Glutathione S-transferase A1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	(2-Hydroxyphenyl)-(2-hydroxy-5-phenylphenyl)methanone	IC50	1770.0 [1]
	(2-Hydroxyphenyl)-(2-hydroxy-5-phenylphenyl)methanone	Ki	1470.0 [1]
	(5-Bromo-2-hydroxyphenyl)-(2-hydroxyphenyl)methanone	IC50	240.0 [1]
	(5-Bromo-2-hydroxyphenyl)-(2-hydroxyphenyl)methanone	Ki	360.0 [1]
	N-[Bis(2-hydroxyphenyl)methylideneamino]benzamide	IC50	330.0 [1]
	N-[Bis(2-hydroxyphenyl)methylideneamino]benzamide	Ki	380.0 [1]
	N-[(Z)-[(5-Bromo-2-hydroxyphenyl)-(2-hydroxyphenyl)methylidene]amino]acetamide	IC50	180.0 [1]
	N-[(Z)-[(5-Bromo-2-hydroxyphenyl)-(2-hydroxyphenyl)methylidene]amino]acetamide	Ki	1750.0 [1]
	(4S)-5-[[(2S)-5-Amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-4-amino-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-(benzenesulfonamido)-5-oxopentanoic acid	Ki	1700.0 [1], 8100.0 [2]
	(4S)-5-[[(2S)-5-Amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-4-amino-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-(benzenesulfonamido)-5-oxopentanoic acid	Ki	1700.0 [1], 8100.0 [2]
	(4S)-5-[[(2S)-5-Amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-4-amino-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-(benzenesulfonamido)-5-oxopentanoic acid	Ki	1700.0 [1], 8100.0 [2]
	Ethacrynic acid	IC50	5000.0 [1]
	2-Amino-5-((1-((carboxymethyl)amino)-3-(hexylthio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid	Ki	840.0 [1]
	2-Amino-5-[[1-(2-carboxyethylamino)-3-[(4-methylphenyl)methylsulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Ki	43000.0 [1]
	2-Amino-5-[[3-benzylsulfanyl-1-[[carboxy(phenyl)methyl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Ki	24300.0 [1]
	2-Amino-4-[1-(2-carboxy-ethylcarbamoyl)-2-hexylsulfanyl-ethylcarbamoyl]-butyric acid	Ki	43000.0 [1]
	2-Amino-5-[[1-[[carboxy(phenyl)methyl]amino]-3-hexylsulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Ki	5800.0 [1]
	2-Amino-5-[[1-[[carboxy(phenyl)methyl]amino]-3-[(4-chlorophenyl)methylsulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid	Ki	14700.0 [1]
	2-Amino-4-[2-benzylsulfanyl-1-(2-carboxy-ethylcarbamoyl)-ethylcarbamoyl]-butyric acid	Ki	360000.0 [1]
	3-[[4-[[2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]butanoylamino]methyl]benzamide	IC50	13850.0 [1]
	3,5-Bis((2-(2,3-dichloro-4-(2-methylenebutanoyl)phenoxy)acetamido)methyl)benzamide	IC50	32.7 [1]
	3,5-Bis[[[2-[[2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]acetyl]amino]methyl]benzamide	IC50	24.0 [1]
	3-[[3-[[2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]propanoylamino]methyl]-5-[[3-[[2-[2,3-dichloro-4-(2-methylprop-2-enoyl)phenoxy]acetyl]amino]propanoylamino]methyl]benzamide	IC50	13.7 [1]
	3-[[4-[[2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]butanoylamino]methyl]-5-[[4-[[2-[2,3-dichloro-4-(2-methylprop-2-enoyl)phenoxy]acetyl]amino]butanoylamino]methyl]benzamide	IC50	14.3 [1]
	3-[[6-[[2-[2,3-Dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]hexanoylamino]methyl]-5-[[6-[[2-[2,3-dichloro-4-(2-methylprop-2-enoyl)phenoxy]acetyl]amino]hexanoylamino]methyl]benzamide	IC50	39.3 [1]
	3-[[8-[[2-[2,3-Dichloro-4-(1-hydroxy-2-methylidenebutyl)phenoxy]acetyl]amino]octanoylamino]methyl]-5-[[9-[[2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]nonanoylamino]methyl]benzamide	IC50	52.1 [1]
	3-[[4-[4-[4-[[2-(4-But-1-en-2-yl-2,3-dichlorophenoxy)acetyl]amino]butanoylamino]butanoylamino]butanoylamino]methyl]-5-[[4-[4-[4-[[2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetyl]amino]butanoylamino]butanoylamino]butanoylamino]methyl]benzamide	IC50	98.9 [1]
	1-Methyl-2-[((2-nitrobenzyl)sulfonyl)]-1H-pyrrole	Ki	135000.0 [1]
	N-[2-[(1-Methylpyrrol-2-yl)sulfonylmethyl]phenyl]-1-(4-nitrophenyl)methanimine	Ki	71000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 29 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Glutathione S-transferase A1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Nov. 2024, https://www.aatbio.com/data-sets/glutathione-s-transferase-a1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 22). Quest Database™ Glutathione S-transferase A1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutathione-s-transferase-a1-inhibitors-ic50-ki.
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