High-affinity choline transporter Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	4-Methoxy-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	72.0 [1], 90.0 [2], 270.0 [3]
	4-Methoxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]-3-(1-propan-2-ylpiperidin-4-yl)oxybenzamide	IC50	100.0 [1], 240.0 [2]
	4-Methoxy-3-(1-propan-2-ylpiperidin-4-yl)oxy-N-(2-pyrrolidin-1-ylethyl)benzamide	IC50	1560.0 [1], 2130.0 [2]
	4-Methoxy-N-[(4-methyl-1,3-thiazol-2-yl)methyl]-3-(1-propan-2-ylpiperidin-4-yl)oxybenzamide	IC50	1020.0 [1], 3480.0 [2]
	4-Methoxy-N-[(2-methyl-1,3-thiazol-4-yl)methyl]-3-(1-propan-2-ylpiperidin-4-yl)oxybenzamide	IC50	1640.0 [1], 4930.0 [2]
	N-[(1-Ethylpyrazol-4-yl)methyl]-4-methoxy-3-(1-propan-2-ylpiperidin-4-yl)oxybenzamide	IC50	1850.0 [1], 9270.0 [2]
	N-[(1-Ethyl-3,5-dimethylpyrazol-4-yl)methyl]-4-methoxy-3-(1-propan-2-ylpiperidin-4-yl)oxybenzamide	IC50	910.0 [1], 1580.0 [2]
	N-[(1,5-Dimethylpyrazol-3-yl)methyl]-4-methoxy-3-(1-propan-2-ylpiperidin-4-yl)oxybenzamide	IC50	2510.0 [1], 8090.0 [2]
	4-Methoxy-3-(1-propan-2-ylpiperidin-4-yl)oxy-N-(1-pyridin-2-ylpropan-2-yl)benzamide	IC50	1730.0 [1], 4120.0 [2]
	4-Methoxy-3-(2-piperidin-1-ylethoxy)-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	530.0 [1], 760.0 [2]
	4-Methoxy-3-(2-morpholin-4-ylethoxy)-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	1770.0 [1], 6120.0 [2]
	4-Methoxy-3-(1-methylpiperidin-3-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	1250.0 [1], 4540.0 [2]
	4-(4-Butylpiperidin-1-yl)-1-o-tolylbutan-1-one	Ki	1000.0 [1]
	N-(1-Phenylethyl)-4-{[1-(pyridin-2-ylmethyl)piperidin-4-yl]oxy}benzamide	IC50	1260.0 [1]
	CID 24793028	IC50	3160.0 [1]
	CID 24791838	IC50	3360.0 [1]
	CID 24793288	IC50	760.0 [1]
	CID 24793407	IC50	600.0 [1]
	CID 24793875	IC50	4470.0 [1]
	CID 24819334	IC50	4220.0 [1]
	N-[1-[3-(3-Oxo-1,4-benzoxazin-4-yl)propyl]piperidin-4-yl]-2-phenylacetamide	Ki	1000.0 [1]
	4-Chloro-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	270.0 [1]
	(13Z)-21-Methyl-8,17-dioxa-19,21-diazatricyclo[16.2.1.02,7]henicosa-1(20),2,4,6,13,18-hexaene	IC50	3200.0 [1]
	3-Cyano-4-[2-[2-[(2-piperidin-4-ylethylamino)methyl]pyridin-4-yl]-4-[3-(trifluoromethyl)phenyl]phenoxy]-N-(1,2,4-thiadiazol-5-yl)benzenesulfonamide	IC50	120.0 [1]
	4-Fluoro-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	467.0 [1]
	3-(1-Methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]-4-(trifluoromethyl)benzamide	IC50	10000.0 [1]
	N-[(3-Propan-2-yl-1,2-oxazol-5-yl)methyl]-3-(1-propan-2-ylpiperidin-4-yl)oxybenzamide	IC50	1840.0 [1]
	4-Cyano-3-(1-methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	3350.0 [1]
	3-(1-Methylpiperidin-4-yl)oxy-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]benzamide	IC50	640.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 29 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ High-affinity choline transporter Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/high-affinity-choline-transporter-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ High-affinity choline transporter Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/high-affinity-choline-transporter-inhibitors-ic50-ki.
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