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Glutathione S-transferase A2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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2-[2-(4-Amino-4-carboxybutyrylamino)-3-oxo-3-(carboxymethylamino)propylthio]succinic acidIC5019100.0 [1]
(4S)-4-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-2-methylpropanoyl]amino]-3-[4-(phosphonomethyl)phenyl]propanoyl]amino]-3-(6-chloro-1H-indol-3-yl)propanoyl]amino]-5-[[1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]carbamoyl]cyclopropyl]amino]-5-oxopentanoic acidIC505.0 [1]
[(3S,4S,5R)-3,4,5-Trihydroxy-6-oxocyclohexen-1-yl]methyl acetateIC50100000.0 [1]
[(4R,5S,6R)-4,5,6-Trihydroxy-3-oxocyclohexen-1-yl]methyl acetateIC50100000.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-3-(1,4-dimethoxy-1,4-dioxobutan-2-yl)sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acidIC50250000.0 [1]
[(3S,4R,5R)-4,5-Dihydroxy-3-methoxy-6-oxocyclohexen-1-yl]methyl acetateIC50100000.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-1-oxo-3-(4-oxohexan-2-ylsulfanyl)propan-2-yl]amino]-5-oxopentanoic acidIC5090000.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-1-oxo-3-(3-oxocyclohexyl)sulfanylpropan-2-yl]amino]-5-oxopentanoic acidIC50220000.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-1-oxo-3-(5-oxohexan-3-ylsulfanyl)propan-2-yl]amino]-5-oxopentanoic acidIC504100.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-3-(2-methyl-5-oxohexan-3-yl)sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acidIC5066000.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-1-oxo-3-(3-oxo-1-phenylbutyl)sulfanylpropan-2-yl]amino]-5-oxopentanoic acidIC5041000.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-1-oxo-3-(2-oxoheptan-4-ylsulfanyl)propan-2-yl]amino]-5-oxopentanoic acidIC508400.0 [1]
2-Amino-5-[[3-(3-butoxy-1-carboxy-3-oxopropyl)sulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acidIC5048000.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-3-(1,4-dioxo-1,4-dipropoxybutan-2-yl)sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acidIC50143300.0 [1]
2-Amino-5-[[1-(carboxymethylamino)-3-(4-methyl-3-oxo-1-phenylpentyl)sulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acidIC5031900.0 [1]
(6Ar,8R,9R,10aS,10bR)-8,9-dimethoxy-2,2,8,9-tetramethyl-4,6a,10a,10b-tetrahydro-[1,4]dioxino[2,3-h][1,3]benzodioxin-6-oneIC50100000.0 [1]
[(3S,4R,5R)-3-Decoxy-4,5-dihydroxy-6-oxocyclohexen-1-yl]methyl acetateIC5037800.0 [1]
[(3R,4S,5R)-3,4,5-Trihydroxy-6-oxocyclohexen-1-yl]methyl acetateIC50100000.0 [1]
(2R,3R,4Ar,8R,8aS)-8-hydroxy-7-(hydroxymethyl)-2,3-dimethoxy-2,3-dimethyl-8,8a-dihydro-4aH-1,4-benzodioxin-5-oneIC50100000.0 [1]
[(2R,3R,4Ar,8R,8aS)-8-hydroxy-2,3-dimethoxy-2,3-dimethyl-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-7-yl]methyl acetateIC50100000.0 [1]
[(3R,4R,5R)-4,5-Dihydroxy-3-methoxy-6-oxocyclohexen-1-yl]methyl acetateIC50100000.0 [1]
[(3R,4R,5R)-4,5-Dihydroxy-6-oxo-3-phenylmethoxycyclohexen-1-yl]methyl acetateIC50100000.0 [1]
[(2R,3R,4Ar,8R,8aS)-8-hydroxy-2,3-dimethoxy-2,3-dimethyl-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC50100000.0 [1]
[(2R,3R,4Ar,8R,8aS)-2,3,8-trimethoxy-2,3-dimethyl-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC50100000.0 [1]
[(3S,4R,5R)-4,5-Dihydroxy-6-oxo-3-phenylmethoxycyclohexen-1-yl]methyl acetateIC50100000.0 [1]
[(2R,3R,4Ar,8S,8aS)-2,3-dimethoxy-2,3-dimethyl-5-oxo-8-phenylmethoxy-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC50100000.0 [1]
[(2R,3R,4Ar,8S,8aS)-2,3-dimethoxy-2,3-dimethyl-8-(naphthalen-2-ylmethoxy)-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC5077600.0 [1]
[(2R,3R,4Ar,8S,8aS)-2,3-dimethoxy-2,3-dimethyl-8-(3-methylbut-2-enoxy)-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC5096300.0 [1]
[(2R,3R,4Ar,8S,8aS)-8-hexoxy-2,3-dimethoxy-2,3-dimethyl-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC5093000.0 [1]
[(2R,3R,4Ar,8S,8aS)-8-[(2E)-3,7-dimethylocta-2,6-dienoxy]-2,3-dimethoxy-2,3-dimethyl-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC50178600.0 [1]
[(2R,3R,4Ar,8S,8aS)-2,3-dimethoxy-2,3-dimethyl-5-oxo-8-[(E)-3-phenylprop-2-enoxy]-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC5094200.0 [1]
[(2R,3R,4Ar,8S,8aS)-2,3-dimethoxy-2,3-dimethyl-5-oxo-8-[(4-phenylphenyl)methoxy]-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC5066300.0 [1]
[(2R,3R,4Ar,8S,8aS)-8-decoxy-2,3-dimethoxy-2,3-dimethyl-5-oxo-8,8a-dihydro-4aH-1,4-benzodioxin-6-yl]methyl acetateIC5033100.0 [1]
Items per page: 1 - 10 of 33
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References

This online tool may be cited as follows

MLA

"Quest Database™ Glutathione S-transferase A2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/glutathione-s-transferase-a2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Glutathione S-transferase A2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutathione-s-transferase-a2-inhibitors-ic50-ki.
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