![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_4ffbb578f85bc75b90b9dde56fe3f9a1.svg) | 1-[4-Chloro-2-hydroxy-3-[(3S)-3-methyloxolan-3-yl]sulfonylphenyl]-3-[(1R)-2-methylcyclopent-2-en-1-yl]urea | IC50 | 10000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_10905262ac78a18ea23e71276ef2952a.svg) | (3R,4S)-N-[3-Cyano-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-3-[[(2R)-2-methylmorpholin-4-yl]methyl]-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_8a24d005d712f6378aaec52209157c86.svg) | (3R,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-3-[[methyl(2-methylpropyl)amino]methyl]-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_26fea3c2b6a69d88e8c4935dd7452ed8.svg) | (3R,4S)-N-[3-Cyano-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-3-[[methyl(2,2,2-trifluoroethyl)amino]methyl]-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_b24e8e949b8ee104cc782891855c136d.svg) | (5S)-N-[3,5-Bis(trifluoromethyl)phenyl]-2-(2,6-dimethylphenyl)-5-fluoro-3-oxo-3a,4,5,6-tetrahydro-1H-cyclopenta[c]pyrrole-6a-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_85671802fb38fe5fe866448d8a72b51e.svg) | N-[4-Chloro-3-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_9bc992431abd6506fc7a121c103f34e7.svg) | 1-(2-Methylphenyl)-5-oxo-N-[3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_3dcb69a6104171cdef8b4b394cd63e9a.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-5-oxo-1-phenylpyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_5f779de6fa3f22d59134037d3b829d0a.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_5dc57c77890f18a8e2a2f3279779ed84.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-(1,2,3,6-tetrahydropyridin-4-yl)pyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_ab3880652a304e1e4d4a3799eb2e7ed8.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3,4-bis(prop-2-enyl)pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_6cdb90db1268e564144b064688d0a606.svg) | (3S,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-ethyl-3-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_400198327f9599667798b4643de68862.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_3d58393e0a100686c0e05a1f55f437a9.svg) | (3R,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-ethyl-3-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_f5fa3c19bf7916c6aae580318c394cd8.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-(3,6-dihydro-2H-thiopyran-4-yl)-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_1dc976b909b564663a8d7ad39ef1c510.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(1-methylpiperidin-4-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_6c07f6eb8eeb6324ec5f41997ee8a5e3.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(1,1-dioxo-3,6-dihydro-2H-thiopyran-4-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_80d1e56f448dca4e0b162aa8e47fe8fc.svg) | Tert-butyl 4-[3-[[3,5-bis(trifluoromethyl)phenyl]carbamoyl]-1-(2,6-dimethylphenyl)-5-oxopyrrolidin-3-yl]piperidine-1-carboxylate | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_d68019b50954e80a409f05aa239a5d06.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(3,5-dimethylpyrazol-1-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_ca50c2eba074c33b1841b88bfa96819f.svg) | (3S,4R)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_cc30883ef7f3ff20b3d40a934e9682ff.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-(thian-4-yl)pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_56a1ecdb3f0eb52327866bcaecc527eb.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(1-hydroxyethyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_7d92e1a5231fd6f3124ee411f09465a5.svg) | (3S)-N-[3-Chloro-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_433f64ae210b478ba22788c5f9090894.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-(1-pyrrolidin-1-ylethyl)pyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_71daf8d9fbca775dc5d8cde45e0e3043.svg) | (3R,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_f8193ac4ab249ba28f9445913c6d667b.svg) | 1-(2,6-Dimethylphenyl)-3-ethyl-5-oxo-N-[3-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_c55b8c9cf04172bae50b284e5f71fa4f.svg) | (3S,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_8d70ff6eb4e737adf2808d320a84216e.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-3-ethyl-4-methyl-5-oxo-N-[3-propan-2-yloxy-5-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_2c6f670d94fb5583a4344b11cdf5ac11.svg) | (3S,4S)-N-[3-Chloro-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_ed2eb4c36a737afa4aafd6abbd630d6b.svg) | (3R,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-4-methoxy-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_ebd0504ba9b16526a122bad8d463c5c2.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-cyclopentyl-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_e2423ae464afe01dd9de3f61ffa88e40.svg) | (3S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_55accd3b5260219cb14b2304d2948097.svg) | (3S,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxo-3-propylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_d755489d5f296e7488a81c4426a7e3dc.svg) | (3R)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_ce0b3d1a6557cf03b7a87e34998f0687.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-3-ethyl-N-[3-methoxy-5-(trifluoromethyl)phenyl]-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_4a701969bca1968f05584cb63767717c.svg) | (3S,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-3-(oxan-4-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_059acfb6d2c45257c0e72ff49e5f1b96.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-cyclobutyl-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_19bbee0835d9b36d72e08ea90a696e01.svg) | (3S,4R)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-3-(oxan-4-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_6095d3a959f58061115f7249d3d3f4f7.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-3-ethyl-4-methyl-5-oxo-N-[3-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_79d3a1c4a57dae48b3e706271e61aae5.svg) | (3S,4S)-N-[3-Cyclopropyl-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_bee96420098c2378a81a2e290dfb93c2.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(2-methylbutan-2-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_ec03f8d5321fa929b77e582fa8312671.svg) | 3-[(1-Benzylpyrrolidin-3-yl)methyl]-N-[3,5-bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_7a5ed9d73f4dacb9dc2a62d7d3c1c3ce.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-cyclohexyl-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_baf873bb2a45c49ed22830ad3716c7e6.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(3-methylbutyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_cf50b1b6e1b6d3d34e7b88b47218926b.svg) | (3S,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3,4-diethyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_4c4ec1bbfa4a7e33649f8f0f311bad9c.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-N-[3-ethoxy-5-(trifluoromethyl)phenyl]-3-ethyl-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_7c39dbc9b6a457131070030d668843e1.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-butyl-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_bb1ccf44368667157214db85a9d996f2.svg) | (3S,4S)-N-[3-Cyclopentyloxy-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_b6df59e3ddc66cf6266d1e198a6d8bd5.svg) | (3R)-1-(2,6-Dimethylphenyl)-5-oxo-3-propan-2-yl-N-[3-propan-2-yloxy-5-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_61bf3091dcd308b9a8bd9e0ddbe8881e.svg) | 1-(2-Chlorophenyl)-N-[3-cyclopropyl-5-(trifluoromethyl)phenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_a638744d518dc66c39da3453619fb0fe.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2-cyclopropylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_1eefb579d832a1fc7c8e9ff7bba2f61b.svg) | N-[3-Cyclopropyl-5-(trifluoromethyl)phenyl]-1-(2-methoxyphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_d5b7a2945b7c7dd976e4113f2a4147c1.svg) | (3S,4S)-N-[3-(Dimethylamino)-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_dcf32efdc0298540a748f1a1a3b3484e.svg) | N-[3-Cyclopropyl-5-(trifluoromethyl)phenyl]-1-(2-methylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_8b320390b2fda3e65a59c667d54f3a2a.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-3-ethyl-N-[3-fluoro-5-(trifluoromethyl)phenyl]-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_7feee2276f91785b8f998fb0507dcc93.svg) | (3R)-N-[3-Cyclopropyl-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_5215ec76aed68ceeb0cf1c19c35593a8.svg) | (3R)-N-[3-Cyano-5-(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_4ccba4ee19ab47b377795044c12952a4.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-[(dimethylamino)methyl]-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_3fd6afea2feb57641c20e790d17ac6e7.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2-ethenylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_8dec4e1751336c16610524b67059da2e.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-3-ethyl-4-methyl-5-oxo-N-[3-(trifluoromethyl)-5-[[2-(trifluoromethyl)pyrrolidin-1-yl]methyl]phenyl]pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_2a2e6f63db86c9b22316178f813f40ce.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-3-ethyl-4-methyl-5-oxo-N-[3-(pyrrolidin-1-ylmethyl)-5-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_aaaadfb40d4ac7d020180c0381d9ea18.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-[2-(morpholin-4-ylmethyl)phenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_780a81a2d6a2394c959876b3e78e5300.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(2-methylprop-2-enyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_3ff3acb25deeb56fb7749a5cbf8d0cd8.svg) | (3R,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-3-[(dimethylamino)methyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_b6cb647f896c748ee676a3e1e4cf71c1.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(oxan-4-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_d47937819d324acd8214c448204b1551.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-2-(2,6-dimethylphenyl)-1-oxo-4,6,7,7a-tetrahydro-3H-pyrano[3,4-c]pyrrole-3a-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_dc8db191f006da420837cc0534089f6f.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(1H-imidazol-2-ylmethyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_ba3abfce38d0f2881a1afa35fdab9b8c.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-(phenylmethoxymethyl)pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_c140a0627a2e161ac151cc7e5eeb77ad.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-[2-methyl-6-(morpholin-4-ylmethyl)phenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_6612127414eb7ff399c6eebe2aabc818.svg) | (3R)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-[2-(methoxymethyl)-6-methylphenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_39be26aeeabca3e6adba916f871cf9c1.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2-bromo-6-methylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_7a89f4b94a945a8362bb731e81a46891.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2-fluoro-6-methylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_7d95aec9079becee3697fdf639ee79ab.svg) | (3R)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_d3e2ae15d136814e2134b060cb643a90.svg) | (3S,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-4-methyl-3-(2-methylpropyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_39defa0fcf461eedfd92ce4d20ba3abc.svg) | (3S,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_e01734924992d5ae8a33900fafc2b3a5.svg) | (3R,4S)-N-[3,5-Bis(trifluoromethyl)phenyl]-3-[[cyclobutyl(methyl)amino]methyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_685a69778e46fdf9dfe503bbc53d930d.svg) | (3R,4S)-3-[(4,4-Difluoropiperidin-1-yl)methyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxo-N-[3-propan-2-yloxy-5-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_4747f48a63fc0ca6bec0c53a65506ee8.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-5-oxo-3-propan-2-yl-1-(2-prop-2-enylphenyl)pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_21f8f912aaa05bf17944ecbfb4a7d5a9.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-[2-(hydroxymethyl)-6-methylphenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_80a13aeb2111a04d913299b67a8e28e9.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-[2-methyl-6-(2-morpholin-4-ylethyl)phenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_67c9f914cd68b681f257caebb90871ab.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2-methyl-6-prop-2-enylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_87ae58853f605fda7ce37ffe22d9bfc4.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2-methoxy-6-methylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_fe0276740ca74d7c223a3d06438d3c62.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-methyl-1-(2-methylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_d1e4229c5cab3b4e6da3b2428a607464.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-ethyl-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_45f76c913374e4a3c313295faeb3f789.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-hydroxy-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_33345271354ec276aebfb84c30d236ec.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_557589aa5cefbf9d386653a3b518ed37.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2-methylphenyl)-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_96f514118daa1522a3e5c0c858afd30d.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3,4-dimethyl-1-(2-methylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_74098eff9690c8020e085504fef4eca3.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-[2-methyl-6-(2-pyrrolidin-1-ylethyl)phenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_3d1e24352d21d26743de498e5e3b9147.svg) | (3S,4S)-1-(2,6-Dimethylphenyl)-3-ethyl-4-methyl-N-[3-(morpholin-4-ylmethyl)-5-(trifluoromethyl)phenyl]-5-oxopyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_d8107690af790a31dfc9042bf73fd29a.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-[2-(2-hydroxyethyl)-6-methylphenyl]-5-oxo-3-propan-2-ylpyrrolidine-3-carboxamide | IC50 | 300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_709a6b84512cc437ba0fbe1f0b1ca3b7.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-2-(2,6-dimethylphenyl)-1-oxo-3,4,5,6,7,7a-hexahydroisoindole-3a-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_2e1387dbe1e59c385a3a89811a204504.svg) | (3R,4S)-3-[[Cyclobutyl(methyl)amino]methyl]-1-(2,6-dimethylphenyl)-4-methyl-5-oxo-N-[3-propan-2-yloxy-5-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_b9c8e21b7eeebaa110ed036e3e3889d0.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(methoxymethyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_fbf47637103ff0fcb1c586a656774d72.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(2-methylpropyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_502245cdfb9757d8343b9f43cd231066.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-3-(3,6-dihydro-2H-pyran-4-yl)-1-(2,6-dimethylphenyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_5f66b8bdcb3d1a7e35b24f963c9d6dac.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-5-oxo-3-propylpyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_223620c6925075c195a285389834b6e0.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(2-hydroxypropan-2-yl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_c7073e425d0fd4518f5e75a921dce79f.svg) | N-[3,5-Bis(trifluoromethyl)phenyl]-1-(2,6-dimethylphenyl)-3-(hydroxymethyl)-5-oxopyrrolidine-3-carboxamide | IC50 | 30.0 [1] |
![](https://images.aatbio.com/dataset/ic50/g-protein-coupled-receptor-chemr23_aec16ac244aa8bdb4e5e60a612cbba77.svg) | Tert-butyl 4-[3-[[3,5-bis(trifluoromethyl)phenyl]carbamoyl]-1-(2,6-dimethylphenyl)-5-oxopyrrolidin-3-yl]-3,6-dihydro-2H-pyridine-1-carboxylate | IC50 | 30.0 [1] |