Glutamate receptor ionotropic kainate 5 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Glutamic acid	Ki	701.0 [1], 750.0 [2]
	Kainic acid	Ki	8.0 [1], 80.0 [2], 177.0 [3]
	(2S,4R)-2-Amino-4-[(E)-3-naphthalen-2-ylprop-2-enyl]pentanedioic acid	Ki	10000.0 [1]
	(S)-Ampa	Ki	2144.0 [1]
	Willardiine	Ki	28900.0 [1]
	2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid	Ki	1820.0 [1]
	Iodo-willardiine	Ki	0.24 [1]
	Bromo-willardiine	Ki	9.1 [1]
	(3S,4Ar,6S,8aR)-6-[[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	Ki	8900.0 [1]
	3-(5-Chloro-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)-L-Alanine	Ki	57.1 [1]
	3-(5-Nitro-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)-L-Alanine	Ki	393.0 [1]
	(2S)-2-Amino-4-cyclopentylidenepentanedioic acid	Ki	10000.0 [1]
	CID 10330442	Ki	7500.0 [1]
	(2S)-2-Amino-4-pentan-3-ylidenepentanedioic acid	Ki	21400.0 [1]
	2-[7-[3-[[(4-Nitrophenyl)carbamoylamino]methyl]pyrrol-1-yl]-2,3-dioxo-6-(trifluoromethyl)-4H-quinoxalin-1-yl]acetic acid	Ki	12000.0 [1]
	(2S,4R)-2-Amino-4-[(E)-3-(2-methoxyphenyl)prop-2-enyl]pentanedioic acid	Ki	10000.0 [1]
	(2S,4Z)-2-Amino-4-(2-methylpropylidene)pentanedioic Acid	Ki	82200.0 [1]
	1-(Carboxymethyl)-6-nitro-7-(1-pyrrolyl)-2,3(1H,4H)-quinoxalinedione	Ki	1300.0 [1]
	2-[6-Nitro-2,3-dioxo-7-[3-(piperidin-1-ylmethyl)pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid	Ki	30000.0 [1]
	2-[6-Nitro-2,3-dioxo-7-[3-[(4-phenylpiperidin-1-yl)methyl]pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid	Ki	18000.0 [1]
	[7-(3-Aminomethyl-pyrrol-1-yl)-6-nitro-2,3-dioxo-3,4-dihydro-2H-quinoxalin-1-yl]-acetic acid	Ki	9800.0 [1]
	2,3-Dioxo-6-nitro-7-(3-carboxy-1H-pyrrole-1-yl)-1,2,3,4-tetrahydroquinoxaline-1-acetic acid	Ki	11000.0 [1]
	2-[6-Nitro-2,3-dioxo-7-[3-[(3-phenylpropylamino)methyl]pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid	Ki	20000.0 [1]
	3-(6-Nitro-2,3-dioxo-7-pyrrol-1-yl-4H-quinoxalin-1-yl)propanoic acid	Ki	25000.0 [1]
	3-[7-[3-[[Benzyl(methyl)amino]methyl]pyrrol-1-yl]-6-nitro-2,3-dioxo-4H-quinoxalin-1-yl]propanoic acid	Ki	30000.0 [1]
	(S)-2-Amino-3-(6-chloro-3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionic acid	Ki	30.9 [1]
	(2S)-2-Amino-3-(6-methyl-3,5-dioxo-1,2,4-triazin-2-yl)propanoic acid	Ki	1150.0 [1]
	(S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionic acid	Ki	1980.0 [1]
	(2S)-2-Amino-3-(6-iodo-3,5-dioxo-1,2,4-triazin-2-yl)propanoic acid	Ki	19.8 [1]
	(S)-2-Amino-3-(6-bromo-3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionic acid	Ki	2.9 [1]
	2-[6-Nitro-2,3-dioxo-7-[3-[[4-(2-phenylethyl)piperazin-1-yl]methyl]pyrrol-1-yl]-4H-quinoxalin-1-yl]acetic acid	Ki	25000.0 [1]
	(2S,4R)-2-Amino-4-[(E)-3-(4-chlorophenyl)prop-2-enyl]pentanedioic acid	Ki	10000.0 [1]
	2-[7-[3-[(4-Benzylpiperazin-1-yl)methyl]pyrrol-1-yl]-6-nitro-2,3-dioxo-4H-quinoxalin-1-yl]acetic acid	Ki	20000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 33 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Glutamate receptor ionotropic kainate 5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/glutamate-receptor-ionotropic-kainate-5-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 20). Quest Database™ Glutamate receptor ionotropic kainate 5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutamate-receptor-ionotropic-kainate-5-inhibitors-ic50-ki.
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