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Glycogen synthase kinase-3 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
6-Bromoindirubin-3'-oximeIC505.0 [1], 290.0 [2]
IndirubinIC501000.0 [1], 2500.0 [2]
Indirubin-3'-monoximeIC5022.0 [1]
HarmineIC5010000.0 [1]
SeliciclibIC5060000.0 [1], 130000.0 [2]
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dioneIC502000.0 [1], 7000.0 [2]
AlsterpaulloneIC504.0 [1], 5.0 [2]
(3Z)-5-Methyl-3-(3-oxoindolin-2-ylidene)indolin-2-oneIC5062.0 [1], 800.0 [2]
1-(3-Methoxyphenyl)-N-[(E)-pyridin-4-ylmethylideneamino]pyrazolo[3,4-d]pyrimidin-4-amineIC506.31 [1]
6-Bromo-3-[(3E)-3-(2-piperazin-1-ylethoxyimino)indol-2-yl]-1H-indol-2-olIC50150.0 [1], 220.0 [2]
3-[[5-[6-[(3-Chlorophenyl)amino]pyrazinyl]-3-pyridinyl]amino]-1-propanolIC50478.0 [1]
3-(3-(Hydroxyimino)indolin-2-ylidene)-1-methylindolin-2-oneIC50100000.0 [1]
5,6-Dichloro-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-olIC504.0 [1]
N-(2-(Dimethylamino)ethyl)-8-isopropyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidineIC50560.0 [1]
8-Ethyl-N-isopropyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidineIC507200.0 [1]
N,8-Diisopropyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidineIC509400.0 [1]
2-(1-Methyl-2-oxoindolin-3-ylidene)indolin-3-oneIC50100000.0 [1]
N-(2-(Dimethylamino)ethyl)-8-ethyl-9-oxo-8,9-dihydrothiazolo[5,4-f]quinazoline-2-carboxamidineIC501300.0 [1]
LithiumIC502000000.0 [1]
QuercetinIC502100.0 [1]
StaurosporineIC5012.0 [1]
ApigeninIC501400.0 [1]
KaempferolIC503500.0 [1]
LuteolinIC50800.0 [1]
MaleimideIC506000.0 [1]
AlvocidibIC50280.0 [1]
ChrysinIC507200.0 [1]
Maleic anhydrideIC50100000.0 [1]
IndigoIC50100000.0 [1]
FisetinIC50420.0 [1]
2,4-ThiazolidinedioneIC50100000.0 [1]
RhodanineIC50100000.0 [1]
3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dioneIC5075.0 [1]
SuccinimideIC50100000.0 [1]
3-(3-Chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dioneIC50130.0 [1]
KenpaulloneIC5023.0 [1]
1-AzakenpaulloneIC5018.0 [1]
(5Z)-5-(Quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-oneKi500.0 [1]
N-MethylmaleimideIC505000.0 [1]
(3Z)-3-(1H-Imidazol-5-ylmethylene)-5-methoxy-1H-indol-2(3H)-oneIC50350.0 [1]
RepSoxIC5016000.0 [1]
4-({5-Amino-1-[(2,6-Difluorophenyl)carbonyl]-1h-1,2,4-Triazol-3-Yl}amino)benzenesulfonamideIC5041.0 [1]
4-PhenylurazoleIC50100000.0 [1]
PDGF Receptor Tyrosine Kinase Inhibitor IVIC5013000.0 [1]
HydantoinIC50100000.0 [1]
7-Bromo-3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-oneIC5032000.0 [1]
N-BenzylmaleimideIC501000.0 [1]
4-Cyclopentene-1,3-dioneIC5012000.0 [1]
1,3-CyclopentanedioneIC50100000.0 [1]
4-(7-Butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenolIC50645.65 [1]
N-(5-Methyl-1H-pyrazol-3-yl)-2-phenylquinazolin-4-amineKi24.0 [1]
IKK-3 InhibitorIC5015848.93 [1]
Cdk1/2 Inhibitor IIIIC50140.0 [1]
GSK-3 Inhibitor IIIC508000.0 [1]
3-Imidazo[1,2-a]pyridin-3-yl-4-[10-(morpholine-4-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]pyrrole-2,5-dioneIC501.3 [1]
Indirubin deriv. 8aIC5010.0 [1]
7-Butyl-6-(4-methoxyphenyl)-5H-pyrrolo[2,3-b]pyrazineIC50912.01 [1]
Pyrazolopyridazine 1aIC50250.0 [1]
3-Thiazolidineacetic acid, 4-oxo-2-thioxo-IC50100000.0 [1]
Leucettamine BIC5015000.0 [1]
3-(4-{4-Aminofuro[2,3-d]pyrimidin-5-yl}phenyl)-1-[2-fluoro-5-(trifluoromethyl)phenyl]ureaIC502187.76 [1]
7-BromoindirubinIC50100000.0 [1]
Indirubin 2IC5016.0 [1]
(2Z)-5'-Bromo-2,3'-biindole-2',3(1H,1'H)-dione ammoniateIC5055.0 [1]
5-Iodo-Indirubin-3'-monoximeIC509.0 [1]
3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-5-iodo-2H-indol-2-oneIC5068.0 [1]
PimodivirKi1600.0 [1]
1-Benzyl-2-pyrrolidinoneIC50100000.0 [1]
Indirubin deriv. 12aIC5022000.0 [1]
Maleimide, N-phenethyl-IC502000.0 [1]
(3Z)-5-Fluoro-3-(3-oxoindolin-2-ylidene)indolin-2-oneIC5078.0 [1]
(3Z)-5-Chloro-3-(3-oxoindolin-2-ylidene)indolin-2-oneIC5050.0 [1]
2-(3-Hydroxy-4-methoxystyryl)-8-hydroxyquinoline-7-carboxylic acidIC5010000.0 [1]
3-MethylrhodanineIC50100000.0 [1]
5-Nitro-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-oneIC5042.0 [1]
6-BromoindirubinIC5045.0 [1]
7-Fluoro-3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-oneIC50270.0 [1]
3-(6-Bromo-3-nitroso-1H-indol-2-yl)-1H-indol-2-olIC50340.0 [1]
1-Benzyl-3-pyrrolineIC50100000.0 [1]
5-Phenyl-1H-pyrazolo[3,4-c]pyridazin-3-amineIC50530.0 [1]
3-BenzylrhodanineIC5025000.0 [1]
4,14-Diazapentacyclo[11.7.0.02,6.07,12.015,20]icosa-1(13),2(6),7,9,11,15,17,19-octaene-3,5-dioneIC5020000.0 [1]
7-Bromo-1-methyl-3-(3-nitroso-1H-indol-2-yl)indol-2-olIC50100000.0 [1]
7-ChloroindirubinIC50100000.0 [1]
7-FluoroindirubinIC50400.0 [1]
2-(2-Hydroxy-5-methoxy-1H-indol-3-yl)indol-3-oneIC50800.0 [1]
MeBIOIC50100000.0 [1]
2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-oneIC50450.0 [1]
5-Bromo-2-(2-hydroxy-1H-indol-3-yl)indol-3-oneIC50350.0 [1]
6,11-Dihydroxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-oneIC5010000.0 [1]
4-Benzyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dioneIC507000.0 [1]
5-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-amineIC50430.0 [1]
N-AminorhodanineIC50100000.0 [1]
3-(4-Imidazo[1,2-a]pyridin-3-yl-2,5-dioxopyrrol-3-yl)-N,N-dimethyl-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraene-10-carboxamideIC501.6 [1]
N-Cyclopropyl-2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5-yl)methylamino)benzamideIC505000.0 [1]
2-(2-Hydroxy-1H-indol-3-yl)-5-methoxyindol-3-oneIC50600.0 [1]
Indirubin deriv. 5dIC50140.0 [1]
2-(2-Hydroxy-7-iodo-1H-indol-3-yl)indol-3-oneIC50100000.0 [1]
7-Iodo-3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-olIC5016000.0 [1]
(3Z)-6-Chloro-3-[(3E)-3-hydroxyiminoindolin-2-ylidene]indolin-2-oneIC5020.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Glycogen synthase kinase-3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/glycogen-synthase-kinase-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Glycogen synthase kinase-3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glycogen-synthase-kinase-3-inhibitors-ic50-ki.
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