| Luminespib | IC50 | 38.0 [1], 500.0 [2], 535.0 [3] |
| Luminespib | Ki | 16.0 [1] |
| PU-H71 | IC50 | 205.0 [1], 257.0 [2] |
| 6-Chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine | IC50 | 90.0 [1], 535.0 [2] |
| 6-Chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine | Ki | 62.0 [1] |
| Snx-2112 | IC50 | 726.0 [1] |
| Snx-2112 | Ki | 791.0 [1] |
| Adenosine-5'-triphosphate | IC50 | 31303.0 [1] |
| Adenosine-5'-diphosphate | IC50 | 55594.0 [1] |
| Geldanamycin | IC50 | 661.0 [1] |
| Tanespimycin | IC50 | 1496.0 [1] |
| Ganetespib | IC50 | 51.0 [1] |
| Nvp-hsp990(hsp990) | IC50 | 200.0 [1] |
| Debio 0932 | IC50 | 1586.0 [1] |
| CID 67495834 | Ki | 1195.0 [1] |
| 5-[2-Amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrrolo[2,3-d]pyrimidin-5-yl]-2-methylpent-4-yn-2-ol | Ki | 255.0 [1] |
| 8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine | IC50 | 7300.0 [1] |
| 9-(Pent-4-yn-1-yl)-8-((2,4,5-trichlorophenyl)thio)-9H-purin-6-amine | IC50 | 78400.0 [1] |
| 8-((2,4-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine | IC50 | 13800.0 [1] |
| 8-((2,5-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine | IC50 | 5100.0 [1] |
| 8-((3,5-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine | IC50 | 157900.0 [1] |
| 8-((2,4-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine | IC50 | 145400.0 [1] |
| 8-((3,5-Dichlorophenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine | IC50 | 83600.0 [1] |
| 8-((2,5-Dimethylphenyl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine | IC50 | 203700.0 [1] |
| 5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-(3-morpholin-4-ylpropanoylamino)-1,2-oxazole-3-carboxamide | IC50 | 20000.0 [1] |
| 5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[(4-methoxybenzoyl)amino]-1,2-oxazole-3-carboxamide | IC50 | 400.0 [1] |
| 8-(Mesitylthio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine | IC50 | 65500.0 [1] |
| 8-(2,4-Dichlorophenyl)sulfanyl-9-pentan-2-ylpurin-6-amine | IC50 | 50000.0 [1] |
| 9-Pent-4-ynyl-8-(2,3,4-trichlorophenyl)sulfanylpurin-6-amine | IC50 | 3600.0 [1] |
| 8-(3,5-Dichlorophenyl)sulfanyl-9-(2-phenylethyl)purin-6-amine | IC50 | 100000.0 [1] |
| 8-(2,6-Dichloropyridin-4-yl)sulfanyl-9-pent-4-ynylpurin-6-amine | IC50 | 9600.0 [1] |
| (6-Amino-9-pent-4-ynylpurin-8-yl)-(2,4-dichlorophenyl)methanone | IC50 | 4980.0 [1] |
| 4-[6-Amino-8-(3,5-dichlorophenyl)sulfanylpurin-9-yl]butanenitrile | IC50 | 4580.0 [1] |
| 8-(2,4-Dichlorophenyl)sulfanyl-9-hex-5-yn-3-ylpurin-6-amine | IC50 | 50000.0 [1] |
| 2-(2,4-Dichlorophenyl)sulfanyl-1-[3-(propan-2-ylamino)propyl]imidazo[4,5-c]pyridin-4-amine | IC50 | 14100.0 [1] |
| 2-(3,5-Dichlorophenyl)sulfanyl-1-[3-(propan-2-ylamino)propyl]imidazo[4,5-c]pyridin-4-amine | IC50 | 7200.0 [1] |
| 9-But-3-ynyl-8-(2,4-dichlorophenyl)sulfanylpurin-6-amine | IC50 | 7230.0 [1] |
| 1-[(6-Bromo-1,3-benzodioxol-5-yl)methyl]-4-chloropyrazolo[3,4-d]pyrimidin-6-amine | IC50 | 79.0 [1] |
| 1-(1,3-Benzodioxol-5-ylmethyl)-4-chloropyrazolo[3,4-d]pyrimidin-6-amine | IC50 | 6335.0 [1] |
| 4-[6-Imino-8-(2,4,5-trichlorophenyl)sulfanyl-7H-purin-3-yl]butanenitrile | IC50 | 19500.0 [1] |
| 3-[8-(3,5-Dichlorophenyl)sulfanyl-6-imino-7H-purin-3-yl]-N-propan-2-ylpropan-1-amine | IC50 | 100000.0 [1] |
| 4-[8-(2,4-Dichlorophenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile | IC50 | 9600.0 [1] |
| 4-[8-(2,4-Dimethylphenyl)sulfanyl-6-imino-7H-purin-3-yl]butanenitrile | IC50 | 54100.0 [1] |
| 2-Amino-7-(1,3-benzodioxol-5-ylmethyl)-4-chloropyrrolo[2,3-d]pyrimidine-6-carboxylic acid | IC50 | 8434.0 [1] |
| 7-(1,3-Benzodioxol-5-ylmethyl)-4-chloroimidazo[5,1-f][1,2,4]triazin-2-amine | IC50 | 10000.0 [1] |
| 5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-(6-pyridin-1-ium-1-ylhexanoylamino)-1,2-oxazole-3-carboxamide;bromide | IC50 | 10000.0 [1] |
| [6-[[5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-3-(ethylcarbamoyl)-1,2-oxazol-4-yl]amino]-6-oxohexyl]-triphenylphosphanium;bromide | IC50 | 25000.0 [1] |
| N-[3-[2-(3-Aminopropylamino)ethylamino]propyl]-N'-[5-(2,4-dihydroxy-5-propan-2-ylphenyl)-3-(ethylcarbamoyl)-1,2-oxazol-4-yl]hexanediamide | IC50 | 5000.0 [1] |
| 4-N-(Diaminomethylidene)-1-N-[5-(2,4-dihydroxy-5-propan-2-ylphenyl)-3-(ethylcarbamoyl)-1,2-oxazol-4-yl]benzene-1,4-dicarboxamide | IC50 | 500.0 [1] |
| 4-[7-[4-(Diaminomethylidenecarbamoyl)phenyl]heptanoylamino]-5-(2,4-dihydroxy-5-propan-2-ylphenyl)-N-ethyl-1,2-oxazole-3-carboxamide | IC50 | 3000.0 [1] |
| 4-Chloro-1-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]pyrazolo[3,4-d]pyrimidin-6-amine | IC50 | 138.0 [1] |
| [(4E,6Z,8R,9S,10E,12S,13R,14S,16R)-19-[2-(Dimethylamino)ethylamino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate | Ki | 326.0 [1] |
| 8-(2-Methylpropyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-Cyclopentyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-Cyclohexyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-(Oxan-4-yl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-Cyclobutyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-Butyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-Tert-butyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-Benzyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-Phenyl-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-(4-Fluorophenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-(3-Fluorophenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 8-(4-Methoxyphenyl)-6-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)-3,4-dihydro-2H-isoquinolin-1-one | Ki | 10000.0 [1] |
| 2-Fluoro-6-[[(3S)-oxolan-3-yl]amino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 8500.0 [1] |
| 2-[[(3S)-Oxolan-3-yl]amino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 5000.0 [1] |
| 2-(Cyclopentylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 1700.0 [1] |
| 2-(Cyclopropylmethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 4500.0 [1] |
| 2-(2-Methoxyethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 8800.0 [1] |
| 2-(Thian-4-ylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 1200.0 [1] |
| 2-(Propylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 5800.0 [1] |
| 2-(Cyclopropylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 10000.0 [1] |
| 2-(2,2-Difluoroethylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 7400.0 [1] |
| 2-[(3-Methyloxetan-3-yl)methylamino]-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 1200.0 [1] |
| 2-(Propan-2-ylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 10000.0 [1] |
| 2-(2,2-Dimethylpropylamino)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 1400.0 [1] |
| 2,7,7-Trimethyl-9-[1-oxo-8-(propan-2-ylamino)-3,4-dihydro-2H-isoquinolin-6-yl]-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one | Ki | 10000.0 [1] |
| 2,7,7-Trimethyl-9-(1-oxo-2,3-dihydroisoindol-5-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one | Ki | 10000.0 [1] |
| 2,7,7-Trimethyl-9-(1-oxo-3,4-dihydro-2H-isoquinolin-6-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one | Ki | 10000.0 [1] |
| 2,7,7-Trimethyl-9-(1-oxo-2,3,4,5-tetrahydro-2-benzazepin-7-yl)-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one | Ki | 10000.0 [1] |
| 2-(2-Cyclopropylethyl)-4-(2,7,7-trimethyl-5-oxo-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-9-yl)benzamide | Ki | 10000.0 [1] |
| 2,7,7-Trimethyl-9-[8-(2-methylpropyl)-1-oxo-3,4-dihydro-2H-isoquinolin-6-yl]-3,4,6,8-tetrahydro-1H-pyrido[3,4-b]indol-5-one | Ki | 10000.0 [1] |
| 4-(2,8,8-Trimethyl-6-oxo-1,3,4,5,5a,7,9,10a-octahydroazepino[3,4-b]indol-10-yl)benzamide | Ki | 10000.0 [1] |
| 4-(7,7-Dimethyl-5-oxo-1,2,3,4,6,8-hexahydropyrido[3,4-b]indol-9-yl)benzamide | Ki | 10000.0 [1] |
| 4-(7,7-Dimethyl-9-oxo-6,8-dihydropyrido[3,2-b]indol-5-yl)benzamide | Ki | 10000.0 [1] |
| 4-(7,7-Dimethyl-5-oxo-6,8-dihydropyrido[3,4-b]indol-9-yl)benzamide | Ki | 10000.0 [1] |
| 4-(7,7-Dimethyl-5-oxo-6,8-dihydropyrido[2,3-b]indol-9-yl)benzamide | Ki | 10000.0 [1] |
| 4-(7,7-Dimethyl-5-oxo-1,2,3,4,6,8-hexahydrocarbazol-9-yl)benzamide | Ki | 10000.0 [1] |
| 4-(2,7,7-Trimethyl-5-Oxo-1,2,3,4,5,6,7,8-Octahydro-9h-beta-Carbolin-9-Yl)benzamide | Ki | 10000.0 [1] |