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Histone deacetylase 10 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
VorinostatIC50430.0 [1]
VorinostatKi40.0 [1], 50.0 [2], 60.0 [3]
Trichostatin AIC5020.1 [1]
Trichostatin AKi4.76 [1], 7.0 [2]
Tubastatin AIC5030000.0 [1]
TubacinIC503710.0 [1], 30000.0 [2]
TubacinKi373.7 [1]
PanobinostatIC504.0 [1], 4.45 [2]
PanobinostatKi5.1 [1], 31.0 [2]
EntinostatIC5011100.0 [1], 50100.0 [2]
RomidepsinIC500.9 [1], 11.0 [2]
RicolinostatIC50194.0 [1], 10000.0 [2]
AbexinostatKi20.0 [1], 24.0 [2]
QuisinostatKi0.05 [1], 4.4 [2]
N-Hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamideIC5013000.0 [1]
FimepinostatIC502.8 [1]
N-Hydroxy-4-[(14-methyl-13,15-dioxo-9,12,14-triazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-9-yl)methyl]benzamideIC5010500.0 [1]
N-Hydroxy-4-[(14-methyl-13,15-dioxo-9,12,14-triazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-9-yl)methyl]benzamideKi452.0 [1]
N-(Quinolin-8-YL)-6-(2-sulfanylacetamido)hexanamideIC5010650.0 [1], 10700.0 [2]
N'-Hydroxy-N-[3-(1-phenyltriazol-4-yl)phenyl]octanediamideIC5027.7 [1]
Azumamide CKi10.0 [1], 20.0 [2]
6-(1-Adamantylcarbamoylamino)-N-hydroxyhexanamideIC50173.0 [1], 270.0 [2]
(E)-N-Hydroxy-3-[2-(2-phenylethyl)-1-(2-pyrrolidin-1-ylethyl)benzimidazol-5-yl]prop-2-enamideKi18.9 [1], 19.0 [2]
(2S)-N'-Hydroxy-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]-N-phenyloctanediamideIC50113.0 [1], 125.0 [2]
(2R)-5-Oxo-N-[(2S)-1-oxo-7-sulfanyl-1-[3-(trifluoromethyl)anilino]heptan-2-yl]pyrrolidine-2-carboxamideIC507.0 [1]
N-Hydroxy-2-(1-methylpyrrole-2-carbonyl)-3,4-dihydro-1H-isoquinoline-6-carboxamideIC5050000.0 [1]
(2S)-N'-Hydroxy-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]-N-[3-(trifluoromethyl)phenyl]octanediamideIC5010.6 [1], 11.0 [2]
(2S)-N'-Hydroxy-2-[[(2S)-4-oxoazetidine-2-carbonyl]amino]-N-phenyloctanediamideIC50113.0 [1], 125.0 [2]
(2S)-N'-Hydroxy-N-(3-methylphenyl)-2-[[(2R)-5-oxopyrrolidine-2-carbonyl]amino]octanediamideIC5030.0 [1], 30.3 [2]
N-[[4-(Hydroxycarbamoyl)phenyl]methyl]-1-methylpyrrole-2-carboxamideIC503700.0 [1]
BendamustineIC5072.0 [1]
BelinostatKi59.0 [1]
ScriptaidIC50300.0 [1]
DacinostatIC508.41 [1]
LargazoleIC502210.0 [1]
PracinostatKi23.0 [1]
Cudc-101IC5026.1 [1]
HDAC6 InhibitorIC5090.7 [1]
Nexturastat AIC507570.0 [1]
Azumamide EKi20.0 [1]
4-Dimethylamino-N-[5-(2-mercaptoacetylamino)pentyl]benzamideIC501540.0 [1]
7-Mercapto-heptanoic acid phenylamideIC50270.0 [1]
8-Mercapto-octanoic acid phenylamideIC50252.0 [1]
Tert-butyl N-[(2S)-1-(cyclopentylamino)-1-oxo-7-sulfanylheptan-2-yl]carbamateIC505210.0 [1]
4-[2-[2-Hydroxyethyl(Phenyl)amino]-2-Oxidanylidene-Ethyl]-~{n}-Oxidanyl-BenzamideIC503000.0 [1]
N-Hydroxy-2-(4-(naphthalen-2-ylsulfonyl)piperazin-1-yl)pyrimidine-5-carboxamideIC504.3 [1]
Epicoccolide BIC508100.0 [1]
6-Mercapto-hexanoic acid phenylamideIC501220.0 [1]
7-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]-N-hydroxyheptanamideIC5080.0 [1]
Largazole ThiolIC500.5 [1]
(1S,9R)-5,6,12,13,14-Pentahydroxy-4,11-dimethyl-16-oxo-8,17-dioxatetracyclo[7.7.1.02,7.010,15]heptadeca-2(7),3,5,10,12,14-hexaene-3-carbaldehydeIC508400.0 [1]
4-Dimethylamino-N-[6-(2-mercaptoacetylamino)hexyl]benzamideIC503430.0 [1]
N-Hydroxy-5-[[6-oxo-4-(4-phenylphenyl)-1H-pyrimidin-2-yl]sulfanyl]pentanamideIC5040.0 [1]
(E)-N-Hydroxy-3-[4-(4-methoxyphenyl)phenyl]prop-2-enamideIC5091000.0 [1]
Pimelic Diphenylamide 106IC5066200.0 [1]
N-{6-[(Phenylcarbamoyl)amino]hexyl}-2-sulfanylacetamideIC5030000.0 [1]
N-[1-[[3-Azido-5-(azidomethyl)phenyl]methyl]pyrazol-4-yl]-N'-hydroxyoctanediamideIC50140.0 [1]
Hdac8-IN-1IC5020000.0 [1]
(E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-acrylamideIC50280.0 [1]
Benzamide, N-(((6-(hydroxyamino)-6-oxohexyl)amino)carbonyl)-Ki40.0 [1]
1-(4-(Dimethylamino)phenyl)-3-(7-(hydroxyamino)-7-oxoheptyl)ureaIC50176.0 [1]
(E)-3-(5-Benzoyl-1-methyl-1H-pyrrol-3-yl)-N-hydroxy-acrylamideIC5050.0 [1]
N-Hydroxy-4-[(quinolin-8-ylamino)methyl]benzamideIC509791.0 [1]
N-Hydroxy-7-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]octanamideIC5031.0 [1]
(E)-N-Hydroxy-3-[4-(4-hydroxyphenyl)phenyl]prop-2-enamideIC5011000.0 [1]
N-[4-[2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]phenyl]phenyl]-N'-hydroxyoctanediamideIC5046.1 [1]
4-(Dimethylamino)-N-[4-(2-sulfanylacetamido)butyl]benzamideIC5029700.0 [1]
4-(Dimethylamino)-N-[3-(2-sulfanylacetamido)propyl]benzamideIC508780.0 [1]
2-(4-Methoxybenzyloxy)-N8-hydroxy-N1-phenyloctanediamideIC50179.0 [1]
(5R,8S,11S)-5-Methyl-8-propan-2-yl-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trioneIC500.5 [1]
5-(3-Aminophenyl)-N-(7-(hydroxyamino)-7-oxoheptyl)isoxazole-3-carboxamideIC5017.5 [1]
N'-Hydroxy-N-(2-phenylethyl)octanediamideIC501350.0 [1]
(2E,4E)-N-Hydroxy-5-[4-(4-methoxyphenyl)phenyl]penta-2,4-dienamideIC50100000.0 [1]
5-(5-(4-(3-Aminophenyl)thiazol-2-ylamino)-5-oxopentyl)-N-hydroxyisoxazole-3-carboxamideIC50250.0 [1]
(E)-3-[1-[3-(Dimethylamino)-2,2-dimethylpropyl]-2-(2-phenylethyl)benzimidazol-5-yl]-N-hydroxyprop-2-enamideKi23.0 [1]
(3S,6S,9S,13S)-9-Methyl-13-(2-methylpropyl)-3-(naphthalen-1-ylmethyl)-6-(6-oxooctyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetroneIC50150.0 [1]
N'-(2-Aminophenyl)-N-[3-(1-phenyltriazol-4-yl)phenyl]octanediamideIC5030000.0 [1]
N'-Hydroxy-N-[3-(trifluoromethyl)phenyl]octanediamideIC50374.0 [1]
5-[4-[[3-Azido-5-(azidomethyl)benzoyl]amino]phenyl]-N-[7-(hydroxyamino)-7-oxoheptyl]-1,2-oxazole-3-carboxamideIC50776.0 [1]
(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]prop-2-enamideIC506320.0 [1]
2-((3-Phenethoxyphenyl)Amino)BenzamideIC5030000.0 [1]
(E)-N-Hydroxy-3-[2-(2-phenylethyl)-1-(2-piperidin-1-ylethyl)benzimidazol-5-yl]prop-2-enamideKi23.0 [1]
(7R)-N-Hydroxy-7-[(4-pyridin-3-ylpyrimidin-2-yl)amino]-5,6,7,8-tetrahydronaphthalene-2-carboxamideIC50100000.0 [1]
N-Hydroxy-2-[[5-(3-nitrophenyl)furan-2-yl]methyl]-3,4-dihydro-1H-isoquinoline-7-carboxamideIC5071100.0 [1]
(Z)-6-[(2R,5R,8R,11R)-8-Benzyl-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-4-enoic acidKi700.0 [1]
(2S)-N-[(2S)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-5-oxopyrrolidine-2-carboxamideIC5015.0 [1]
(2R)-N-[(2S)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-6-oxopiperidine-2-carboxamideIC5032.0 [1]
(2R)-N-[(2R)-1-Anilino-1-oxo-7-sulfanylheptan-2-yl]-5-oxopyrrolidine-2-carboxamideIC5040.0 [1]
N-Hydroxy-4-[2-[(E)-2-phenylethenyl]-1,3-thiazol-4-yl]butanamideIC5078310.0 [1]
2-(4-(4-(4-Fluorophenyl)-1-hydroxybut-3-en-2-yl)piperazin-1-yl)-N-hydroxypyrimidine-5-carboxamideIC5042.6 [1]
4-[(1,1-Dioxo-2,3-dihydrothieno[3,2-b]indol-4-yl)methyl]-N-hydroxybenzamideIC5013000.0 [1]
3-[(2E,4E)-5-(3,4-Dimethoxyphenyl)penta-2,4-dienoyl]-7-methoxychromen-2-oneIC5085000.0 [1]
(5R,8S,11S)-5-Methyl-11-[(E)-4-[[(E)-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl]disulfanyl]but-1-enyl]-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-triene-6,9,13-trioneIC500.2 [1]
Tert-butyl (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[[(E)-4-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-8-propan-2-yl-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-11-yl]but-3-enyl]disulfanyl]propanoateIC500.5 [1]
N-Hydroxy-5-(1-phenylpyrazol-3-yl)pentanamideIC50774.0 [1]
N-Hydroxy-5-[1-[(4-indol-1-ylphenyl)methyl]pyrazol-3-yl]pentanamideIC50136.0 [1]
5-[1-[(4-Anilinophenyl)methyl]pyrazol-3-yl]-N-hydroxypentanamideIC5025.0 [1]
N-Hydroxy-5-[1-[(4-phenylphenyl)methyl]pyrazol-3-yl]pentanamideIC5029.0 [1]
(E)-6-[(2R,5R,8R,11S)-8-Benzyl-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-5-enoic acidKi1600.0 [1]
(E)-6-[(2R,5R,8R,11S)-8-[(4-Hydroxyphenyl)methyl]-5-methyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-5-enoic acidKi700.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Histone deacetylase 10 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/histone-deacetylase-10-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Histone deacetylase 10 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-deacetylase-10-inhibitors-ic50-ki.
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