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Histone deacetylase 3/NCoR1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
9,9,9-Trifluoro-8-Oxo-N-PhenylnonanamideIC503.0 [1], 11.0 [2], 18.0 [3], 52.0 [4]
9,9,9-Trifluoro-8-Oxo-N-PhenylnonanamideKi11.0 [1], 570.0 [2]
VorinostatIC509.8 [1], 51.0 [2]
VorinostatKi9.9 [1], 12.0 [2]
Trichostatin AKi0.54 [1]
RomidepsinKi0.15 [1]
MocetinostatIC5022.0 [1]
Azumamide EKi25.0 [1]
Azumamide AKi3200.0 [1]
Azumamide BKi3000.0 [1]
Azumamide DKi3700.0 [1]
Azumamide CKi14.0 [1]
N-(2-Aminophenyl)-5-[1-[2-(3-nitrophenyl)ethyl]triazol-4-yl]thiophene-2-carboxamideIC50260.0 [1]
Tert-butyl 2-[[4-[(2-aminophenyl)carbamoyl]phenyl]methylimino]-5-(1H-indol-3-ylmethyl)-4-oxoimidazolidine-1-carboxylateIC5040.0 [1]
N-(2-Aminophenyl)-4-[[(4-benzyl-5-oxoimidazolidin-2-ylidene)amino]methyl]benzamideIC5030.0 [1]
N-(2-Aminophenyl)-4-[[[(4S)-4-phenyl-1,3-thiazolidin-2-ylidene]amino]methyl]benzamideIC5012.0 [1]
N-(2-Aminophenyl)-4-[[[(4S)-4-(4-hydroxyphenyl)-1,3-thiazolidin-2-ylidene]amino]methyl]benzamideIC5016.0 [1]
N-(2-Aminophenyl)-4-[[(4-oxo-5-phenylimidazolidin-2-ylidene)amino]methyl]benzamideIC5014.0 [1]
4-[[(1-Acetyl-5-benzyl-4-oxoimidazolidin-2-ylidene)amino]methyl]-N-(2-aminophenyl)benzamideIC5083.0 [1]
4-[[[1-Acetyl-5-(1H-indol-3-ylmethyl)-4-oxoimidazolidin-2-ylidene]amino]methyl]-N-(2-aminophenyl)benzamideIC5070.0 [1]
N-(2-Aminophenyl)-4-[[[4-(1H-indol-3-ylmethyl)-5-oxoimidazolidin-2-ylidene]amino]methyl]benzamideIC50104.0 [1]
N-(2-Aminophenyl)-4-[[[(4R)-4-phenyl-1,3-thiazolidin-2-ylidene]amino]methyl]benzamideIC5079.0 [1]
N-(2-Aminophenyl)-4-[[[(4S)-4-benzyl-1,3-thiazolidin-2-ylidene]amino]methyl]benzamideIC5052.0 [1]
N-(2-Aminophenyl)-4-[[[(4R)-4-benzyl-1,3-thiazolidin-2-ylidene]amino]methyl]benzamideIC5036.0 [1]
N-(2-Aminophenyl)-4-[[[(4R,5R)-4,5-diphenyl-1,3-thiazolidin-2-ylidene]amino]methyl]benzamideIC50287.0 [1]
N-(2-Aminophenyl)-4-[[[(4S,5S)-4,5-diphenyl-1,3-thiazolidin-2-ylidene]amino]methyl]benzamideIC50388.0 [1]
Nampt-IN-3IC501867.0 [1]
2-[[7-(Hydroxyamino)-7-oxoheptyl]-(3-methylbutyl)amino]-N-(3-imidazol-1-ylpropyl)-1,3-thiazole-5-carboxamideIC500.67 [1]
N-(2-Aminophenyl)-4-[4-[bis(2-chloroethyl)amino]phenyl]butanamideIC509520.0 [1]
N-Hydroxy-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamideIC5045.0 [1]
N-[8-(Hydroxyamino)-8-oxooctyl]-1-[4-[[4-[4-(methanesulfonamido)phenyl]pyrimidin-2-yl]amino]phenyl]piperidine-4-carboxamideIC5017.0 [1]
2-[(4-Fluorophenyl)methyl-[7-(hydroxyamino)-7-oxoheptyl]amino]-N-(3-imidazol-1-ylpropyl)-1,3-thiazole-5-carboxamideIC504.1 [1]
N-[4-[(E)-3-(Hydroxyamino)-3-oxoprop-1-enyl]phenyl]-1-[4-[[4-[4-(methanesulfonamido)phenyl]pyrimidin-2-yl]amino]phenyl]piperidine-4-carboxamideIC50234.0 [1]
N-(2-Aminophenyl)-4-[[[(5R)-5-phenyl-4,5-dihydro-1,3-thiazol-2-yl]amino]methyl]benzamideIC5023.0 [1]
N-(2-Aminophenyl)-4-[[[(5S)-5-phenyl-4,5-dihydro-1,3-thiazol-2-yl]amino]methyl]benzamideIC5012.0 [1]
N-(2-Aminophenyl)-4-[[(4S)-4-benzyl-4,5-dihydro-1,3-thiazol-2-yl]sulfanylmethyl]benzamideIC50509.0 [1]
N-(2-Aminophenyl)-4-[[(4S)-4-(1H-indol-3-ylmethyl)-4,5-dihydro-1,3-thiazol-2-yl]sulfanylmethyl]benzamideIC50890.0 [1]
N-(2-Aminophenyl)-4-[[(4S)-4-phenyl-4,5-dihydro-1,3-thiazol-2-yl]sulfanylmethyl]benzamideIC5063.0 [1]
3-Amino-4-[[4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzoyl]amino]benzoic acidIC5020000.0 [1]
N-(3-Aminonaphthalen-2-yl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC50630.0 [1]
N-(2-Amino-4-bromophenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC504720.0 [1]
N-(2-Amino-4-hydroxyphenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC50719.0 [1]
N-[2-Amino-4-[[tert-butyl(dimethyl)silyl]oxymethyl]phenyl]-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC5020000.0 [1]
N-[2-Amino-4-(hydroxymethyl)phenyl]-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC5020000.0 [1]
Benzyl 3-amino-4-[[4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzoyl]amino]benzoateIC5020000.0 [1]
N-(2-Amino-4-phenylphenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC5020000.0 [1]
N-(2-Amino-4-methoxyphenyl)-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC50111.0 [1]
N-Hydroxy-4-[[(4-pyridin-3-ylpyrimidin-2-yl)amino]methyl]benzamideIC5031.0 [1]
Items per page: 1 - 10 of 48
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References

This online tool may be cited as follows

MLA

"Quest Database™ Histone deacetylase 3/NCoR1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/histone-deacetylase-3-ncor1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Histone deacetylase 3/NCoR1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-deacetylase-3-ncor1-inhibitors-ic50-ki.
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