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Galectin-1 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
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Standard Type
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▼
Standard Values (in nM)
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▼
beta-LactoseIC50800000.0 [1]
alpha D-GalactoseIC5050000000.0 [1]
1-((2S,3R,4R,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-tetrahydro-2H-pyran-2-yl)propan-2-oneIC505000000.0 [1]
(2R,3R,4R,5R,6S)-2-(Hydroxymethyl)-6-[(E)-prop-1-enyl]oxane-3,4,5-triolIC505000000.0 [1]
(2R,3R,4R,5R,6S)-2-(Hydroxymethyl)-6-[2-(3-nitrophenyl)prop-2-enyl]oxane-3,4,5-triolIC505000000.0 [1]
Methyl (E)-3-phenyl-4-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-2-enoateIC50313000.0 [1]
(2R,3R,4R,5R,6S)-2-(Hydroxymethyl)-6-[(E)-3-phenylprop-2-enyl]oxane-3,4,5-triolIC505000000.0 [1]
Methyl (E)-4-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-2-enoateIC505000000.0 [1]
(2R,3R,4R,5R,6S)-2-(Hydroxymethyl)-6-[(E)-3-[3-[(E)-3-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]prop-1-enyl]phenyl]prop-2-enyl]oxane-3,4,5-triolIC505000000.0 [1]
(2R,3R,4R,5R,6S)-2-(Hydroxymethyl)-6-[2-(4-methoxyphenyl)prop-2-enyl]oxane-3,4,5-triolIC505000000.0 [1]
4-Methyl-N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzenesulfonamideIC505000000.0 [1]
4-Bromo-N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzenesulfonamideIC505000000.0 [1]
N-[4-Methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]naphthalene-2-sulfonamideIC505000000.0 [1]
2-Chloro-N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzenesulfonamideIC505000000.0 [1]
4-Tert-butyl-N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzenesulfonamideIC505000000.0 [1]
2,5-Dibromo-N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzenesulfonamideIC505000000.0 [1]
(2S,3R,4R,5R,6R)-2-[[2-(Benzylamino)-4-methyl-1,3-thiazol-5-yl]methyl]-6-(hydroxymethyl)oxane-3,4,5-triolIC505000000.0 [1]
(2R,3R,4R,5R,6S)-2-(Hydroxymethyl)-6-[[4-methyl-2-[(4-nitrophenyl)methylamino]-1,3-thiazol-5-yl]methyl]oxane-3,4,5-triolIC502500000.0 [1]
N-[4-Methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzamideIC505000000.0 [1]
N-[4-Methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]-4-nitrobenzamideIC505000000.0 [1]
4-Methoxy-N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzamideIC505000000.0 [1]
4-Bromo-N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]benzamideIC502500000.0 [1]
N-[4-Methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]-2-phenylacetamideIC505000000.0 [1]
N-[4-Methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]acetamideIC505000000.0 [1]
Methyl N-[4-methyl-5-[[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]methyl]-1,3-thiazol-2-yl]carbamateIC505000000.0 [1]
(2S,3S,4R,5S,6S)-2-[4-[[(2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]sulfanylmethyl]triazol-1-yl]-6-(hydroxymethyl)oxane-3,4,5-triolIC50600000.0 [1]
(2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-6-[6-[(2R,3S,4S,5R,6S)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]sulfanylhexa-2,4-diynylsulfanyl]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triolIC50300000.0 [1]
(2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-prop-2-ynylsulfanyloxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triolIC50600000.0 [1]
(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-prop-2-ynylsulfanyloxane-3,4,5-triolIC505000000.0 [1]
[(2S,3R,4R,5R,6R)-2-[3-[4-[3-[(2R,3S,4S,5R,6S)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]sulfanylprop-1-ynyl]phenyl]prop-2-ynylsulfanyl]-3-hydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-4-yl] acetateIC50300000.0 [1]
(2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-[3-[4-[3-[(2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylprop-1-ynyl]phenyl]prop-2-ynylsulfanyl]oxane-3,4,5-triolIC502500000.0 [1]
Dimeric GalactosideIC505000000.0 [1]
(2R,3S,4R,5S,6S)-2-[(2S,3R,4S,5S,6S)-6-[4-[[(2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]sulfanylmethyl]triazol-1-yl]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triolIC50300000.0 [1]
(2R,3S,4R,5S,6S)-2-[(2S,3R,4S,5S,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-[4-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylmethyl]triazol-1-yl]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triolIC50300000.0 [1]
(2S,3S,4R,5S,6S)-2-(Hydroxymethyl)-6-[4-[[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylmethyl]triazol-1-yl]oxane-3,4,5-triolIC505000000.0 [1]
Items per page: 1 - 10 of 35
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References

This online tool may be cited as follows

MLA

"Quest Database™ Galectin-1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/galectin-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Galectin-1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/galectin-1-inhibitors-ic50-ki.
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