Glutamate receptor ionotropic, AMPA 4 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Glutamic acid	Ki	868.0 [1]
	Kainic acid	Ki	1710.0 [1], 1714.0 [2]
	(S)-Ampa	Ki	40.0 [1], 155.0 [2]
	2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline	IC50	1100.0 [1]
	2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline	Ki	600.0 [1]
	Tezampanel	Ki	50000.0 [1], 50500.0 [2]
	(2S,4R)-2-Amino-4-[(E)-3-naphthalen-2-ylprop-2-enyl]pentanedioic acid	Ki	10000.0 [1]
	6-(4-Amino-3,5-dimethylphenyl)-8-[(3-bromo-4,5-dihydro-1,2-oxazol-5-yl)methyl]-3,10-dihydro-2H-[1,4]dioxino[2,3-h][2,3]benzodiazepin-9-one	Ki	7400.0 [1], 11400.0 [2]
	alpha-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID	Ki	40.0 [1]
	Willardiine	Ki	8850.0 [1]
	Argiotoxin 636	IC50	430.0 [1]
	2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-YL)-propionic acid	Ki	305.0 [1]
	Iodo-willardiine	Ki	972.0 [1]
	Bromo-willardiine	Ki	457.0 [1]
	2-Amino-3-(4-bromo-3-hydroxyisoxazol-5-YL)propanoic acid	Ki	11700.0 [1]
	Cl-HIBO	Ki	11900.0 [1]
	2-[(3-Bromophenyl)methyl]-6,8-dichloro-1,1-dioxo-3,4-dihydro-1lambda6,2,4-benzothiadiazine-3-carboxylic acid	IC50	38000.0 [1]
	3-(5-Chloro-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)-L-Alanine	Ki	451.0 [1]
	3-(5-Nitro-2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)-L-Alanine	Ki	207.0 [1]
	(RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid	Ki	732.0 [1]
	2-Amino-3-(5-(2-ethyl-2H-tetrazol-5-yl)-3-hydroxyisoxazol-4-yl)propanoic acid	Ki	44.4 [1]
	2-Amino-3-(3-hydroxy-5-(2-isopropyl-2H-tetrazol-5-yl)isoxazol-4-yl)propanoic acid	Ki	2350.0 [1]
	(S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-YL)isoxazol-4-YL]propionic acid	Ki	2.7 [1]
	4-Chloro-2-(3-(naphthalen-2-yl)ureido)benzoic acid	IC50	100000.0 [1]
	2-(3-(3-Bromophenyl)ureido)-4-chlorobenzoic acid	IC50	100000.0 [1]
	(2S)-2-Amino-4-cyclopentylidenepentanedioic acid	Ki	533.0 [1]
	CID 10330442	Ki	5600.0 [1]
	(2s)-2-Amino-3-(4-Hydroxy-1,2,5-Thiadiazol-3-Yl)propanoic Acid	Ki	182.0 [1]
	(2S)-2-Amino-4-pentan-3-ylidenepentanedioic acid	Ki	4710.0 [1]
	(2r)-2-Amino-3-(4-Hydroxy-1,2,5-Thiadiazol-3-Yl)propanoic Acid	Ki	1055.0 [1]
	(2S,4R)-2-Amino-4-[(E)-3-(2-methoxyphenyl)prop-2-enyl]pentanedioic acid	Ki	10000.0 [1]
	(2S,4Z)-2-Amino-4-(2-methylpropylidene)pentanedioic Acid	Ki	10300.0 [1]
	(S)-2-Amino-3-(6-chloro-3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionic acid	Ki	3.6 [1]
	(2S)-2-Amino-3-(6-methyl-3,5-dioxo-1,2,4-triazin-2-yl)propanoic acid	Ki	89.0 [1]
	(S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionic acid	Ki	189.0 [1]
	(2S)-2-Amino-3-(6-iodo-3,5-dioxo-1,2,4-triazin-2-yl)propanoic acid	Ki	19.9 [1]
	(3S,4Ar,6S,8aR)-6-[(4-carboxyimidazol-1-yl)methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid;dihydrochloride	Ki	262000.0 [1]
	(S)-2-Amino-3-(6-bromo-3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionic acid	Ki	7.9 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

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References

This online tool may be cited as follows

MLA	"Quest Database™ Glutamate receptor ionotropic, AMPA 4 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/glutamate-receptor-ionotropic-ampa-4-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 21). Quest Database™ Glutamate receptor ionotropic, AMPA 4 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/glutamate-receptor-ionotropic-ampa-4-inhibitors-ic50-ki.
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