 | 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine | IC50 | 86.0 [1] |
| 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine | Ki | 46.0 [1] |
 | Thioperamide | IC50 | 667.0 [1], 680.0 [2], 977.0 [3] |
 | Histamine | Ki | 14.45 [1] |
 | (5-Chloro-1H-benzimidazol-2-yl)(4-methylpiperazin-1-yl)methanone | IC50 | 138.0 [1], 530.0 [2] |
| (5-Chloro-1H-benzimidazol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 39.6 [1] |
 | Adriforant | IC50 | 0.65 [1], 1.3 [2], 4.9 [3], 30.0 [4] |
 | Immepip | Ki | 4.57e+16 [1] |
 | Imetit | Ki | 1.6 [1], 3.6 [2], 6.31 [3] |
 | 4-(1H-Imidazol-5-yl)butan-1-amine | Ki | 10.0 [1], 12.7 [2], 14.45 [3], 6.92e+16 [4] |
 | (5-Amino-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 15.0 [1], 25.12 [2], 31.62 [3], 14996848.36 [4] |
 | (R)-alpha-Methylhistamine | Ki | 146.0 [1], 184.0 [2], 251.19 [3], 4168690000000000.0 [4] |
 | Jnj-39758979 | Ki | 12.0 [1], 12.5 [2], 10000.0 [3] |
 | (5-Fluoro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 15.0 [1], 15.85 [2], 14996848.36 [3] |
 | 2-Chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine | Ki | 6.0 [1], 25.12 [2], 28.18 [3], 102.33 [4] |
 | 6-Chloro-2-(4-methylpiperazin-1-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine | IC50 | 69.18 [1] |
| 6-Chloro-2-(4-methylpiperazin-1-yl)-N-(thiophen-2-ylmethyl)quinazolin-4-amine | Ki | 7.59 [1], 42.66 [2] |
 | (5-Hydroxy-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone | Ki | 23.0 [1], 25.12 [2], 23014418.17 [3] |
 | (7-Amino-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone | Ki | 8.0 [1], 15.85 [2], 7998342.55 [3] |
 | (7-Methyl-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone | Ki | 7.0 [1], 12.59 [2], 6998419.96 [3] |
 | (4,5-Dichloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 5.0 [1], 6.31 [2], 5000345.35 [3] |
 | 8-Chloro-4-(4-methylpiperazin-1-yl)benzofuro[3,2-d]pyrimidine | IC50 | 19.0 [1] |
| 8-Chloro-4-(4-methylpiperazin-1-yl)benzofuro[3,2-d]pyrimidine | Ki | 4.7 [1], 5.0 [2], 19.0 [3] |
 | Piperazine, 1-((5-methoxyindol-2-yl)carbonyl)-4-methyl- | Ki | 1000.0 [1], 3000.0 [2], 5011.87 [3] |
 | (5-Methyl-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 46.0 [1], 50.12 [2], 46025657.36 [3] |
 | (7-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 19.0 [1], 19.95 [2], 19010782.8 [3] |
 | (5-Bromo-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone | Ki | 8.0 [1], 31.62 [2], 7998342.55 [3] |
 | [(3As,6aR)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5,6-difluoro-1H-benzimidazol-2-yl)methanimine | Ki | 9.5 [1], 10.0 [2], 17.2 [3] |
 | 4-(4-Chlorophenyl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine | Ki | 2.0 [1], 3.16 [2], 63.1 [3], 199.53 [4] |
 | N-(3,3-Dimethylbutyl)-6-(4-methylpiperazin-1-yl)pyrimidin-4-amine | Ki | 37.0 [1], 82.0 [2], 92.0 [3] |
 | [(3Ar,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5,6-difluoro-1H-benzimidazol-2-yl)methanone | Ki | 53.0 [1], 128.0 [2], 236.0 [3] |
 | 6-N-(3,3-Dimethylbutyl)-4-N-[(3S)-pyrrolidin-3-yl]pyrimidine-4,6-diamine | Ki | 502.0 [1], 572.0 [2] |
 | [(3Ar,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(5-chloro-1H-indol-2-yl)methanone | Ki | 16.0 [1], 27.0 [2] |
 | [(3Ar,6aS)-2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]-(6-fluoro-1H-benzimidazol-2-yl)methanone | Ki | 39.0 [1], 83.0 [2], 145.0 [3] |
 | Diphenhydramine | IC50 | 11000.0 [1] |
| Diphenhydramine | Ki | 11000.0 [1], 42657.95 [2] |
 | Dimaprit | Ki | 90.0 [1], 316.23 [2] |
 | Ciproxifan | Ki | 612.0 [1], 1862.09 [2] |
 | 2-(Diaminomethylideneamino)ethylsulfanylmethanimidamide | Ki | 25.12 [1], 31.62 [2] |
 | Impentamine | Ki | 251.19 [1], 2691530000000000.0 [2] |
 | 6,7-Dichloro-3-(4-methylpiperazin-1-yl)-1H-quinoxalin-2-one | Ki | 5.62 [1], 6.0 [2] |
 | 2-(4-Methylpiperazin-1-yl)quinazoline | Ki | 7585.78 [1] |
 | 6-Chloro-N-(furan-3-ylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine | IC50 | 144.54 [1] |
| 6-Chloro-N-(furan-3-ylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine | Ki | 26.92 [1], 89.13 [2] |
 | 1-Cyano-3-[[(2R,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine | Ki | 125.0 [1], 125.89 [2] |
 | 12-Chloro-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]-8-oxa-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaen-4-amine | Ki | 9.0 [1], 9.4 [2] |
 | 7-(Furan-2-yl)-4-piperazin-1-ylquinazolin-2-amine | IC50 | 106.0 [1] |
| 7-(Furan-2-yl)-4-piperazin-1-ylquinazolin-2-amine | Ki | 15.14 [1], 16.0 [2] |
 | [5-[[3-[[6-(3,3-Dimethylbutylamino)pyrimidin-4-yl]amino]pyrrolidin-1-yl]methyl]furan-2-yl]methanol | Ki | 2110.0 [1] |
 | (5,7-Dimethyl-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 31.0 [1], 30974192.99 [2] |
 | (4-Bromo-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 32.0 [1], 31988951.1 [2] |
 | (R)-8-Chloro-4-(3-(methylamino)pyrrolidin-1-yl)benzofuro[3,2-d]pyrimidin-2-amine | IC50 | 1.0 [1], 3.0 [2] |
| (R)-8-Chloro-4-(3-(methylamino)pyrrolidin-1-yl)benzofuro[3,2-d]pyrimidin-2-amine | Ki | 0.4 [1] |
 | (S)-8-Chloro-4-(3-(methylamino)pyrrolidin-1-yl)benzofuro[3,2-d]pyrimidin-2-amine | IC50 | 4.0 [1], 13.0 [2] |
| (S)-8-Chloro-4-(3-(methylamino)pyrrolidin-1-yl)benzofuro[3,2-d]pyrimidin-2-amine | Ki | 2.0 [1] |
 | 2-[[6-Chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-yl]amino]-N-phenylethanesulfonamide | IC50 | 33.11 [1] |
| 2-[[6-Chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-yl]amino]-N-phenylethanesulfonamide | Ki | 4.0 [1], 4.9 [2] |
 | (4-Methylpiperazin-1-yl)-(1H-pyrrolo[2,3-b]pyridin-2-yl)methanone | Ki | 1995.26 [1], 3100.0 [2], 29900.0 [3] |
 | 4-(4-Bromophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine | IC50 | 1630.0 [1] |
| 4-(4-Bromophenyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine | Ki | 520.0 [1], 524.0 [2] |
 | (5,7-Difluoro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 14.0 [1], 13995873.23 [2] |
 | (5,7-Dichloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone | Ki | 11.0 [1], 5000345.35 [2] |
 | (7-Bromo-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone | Ki | 61.0 [1], 61094202.49 [2] |
 | Clozapine | Ki | 199.53 [1], 501.19 [2] |
 | Ketotifen | IC50 | 21000.0 [1] |
| Ketotifen | Ki | 21000.0 [1] |
 | Desloratadine | IC50 | 16000.0 [1] |
| Desloratadine | Ki | 16000.0 [1] |
 | Impromidine | Ki | 12.3 [1], 25.12 [2] |
 | Burimamide | Ki | 39.81 [1], 180.0 [2] |
 | Pitolisant | Ki | 10000.0 [1], 100000.0 [2] |
 | Iodophenpropit | Ki | 7.8 [1], 16.0 [2] |
 | Iodoproxyfan | Ki | 12.59 [1] |
 | Methimepip | Ki | 1995.26 [1] |
 | Immethridine | Ki | 245.47 [1], 251.19 [2] |
 | 3-(1H-Imidazol-5-yl)propyl carbamimidothioate | Ki | 10.0 [1], 12.59 [2] |
 | 2-(4-Methylpiperazin-1-yl)quinoxaline | Ki | 891.25 [1], 1060.0 [2] |
 | 1H-Imidazole-4-propanamine | Ki | 31.62 [1], 2.88e+16 [2] |
 | 3-Benzyl-2-(4-methylpiperazinyl)-quinoxaline | Ki | 39.81 [1] |
 | (7As,11aS)-4-piperazin-1-yl-5,6,7a,8,9,10,11,11a-octahydro-[1]benzofuro[2,3-h]quinazolin-2-amine | Ki | 5.75 [1], 79.43 [2] |
 | 2-(2-(4-Tert-Butylphenylthio)ethyl)-1H-imidazole | Ki | 1.1 [1] |
 | 3-(4-Methylpiperazin-1-yl)-1H-quinoxalin-2-one | Ki | 61.66 [1], 63.1 [2] |
 | 5H-Benzo(6,7)cyclohepta(1,2-d)pyrimidin-2-amine, 4-((3R)-3-amino-1-pyrrolidinyl)-6,7-dihydro- | Ki | 4.7 [1], 5.0 [2] |
 | (4-(Piperazin-1-yl)-6,7-dihydro-5H-benzo(6,7)cyclohepta(1,2-d)pyrimidin-2-yl)amine | Ki | 71.0 [1], 79.43 [2] |
 | N-Benzyl-2-(4-methylpiperazin-1-yl)quinazolin-4-amine | Ki | 1071.52 [1] |
 | Imifuramine | Ki | 794.33 [1], 891.25 [2] |
 | 2-(4-Methylpiperazino)-4-quinazolinamine | Ki | 1737.8 [1], 2137.96 [2] |
 | (1R,2S)-trans-2-[2-(4-Chlorobenzylamino)ethyl]-1-(1H-imidazol-4-yl)cyclopropane | IC50 | 110.0 [1] |
| (1R,2S)-trans-2-[2-(4-Chlorobenzylamino)ethyl]-1-(1H-imidazol-4-yl)cyclopropane | Ki | 7.6 [1] |
 | 6-Chloro-2-(4-methylpiperazin-1-yl)quinazolin-4-amine | Ki | 104.71 [1], 154.88 [2] |
 | 4-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]benzonitrile | Ki | 34.67 [1], 35.0 [2] |
 | N4-Benzyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine | Ki | 20.0 [1], 98.0 [2] |
 | 6-Chloro-2-(4-methylpiperazin-1-yl)-N-propan-2-ylquinazolin-4-amine | Ki | 758.58 [1] |
 | 6-Chloro-N-(cyclohexylmethyl)-2-(4-methylpiperazin-1-yl)quinazolin-4-amine | Ki | 588.84 [1] |
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