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Hexokinase type II Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
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▼
2,3-Dichloro-N-[[(2R,3S,4R,5R)-3,4,6-trihydroxy-5-[(3-phenylphenyl)sulfonylamino]oxan-2-yl]methyl]benzenesulfonamideIC5025.0 [1], 470.0 [2]
5-Chloro-N-[(3R,4R,5S,6R)-6-[[(2,3-dichlorophenyl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]thiophene-2-sulfonamideIC50130.0 [1], 520.0 [2]
N-[(3R,4R,5S,6R)-6-[[(2,3-Dichlorophenyl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]-3-phenylbenzamideIC5025.0 [1], 200.0 [2]
(E)-3-(3,4-Dichlorophenyl)-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]prop-2-enamideIC506300.0 [1]
(E)-3-(3,4-Dichlorophenyl)-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]prop-2-enamideKi2900.0 [1]
(E)-3-(3,4-Dichlorophenyl)-N-[(2R,3R,4R,5S,6R)-2,4,5-trihydroxy-6-[[(4-methylphenyl)sulfonylamino]methyl]oxan-3-yl]prop-2-enamideIC50316.23 [1]
3-Phenyl-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]benzamideIC503200.0 [1]
3-(4-Cyanophenyl)-5-(trifluoromethyl)-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]benzamideIC50790.0 [1]
2-[4-(Trifluoromethyl)cyclohexylidene]-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamideIC5016000.0 [1]
Methyl 5-[[(2R,3S,4R,5R)-5-[(3-bromobenzoyl)amino]-3,4,6-trihydroxyoxan-2-yl]methylsulfamoyl]-2-methylfuran-3-carboxylateIC50630.0 [1]
5-Chloro-N-[(3R,4R,5S,6R)-6-[[(2,3-dichlorophenyl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]thiophene-2-carboxamideIC5040.0 [1]
2,3-Dichloro-N-[[(2R,3S,4R,5R)-3,4,6-trihydroxy-5-[(3-nitrophenyl)sulfonylamino]oxan-2-yl]methyl]benzenesulfonamideIC50130.0 [1]
4-Phenyl-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]benzamideIC5016000.0 [1]
2,3-Dichloro-N-[[(2R,3S,4R,5R)-5-[[3-(4-chlorophenyl)phenyl]sulfonylamino]-3,4,6-trihydroxyoxan-2-yl]methyl]benzenesulfonamideIC507.9 [1]
2,3-Dichloro-N-[[(2R,3S,4R,5R)-5-[(3,4-dichlorophenyl)sulfonylamino]-3,4,6-trihydroxyoxan-2-yl]methyl]benzenesulfonamideIC5050.0 [1]
N-[(3R,4R,5S,6R)-6-[[(4-Chloropyridin-3-yl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]-3-phenylbenzamideIC50100.0 [1]
N-[(3R,4R,5S,6R)-6-[[(4-Cyanophenyl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]-3-phenylbenzamideIC50130.0 [1]
(E)-3-(3,4-Dichlorophenyl)-N-[(3S,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]prop-2-enamideIC50400000.0 [1]
N-[(3R,4R,5S,6R)-6-[[(2-Chlorophenyl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]-3-phenylbenzamideIC50100.0 [1]
N-[(3R,4R,5S,6R)-6-[[(3-Chlorophenyl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]-3-phenylbenzamideIC50320.0 [1]
N-[(3R,4R,5S,6R)-6-(Benzenesulfonamidomethyl)-2,4,5-trihydroxyoxan-3-yl]-3-phenylbenzamideIC50790.0 [1]
3-[[(2R,3S,4R,5R)-3,4,6-Trihydroxy-5-[(3-phenylbenzoyl)amino]oxan-2-yl]methylsulfamoyl]benzoic acidIC5050.0 [1]
5-[[(2R,3S,4R,5R)-5-[(3-Bromobenzoyl)amino]-3,4,6-trihydroxyoxan-2-yl]methylsulfamoyl]-2-methylfuran-3-carboxylic acidIC5010.0 [1]
(E)-3-(3,4-Dichlorophenyl)-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-[[(4-methylphenyl)sulfonylamino]methyl]oxan-3-yl]prop-2-enamideIC502000.0 [1]
(E)-3-(3,4-Dichlorophenyl)-N-[(3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-methoxyoxan-3-yl]prop-2-enamideIC50400000.0 [1]
3-(4-Cyanophenyl)-N-[(3R,4R,5S,6R)-6-[[(2,3-dichlorophenyl)sulfonylamino]methyl]-2,4,5-trihydroxyoxan-3-yl]-5-methoxybenzamideIC5025.0 [1]
3,5-Dinitro-N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]benzamideIC502000.0 [1]
Items per page: 1 - 10 of 27
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References

This online tool may be cited as follows

MLA

"Quest Database™ Hexokinase type II Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/hexokinase-type-ii-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Hexokinase type II Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/hexokinase-type-ii-inhibitors-ic50-ki.
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