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Glutathione reductase Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
▲
▼
Standard Type
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▼
Standard Values (in nM)
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▼
6-(3-Methyl-1,4-Dioxo-1,4-Dihydronaphthalen-2-Yl)hexanoic AcidIC501800.0 [1], 2600.0 [2], 2700.0 [3], 3200.0 [4]
6-(3-Methyl-1,4-Dioxo-1,4-Dihydronaphthalen-2-Yl)hexanoic AcidKi3700.0 [1]
1,4-Pentadien-3-one, 1-(2-chlorophenyl)-IC505000.0 [1], 18500.0 [2], 190000.0 [3]
Glutamic acidIC5053700.0 [1]
Glutamic acidKi42700.0 [1]
LysineIC5061200.0 [1]
LysineKi54600.0 [1]
NifedipineIC5023400.0 [1]
NifedipineKi17400.0 [1]
Methylene blueIC5016000.0 [1], 16400.0 [2]
MenadioneKi12100.0 [1], 16100.0 [2]
NitrobenzeneIC50546800.0 [1]
NitrobenzeneKi274100.0 [1]
(S)-2-(4-Nitrobenzamido)pentanedioic acidIC50344.0 [1]
(S)-2-(4-Nitrobenzamido)pentanedioic acidKi211.0 [1]
(R)-2-(4-Nitrobenzylamino)-1-butanolIC5013300.0 [1]
(R)-2-(4-Nitrobenzylamino)-1-butanolKi4570.0 [1]
(4-Nitrophenyl) (2S)-6-[(2-chlorophenyl)methoxycarbonylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoateIC5015400.0 [1]
(4-Nitrophenyl) (2S)-6-[(2-chlorophenyl)methoxycarbonylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoateKi4160.0 [1]
QuercetinIC50218000.0 [1]
ChlorhexidineKi192000.0 [1]
CarmustineIC508100.0 [1]
QuinacrineIC501000000.0 [1]
Ellagic acidIC5022800.0 [1]
4-Phenyl-3-furoxancarbonitrileIC5050000.0 [1]
2,6-DibenzylidenecyclohexanoneIC50100000.0 [1]
1-[N'-[3-[7-[3-[[Amino-[[N'-(3,3-diphenylpropyl)carbamimidoyl]amino]methylidene]amino]propylamino]heptylamino]propyl]carbamimidoyl]-2-(3,3-diphenylpropyl)guanidineIC50100000.0 [1]
(2E,6E)-2,6-Bis(pyridin-4-ylmethylene)cyclohexanoneIC50100000.0 [1]
Flavellagic acidIC5026700.0 [1]
3-(Hydroxymethyl)-4-phenyl-1,2,5-oxadiazole 2-oxideIC5050000.0 [1]
2,6-Bis(4-(dimethylamino)benzylidene)cyclohexanoneIC50100000.0 [1]
3-(3-Fluoroanilino)-1-(3-nitrophenyl)-1-propanoneIC50173000.0 [1]
2,5-Bis(4-(dimethylamino)benzylidene)cyclopentanoneIC50100000.0 [1]
1-(4-Chlorophenyl)-3-morpholin-4-ylpropan-1-oneIC50212000.0 [1]
3-Anilino-1-(3-nitrophenyl)-1-propanoneIC5058000.0 [1]
3-Formyl-4-phenyl-1,2,5-oxadiazole 2-oxideIC5035200.0 [1]
10-(4-Chlorophenyl)-3-methylbenzo[g]pteridine-2,4(3h,10h)-dioneIC501000.0 [1]
2,5-DibenzylidenecyclopentanoneIC50100000.0 [1]
Methyl (6-bromo-2-methyl-4-phenylquinazolin-3(4H)-yl)acetateIC50100000.0 [1]
5-(3-Methyl-1,4-dioxonaphthalen-2-yl)pentanoic acidIC502700.0 [1]
10-(3,5-Dichlorophenyl)-3-methylbenzo[g]pteridine-2,4-dioneIC501000.0 [1]
1-(3,4-Dichlorophenyl)-2-[3-[2-(dimethylamino)ethyl]-2-iminobenzimidazol-1-yl]ethanolIC50100000.0 [1]
4-((Dimethylamino)methyl)-2,6-diisopropylphenolIC5079300.0 [1]
4-Phenyl-3-furoxancarboxamideIC5050000.0 [1]
(2E,5E)-2,5-Bis(pyridin-4-ylmethylene)cyclopentanoneIC50100000.0 [1]
5-(8-Hydroxy-3-methyl-1,4-dioxonaphthalen-2-yl)pentanoic acidIC501000.0 [1]
6-(8-Hydroxy-3-methyl-1,4-dioxonaphthalen-2-yl)hexanoic acidIC50750.0 [1]
[(1S,2S)-2-Hydroxycyclohexyl] nitrateKi43700.0 [1]
N'-(2-Naphthalen-2-ylacetyl)-5-nitrofuran-2-carbohydrazideIC504.1 [1]
3-(2-Chlorophenothiazin-10-yl)propyl-[(4-chlorophenyl)methyl]-dimethyl-ammoniumKi2200000.0 [1]
3-Methyl-4-phenylfurazan 2-oxideIC5050000.0 [1]
3-Methyl-10-phenyl-10H-benzo[g]pteridine-2,4-dioneIC502000.0 [1]
10-[4-Chlorophenyl]benzo[g]pteridine-2,4(3H,10H)-dioneIC501000.0 [1]
3-Methyl-10-(3-trifluoromethyl-phenyl)-10H-benzo[g]pteridine-2,4-dioneIC501000.0 [1]
1-(3,4-Dichlorophenyl)-3-(dimethylamino)propan-1-one hydrochlorideIC5064800.0 [1]
1-(3,4-Dichlorophenyl)-2-[2-imino-3-(2-piperidin-1-ylethyl)-2,3-dihydro-1H-benzimidazol-1-yl]ethanolIC50100000.0 [1]
10-[3,5-Bis(trifluoromethyl)phenyl]-3-methyl-3,10-dihydrobenzo[g]pteridine-2,4-dioneIC505000.0 [1]
(E)-3-(3,4-Dihydroxyphenyl)-N-[3-[4-[3-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]propylamino]butylamino]propyl]prop-2-enamideKi10000000.0 [1]
[(2R,7R)-7-Hydroxy-2-bicyclo[2.2.1]heptanyl] nitrateKi11700.0 [1]
[(1S,4Z,8S)-8-Hydroxycyclooct-4-en-1-yl] nitrateKi44300.0 [1]
[(1S,6S)-6-Hydroxycyclohex-3-en-1-yl] nitrateKi35100.0 [1]
trans-(R(S))-2-Hydroxy-1-phenylethyl nitrateKi25600.0 [1]
trans-(1S(R),2S(R))-2-Hydroxycyclooctyl nitrateKi21900.0 [1]
3-(Dimethylamino)-1-(3-nitrophenyl)propan-1-one hydrochlorideIC5020300.0 [1]
[(2S,7R)-7-Hydroxy-2-bicyclo[2.2.1]heptanyl] nitrateKi13100.0 [1]
[(1R,2R,5S,6S)-5-Bromo-9-oxabicyclo[4.2.1]nonan-2-yl] nitrateKi21500.0 [1]
2,6-Bis-(4-methyl-benzylidene)-cyclohexanoneIC50100000.0 [1]
3-(2,3-Dimethylphenylamino)-1-(3-nitrophenyl)propan-1-oneIC5086300.0 [1]
1-Methyl-4-(3-methyl-2,4-dioxo-3,4-dihydro-2H-benzo[g]pteridin-10-yl)-pyridiniumIC5040000.0 [1]
1-[3-(2-Methoxy-6-chloro-9-acridinylamino)propyl]-3-benzylureaIC5044700.0 [1]
1-[4-(2-Methoxy-6-chloro-9-acridinylamino)butyl]-3-benzylureaIC5055800.0 [1]
10-(Pentafluorophenyl)benzo[g]pteridine-2,4(3H,10H)-dioneIC503500.0 [1]
2,4-Dioxo-10-[4-chlorophenyl]-2,3,4,10-tetrahydrobenzo[g]pteridine-3-acetic acid ethyl esterIC5018000.0 [1]
2,3,4,10-Tetrahydro-10-(3,5-dichlorophenyl)-2,4-dioxobenzo[g]pteridine-3-acetic acidIC5014000.0 [1]
8-Azido-10-(4-chloro-phenyl)-3-methyl-10H-benzo[g]pteridine-2,4-dioneIC502500.0 [1]
2,3,4,10-Tetrahydro-10-(4-chlorophenyl)-2,4-dioxobenzo[g]pteridine-3-acetic acidIC5012000.0 [1]
2,3-Dihydro-3-oxo-5H-indeno[1,2-c]pyridazine-4-carboxylic acidIC5012300.0 [1]
3-(2-Chlorophenothiazin-10-yl)propyl-(cyclohexylmethyl)-dimethylazaniumKi2000000.0 [1]
2,3,5,6-Tetrahydro-3-oxobenzo[h]cinnoline-4-carboxylic acidIC5018900.0 [1]
N-(2-Cyanoethyl)-5-(3-methyl-1,4-dioxonaphthalen-2-yl)pentanamideIC5022700.0 [1]
3-[5-[4-(3-Methyl-1,4-dioxonaphthalen-2-yl)butyl]tetrazol-1-yl]propanenitrileIC5027000.0 [1]
Coruleoellagic AcidIC507600.0 [1]
4-(4-Hydroxyphenyl)furoxan-3-carbonitrileIC5050000.0 [1]
3-Methyl-10-(naphthalen-1-yl)benzo[g]pteridine-2,4(3H,10H)-dioneIC502000.0 [1]
10-[3,5-Dichlorophenyl]benzo[g]pteridine-2,4(3H,10H)-dioneIC501000.0 [1]
10-(3-Trifluoromethyl-phenyl)-10H-benzo[g]pteridine-2,4-dioneIC501000.0 [1]
10-(3,5-Bis-trifluoromethyl-phenyl)-10H-benzo[g]pteridine-2,4-dioneIC503500.0 [1]
Ethyl 2-[10-(3,5-dichlorophenyl)-2,4-dioxobenzo[g]pteridin-3-yl]acetateIC507000.0 [1]
Ethyl 2-[2,4-dioxo-10-[3-(trifluoromethyl)phenyl]benzo[g]pteridin-3-yl]acetateIC508000.0 [1]
Ethyl 2-[10-[3,5-bis(trifluoromethyl)phenyl]-2,4-dioxobenzo[g]pteridin-3-yl]acetateIC50100000.0 [1]
2,3,4,10-Tetrahydro-10-[3,5-bis(trifluoromethyl)phenyl]-2,4-dioxobenzo[g]pteridine-3-acetic acidIC5025000.0 [1]
3-Methyl-10-pyridin-4-yl-10H-benzo[g]pteridine-2,4-dioneIC503000.0 [1]
3-Methyl-10-pyridin-3-yl-10H-benzo[g]pteridine-2,4-dioneIC508000.0 [1]
10-(4-Chloro-phenyl)-8-fluoro-3-methyl-10H-benzo[g]pteridine-2,4-dioneIC501000.0 [1]
2-Benzyl-1-[3-[7-[3-[(N'-benzylcarbamimidoyl)amino]propylamino]heptylamino]propyl]guanidineIC50100000.0 [1]
2-[3-[4-[3-[[Amino-(3,3-diphenylpropylamino)methylidene]amino]propylamino]butylamino]propyl]-1-(3,3-diphenylpropyl)guanidineIC50100000.0 [1]
2-(2,2-Diphenylethyl)-1-[3-[4-[3-[[N'-(2,2-diphenylethyl)carbamimidoyl]amino]propylamino]butylamino]propyl]guanidineIC50100000.0 [1]
1-[N'-[3-[3-[3-[[Amino-[[N'-(2,2-diphenylethyl)carbamimidoyl]amino]methylidene]amino]propylamino]propylamino]propyl]carbamimidoyl]-2-(2,2-diphenylethyl)guanidineIC50100000.0 [1]
1-[N'-[3-[7-[3-[[Amino-[[N'-(2,2-diphenylethyl)carbamimidoyl]amino]methylidene]amino]propylamino]heptylamino]propyl]carbamimidoyl]-2-(2,2-diphenylethyl)guanidineIC50100000.0 [1]
1-[N'-[3-[4-[3-[[Amino-[[N'-(2,2-diphenylethyl)carbamimidoyl]amino]methylidene]amino]propylamino]butylamino]propyl]carbamimidoyl]-2-(2,2-diphenylethyl)guanidineIC50100000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Glutathione reductase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/glutathione-reductase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Glutathione reductase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutathione-reductase-inhibitors-ic50-ki.
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