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Heat shock protein 75 kDa, mitochondrial Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
LuminespibIC5038.0 [1], 500.0 [2], 535.0 [3]
LuminespibKi16.0 [1]
PU-H71IC50205.0 [1], 257.0 [2]
6-Chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amineIC5090.0 [1], 535.0 [2]
6-Chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amineKi62.0 [1]
Snx-2112IC50726.0 [1]
Snx-2112Ki791.0 [1]
Adenosine-5'-triphosphateIC5031303.0 [1]
Adenosine-5'-diphosphateIC5055594.0 [1]
GeldanamycinIC50661.0 [1]
TanespimycinIC501496.0 [1]
GanetespibIC5051.0 [1]
Nvp-hsp990(hsp990)IC50200.0 [1]
Debio 0932IC501586.0 [1]
CID 67495834Ki1195.0 [1]
5-[2-Amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]-2-methylpent-4-yn-2-olKi255.0 [1]
8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amineIC507300.0 [1]
9-(Pent-4-yn-1-yl)-8-((2,4,5-trichlorophenyl)thio)-9H-purin-6-amineIC5078400.0 [1]
8-((2,4-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amineIC5013800.0 [1]
8-((2,5-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amineIC505100.0 [1]
8-((3,5-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amineIC50157900.0 [1]
8-((2,4-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amineIC50145400.0 [1]
8-((3,5-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amineIC5083600.0 [1]
8-((2,5-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amineIC50203700.0 [1]
5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-(3-morpholin-4-ylpropanoylamino)-1,2-oxazole-3-carboxamideIC5020000.0 [1]
5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[(4-methoxybenzoyl)amino]-1,2-oxazole-3-carboxamideIC50400.0 [1]
8-(Mesitylthio)-9-(pent-4-yn-1-yl)-9H-purin-6-amineIC5065500.0 [1]
8-(2,4-Dichlorophenyl)sulfanyl-9-pentan-2-ylpurin-6-amineIC5050000.0 [1]
9-Pent-4-ynyl-8-(2,3,4-trichlorophenyl)sulfanylpurin-6-amineIC503600.0 [1]
8-(3,5-Dichlorophenyl)sulfanyl-9-(2-phenylethyl)purin-6-amineIC50100000.0 [1]
8-(2,6-Dichloropyridin-4-yl)sulfanyl-9-pent-4-ynylpurin-6-amineIC509600.0 [1]
(6-Amino-9-pent-4-ynylpurin-8-yl)-(2,4-dichlorophenyl)methanoneIC504980.0 [1]
4-[6-Amino-8-(3,5-dichlorophenyl)sulfanylpurin-9-yl]butanenitrileIC504580.0 [1]
8-(2,4-Dichlorophenyl)sulfanyl-9-hex-5-yn-3-ylpurin-6-amineIC5050000.0 [1]
2-(2,4-Dichlorophenyl)sulfanyl-1-[3-(propan-2-ylamino)propyl]imidazo[4,5-c]pyridin-4-amineIC5014100.0 [1]
2-(3,5-Dichlorophenyl)sulfanyl-1-[3-(propan-2-ylamino)propyl]imidazo[4,5-c]pyridin-4-amineIC507200.0 [1]
9-But-3-ynyl-8-(2,4-dichlorophenyl)sulfanylpurin-6-amineIC507230.0 [1]
1-[(6-Bromo-1,3-benzodioxol-5-yl)methyl]-4-chloropyrazolo[3,4-d]pyrimidin-6-amineIC5079.0 [1]
1-(1,3-Benzodioxol-5-ylmethyl)-4-chloropyrazolo[3,4-d]pyrimidin-6-amineIC506335.0 [1]
4-[6-Imino-8-(2,4,5-trichlorophenyl)sulfanyl-7H-purin-3-yl]butanenitrileIC5019500.0 [1]
3-[8-(3,5-Dichlorophenyl)sulfanyl-6-imino-7H-purin-3-yl]-N-propan-2-ylpropan-1-amineIC50100000.0 [1]
4-[8-(2,4-Dichlorophenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrileIC509600.0 [1]
4-[8-(2,4-Dimethylphenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrileIC5054100.0 [1]
2-Amino-7-(1,3-benzodioxol-5-ylmethyl)-4-chloropyrrolo[2,3-d]pyrimidine-6-carboxylic acidIC508434.0 [1]
7-(1,3-Benzodioxol-5-ylmethyl)-4-chloroimidazo[5,1-f][1,2,4]triazin-2-amineIC5010000.0 [1]
5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-(6-pyridin-1-ium-1-ylhexanoylamino)-1,2-oxazole-3-carboxamide;bromideIC5010000.0 [1]
[6-[[5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-3-(ethylcarbamoyl)-1,2-oxazol-4-yl]amino]-6-oxohexyl]-triphenylphosphanium;bromideIC5025000.0 [1]
N-[3-[2-(3-Aminopropylamino)ethylamino]propyl]-N'-[5-(2,4-dihydroxy-5-propan-2-ylphenyl)-3-(ethylcarbamoyl)-1,2-oxazol-4-yl]hexanediamideIC505000.0 [1]
4-N-(Diaminomethylidene)-1-N-[5-(2,4-dihydroxy-5-propan-2-ylphenyl)-3-(ethylcarbamoyl)-1,2-oxazol-4-yl]benzene-1,4-dicarboxamideIC50500.0 [1]
4-[7-[4-(Diaminomethylidenecarbamoyl)phenyl]heptanoylamino]-5-(2,4-dihydroxy-5-propan-2-ylphenyl)-N-ethyl-1,2-oxazole-3-carboxamideIC503000.0 [1]
4-Chloro-1-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrazolo[3,4-d]pyrimidin-6-amineIC50138.0 [1]
[(4E,6Z,8R,9S,10E,12S,13R,14S,16R)-19-[2-(Dimethylamino)ethylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamateKi326.0 [1]
8-(2-Methylpropyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-Cyclopentyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-Cyclohexyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-(Oxan-4-yl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-Cyclobutyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-Butyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-Tert-butyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-Benzyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-Phenyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-(4-Fluorophenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-(3-Fluorophenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
8-(4-Methoxyphenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-oneKi10000.0 [1]
2-Fluoro-6-[[(3S)-oxolan-3-yl]amino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi8500.0 [1]
2-[[(3S)-Oxolan-3-yl]amino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi5000.0 [1]
2-(Cyclopentylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi1700.0 [1]
2-(Cyclopropylmethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi4500.0 [1]
2-(2-Methoxyethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi8800.0 [1]
2-(Thian-4-ylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi1200.0 [1]
2-(Propylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi5800.0 [1]
2-(Cyclopropylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi10000.0 [1]
2-(2,2-Difluoroethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi7400.0 [1]
2-[(3-Methyloxetan-3-yl)methylamino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi1200.0 [1]
2-(Propan-2-ylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi10000.0 [1]
2-(2,2-Dimethylpropylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi1400.0 [1]
2,7,7-Trimethyl-9-[1-oxo-8-(propan-2-ylamino)-3,4-dihydro-2H-isoquinolin-6-yl]-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-oneKi10000.0 [1]
2,7,7-Trimethyl-9-(1-oxo-2,3-dihydroisoindol-5-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-oneKi10000.0 [1]
2,7,7-Trimethyl-9-(1-oxo-3,4-dihydro-2H-isoquinolin-6-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-oneKi10000.0 [1]
2,7,7-Trimethyl-9-(1-oxo-2,3,4,5-tetrahydro-2-benzazepin-7-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-oneKi10000.0 [1]
2-(2-Cyclopropylethyl)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamideKi10000.0 [1]
2,7,7-Trimethyl-9-[8-(2-methylpropyl)-1-oxo-3,4-dihydro-2H-isoquinolin-6-yl]-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-oneKi10000.0 [1]
4-(2,8,8-Trimethyl-6-oxo-1,3,4,5,5a,7,9,10a-octahydroazepino[3,4-b]indol-10-yl)benzamideKi10000.0 [1]
4-(7,7-Dimethyl-5-oxo-1,2,3,4,6,8-hexahydropyrido[3,4-b]indol-9-yl)benzamideKi10000.0 [1]
4-(7,7-Dimethyl-9-oxo-6,8-dihydropyrido[3,2-b]indol-5-yl)benzamideKi10000.0 [1]
4-(7,7-Dimethyl-5-oxo-6,8-dihydropyrido[3,4-b]indol-9-yl)benzamideKi10000.0 [1]
4-(7,7-Dimethyl-5-oxo-6,8-dihydropyrido[2,3-b]indol-9-yl)benzamideKi10000.0 [1]
4-(7,7-Dimethyl-5-oxo-1,2,3,4,6,8-hexahydrocarbazol-9-yl)benzamideKi10000.0 [1]
4-(2,7,7-Trimethyl-5-Oxo-1,2,3,4,5,6,7,8-Octahydro-9h-beta-Carbolin-9-Yl)benzamideKi10000.0 [1]
Items per page: 1 - 10 of 89
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References

This online tool may be cited as follows

MLA

"Quest Database™ Heat shock protein 75 kDa, mitochondrial Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/heat-shock-protein-75-kda-mitochondrial-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Heat shock protein 75 kDa, mitochondrial Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/heat-shock-protein-75-kda-mitochondrial-inhibitors-ic50-ki.
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