Glutamate receptor ionotropic kainate Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline	IC50	8000.0 [1]
	2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline	Ki	2600.0 [1]
	Kainic acid	IC50	77.0 [1]
	alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID	IC50	68000.0 [1]
	6,7-Dinitro-1,4-dihydroquinoxaline-2,3-dione	IC50	2900.0 [1]
	5,7-Dichlorokynurenic acid	IC50	100000.0 [1]
	Tezampanel	IC50	247000.0 [1]
	6-Imidazol-1-yl-7-nitro-1,4-dihydro-quinoxaline-2,3-dione	Ki	4800.0 [1]
	6,7-Dichloro-3-hydroxy-2-quinoxalinecarboxylic acid	IC50	32600.0 [1]
	[(1S)-1-{[(7-Bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl]amino}ethyl]phosphonic acid	IC50	2700.0 [1]
	(3S,4Ar,6S,8aR)-6-(2H-tetrazol-5-yl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	IC50	100000.0 [1]
	2-Amino-3-[3-hydroxy-5-(1-methyl-1H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid	IC50	100000.0 [1]
	(3S,4Ar,6S,8aR)-6-(2H-tetrazol-5-ylmethyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	IC50	100000.0 [1]
	2-Amino-3-[3-oxo-5-(1,3-thiazol-2-yl)-1,2-oxazol-4-yl]propanoic acid	IC50	4900.0 [1]
	2-[4-[4-(3-Methoxyphenyl)piperazin-1-yl]butyl]-4-methyl-1,2,4-triazine-3,5-dione	Ki	10000.0 [1]
	2-Amino-3-[5-(2-methyltetrazol-5-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	IC50	41000.0 [1]
	N-(6,7-Dichloro-3-oxo-3,4-dihydro-quinoxaline-2-carbonyl)-benzenesulfonamide	IC50	19700.0 [1]
	2-[7-[3-[[(4-Nitrophenyl)carbamoylamino]methyl]pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	70.0 [1]
	(3S,4Ar,6R,8aR)-6-(2H-tetrazol-5-yl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	IC50	100000.0 [1]
	2-Amino-3-[5-(1-methylimidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	IC50	74000.0 [1]
	2-Amino-3-[5-(2-methyl-1,2,4-triazol-3-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	IC50	16000.0 [1]
	2-Amino-3-[3-oxo-5-(1H-1,2,4-triazol-5-yl)-1,2-oxazol-4-yl]propanoic acid	IC50	58000.0 [1]
	2-Amino-3-[3-oxo-5-(2H-tetrazol-5-yl)-1,2-oxazol-4-yl]propanoic acid	IC50	100000.0 [1]
	2-Amino-3-[5-(1H-imidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	IC50	100000.0 [1]
	2-Amino-3-[5-(1-methyl-1,2,4-triazol-3-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	IC50	100000.0 [1]
	1-(Carboxymethyl)-6-nitro-7-(1-pyrrolyl)-2,3(1H,4H)-quinoxalinedione	Ki	410.0 [1]
	2,3-Dioxo-6-nitro-7-(3-carboxy-1H-pyrrole-1-yl)-1,2,3,4-tetrahydroquinoxaline-1-acetic acid	Ki	5900.0 [1]
	(3S,4Ar,6R,8aR)-6-[2-(4H-triazol-5-yl)ethyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	IC50	247000.0 [1]
	3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-4H-quinoxalin-1-yl)propanoic acid	Ki	5200.0 [1]
	2-[2,3-Dioxo-7-[3-[(phenylcarbamoylamino)methyl]pyrrol-1-yl]-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	3400.0 [1]
	1-Carboxymethyl-7-(1-pyrrolyl)-6-trifluoromethyl-2,3(1H,4H)-quinoxalinedione	Ki	1500.0 [1]
	2-[7-[3-[[(4-Ethoxycarbonylphenyl)carbamoylamino]methyl]pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	700.0 [1]
	2-[7-[3-[[(3-Ethoxycarbonylphenyl)carbamoylamino]methyl]pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	1200.0 [1]
	3-[[1-[4-(Carboxymethyl)-2,3-dioxo-7-(trifluoromethyl)-1H-quinoxalin-6-yl]pyrrol-3-yl]methylcarbamoylamino]benzoic acid	Ki	6700.0 [1]
	6-(1-Pyrrolyl)-7-nitro-2,3(1H,4H)-quinoxalinedione	Ki	4900.0 [1]
	2-[7-[3-(Benzamidomethyl)pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	3300.0 [1]
	2-[7-[3-(Acetamidomethyl)pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	4800.0 [1]
	2-[7-[3-[(Benzylcarbamoylamino)methyl]pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	1670.0 [1]
	2-[2,3-Dioxo-6-(trifluoromethyl)-7-[3-[[[4-(trifluoromethyl)phenyl]carbamoylamino]methyl]pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid	Ki	110.0 [1]
	2-[6-Nitro-2,3-dioxo-7-[3-[(phenylcarbamoylamino)methyl]pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid	Ki	2600.0 [1]
	1-[[1-(7-Nitro-2,3-dioxo-1,4-dihydroquinoxalin-6-yl)pyrrol-3-yl]methyl]-3-phenylurea	Ki	2790.0 [1]
	1-(7-Nitro-2,3-dioxo-1,4-dihydroquinoxalin-6-yl)pyrrole-3-carboxylic acid	Ki	5000.0 [1]
	Ethyl 3-(6-nitro-2,3-dioxo-7-pyrrol-1-yl-4H-quinoxalin-1-yl)propanoate	Ki	8500.0 [1]
	6,7-Dichloro-N-methylsulfonyl-3-oxo-4H-quinoxaline-2-carboxamide	IC50	103000.0 [1]
	1-[4-(Carboxymethyl)-2,3-dioxo-7-(trifluoromethyl)-1H-quinoxalin-6-yl]pyrrole-3-carboxylic acid	Ki	5700.0 [1]
	4-[[1-[4-(Carboxymethyl)-2,3-dioxo-7-(trifluoromethyl)-1H-quinoxalin-6-yl]pyrrol-3-yl]methylcarbamoylamino]benzoic acid	Ki	3600.0 [1]
	2-[7-[3-[[(4-Bromophenyl)carbamoylamino]methyl]pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	110.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 47 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Glutamate receptor ionotropic kainate Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/glutamate-receptor-ionotropic-kainate-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ Glutamate receptor ionotropic kainate Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutamate-receptor-ionotropic-kainate-inhibitors-ic50-ki.
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