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Glutaminase kidney isoform, mitochondrial Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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N,N'-[Sulfanediylbis(Ethane-2,1-Diyl-1,3,4-Thiadiazole-5,2-Diyl)]bis(2-Phenylacetamide)IC50200.0 [1]
TelaglenastatIC505.0 [1], 60.0 [2], 180.0 [3], 2200.0 [4]
N-[5-[2-[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC502700.0 [1], 15000.0 [2]
N-[5-[2-[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideKi2000.0 [1]
(2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-(1,2,4-triazin-3-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC503.9 [1], 62.8 [2]
(2R)-2-Methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-[3-(trifluoromethoxy)phenyl]acetamideIC500.21 [1], 43.36 [2]
(2S)-2-Methoxy-2-phenyl-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC500.39 [1], 29.0 [2]
(2S)-2-Methoxy-2-(4-methoxyphenyl)-N-[5-[[(3R)-1-pyridazin-3-ylpyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC500.4 [1], 31.0 [2]
(2R)-2-(4-Fluoro-3-methoxyphenyl)-2-methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-6-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC504.99 [1], 70.69 [2]
(2S)-2-(4-Fluorophenyl)-2-methoxy-N-[5-[[(3R)-1-(1,2,4-triazin-3-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC50175.1 [1], 2187.0 [2]
(5Z)-5-{[1-(4-Bromophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylidene}-4-hydroxy-1,3-thiazol-2(5H)-oneIC503097.0 [1], 5373.0 [2]
5-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-3-ethylphenyl]benzonitrileIC5059.0 [1], 92.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-methoxyphenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5066.0 [1], 177.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5048.0 [1], 148.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC50243.0 [1], 355.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5039.0 [1], 87.0 [2]
(5Z)-5-[[2-Chloro-4-[4-[3-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5057.0 [1], 255.0 [2]
(5Z)-5-[[1-(4-Bromophenyl)-2,5-diphenylpyrrol-3-yl]methylidene]-1,3-thiazolidine-2,4-dioneIC504896.0 [1], 8762.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5056.0 [1], 217.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-diphenylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5045.0 [1], 151.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]-2-hydroxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC50247.0 [1], 760.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5049.0 [1], 50.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]-2-methoxyphenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5035.0 [1], 53.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dimethylpyrrol-1-yl]phenyl]phenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC50102.0 [1], 381.0 [2]
(5Z)-5-[[1-(4-Bromophenyl)-2,5-dithiophen-2-ylpyrrol-3-yl]methylidene]-1,3-thiazolidine-2,4-dioneIC50754.0 [1], 1275.0 [2]
(5Z)-5-[[4-[4-[3-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]-2,5-dithiophen-2-ylpyrrol-1-yl]phenyl]-2-ethylphenyl]methylidene]-1,3-thiazolidine-2,4-dioneIC5054.0 [1], 391.0 [2]
2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC50160.0 [1], 1800.0 [2]
2-Phenyl-N-[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC5070.0 [1], 110.0 [2]
2-Phenyl-N-[5-[4-[5-[(2-pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC5070.0 [1], 83.0 [2]
3-Hydroxy-N-[5-[4-[5-[(3-hydroxy-2-phenylpropanoyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylpropanamideIC5040.0 [1], 220.0 [2]
(2S)-2-Hydroxy-N-[5-[4-[5-[[(2S)-2-hydroxy-2-phenylacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50140.0 [1], 380.0 [2]
(2S)-2-Amino-N-[5-[4-[5-[[(2S)-2-amino-2-phenylacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC502800.0 [1], 3100.0 [2]
Ethyl N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]carbamateIC50810.0 [1]
Tert-butyl 4-[[3-[2-[[5-[2-[[5-[[2-[3-[[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]methyl]phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]methylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl]methyl]piperazine-1-carboxylateIC50150.0 [1], 2200.0 [2]
2-(3-Bromophenyl)-N-[5-[4-[5-[[2-(3-bromophenyl)-2-hydroxyacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-hydroxyacetamideIC5040.0 [1], 670.0 [2]
2-Phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]acetamideIC5010.0 [1], 57.0 [2]
2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-oxadiazol-2-yl]butyl]-1,3,4-oxadiazol-2-yl]acetamideIC5020000.0 [1]
2-(3-Chlorophenyl)-N-[5-[4-[5-[[2-(3-chlorophenyl)-2-hydroxyacetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-hydroxyacetamideIC5031.0 [1], 520.0 [2]
2-Hydroxy-2-(3-methoxyphenyl)-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC507.0 [1], 180.0 [2]
2-(3-Chlorophenyl)-2-hydroxy-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC506.0 [1], 180.0 [2]
2-[3-(Aminomethyl)phenyl]-N-[5-[4-[5-[[2-[3-(aminomethyl)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC50170.0 [1], 660.0 [2]
N-[6-[4-[5-[[2-[3-(Aminomethyl)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-phenylacetamideIC5013.0 [1], 130.0 [2]
2-(3-Chlorophenyl)-2-hydroxy-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC5024.0 [1], 130.0 [2]
2-Hydroxy-2-phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]acetamideIC5030.0 [1], 150.0 [2]
N-[5-[4-[6-[[2-[3-(Aminomethyl)phenyl]acetyl]amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC509.0 [1], 110.0 [2]
Tert-butyl N-[[3-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamateIC505.0 [1], 380.0 [2]
Tert-butyl N-[[3-[2-oxo-2-[[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamateIC505.0 [1], 160.0 [2]
Ethyl N-[[3-[2-oxo-2-[[5-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]methyl]carbamateIC503.0 [1], 99.0 [2]
Ethyl N-[[3-[2-oxo-2-[[6-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]amino]ethyl]phenyl]methyl]carbamateIC503.0 [1], 81.0 [2]
Tert-butyl N-[[3-[2-[[5-[4-[5-[[2-[3-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl]methyl]carbamateIC5011.0 [1], 4600.0 [2]
2-(3-Bromophenyl)-N-[5-[2-[2-[5-[[2-(3-bromophenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]ethylsulfanyl]ethyl]-1,3,4-thiadiazol-2-yl]acetamideIC505000.0 [1], 7400.0 [2]
N-[5-[4-[5-[[2-(4-Hydroxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC5070.0 [1]
N-[5-[4-[5-[[2-(4-Aminophenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC502300.0 [1]
2-Phenyl-N-[5-[[(3R)-1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC5030.0 [1]
2-Phenyl-N-[5-[[(3S)-1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC5070.0 [1]
2-Phenyl-N-[5-[(3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC5040.0 [1]
2-Phenyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC5030.0 [1]
2-Phenyl-N-[6-[4-[6-[(2-phenylacetyl)amino]pyridazin-3-yl]oxypiperidin-1-yl]pyridazin-3-yl]acetamideIC5098.0 [1]
N-[5-[1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidin-4-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50207.0 [1]
2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]-1,4-diazepan-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC505000.0 [1]
2-Phenyl-N-[5-[(3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC5030.0 [1]
2-Phenyl-N-[5-[(3R)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC5036.0 [1]
2-Phenyl-N-[6-[1-[6-[(2-phenylacetyl)amino]pyridin-3-yl]piperidin-4-yl]oxypyridin-3-yl]acetamideIC505000.0 [1]
2-Phenyl-N-[5-[3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]azetidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC5060.0 [1]
2-Cyclopropyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC5030.0 [1]
2-Phenyl-N-[5-[3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC50490.0 [1]
N-[5-[4-[(5-Acetamido-1,3,4-thiadiazol-2-yl)oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC501005.0 [1]
N-[5-[(3S)-1-(5-Amino-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC509700.0 [1]
N-[5-[(3R)-1-(5-Amino-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC501400.0 [1]
2-Phenyl-N-[5-[(3R)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC50790.0 [1]
N-[5-[[1-(5-Amino-1,3,4-thiadiazol-2-yl)azetidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50227.0 [1]
2-Phenyl-N-[5-[[1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperidin-4-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC5029.0 [1]
2-Phenyl-N-[5-[4-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxymethyl]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC50190.0 [1]
2-Cyclopropyl-N-[5-[4-[[5-[(2-cyclopropylacetyl)amino]-1,3,4-thiadiazol-2-yl]oxy]piperidin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC50157.0 [1]
N-[5-[[(3S)-1-(5-Acetamido-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC507700.0 [1]
2-Phenyl-N-[5-[4-[6-[(2-phenylacetyl)amino]pyridin-3-yl]oxypiperidin-1-yl]pyridin-2-yl]acetamideIC505000.0 [1]
N-[5-[[(3R)-1-(5-Acetamido-1,3,4-thiadiazol-2-yl)pyrrolidin-3-yl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC50720.0 [1]
2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperazin-1-yl]-1,3,4-thiadiazol-2-yl]acetamideIC503070.0 [1]
2-Phenyl-N-[6-[4-[5-[(2-phenylacetyl)amino]pyridin-2-yl]oxypiperidin-1-yl]pyridin-3-yl]acetamideIC505000.0 [1]
2-Phenyl-N-[6-[1-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]piperidin-4-yl]oxypyridazin-3-yl]acetamideIC5036.0 [1]
N-[5-[1-(5-Amino-1,3,4-thiadiazol-2-yl)azetidin-3-yl]oxy-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50540.0 [1]
2-Phenyl-N-[5-[4-[5-[(2-phenylacetyl)amino]pyrazin-2-yl]oxypiperidin-1-yl]pyrazin-2-yl]acetamideIC505000.0 [1]
2-Phenyl-N-[5-[[(1S,3S)-3-[[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]amino]cyclopentyl]amino]-1,3,4-thiadiazol-2-yl]acetamideIC5050.0 [1]
2-Phenyl-N-[5-[4-[5-[[2-(4-phenylmethoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC5025000.0 [1]
N-[5-[4-[5-[[2-[4-(Dimethylamino)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC503000.0 [1]
N-[5-[4-[5-[[2-(3-Hydroxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50120.0 [1]
N-[5-[4-[5-[[2-(5-Bromopyridin-2-yl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50170.0 [1]
[4-[2-Oxo-2-[[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetateIC50120.0 [1]
2-(4-Hydroxyphenyl)-N-[5-[4-[5-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC50510.0 [1]
2-(4-Hydroxyphenyl)-N-[5-[4-[5-[(2-pyridin-3-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]acetamideIC50140.0 [1]
N-[5-[4-[5-[[2-(4-Methoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50210.0 [1]
N-[5-[4-[5-[[2-(4-Phenoxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]-2-phenylacetamideIC50380.0 [1]
4-[2-Oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoic acidIC50110.0 [1]
[4-[2-[[5-[4-[5-[[2-(4-Acetyloxyphenyl)acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]-2-oxoethyl]phenyl] acetateIC501200.0 [1]
[4-[2-Oxo-2-[[5-[4-[5-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetateIC502000.0 [1]
[4-[2-Oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl] acetateIC50540.0 [1]
Methyl 4-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]benzoateIC5013000.0 [1]
Tert-butyl N-[4-[2-oxo-2-[[5-[4-[5-[(2-phenylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]-1,3,4-thiadiazol-2-yl]amino]ethyl]phenyl]carbamateIC50450.0 [1]
(3S,4S,6R)-6-[(1S)-1-[(1S,3R,8S,9S,10R,13S,14S,17R)-1,3-Dihydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-3,4-dihydroxy-3,4-dimethyloxan-2-oneIC50100000.0 [1]
(3S,4S,6R)-3,4-Dihydroxy-6-[(1S)-1-[(1S,3R,8S,9S,10R,13S,14S,17R)-1-hydroxy-10,13-dimethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-3,4-dimethyloxan-2-oneIC50100000.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ Glutaminase kidney isoform, mitochondrial Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/glutaminase-kidney-isoform-mitochondrial-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Glutaminase kidney isoform, mitochondrial Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutaminase-kidney-isoform-mitochondrial-inhibitors-ic50-ki.
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