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Histone deacetylase 11 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
VorinostatIC50362.0 [1]
VorinostatKi13.0 [1], 31.0 [2], 36.0 [3], 60.0 [4]
Trichostatin AIC5015.2 [1]
Trichostatin AKi401.0 [1]
Tubastatin AIC5030000.0 [1]
TubacinIC503790.0 [1], 30000.0 [2]
TubacinKi718.7 [1]
PanobinostatIC504112.0 [1]
PanobinostatKi3.5 [1], 1200.0 [2]
EntinostatIC50900.0 [1], 1300.0 [2]
RomidepsinIC500.3 [1], 10000.0 [2]
MocetinostatIC50590.0 [1]
RicolinostatIC5010000.0 [1]
QuisinostatKi0.07 [1], 1300.0 [2]
Azumamide CKi35.0 [1], 60.0 [2]
(E)-N-Hydroxy-3-[2-(2-phenylethyl)-1-(2-pyrrolidin-1-ylethyl)benzimidazol-5-yl]prop-2-enamideKi12.8 [1], 13.0 [2]
(2S)-N'-Hydroxy-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]-N-phenyloctanediamideIC5013.0 [1], 37.0 [2]
(2R)-5-Oxo-N-[(2S)-1-oxo-7-sulfanyl-1-[3-(trifluoromethyl)anilino]heptan-2-yl]pyrrolidine-2-carboxamideIC5044.0 [1]
N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamideIC5050000.0 [1]
(2S)-N'-Hydroxy-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]-N-[3-(trifluoromethyl)phenyl]octanediamideIC5055.0 [1], 55.5 [2]
(2S)-N'-Hydroxy-2-[[(2S)-4-oxoazetidine-2-carbonyl]amino]-N-phenyloctanediamideIC5037.0 [1], 135.0 [2]
(2S)-N'-Hydroxy-N-(3-methylphenyl)-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]octanediamideIC5015.0 [1], 15.5 [2]
Chembl4126661IC503.0 [1], 15.0 [2]
Chembl4127894IC505.0 [1], 85.0 [2]
Chembl4129930IC5010000.0 [1], 25000.0 [2]
Chembl4127735IC503.0 [1], 12.0 [2]
Chembl4129134IC506.0 [1], 130.0 [2]
Chembl4126502IC5027.0 [1], 270.0 [2]
Chembl4128972IC502.0 [1], 20.0 [2]
BelinostatKi27.0 [1]
DacinostatIC505.58 [1]
LargazoleIC5010000.0 [1]
PracinostatKi43.0 [1]
FimepinostatIC505.4 [1]
N-(2-Aminophenyl)benzamideIC5050000.0 [1]
Nexturastat AIC505140.0 [1]
CID 71520717IC50852.0 [1]
N-Hydroxy-4-[(14-methyl-13,15-dioxo-9,12,14-triazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-9-yl)methyl]benzamideKi495.0 [1]
Azumamide EKi60.0 [1]
7-Mercapto-heptanoic acid phenylamideIC50262.0 [1]
8-Mercapto-octanoic acid phenylamideIC50133.0 [1]
Tert-butyl N-[(2S)-1-(cyclopentylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamateIC5030700.0 [1]
N-(Quinolin-8-YL)-6-(2-sulfanylacetamido)hexanamideIC50610.0 [1]
N-(4-Aminobiphenyl-3-yl)benzamideIC5050000.0 [1]
4-[2-[2-Hydroxyethyl(Phenyl)amino]-2-Oxidanylidene-Ethyl]-~{n}-Oxidanyl-BenzamideIC5010000.0 [1]
N-Hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamideIC502.1 [1]
Epicoccolide BIC5012900.0 [1]
6-Mercapto-hexanoic acid phenylamideIC50659.0 [1]
7-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]-N-hydroxyheptanamideIC50930.0 [1]
Largazole ThiolIC503.0 [1]
(1S,9R)-5,6,12,13,14-Pentahydroxy-4,11-dimethyl-16-oxo-8,17-dioxatetracyclo[7.7.1.02,7.010,15]heptadeca-2(7),3,5,10,12,14-hexaene-3-carbaldehydeIC5011700.0 [1]
N-(2-Amino-phenyl)-nicotinamideIC5050000.0 [1]
N-Hydroxy-5-[[6-oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanamideIC50100.0 [1]
(E)-N-Hydroxy-3-[4-(4-methoxyphenyl)phenyl]prop-2-enamideIC5073000.0 [1]
Azumamide AKi5000.0 [1]
Azumamide BKi5000.0 [1]
Azumamide DKi5000.0 [1]
6-(1-Adamantylcarbamoylamino)-N-hydroxyhexanamideIC50190.0 [1]
N-(4-Hydroxybiphenyl-3-yl)benzamideIC5050000.0 [1]
N-[1-[[3-Azido-5-(azidomethyl)phenyl]methyl]pyrazol-4-yl]-N'-hydroxyoctanediamideIC50476.0 [1]
Hdac8-IN-1IC5020000.0 [1]
Benzamide, N-(((6-(hydroxyamino)-6-oxohexyl)amino)carbonyl)-Ki39.0 [1]
N-Hydroxy-4-[(quinolin-8-ylamino)methyl]benzamideIC50376.0 [1]
4-N-Hydroxy-1-N-[(2S)-3-(1H-indol-3-yl)-1-(4-methylanilino)-1-oxopropan-2-yl]benzene-1,4-dicarboxamideIC503500.0 [1]
(E)-N-Hydroxy-3-[4-(4-hydroxyphenyl)phenyl]prop-2-enamideIC505010.0 [1]
2-(4-Methoxybenzyloxy)-N8-hydroxy-N1-phenyloctanediamideIC50197.0 [1]
N'-Hydroxy-N-(2-phenylethyl)octanediamideIC501130.0 [1]
(2E,4E)-N-Hydroxy-5-[4-(4-methoxyphenyl)phenyl]penta-2,4-dienamideIC50100000.0 [1]
N-(2-Amino-5-thiophen-2-ylphenyl)benzamideIC5050000.0 [1]
N-(4-Aminobiphenyl-3-yl)nicotinamideIC5050000.0 [1]
N-(2-Amino-5-(thiophen-2-yl)phenyl)nicotinamideIC5050000.0 [1]
(E)-3-[1-[3-(Dimethylamino)-2,2-dimethylpropyl]-2-(2-phenylethyl)benzimidazol-5-yl]-N-hydroxyprop-2-enamideKi16.0 [1]
(3S,6S,9S,13S)-9-Methyl-13-(2-methylpropyl)-3-(naphthalen-1-ylmethyl)-6-(6-oxooctyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetroneIC50300.0 [1]
N'-Hydroxy-N-[3-(trifluoromethyl)phenyl]octanediamideIC5075.1 [1]
5-[4-[[3-Azido-5-(azidomethyl)benzoyl]amino]phenyl]-N-[7-(hydroxyamino)-7-oxoheptyl]-1,2-oxazole-3-carboxamideIC50116.0 [1]
(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]prop-2-enamideIC505530.0 [1]
2-((3-Phenethoxyphenyl)Amino)BenzamideIC5030000.0 [1]
(E)-N-Hydroxy-3-[2-(2-phenylethyl)-1-(2-piperidin-1-ylethyl)benzimidazol-5-yl]prop-2-enamideKi14.0 [1]
N-[6-(Hydroxyamino)-6-oxohexoxy]-3-methylbenzamideIC502135.0 [1]
N-[6-(Hydroxyamino)-6-oxohexoxy]-3,4-dimethylbenzamideIC50997.0 [1]
4-Chloro-N-[(2S)-1-[4-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]phenoxy]-3-(1H-indol-3-yl)propan-2-yl]benzamideIC50900.4 [1]
(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamideIC50100000.0 [1]
N-Hydroxy-2-[[5-(3-nitrophenyl)furan-2-yl]methyl]-3,4-dihydro-1H-isoquinoline-7-carboxamideIC5075300.0 [1]
(Z)-6-[(2R,5R,8R,11R)-8-Benzyl-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-4-enoic acidKi1500.0 [1]
(2S)-N-[(2S)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-5-oxopyrrolidine-2-carboxamideIC5030.0 [1]
(2R)-N-[(2S)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-6-oxopiperidine-2-carboxamideIC5010.0 [1]
(2R)-N-[(2R)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-5-oxopyrrolidine-2-carboxamideIC50102.0 [1]
N-Hydroxy-4-[2-[(E)-2-phenylethenyl]-1,3-thiazol-4-yl]butanamideIC5032820.0 [1]
2-(4-(4-(4-Fluorophenyl)-1-hydroxybut-3-en-2-yl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamideIC5020.7 [1]
4-[(1,1-Dioxo-2,3-dihydrothieno[3,2-b]indol-4-yl)methyl]-N-hydroxybenzamideIC5017000.0 [1]
3-[(2E,4E)-5-(3,4-Dimethoxyphenyl)penta-2,4-dienoyl]-7-methoxychromen-2-oneIC5074000.0 [1]
(5R,8S,11S)-5-Methyl-11-[(E)-4-[[(E)-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl]disulfanyl]but-1-enyl]-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trioneIC500.1 [1]
Tert-butyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[[(E)-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl]disulfanyl]propanoateIC500.2 [1]
N-Hydroxy-5-[1-[(4-indol-1-ylphenyl)methyl]pyrazol-3-yl]pentanamideIC50897.0 [1]
N-Hydroxy-5-[1-[(4-phenylphenyl)methyl]pyrazol-3-yl]pentanamideIC501725.0 [1]
(E)-6-[(2R,5R,8R,11S)-8-Benzyl-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-5-enoic acidKi3200.0 [1]
(E)-6-[(2R,5R,8R,11S)-8-[(4-Hydroxyphenyl)methyl]-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-5-enoic acidKi1300.0 [1]
(E)-6-[(2R,5R,8R,11S)-8-(1H-Indol-3-ylmethyl)-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-5-enoic acidKi1100.0 [1]
6-[(2R,5R,8R,11R)-8-Benzyl-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hexanoic acidKi2000.0 [1]
6-[(2R,5R,8R,11R)-8-[(4-Hydroxyphenyl)methyl]-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hexanoic acidKi1000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Histone deacetylase 11 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/histone-deacetylase-11-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Histone deacetylase 11 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-deacetylase-11-inhibitors-ic50-ki.
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