| N,N'-[Sulfanediylbis(Ethane-2,1-Diyl-1,3,4-Thiadiazole-5,2-Diyl)]bis(2-Phenylacetamide) | IC50 | 200.0 [1] |
| Telaglenastat | IC50 | 5.0 [1], 60.0 [2], 180.0 [3], 2200.0 [4] |
| N-[5-[2-[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 2700.0 [1], 15000.0 [2] |
| N-[5-[2-[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | Ki | 2000.0 [1] |
| (2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-(1,2,4-triazin-3-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 3.9 [1], 62.8 [2] |
| (2R)-2-Methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide | IC50 | 0.21 [1], 43.36 [2] |
| (2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 0.39 [1], 29.0 [2] |
| (2S)-2-Methoxy-2-(4-methoxyphenyl)-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 0.4 [1], 31.0 [2] |
| (2R)-2-(4-Fluoro-3-methoxyphenyl)-2-methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 4.99 [1], 70.69 [2] |
| (2S)-2-(4-Fluorophenyl)-2-methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-3-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 175.1 [1], 2187.0 [2] |
| (5Z)-5-{[1-(4-Bromophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylidene}-4-hydroxy-1,3-thiazol-2(5H)-one | IC50 | 3097.0 [1], 5373.0 [2] |
| 5-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-3-ethylphenyl]benzonitrile | IC50 | 59.0 [1], 92.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-methoxyphenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 66.0 [1], 177.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 48.0 [1], 148.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 243.0 [1], 355.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 39.0 [1], 87.0 [2] |
| (5Z)-5-[[2-Chloro-4-[4-[3-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 57.0 [1], 255.0 [2] |
| (5Z)-5-[[1-(4-Bromophenyl)-2,5-diphenylpyrrol-3-yl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 4896.0 [1], 8762.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 56.0 [1], 217.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 45.0 [1], 151.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-hydroxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 247.0 [1], 760.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 49.0 [1], 50.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 35.0 [1], 53.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 102.0 [1], 381.0 [2] |
| (5Z)-5-[[1-(4-Bromophenyl)-2,5-dithiophen-2-ylpyrrol-3-yl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 754.0 [1], 1275.0 [2] |
| (5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dione | IC50 | 54.0 [1], 391.0 [2] |
| 2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 160.0 [1], 1800.0 [2] |
| 2-Phenyl-N-[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 70.0 [1], 110.0 [2] |
| 2-Phenyl-N-[5-[4-[5-[(2-pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 70.0 [1], 83.0 [2] |
| 3-Hydroxy-N-[5-[4-[5-[(3-hydroxy-2-phenylpropanoyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylpropanamide | IC50 | 40.0 [1], 220.0 [2] |
| (2S)-2-Hydroxy-N-[5-[4-[5-[[(2S)-2-hydroxy-2-phenylacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 140.0 [1], 380.0 [2] |
| (2S)-2-Amino-N-[5-[4-[5-[[(2S)-2-amino-2-phenylacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 2800.0 [1], 3100.0 [2] |
| Ethyl N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]carbamate | IC50 | 810.0 [1] |
| Tert-butyl 4-[[3-[2-[[5-[2-[[5-[[2-[3-[[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]methyl]phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]methylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl]methyl]piperazine-1-carboxylate | IC50 | 150.0 [1], 2200.0 [2] |
| 2-(3-Bromophenyl)-N-[5-[4-[5-[[2-(3-bromophenyl)-2-hydroxyacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-hydroxyacetamide | IC50 | 40.0 [1], 670.0 [2] |
| 2-Phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]acetamide | IC50 | 10.0 [1], 57.0 [2] |
| 2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-oxadiazol-2-yl]butyl]-1,3,4-oxadiazol-2-yl]acetamide | IC50 | 20000.0 [1] |
| 2-(3-Chlorophenyl)-N-[5-[4-[5-[[2-(3-chlorophenyl)-2-hydroxyacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-hydroxyacetamide | IC50 | 31.0 [1], 520.0 [2] |
| 2-Hydroxy-2-(3-methoxyphenyl)-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 7.0 [1], 180.0 [2] |
| 2-(3-Chlorophenyl)-2-hydroxy-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 6.0 [1], 180.0 [2] |
| 2-[3-(Aminomethyl)phenyl]-N-[5-[4-[5-[[2-[3-(aminomethyl)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 170.0 [1], 660.0 [2] |
| N-[6-[4-[5-[[2-[3-(Aminomethyl)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-phenylacetamide | IC50 | 13.0 [1], 130.0 [2] |
| 2-(3-Chlorophenyl)-2-hydroxy-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 24.0 [1], 130.0 [2] |
| 2-Hydroxy-2-phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]acetamide | IC50 | 30.0 [1], 150.0 [2] |
| N-[5-[4-[6-[[2-[3-(Aminomethyl)phenyl]acetyl]amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 9.0 [1], 110.0 [2] |
| Tert-butyl N-[[3-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamate | IC50 | 5.0 [1], 380.0 [2] |
| Tert-butyl N-[[3-[2-oxo-2-[[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamate | IC50 | 5.0 [1], 160.0 [2] |
| Ethyl N-[[3-[2-oxo-2-[[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamate | IC50 | 3.0 [1], 99.0 [2] |
| Ethyl N-[[3-[2-oxo-2-[[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]amino]ethyl]phenyl]methyl]carbamate | IC50 | 3.0 [1], 81.0 [2] |
| Tert-butyl N-[[3-[2-[[5-[4-[5-[[2-[3-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl]methyl]carbamate | IC50 | 11.0 [1], 4600.0 [2] |
| 2-(3-Bromophenyl)-N-[5-[2-[2-[5-[[2-(3-bromophenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 5000.0 [1], 7400.0 [2] |
| N-[5-[4-[5-[[2-(4-Hydroxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 70.0 [1] |
| N-[5-[4-[5-[[2-(4-Aminophenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 2300.0 [1] |
| 2-Phenyl-N-[5-[[(3R)-1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 30.0 [1] |
| 2-Phenyl-N-[5-[[(3S)-1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 70.0 [1] |
| 2-Phenyl-N-[5-[(3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 40.0 [1] |
| 2-Phenyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 30.0 [1] |
| 2-Phenyl-N-[6-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]oxypiperidin-1-yl]pyridazin-3-yl]acetamide | IC50 | 98.0 [1] |
| N-[5-[1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 207.0 [1] |
| 2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 5000.0 [1] |
| 2-Phenyl-N-[5-[(3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 30.0 [1] |
| 2-Phenyl-N-[5-[(3R)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 36.0 [1] |
| 2-Phenyl-N-[6-[1-[6-[(2-phenylacetyl)amino]pyridin-3-yl]piperidin-4-yl]oxypyridin-3-yl]acetamide | IC50 | 5000.0 [1] |
| 2-Phenyl-N-[5-[3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]azetidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 60.0 [1] |
| 2-Cyclopropyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 30.0 [1] |
| 2-Phenyl-N-[5-[3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 490.0 [1] |
| N-[5-[4-[(5-Acetamido-1,3,4-thiadiazol-2-yl)oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 1005.0 [1] |
| N-[5-[(3S)-1-(5-Amino-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 9700.0 [1] |
| N-[5-[(3R)-1-(5-Amino-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 1400.0 [1] |
| 2-Phenyl-N-[5-[(3R)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 790.0 [1] |
| N-[5-[[1-(5-Amino-1,3,4-thiadiazol-2-yl)azetidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 227.0 [1] |
| 2-Phenyl-N-[5-[[1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperidin-4-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 29.0 [1] |
| 2-Phenyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 190.0 [1] |
| 2-Cyclopropyl-N-[5-[4-[[5-[(2-cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 157.0 [1] |
| N-[5-[[(3S)-1-(5-Acetamido-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 7700.0 [1] |
| 2-Phenyl-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridin-3-yl]oxypiperidin-1-yl]pyridin-2-yl]acetamide | IC50 | 5000.0 [1] |
| N-[5-[[(3R)-1-(5-Acetamido-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 720.0 [1] |
| 2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperazin-1-yl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 3070.0 [1] |
| 2-Phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]pyridin-2-yl]oxypiperidin-1-yl]pyridin-3-yl]acetamide | IC50 | 5000.0 [1] |
| 2-Phenyl-N-[6-[1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperidin-4-yl]oxypyridazin-3-yl]acetamide | IC50 | 36.0 [1] |
| N-[5-[1-(5-Amino-1,3,4-thiadiazol-2-yl)azetidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 540.0 [1] |
| 2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]pyrazin-2-yl]oxypiperidin-1-yl]pyrazin-2-yl]acetamide | IC50 | 5000.0 [1] |
| 2-Phenyl-N-[5-[[(1S,3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]cyclopentyl]amino]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 50.0 [1] |
| 2-Phenyl-N-[5-[4-[5-[[2-(4-phenylmethoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 25000.0 [1] |
| N-[5-[4-[5-[[2-[4-(Dimethylamino)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 3000.0 [1] |
| N-[5-[4-[5-[[2-(3-Hydroxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 120.0 [1] |
| N-[5-[4-[5-[[2-(5-Bromopyridin-2-yl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 170.0 [1] |
| [4-[2-Oxo-2-[[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetate | IC50 | 120.0 [1] |
| 2-(4-Hydroxyphenyl)-N-[5-[4-[5-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 510.0 [1] |
| 2-(4-Hydroxyphenyl)-N-[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamide | IC50 | 140.0 [1] |
| N-[5-[4-[5-[[2-(4-Methoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 210.0 [1] |
| N-[5-[4-[5-[[2-(4-Phenoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamide | IC50 | 380.0 [1] |
| 4-[2-Oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoic acid | IC50 | 110.0 [1] |
| [4-[2-[[5-[4-[5-[[2-(4-Acetyloxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl] acetate | IC50 | 1200.0 [1] |
| [4-[2-Oxo-2-[[5-[4-[5-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetate | IC50 | 2000.0 [1] |
| [4-[2-Oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetate | IC50 | 540.0 [1] |
| Methyl 4-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoate | IC50 | 13000.0 [1] |
| Tert-butyl N-[4-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]carbamate | IC50 | 450.0 [1] |
| (3S,4S,6R)-6-[(1S)-1-[(1S,3R,8S,9S,10R,13S,14S,17R)-1,3-Dihydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-3,4-dihydroxy-3,4-dimethyloxan-2-one | IC50 | 100000.0 [1] |
| (3S,4S,6R)-3,4-Dihydroxy-6-[(1S)-1-[(1S,3R,8S,9S,10R,13S,14S,17R)-1-hydroxy-10,13-dimethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-3,4-dimethyloxan-2-one | IC50 | 100000.0 [1] |