4-ynamideKi324.7 [1]
N-Hydroxy-4-[(14-methyl-13,15-dioxo-9,12,14-triazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-9-yl)methyl]benzamideKi442.0 [1]
Azumamide EIC509700.0 [1]
N-Hydroxy-4-phenylbutanamideIC50150000.0 [1]
N-(6-(2-Aminophenylamino)-6-oxohexyl)-4-methylbenzamideIC50180000.0 [1]
9,9,9-Trifluoro-8-Oxo-N-PhenylnonanamideKi4.7 [1]
2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamideIC50100000.0 [1]
2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanoneIC50100000.0 [1]
N-(Quinolin-8-YL)-6-(2-sulfanylacetamido)hexanamideIC502780.0 [1]
N-(4-Aminobiphenyl-3-yl)benzamideIC5050000.0 [1]
4-[2-[2-Hydroxyethyl(Phenyl)amino]-2-Oxidanylidene-Ethyl]-~{n}-Oxidanyl-BenzamideIC5010000.0 [1]
N-(2-Aminophenyl)-N'-phenylheptanediamideIC50180000.0 [1]
N-Hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamideIC5046.0 [1]
HDAC inhibitorIC501293.0 [1]
N-(4-{[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]acetyl}phenyl)acetamideIC5024400.0 [1]
(S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxohexan-2-yl)carbamateIC50785.9 [1]
N-(2-Amino-phenyl)-nicotinamideIC5050000.0 [1]
6-Methyl-2-{[2-oxo-2-(thiophen-2-yl)ethyl]sulfanyl}-3,4-dihydropyrimidin-4-oneIC50100000.0 [1]
N-Hydroxy-5-[[6-oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanamideIC5050000.0 [1]
(E)-N-Hydroxy-3-[4-(4-methoxyphenyl)phenyl]prop-2-enamideIC50213000.0 [1]
1-Methyl-N-[(1S)-1-(5-naphthalen-2-yl-1H-imidazol-2-yl)-7-oxooctyl]piperidine-4-carboxamideIC501.0 [1]
Pimelic Diphenylamide 106IC50100000.0 [1]
6-(1-Adamantylcarbamoylamino)-N-hydroxyhexanamideIC501290.0 [1]
N-HydroxybutanamideIC501000000.0 [1]
N-Hydroxy-5-(4-phenyltriazol-1-yl)pentanamideIC5018700.0 [1]
N-Hydroxy-9H-xanthene-9-carboxamideIC5050.0 [1]
N-[1-[[3-Azido-5-(azidomethyl)phenyl]methyl]pyrazol-4-yl]-N'-hydroxyoctanediamideIC504510.0 [1]
Thailandepsin BIC5027000.0 [1]
3-N-Hydroxy-1-N-(2-phenylethyl)benzene-1,3-dicarboxamideIC5013000.0 [1]
N-Hydroxy-2-propylpentanamideIC5099000.0 [1]
N-[(1S)-1-[5-(2-Methoxyquinolin-3-yl)-1H-imidazol-2-yl]-7-oxononyl]-1-methylazetidine-3-carboxamideIC5010000.0 [1]
N-Hydroxy-4-[(quinolin-8-ylamino)methyl]benzamideIC50709.0 [1]
6-Methyl-2-phenacylsulfanyl-1H-pyrimidin-4-oneIC50100000.0 [1]
2-(4-Chlorophenacylthio)-4-hydroxy-6-methylpyrimidineIC50100000.0 [1]
PandacostatKi1100.0 [1]
(E)-N-Hydroxy-3-[4-(4-hydroxyphenyl)phenyl]prop-2-enamideIC5015600.0 [1]
2-(4-Methoxybenzyloxy)-N8-hydroxy-N1-phenyloctanediamideIC50432.0 [1]
(2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5-phenyl-2,4-pentadienamideIC504.4 [1]
(2E,4E)-N-Hydroxy-5-[4-(4-methoxyphenyl)phenyl]penta-2,4-dienamideIC50100000.0 [1]
N-(2-Amino-5-thiophen-2-ylphenyl)benzamideIC5050000.0 [1]
N-(4-Aminobiphenyl-3-yl)nicotinamideIC5050000.0 [1]
N-(2-Amino-5-(thiophen-2-yl)phenyl)nicotinamideIC5050000.0 [1]
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamideKi7000.0 [1]
1-[5-[3-[4-(1,3,4-Oxadiazole-2-yl)phenoxymethyl]-1,2,4-oxadiazole-5-yl]-2-thienyl]trifluoroethanoneIC5070.0 [1]
(3S,6S,9S,13S)-9-Methyl-13-(2-methylpropyl)-3-(naphthalen-1-ylmethyl)-6-(6-oxooctyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetroneIC5010000.0 [1]
5-[4-[[3-Azido-5-(azidomethyl)benzoyl]amino]phenyl]-N-[7-(hydroxyamino)-7-oxoheptyl]-1,2-oxazole-3-carboxamideIC502230.0 [1]
(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]prop-2-enamideIC50100000.0 [1]
2-((3-Phenethoxyphenyl)Amino)BenzamideIC5030000.0 [1]
N-(3,4-Dimethylphenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamideKi2500.0 [1]
(1r,2r,3r)-2-[4-(1,3-Oxazol-5-Yl)phenyl]-N-Oxidanyl-3-Phenyl-Cyclopropane-1-CarboxamideIC5030.0 [1]
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]propanoic acidIC5050000.0 [1]
(2R)-2-[(1-Hydroxy-6-sulfanylidenepyridine-2-carbonyl)amino]-2-phenylacetic acidIC5049000.0 [1]
(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamideIC5030800.0 [1]
N-Hydroxy-2-[[5-(3-nitrophenyl)furan-2-yl]methyl]-3,4-dihydro-1H-isoquinoline-7-carboxamideIC5060700.0 [1]
N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamideIC50100000.0 [1]
(2S)-N'-Hydroxy-2-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)acetyl]amino]-N-[2-(2-phenyl-1H-indol-3-yl)ethyl]octanediamideIC504200.0 [1]
2-(4-(4-(4-Fluorophenyl)-1-hydroxybut-3-en-2-yl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamideIC50102.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Histone deacetylase 7 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/histone-deacetylase-7-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Histone deacetylase 7 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-deacetylase-7-inhibitors-ic50-ki.
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