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Histone deacetylase 1/3/5/8 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
VorinostatIC50110.0 [1], 120.0 [2], 140.0 [3]
UbenimexIC50100000.0 [1], 1000000.0 [2]
2-(5'-Bromo-2'-oxospiro[1,3-dioxolane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
(2S)-N-Hydroxy-4-methyl-2-(phenylcarbamoylamino)pentanamideIC50100000.0 [1]
2-[[2-(5'-Bromo-2'-oxospiro[1,3-dioxolane-2,3'-indole]-1'-yl)acetyl]amino]-N-hydroxyacetamideIC50330.0 [1]
(2S)-2-[(2-Fluorophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(2-Chlorophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(2-Bromophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-4-methyl-2-[(2-methylphenyl)carbamoylamino]pentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-2-[(2-methoxyphenyl)carbamoylamino]-4-methylpentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-4-methyl-2-[[2-(trifluoromethyl)phenyl]carbamoylamino]pentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-2-[(2-hydroxyphenyl)carbamoylamino]-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(3-Fluorophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(3-Chlorophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(3-Bromophenyl)carbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-4-methyl-2-[(3-methylphenyl)carbamoylamino]pentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-2-[(3-methoxyphenyl)carbamoylamino]-4-methylpentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-4-methyl-2-[[3-(trifluoromethyl)phenyl]carbamoylamino]pentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-2-[(3-hydroxyphenyl)carbamoylamino]-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(2-Fluorophenyl)methylcarbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(2-Chlorophenyl)methylcarbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-2-[(2-Bromophenyl)methylcarbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-4-methyl-2-[(2-methylphenyl)methylcarbamoylamino]pentanamideIC50100000.0 [1]
(2S)-2-[(3-Chlorophenyl)methylcarbamoylamino]-N-hydroxy-4-methylpentanamideIC50100000.0 [1]
(2S)-N-Hydroxy-4-methyl-2-[(3-methylphenyl)methylcarbamoylamino]pentanamideIC50100000.0 [1]
2-(5'-Chloro-2'-oxospiro[1,3-dioxepane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
2-(5'-Fluoro-2'-oxospiro[1,3-dioxepane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
2-(5'-Chloro-2'-oxospiro[1,3-dioxolane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
2-(5'-Fluoro-2'-oxospiro[1,3-dioxolane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
2-(5'-Chloro-2'-oxospiro[1,3-dioxane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
2-(5'-Fluoro-2'-oxospiro[1,3-dioxane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
2-(5'-Bromo-2'-oxospiro[1,3-dioxane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
(4R)-3-Oxo-4-(tert-butyloxycarbonylamino)-5-phenylpentanoic acid methyl esterIC501000000.0 [1]
Benzyl (4R)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-5-phenylpentanoateIC501000000.0 [1]
Methyl (2S)-4-methyl-2-[[(4R)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-5-phenylpentanoyl]amino]pentanoateIC501000000.0 [1]
Methyl (2S)-2-[[(4R)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-5-phenylpentanoyl]amino]-3-phenylpropanoateIC501000000.0 [1]
Methyl (2S)-2-[[(4R)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxo-5-phenylpentanoyl]amino]-2-phenylacetateIC501000000.0 [1]
Methyl (4R)-4-amino-3-oxo-5-phenylpentanoateIC501000000.0 [1]
Benzyl (4R)-4-amino-3-oxo-5-phenylpentanoateIC501000000.0 [1]
Methyl (2S)-2-[[(4R)-4-amino-3-oxo-5-phenylpentanoyl]amino]-4-methylpentanoateIC501000000.0 [1]
Methyl (2S)-2-[[(4R)-4-amino-3-oxo-5-phenylpentanoyl]amino]-3-phenylpropanoateIC501000000.0 [1]
Methyl (2S)-2-[[(4R)-4-amino-3-oxo-5-phenylpentanoyl]amino]-2-phenylacetateIC501000000.0 [1]
(2S)-2-[[(4R)-4-Amino-3-oxo-5-phenylpentanoyl]amino]-4-methylpentanoic acidIC501000000.0 [1]
(2S)-2-[[(4R)-4-Amino-3-oxo-5-phenylpentanoyl]amino]-3-phenylpropanoic acidIC501000000.0 [1]
(2S)-2-[[(4R)-4-Amino-3-oxo-5-phenylpentanoyl]amino]-2-phenylacetic acidIC501000000.0 [1]
2-(5'-Bromo-2'-oxospiro[1,3-dioxepane-2,3'-indole]-1'-yl)-N-hydroxyacetamideIC50100000.0 [1]
Items per page: 1 - 10 of 46
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References

This online tool may be cited as follows

MLA

"Quest Database™ Histone deacetylase 1/3/5/8 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/histone-deacetylase-1-3-5-8-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Histone deacetylase 1/3/5/8 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/histone-deacetylase-1-3-5-8-inhibitors-ic50-ki.
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