 | Ethyl (7S)-15-methoxy-12-oxo-2,4,11-triazatetracyclo[11.4.0.02,6.07,11]heptadeca-1(17),3,5,13,15-pentaene-5-carboxylate | Ki | 27.0 [1] |
 | L-838417 | Ki | 0.7 [1] |
 | 2-(4-Chlorophenyl)-3aH-pyrazolo[4,3-c]quinolin-3-one | IC50 | 4.0 [1] |
 | 3-[3-Tert-butyl-2-[(2-methyl-1,2,4-triazol-3-yl)methoxy]pyrazolo[1,5-d][1,2,4]triazin-7-yl]-5-methyl-1,2-oxazole | Ki | 0.8 [1] |
 | 7-Ethyl-4-[4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl]-7H-imidazo[4,5-c]pyridazine | Ki | 2.47 [1] |
 | 13-(4-Methyl-1,3-thiazol-2-yl)-15-pyridin-4-yl-4,11-diazatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,5,13-pentaen-12-one | Ki | 0.6 [1] |
 | 13-(4-Methyl-1,3-thiazol-2-yl)-15-phenyl-4,11-diazatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,5,13-pentaen-12-one | Ki | 0.3 [1] |
 | 3-(2-Chlorobenzyloxy)-2-(4-chlorophenyl)-6,7,8,9-tetrahydro-2H-pyrazolo[4,3-c]quinoline | IC50 | 271.0 [1] |
 | 4-(4-Chlorophenyl)-5-[(2-chlorophenyl)methoxy]-12-oxa-3,4,8-triazatricyclo[7.4.0.02,6]trideca-1(9),2,5,7-tetraene | IC50 | 461.0 [1] |
 | 2-(4-Chlorophenyl)-3-[(4-fluorophenyl)methoxy]-6,7,8,9-tetrahydropyrazolo[4,3-c]quinoline | IC50 | 57.0 [1] |
 | 2-(1,3-Benzodioxol-5-yl)-3-[(2-chlorophenyl)methoxy]pyrazolo[4,3-c]quinoline | IC50 | 155.0 [1] |
 | 2-(4-Chlorophenyl)-3-(cyclopropylmethoxy)-8-imidazol-1-ylpyrazolo[4,3-c]quinoline | IC50 | 2114.0 [1] |
 | 3-(2-Chlorobenzyloxy)-2-(4-chlorophenyl)-2H-pyrazolo[4,3-c]quinoline | IC50 | 265.0 [1] |
 | 2-(4-Chlorophenyl)-3-(cyclopropylmethoxy)-2H-pyrazolo[4,3-c]quinoline | IC50 | 472.0 [1] |
 | 4-(4-Chlorophenyl)-5-[(2-chlorophenyl)methoxy]-3,4,8-triazatricyclo[7.5.0.02,6]tetradeca-1(9),2,5,7-tetraene | IC50 | 605.0 [1] |
 | 2-(4-Chlorophenyl)-3-[(2-chlorophenyl)methoxy]-8,8-dimethyl-7,9-dihydro-6H-pyrazolo[4,3-c]quinoline | IC50 | 213.0 [1] |
 | 2-(4-Chlorophenyl)-3-[(4-chlorophenyl)methoxy]-6,7,8,9-tetrahydropyrazolo[4,3-c]quinoline | IC50 | 177.0 [1] |
 | 3-(2-Chlorophenoxy)-2-(4-chlorophenyl)-6,7,8,9-tetrahydropyrazolo[4,3-c]quinoline | IC50 | 3000.0 [1] |
 | 3-(2-Chlorobenzyloxy)-2-(2-fluorophenyl)-2H-pyrazolo[4,3-c]quinoline | IC50 | 2.0 [1] |
 | 2-(4-Chlorophenyl)-3-(cyclopropylmethoxy)-6,7,8,9-tetrahydropyrazolo[4,3-c]quinoline | IC50 | 185.0 [1] |
 | 2-(4-Chlorophenyl)-3-[(2-fluorophenyl)methoxy]-6,7,8,9-tetrahydropyrazolo[4,3-c]quinoline | IC50 | 154.0 [1] |
 | 5-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-4'-(ethylsulfonyl)-2'-methoxy-[1,1'-biphenyl]-2-ol | Ki | 92.2 [1] |
 | 7-Ethyl-4-[4-fluoro-3-(4-propan-2-ylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 31.1 [1] |
 | 7-Cyclopropyl-4-[3-(4-ethylsulfonylphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | Ki | 31.1 [1] |
 | 4-[3-(4-Ethylsulfonyl-2-fluorophenyl)-4-fluorophenyl]-7-propan-2-ylimidazo[4,5-c]pyridazine | Ki | 34.5 [1] |
 | 4-[2',6-Difluoro-4'-(methylsulfonyl)biphenyl-3-yl]-7-ethyl-7H-imidazo[4,5-c]pyridazine | Ki | 10.9 [1] |
 | 5'-(7-Ethyl-7H-imidazo[4,5-c]pyridazin-4-yl)-2'-fluorobiphenyl-4-sulfonamide | Ki | 5.08 [1] |
 | 4-[4'-(Ethylsulfonyl)-6-fluorobiphenyl-3-yl]-7-(1-methylcyclopropyl)-7H-imidazo[4,5-c]pyridazine | Ki | 34.8 [1] |
 | 4-[4'-(Ethylsulfonyl)-6-fluorobiphenyl-3-yl]-7-(propan-2-yl)-7H-imidazo[4,5-c]pyridazine | Ki | 23.9 [1] |
 | 2'-Fluoro-5'-(7-isopropyl-7H-imidazo[4,5-c]pyridazin-4-yl)biphenyl-4-sulfonamide | Ki | 5.82 [1] |
 | 2'-Fluoro-N-methyl-5'-[7-(propan-2-yl)-7H-imidazo[4,5-c]pyridazin-4-yl]biphenyl-4-sulfonamide | Ki | 16.4 [1] |
 | 4-(6-Chloro-4'-(ethylsulfonyl)-2'-methoxy-[1,1'-biphenyl]-3-yl)-7-ethyl-7H-imidazo[4,5-c]pyridazine | Ki | 29.7 [1] |
 | 7-Ethyl-4-[3-(4-ethylsulfonyl-2-fluorophenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | Ki | 18.2 [1] |
 | 2-[2-Fluoro-5-(7-propan-2-ylimidazo[4,5-c]pyridazin-4-yl)phenyl]-5-propan-2-ylsulfonylbenzonitrile | Ki | 38.8 [1] |
 | 7-Cyclopropyl-4-[4-fluoro-3-(2-methoxy-4-methylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 37.1 [1] |
 | 7-Cyclopropyl-4-[4-fluoro-3-(2-methoxy-4-propan-2-ylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 40.5 [1] |
 | 7-Cyclobutyl-4-[4-fluoro-3-(2-methoxy-4-methylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 101.0 [1] |
 | 7-Cyclobutyl-4-[3-(4-ethylsulfonyl-2-fluorophenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | Ki | 147.0 [1] |
 | 7-Cyclopentyl-4-[3-(4-ethylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | Ki | 118.0 [1] |
 | 5-Ethylsulfonyl-2-[2-fluoro-5-(7-propan-2-ylimidazo[4,5-c]pyridazin-4-yl)phenyl]benzonitrile | Ki | 29.1 [1] |
 | 7-Cyclopropyl-4-[3-(4-ethylsulfonyl-2-fluorophenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | Ki | 67.8 [1] |
 | 5-[3-(7-Ethylimidazo[4,5-c]pyridazin-4-yl)phenyl]-2,3-dihydro-1-benzothiophene 1,1-dioxide | Ki | 102.0 [1] |
 | 7-Ethyl-4-[3-(4-methylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 56.0 [1] |
 | 4-[3-[2-(Difluoromethyl)-4-ethylsulfonylphenyl]-4-fluorophenyl]-7-ethylimidazo[4,5-c]pyridazine | Ki | 35.4 [1] |
 | 7-Cyclopropyl-4-[4-fluoro-3-(4-methylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 43.3 [1] |
 | 7-Ethyl-4-[4-fluoro-3-(4-methylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 17.7 [1] |
 | 2-[5-(7-Cyclopropylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-5-ethylsulfonylbenzonitrile | Ki | 170.0 [1] |
 | 4-[3-(4-Cyclobutylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]-7-ethylimidazo[4,5-c]pyridazine | Ki | 9.51 [1] |
 | 7-Ethyl-4-[4-fluoro-3-(2-methoxy-4-propan-2-ylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 11.7 [1] |
 | 7-Ethyl-4-[4-fluoro-3-(2-methoxy-4-methylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 7.48 [1] |
 | 4-[4-Fluoro-3-(2-fluoro-4-propan-2-ylsulfonylphenyl)phenyl]-7-propan-2-ylimidazo[4,5-c]pyridazine | Ki | 87.4 [1] |
 | 2-[5-(7-Ethylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-5-ethylsulfonylbenzonitrile | Ki | 39.2 [1] |
 | 4-[3-(4-Ethylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]-7-propan-2-ylimidazo[4,5-c]pyridazine | Ki | 14.0 [1] |
 | 4-[4-Fluoro-3-(2-methoxy-4-methylsulfonylphenyl)phenyl]-7-propan-2-ylimidazo[4,5-c]pyridazine | Ki | 8.56 [1] |
 | 7-Cyclobutyl-4-[3-(4-ethylsulfonylphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | Ki | 74.3 [1] |
 | 2-[5-(7-Ethylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-5-propan-2-ylsulfonylbenzonitrile | Ki | 108.0 [1] |
 | 4-[3-(2-Chloro-4-ethylsulfonylphenyl)-4-fluorophenyl]-7-propan-2-ylimidazo[4,5-c]pyridazine | Ki | 14.4 [1] |
 | 7-Ethyl-4-[4-fluoro-3-(2-fluoro-4-propan-2-ylsulfonylphenyl)phenyl]imidazo[4,5-c]pyridazine | Ki | 61.3 [1] |
 | 4-[3-(4-Cyclopropylsulfonyl-2-methoxyphenyl)-4-fluorophenyl]-7-ethylimidazo[4,5-c]pyridazine | Ki | 9.71 [1] |
 | 4-[5-(7-Ethylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-N-methylbenzenesulfonamide | Ki | 7.45 [1] |
 | 2-[5-(7-Cyclopropylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-5-propan-2-ylsulfonylbenzonitrile | Ki | 296.0 [1] |
 | 4-[3-(4-Ethylsulfonylphenyl)-4-fluorophenyl]-7-propylimidazo[4,5-c]pyridazine | Ki | 120.0 [1] |
 | 4-[5-(7-Cyclopentylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-3-methoxybenzenesulfonamide | Ki | 91.4 [1] |
 | [4-(7-Ethylimidazo[4,5-c]pyridazin-4-yl)-2-(4-ethylsulfonyl-2-fluorophenyl)phenyl]methanol | Ki | 678.0 [1] |
 | [4-(7-Ethylimidazo[4,5-c]pyridazin-4-yl)-2-(4-ethylsulfonyl-2-methoxyphenyl)phenyl]methanol | Ki | 1750.0 [1] |
 | 7-Ethyl-4-[3-(4-ethylsulfonylphenyl)-4-fluorophenyl]imidazo[4,5-c]pyridazine | Ki | 21.7 [1] |
 | 5-[5-(7-Ethylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-2-methyl-2,3-dihydro-1-benzothiophene 1,1-dioxide | Ki | 69.5 [1] |
 | 7-Ethyl-4-[3-(4-ethylsulfonyl-2-methoxyphenyl)-4-isocyanophenyl]imidazo[4,5-c]pyridazine | Ki | 40.6 [1] |
 | 4-[5-(7-Cyclopropylimidazo[4,5-c]pyridazin-4-yl)-2-fluorophenyl]-N-methylbenzenesulfonamide | Ki | 19.0 [1] |
 | 4-[4-Fluoro-3-(2-methoxy-4-propan-2-ylsulfonylphenyl)phenyl]-7-propan-2-ylimidazo[4,5-c]pyridazine | Ki | 19.1 [1] |
Calculator
