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Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
CID 25262525IC508100.0 [1]
CID 25262525Ki2900.0 [1], 33870.0 [2]
Lyp-IN-1IC50250.0 [1], 259.0 [2]
Lyp-IN-1Ki110.0 [1]
3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-carbostyrilIC5013700.0 [1], 20600.0 [2]
3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-carbostyrilKi12480.0 [1], 38060.0 [2]
3-[2-(3-Chlorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC50990.0 [1], 1000.0 [2]
3-[[Benzyl-[(4-chlorophenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneIC509190.0 [1]
3-[[Benzyl-[(4-chlorophenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneKi8070.0 [1], 23890.0 [2]
3-[(4-Benzhydrylpiperazin-1-yl)-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneIC506310.0 [1]
3-[(4-Benzhydrylpiperazin-1-yl)-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneKi11040.0 [1], 21310.0 [2]
3-[[Benzyl-[(4-propan-2-ylphenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneIC505280.0 [1]
3-[[Benzyl-[(4-propan-2-ylphenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneKi2160.0 [1], 10650.0 [2]
3-[2-Azaspiro[5.5]undecan-2-yl-[1-(oxolan-2-yl)tetrazol-5-yl]methyl]-6-methyl-1H-quinolin-2-oneIC505580.0 [1]
3-[2-Azaspiro[5.5]undecan-2-yl-[1-(oxolan-2-yl)tetrazol-5-yl]methyl]-6-methyl-1H-quinolin-2-oneKi3070.0 [1], 17620.0 [2]
6-Hydroxy-2-phenyl-3-[2-[3-(trifluoromethyl)phenyl]ethynyl]benzofuran-5-carboxylic acidIC502000.0 [1]
3-[2-(3,5-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC501300.0 [1]
6-Hydroxy-2-phenyl-3-[2-[4-(trifluoromethoxy)phenyl]ethynyl]benzofuran-5-carboxylic acidIC502000.0 [1]
6-Hydroxy-2-phenyl-3-(2-phenylethynyl)benzofuran-5-carboxylic acidIC504900.0 [1]
3-[2-(3-Fluorophenyl)ethynyl]-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC503900.0 [1]
6-Hydroxy-3-[2-(3-methoxyphenyl)ethynyl]-2-phenyl-benzofuran-5-carboxylic acidIC5017000.0 [1]
3-[2-(2,4-Difluorophenyl)ethynyl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acidIC503500.0 [1]
6-Hydroxy-3-[2-(4-phenoxyphenyl)ethynyl]-2-phenyl-benzofuran-5-carboxylic acidIC50630.0 [1]
3-Ethynyl-6-hydroxy-2-phenyl-benzofuran-5-carboxylic acidIC5050000.0 [1]
4-[[4-[(E)-[5-[4-(Dimethylamino)phenyl]-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]methyl]benzoic acidIC506100.0 [1]
4-[[4-[(E)-[5-[4-(Dimethylamino)phenyl]-6-ethoxycarbonyl-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]methyl]benzoic acidKi2870.0 [1]
CID 1435211IC509900.0 [1], 22000.0 [2]
2-(3-Cyano-5,8-dimethylquinolin-2-yl)sulfanyl-N-(2-ethyl-6-methylphenyl)acetamideIC505400.0 [1], 11300.0 [2]
2-[1-(4-Methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]sulfanyl-1-(2-methyl-2,3-dihydroindol-1-yl)ethanoneIC5022000.0 [1], 80000.0 [2]
2-[(5,6-Dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamideIC506200.0 [1], 11200.0 [2]
2-[[6-(1,3-Dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]-N-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]acetamideIC5018500.0 [1]
2-[[6-(1,3-Dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]-N-[5-[(3-methylphenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]acetamideKi9970.0 [1]
4-[3-(4-Methoxyphenyl)-3-oxopropyl]-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]benzamideIC5010000.0 [1], 40000.0 [2]
3-Ethynyl-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acidIC504200.0 [1]
3-[2-(3-Chlorophenyl)ethynyl]-6-hydroxy-2-[4-(trifluoromethoxy)phenyl]-1-benzofuran-5-carboxylic acidIC50680.0 [1]
3-[2-(3-Chlorophenyl)ethynyl]-6-hydroxy-2-[3-[2-oxo-2-(4-propan-2-ylanilino)ethoxy]phenyl]-1-benzofuran-5-carboxylic acidIC50300.0 [1]
2-Hydroxy-1,4-naphthoquinoneIC505600.0 [1]
1,2-NaphthoquinoneIC501100.0 [1]
Naphthalene-1,2-diolIC502520.0 [1]
OxyresveratrolIC5031450.0 [1]
MorusinIC5014970.0 [1]
NorartocarpetinIC5030290.0 [1]
Cudraflavanone AIC509540.0 [1]
Cefsulodin sodium saltIC50200000.0 [1]
6-Hydroxy-1-methyl-3-[1-[3-oxo-3-(4-phenylanilino)propyl]triazol-4-yl]-2-phenylindole-5-carboxylic acidIC5025000.0 [1]
CID 6393068IC501900.0 [1]
CID 11839289IC504800.0 [1]
CID 11839290IC501000.0 [1]
CID 11839291IC501900.0 [1]
CID 2012945IC501300.0 [1]
2-((Z)-5-((E)-3-(Furan-2-yl)allylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acidIC502500.0 [1]
CID 71734765IC50171.0 [1]
CID 2030970IC50980.0 [1]
2-[4-[(E)-[5-(3-Methoxyphenyl)-7-methyl-3-oxo-6-(phenylcarbamoyl)-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]phenoxy]acetic acidIC5079500.0 [1]
3-[(1-Cyclopentyltetrazol-5-yl)-[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-6-methyl-1H-quinolin-2-oneIC5040000.0 [1]
2-[6-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-benzothiazol-2-ylsulfanyl]-N,N-dimethyl-acetamideIC50100000.0 [1]
5,7-Dichloro-4-((3-(4-methoxyphenylthio)benzyl)(methyl)amino)quinoline-2-carboxylic acidKi5530.0 [1]
3-[2-Azaspiro[5.5]undecan-2-yl-(1-cyclopentyltetrazol-5-yl)methyl]-8-methyl-1H-quinolin-2-oneIC5015750.0 [1]
[(1R,2S,6S)-2-[2,6-Dihydroxy-4-(6-hydroxy-1-benzofuran-2-yl)phenyl]-6-(2,4-dihydroxyphenyl)-4-methylcyclohex-3-en-1-yl]-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]methanoneIC507290.0 [1]
2-Methyl-3-[5-[(Z)-[3-[2-(4-methylanilino)-2-oxoethyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoic acidIC503300.0 [1]
N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamideIC5050000.0 [1]
2-(1,3-Benzothiazol-2-ylsulfanyl)-N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)acetamideIC50100000.0 [1]
2-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]phenoxy]acetic acidKi200000.0 [1]
2-(5-Methylfuran-2-yl)-N-[[3-[[[2-(5-methylfuran-2-yl)quinoline-4-carbonyl]amino]methyl]phenyl]methyl]quinoline-4-carboxamideKi17860.0 [1]
5-[(2S)-2-Acetamido-3-[4-(3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxopropyl]-2-(carboxymethoxy)benzoic acidKi129100.0 [1]
1,1,1,3,3,3-Hexafluoro-2-phenylpropan-2-olIC50500000.0 [1]
3-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]-N-oxaloanilino]-2-methylpropanoic acidKi16700.0 [1]
5-(4-Bromophenyl)-N-(2-pyridin-3-yl-1,3-benzoxazol-5-yl)furan-2-carboxamideKi14860.0 [1]
3-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]-N-oxaloanilino]pentanoic acidKi9300.0 [1]
5-[5-[(Z)-[3-(Carboxymethyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]-2-hydroxybenzoic acidIC508700.0 [1]
2-(1-Carboxyethoxy)-5-[(2S)-3-[4-(3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-3-oxopropyl]benzoic acidKi1970.0 [1]
3-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]-N-oxaloanilino]-2-phenylpropanoic acidKi97800.0 [1]
3-Chloro-N-(5-methyl-1,3-benzothiazol-2-yl)-1-benzothiophene-2-carboxamideIC5029500.0 [1]
2-[4-[[2-(4-Iodoanilino)-2-oxoacetyl]amino]anilino]-2-oxo-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-phenylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
2-Oxo-2-[4-[[2-oxo-2-(4-propan-2-ylanilino)acetyl]amino]anilino]-1-phenylethanesulfonic acidIC5050000.0 [1]
Kuwanon-GIC5018530.0 [1]
(2S)-2-[3-[(1R,5S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2,4-dihydroxyphenyl]-5,7-dihydroxy-2,3-dihydrochromen-4-oneIC5012120.0 [1]
5-[5-[(E)-[3-(Carboxymethyl)-2,4-dioxoimidazolidin-1-yl]iminomethyl]furan-2-yl]-2-hydroxybenzoic acidIC5036000.0 [1]
5-[5-[(E)-[3-(Carboxymethyl)-2,4-dioxoimidazolidin-1-yl]iminomethyl]thiophen-2-yl]-2-hydroxybenzoic acidIC5044000.0 [1]
Methyl 5-[5-[(E)-(2,4-dioxoimidazolidin-1-yl)iminomethyl]thiophen-2-yl]-2-hydroxybenzoateIC5044000.0 [1]
5-[5-[(E)-(2,4-Dioxoimidazolidin-1-yl)iminomethyl]thiophen-2-yl]-2-hydroxybenzoic acidIC5034000.0 [1]
Methyl 5-[5-[(E)-(2,4-dioxoimidazolidin-1-yl)iminomethyl]furan-2-yl]-2-hydroxybenzoateIC5044000.0 [1]
5-[5-[(E)-(2,4-Dioxoimidazolidin-1-yl)iminomethyl]furan-2-yl]-2-hydroxybenzoic acidIC5044000.0 [1]
2-(3-Cyano-7-methoxyquinolin-2-yl)sulfanyl-N-(2,3-dimethylphenyl)acetamideIC5030500.0 [1]
1-[(E)-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]methylideneamino]-3-(4-methylphenyl)thioureaIC5050000.0 [1]
1-Naphthalen-1-yl-3-[(E)-(4-phenylphenyl)methylideneamino]thioureaIC5050000.0 [1]
1-Naphthalen-1-yl-3-[(E)-(4-nitrophenyl)methylideneamino]thioureaIC5050000.0 [1]
1-[(E)-[5-[2-Chloro-5-(trifluoromethyl)phenyl]furan-2-yl]methylideneamino]-3-naphthalen-1-ylthioureaIC5050000.0 [1]
Methyl 2-[[2-[[6-(1,3-dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetyl]amino]benzoateIC50100000.0 [1]
3-[[4-[(E)-[6-Ethoxycarbonyl-5-(4-methoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene]methyl]-2-methoxyphenoxy]methyl]benzoic acidIC507100.0 [1]
N'-[1-[4-(4-Fluorophenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]-N-(pyridin-3-ylmethyl)oxamideIC5050000.0 [1]
N-(Furan-2-ylmethyl)-N'-[1-[4-(4-methoxyphenyl)piperazin-1-yl]-1-thiophen-2-ylpropan-2-yl]oxamideIC5050000.0 [1]
2-[4-[3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]phenoxy]propanedioic acidKi24780.0 [1]
2-[4-[(E)-(6-Ethoxycarbonyl-7-methyl-3-oxo-5-phenyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-2-ylidene)methyl]phenoxy]acetic acidIC5036500.0 [1]
Ethyl (2E)-2-[(4-hydroxyphenyl)methylidene]-7-methyl-3-oxo-5-(4-propan-2-yloxyphenyl)-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylateIC5042000.0 [1]
8-[(1R,5S,6R)-6-[2,4-Dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-oneIC5011750.0 [1]
Methyl 2-hydroxy-5-[5-[(Z)-[3-(3-methoxy-3-oxopropyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoateIC5044000.0 [1]
5-(3-Chloro-2-methylphenyl)-N-(9,10-dioxo-9,10-dihydro-2-anthracenyl)-2-furamideKi19170.0 [1]
3-[[Benzyl-[(4-methoxyphenyl)methyl]amino]-(1-cyclopentyltetrazol-5-yl)methyl]-6-methyl-1H-quinolin-2-oneIC5013030.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/hematopoietic-cell-protein-tyrosine-phosphatase-70z-pep-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/hematopoietic-cell-protein-tyrosine-phosphatase-70z-pep-inhibitors-ic50-ki.
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