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Glutaminyl-peptide cyclotransferase-like protein Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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5-(5-((3,4-Dimethoxyphenylthio)methyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC5080.0 [1]
5-[1-(3-Methoxyphenethyl)-1H-1,2,3-triazole-4-yl]-1H-benzoimidazoleIC50550.0 [1]
5-[1-(4-Methoxyphenethyl)-1H-1,2,3-triazole-4-yl]-1H-benzoimidazoleIC50290.0 [1]
5-[1-(3,4-Dimethoxyphenethyl)-1H-1,2,3-triazole-4-yl]-1H-benzoimidazoleIC50470.0 [1]
5-(1-Phenethyl-1H-1,2,3-triazole-4-yl)-1H-benzoimidazoleIC50570.0 [1]
5-(5-(3,4-Dimethoxyphenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50400.0 [1]
5-(5-(2,4-Difluorophenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50830.0 [1]
2-(3H-Benzimidazol-5-yl)-5-[2-(1,3-benzodioxol-5-yl)ethyl]-1,3,4-thiadiazoleIC50590.0 [1]
5-(5-((3,4-Dimethoxyphenylsulfonyl)methyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50410.0 [1]
5-(5-Phenethyl-1,3,4-thiadiazole-2-yl)-1H-benzoimidazoleIC50640.0 [1]
5-(5-(2,3-Dimethoxyphenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50360.0 [1]
Glutaminyl Cyclase Inhibitor 3IC50502.0 [1]
(E)-1-N'-(2,4-Dimethoxyphenyl)-1-N-[3-(5-methylimidazol-1-yl)propyl]-2-nitroethene-1,1-diamineIC50530.0 [1]
(E)-1-N-[3-(5-Methylimidazol-1-yl)propyl]-2-nitro-1-N'-(3,4,5-trimethoxyphenyl)ethene-1,1-diamineIC50620.0 [1]
(E)-1-N'-(3,4-Dimethoxyphenyl)-1-N-[3-(5-methylimidazol-1-yl)propyl]-2-nitroethene-1,1-diamineIC50730.0 [1]
(E)-1-N'-Cyclohexyl-1-N-[4-(5-methylimidazol-1-yl)butyl]-2-nitroethene-1,1-diamineIC50580.0 [1]
(E)-1-N'-(1,3-Benzodioxol-5-yl)-1-N-[3-(5-methylimidazol-1-yl)propyl]-2-nitroethene-1,1-diamineIC50340.0 [1]
(E)-1-N'-(3,4-Dimethoxyphenyl)-1-N-[3-(4-methylimidazol-1-yl)propyl]-2-nitroethene-1,1-diamineIC508730.0 [1]
(E)-1-N-[3-(4-Methylimidazol-1-yl)propyl]-2-nitro-1-N'-(3,4,5-trimethoxyphenyl)ethene-1,1-diamineIC509680.0 [1]
(E)-1-N'-(2,4-Dimethoxyphenyl)-1-N-[3-(4-methylimidazol-1-yl)propyl]-2-nitroethene-1,1-diamineIC509450.0 [1]
(E)-1-N'-(1,3-Benzodioxol-5-yl)-1-N-[3-(4-methylimidazol-1-yl)propyl]-2-nitroethene-1,1-diamineIC5010400.0 [1]
6-[4-[(3-Chloro-4-methoxyphenyl)methyl]-1,2,4-triazol-3-yl]-1H-benzimidazoleIC50850.0 [1]
6-[1-(Phenylsulfanylmethyl)triazol-4-yl]-1H-benzimidazoleIC50570.0 [1]
5-(5-(3,4,5-Trimethoxyphenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50490.0 [1]
5-(5-(3,4-Difluorophenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50720.0 [1]
5-(5-(3-Chloro-4-methoxyphenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50680.0 [1]
5-(5-(3-Chloro-4-methoxyphenethyl)-1,3,4-oxadiazol-2-yl)-1H-benzo[d]imidazoleIC50800.0 [1]
5-(5-(4-(Methylthio)phenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50760.0 [1]
5-(4-(2-Chlorobenzyl)-4H-1,2,4-triazol-3-yl)-1H-benzo[d]imidazoleIC50760.0 [1]
5-(5-(3-Methoxyphenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50450.0 [1]
2-(3H-Benzimidazol-5-yl)-5-[2-(3-fluorophenyl)ethyl]-1,3,4-thiadiazoleIC50560.0 [1]
6-[4-[(4-Phenoxyphenyl)methyl]-1,2,4-triazol-3-yl]-1H-benzimidazoleIC50480.0 [1]
5-(4-(4-Methoxybenzyl)-4H-1,2,4-triazol-3-yl)-1H-benzo[d]imidazoleIC50640.0 [1]
2-(3H-Benzimidazol-5-yl)-5-[2-(2-chloro-3-methoxyphenyl)ethyl]-1,3,4-thiadiazoleIC50220.0 [1]
5-(5-((Phenylthio)methyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50530.0 [1]
5-(5-(2,5-Dimethoxyphenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50480.0 [1]
5-(5-(2-Methoxyphenethyl)-1,3,4-thiadiazol-2-yl)-1H-benzo[d]imidazoleIC50760.0 [1]
(E)-1-N'-(4-Chlorophenyl)-1-N-[3-(4-methylimidazol-1-yl)propyl]-2-nitroethene-1,1-diamineIC508600.0 [1]
(E)-1-N-[3-(4-Methylimidazol-1-yl)propyl]-1-N'-naphthalen-1-yl-2-nitroethene-1,1-diamineIC507460.0 [1]
6-[4-[(2,3-Dichlorophenyl)methyl]-1,2,4-triazol-3-yl]-1H-benzimidazoleIC50520.0 [1]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N'-[3-(4-methylimidazol-1-yl)propyl]-2-nitroethanimidamideIC508790.0 [1]
N-(1-(3-(5-Methyl-1H-imidazol-1-yl)propylamino)-2-nitrovinyl)cyclohexanamineIC50340.0 [1]
N-(1-(3-(5-Methyl-1H-imidazol-1-yl)propylamino)-2-nitrovinyl)naphthalen-1-amineIC50230.0 [1]
N-(1-(3-(5-Methyl-1H-imidazol-1-yl)propylamino)-2-nitrovinyl)-4-(trifluoromethyl)benzenamineIC50430.0 [1]
N-(4-Chlorophenyl)-N'-[3-(5-methylimidazol-1-yl)propyl]-2-nitroethanimidamideIC50320.0 [1]
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-N'-[3-(5-methylimidazol-1-yl)propyl]-2-nitroethanimidamideIC50460.0 [1]
Items per page: 1 - 10 of 46
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References

This online tool may be cited as follows

MLA

"Quest Database™ Glutaminyl-peptide cyclotransferase-like protein Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/glutaminyl-peptide-cyclotransferase-like-protein-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Glutaminyl-peptide cyclotransferase-like protein Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutaminyl-peptide-cyclotransferase-like-protein-inhibitors-ic50-ki.
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