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G-protein coupled receptor 55 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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DronabinolIC5014200.0 [1]
N-ArachidonoylglycineIC5010000.0 [1]
Emindole SbIC5010000.0 [1]
3-Benzyl-2H-1-benzopyran-2-oneIC5010000.0 [1]
3-[1-[Oxo-(1-phenylcyclopropyl)methyl]-4-piperidinyl]-5-phenyl-1,3,4-oxadiazol-2-oneIC5012000.0 [1]
3-[1-[[1-(4-Chlorophenyl)cyclopropyl]-oxomethyl]-4-piperidinyl]-5-phenyl-1,3,4-oxadiazol-2-oneIC50640.0 [1]
Psb-SB1202IC506350.0 [1]
5-Hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methyloctan-2-yl)chromen-2-oneIC50261.0 [1]
6-Bromo-8-[(4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylic acidIC5021700.0 [1]
2-Benzylbenzo[f]chromen-3-oneIC502810.0 [1]
2H-1-Benzopyran-2-one, 7-methoxy-3-methyl-IC5010000.0 [1]
8-Methoxy-3-methylchromen-2-oneIC5010000.0 [1]
2-Methylbenzo[f]chromen-3-oneIC5010000.0 [1]
6-Methoxy-3-methyl-2H-chromen-2-oneIC5010000.0 [1]
3-Benzyl-8-methoxychromen-2-oneIC5010000.0 [1]
3-Benzyl-7-methoxychromen-2-oneIC5010000.0 [1]
3-Benzyl-5-isopropyl-8-methylchromen-2-oneIC505330.0 [1]
6-Bromo-8-methoxy-3-methylchromen-2-oneIC5010000.0 [1]
3-Benzyl-8-bromo-5-methoxychromen-2-oneIC5010000.0 [1]
3-Benzyl-5-methoxy-7-methylchromen-2-oneIC506740.0 [1]
3-Benzyl-5-methoxychromen-2-oneIC5010000.0 [1]
6-Iodo-3-methyl-chromen-2-oneIC5010000.0 [1]
5-Isopropyl-3,8-dimethylchromen-2-oneIC503450.0 [1]
(1S,2S,5S,7R,9S,10R,13S)-1,2,9-Trimethyl-7-(2-methylprop-1-enyl)-6-oxa-22-azahexacyclo[11.10.0.02,10.05,9.015,23.016,21]tricosa-15(23),16,18,20-tetraeneIC5010000.0 [1]
3-Benzyl-6-methoxychromen-2-oneIC5010000.0 [1]
3-Benzyl-6-iodochromen-2-oneIC5010000.0 [1]
8-Bromo-6-chloro-3-methylchromen-2-oneIC5010000.0 [1]
5-Methoxy-3-[(3-methoxyphenyl)methyl]chromen-2-oneIC5010000.0 [1]
7-Bromo-5-methoxy-3-[(3-methoxyphenyl)methyl]chromen-2-oneIC503990.0 [1]
7-(Bromomethyl)-5-methoxy-3-[(3-methoxyphenyl)methyl]chromen-2-oneIC5010000.0 [1]
7-(Hydroxymethyl)-5-methoxy-3-[(3-methoxyphenyl)methyl]chromen-2-oneIC5010000.0 [1]
5-Methoxy-3-[(3-methoxyphenyl)methyl]-7-pentylchromen-2-oneIC503230.0 [1]
5-Hydroxy-3-[(3-hydroxyphenyl)methyl]-7-pentylchromen-2-oneIC5010600.0 [1]
3-Benzyl-5-methoxy-7-pentylchromen-2-oneIC5010000.0 [1]
3-Benzyl-5-hydroxy-7-pentylchromen-2-oneIC5010000.0 [1]
5-Methoxy-3-[(2-methylphenyl)methyl]-7-pentylchromen-2-oneIC505080.0 [1]
5-Hydroxy-3-[(2-methylphenyl)methyl]-7-pentylchromen-2-oneIC5010000.0 [1]
5-Methoxy-3-[(3-methylphenyl)methyl]-7-pentylchromen-2-oneIC5010000.0 [1]
5-Hydroxy-3-[(3-methylphenyl)methyl]-7-pentylchromen-2-oneIC5010000.0 [1]
5-Hydroxy-3-[(2-hydroxyphenyl)methyl]-7-pentylchromen-2-oneIC5010000.0 [1]
3-[(2-Chlorophenyl)methyl]-5-methoxy-7-pentylchromen-2-oneIC509000.0 [1]
3-[(2-Chlorophenyl)methyl]-5-hydroxy-7-pentylchromen-2-oneIC5010000.0 [1]
3-[(3-Chlorophenyl)methyl]-5-methoxy-7-pentylchromen-2-oneIC5010000.0 [1]
3-[(3-Chlorophenyl)methyl]-5-hydroxy-7-pentylchromen-2-oneIC5010000.0 [1]
3-Benzyl-5-methoxy-7-(2-methyloctan-2-yl)chromen-2-oneIC5010000.0 [1]
3-Benzyl-5-hydroxy-7-(2-methyloctan-2-yl)chromen-2-oneIC50358.0 [1]
5-Methoxy-3-[(2-methoxyphenyl)methyl]-7-(2-methyloctan-2-yl)chromen-2-oneIC5010000.0 [1]
5-Methoxy-3-[(2-methoxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-oneIC5010000.0 [1]
7-(1-Butylcyclopentyl)-5-methoxy-3-[(2-methoxyphenyl)methyl]chromen-2-oneIC5010000.0 [1]
7-(1-Butylcyclopentyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]chromen-2-oneIC50854.0 [1]
7-(1-Butylcyclohexyl)-5-methoxy-3-[(2-methoxyphenyl)methyl]chromen-2-oneIC5010000.0 [1]
7-(1-Butylcyclohexyl)-5-hydroxy-3-[(2-hydroxyphenyl)methyl]chromen-2-oneIC50961.0 [1]
5-Hydroxy-7-methyl-3-[(2-methylphenyl)methyl]chromen-2-oneIC5010000.0 [1]
5-Hydroxy-7-methyl-3-[(4-methylphenyl)methyl]chromen-2-oneIC5010000.0 [1]
6-Bromo-8-[(2-chloro-4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylic acidIC5021700.0 [1]
6-Bromo-8-[(5-methoxypyridine-2-carbonyl)amino]-4-oxochromene-2-carboxylic acidIC508920.0 [1]
6-Bromo-8-[(6-methoxypyridine-3-carbonyl)amino]-4-oxochromene-2-carboxylic acidIC506200.0 [1]
8-(Naphthalene-2-carbonylamino)-4-oxochromene-2-carboxylic acidIC5029100.0 [1]
(2R,3S,4S,5S,6R)-2-(Hydroxymethyl)-6-[[(1S,12S,15R,16S,17S,20S)-1,16,20-trimethyl-16-(4-methylpent-3-enyl)-3-azapentacyclo[10.8.0.02,10.04,9.015,20]icosa-2(10),4,6,8-tetraen-17-yl]oxy]oxane-3,4,5-triolIC5010000.0 [1]
(1S,12S,15R,16S,17S,20S)-16-[(E)-4-Methoxy-4-methylpent-2-enyl]-1,16,20-trimethyl-3-azapentacyclo[10.8.0.02,10.04,9.015,20]icosa-2(10),4,6,8-tetraen-17-olIC5010000.0 [1]
5-(4-Methoxyphenyl)-3-[1-(1-phenylcyclopropanecarbonyl)piperidin-4-yl]-1,3,4-oxadiazol-2-oneIC507000.0 [1]
3-[1-(1-Phenylcyclopropanecarbonyl)piperidin-4-yl]-5-pyridin-3-yl-1,3,4-oxadiazol-2-oneIC50420.0 [1]
3-[1-[2,2-Dimethyl-1-(4-methylphenyl)cyclopropanecarbonyl]piperidin-4-yl]-5-phenyl-1,3,4-oxadiazol-2-oneIC50770.0 [1]
3-[1-[1-(2,4-Dichlorophenyl)cyclopropanecarbonyl]piperidin-4-yl]-5-phenyl-1,3,4-oxadiazol-2-oneIC502500.0 [1]
3-[1-[1-(4-Methoxyphenyl)cyclopropanecarbonyl]piperidin-4-yl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2-oneIC501800.0 [1]
(2Z)-2-[[3-[6-(4-Propan-2-ylphenoxy)hexoxy]phenyl]methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(5Z)-5-[[3-[(4-Chlorophenyl)methoxy]phenyl]methylidene]-3-methyl-2-methylsulfanylimidazol-4-oneIC5010000.0 [1]
(2Z)-2-[[3-[6-(3-Chlorophenoxy)hexoxy]phenyl]methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(2Z)-2-[[3-[6-(4-Chlorophenoxy)hexoxy]phenyl]methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(5Z)-5-[[3-[(4-Chlorophenyl)methoxy]phenyl]methylidene]-2-imino-1-methylimidazolidin-4-oneIC5010000.0 [1]
(2Z)-2-[[3-[7-(4-Chlorophenoxy)heptoxy]phenyl]methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(4Z)-4-[[3-[(4-Chlorophenyl)methoxy]phenyl]methylidene]-2-methylsulfanyl-1H-imidazol-5-oneIC5010000.0 [1]
(2Z)-2-[[3-[3-(4-Chlorophenoxy)propoxy]phenyl]methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(2Z)-2-[[3-[6-(4-Ethylphenoxy)hexoxy]phenyl]methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
3-[(2-Methoxyphenyl)methyl]-5,8-dimethylchromen-2-oneIC507140.0 [1]
3-[(2-Methoxyphenyl)methyl]-5-methyl-8-propan-2-ylchromen-2-oneIC505700.0 [1]
3-Benzyl-5-hydroxychromen-2-oneIC5010000.0 [1]
6-Methoxy-3-[(2-methoxyphenyl)methyl]-5,7,8-trimethylchromen-2-oneIC50981.0 [1]
3-Benzyl-6-methoxy-5,7,8-trimethylchromen-2-oneIC5012800.0 [1]
3-Benzyl-6-hydroxy-5,7,8-trimethylchromen-2-oneIC509320.0 [1]
3-[(4-Fluorophenyl)methyl]-6-methoxy-5,7,8-trimethylchromen-2-oneIC5013500.0 [1]
3-[(4-Fluorophenyl)methyl]-6-hydroxy-5,7,8-trimethylchromen-2-oneIC5010300.0 [1]
6-Methoxy-5,7,8-trimethyl-3-[(2-methylphenyl)methyl]chromen-2-oneIC507690.0 [1]
6-Hydroxy-5,7,8-trimethyl-3-[(2-methylphenyl)methyl]chromen-2-oneIC505160.0 [1]
5-Methoxy-3-[(4-methoxy-3,5-dimethylphenyl)methyl]-7-pentylchromen-2-oneIC5010000.0 [1]
3-[(4-Chlorophenyl)methyl]-5-methoxy-7-pentylchromen-2-oneIC503290.0 [1]
3-[(4-Fluorophenyl)methyl]-5-methoxy-7-pentylchromen-2-oneIC5010000.0 [1]
3-[(4-Bromophenyl)methyl]-5-methoxy-7-pentylchromen-2-oneIC503760.0 [1]
(2Z)-2-[(3-Chlorophenyl)methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(2Z)-2-[(E)-3-Phenylprop-2-enylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(2Z)-2-[(4-Propan-2-ylphenyl)methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
(2Z)-2-[(2,3-Dichlorophenyl)methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC506910.0 [1]
(3Z)-3-[(E)-3-Phenylprop-2-enylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-2-oneIC5010000.0 [1]
(2Z)-2-[(3-Phenoxyphenyl)methylidene]-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3-oneIC5010000.0 [1]
Ethyl 2-[3-[(Z)-(3-oxo-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-2-ylidene)methyl]phenoxy]acetateIC5010000.0 [1]
(2Z)-2-[(4-Phenylphenyl)methylidene]-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3-oneIC5010000.0 [1]
(2Z)-2-(1-Phenylethylidene)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]thiazepin-3-oneIC5010000.0 [1]
2-[3-(2,4-Dichlorobenzyloxy)benzylidene]-2,3,5,6,7,8-hexahydroimidazo[2,1-b][1,3]thiazepine-3-oneIC5010000.0 [1]
2-(2,4-Dimethoxybenzylidene)-2,3,6,7-tetrahydro-5H-imidazo[2,1-b][1,3]thiazine-3-oneIC509770.0 [1]
(2Z)-2-[(2-Methoxyphenyl)methylidene]-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazin-3-oneIC5010000.0 [1]
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References

This online tool may be cited as follows

MLA

"Quest Database™ G-protein coupled receptor 55 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Nov. 2024, https://www.aatbio.com/data-sets/g-protein-coupled-receptor-55-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, November 21). Quest Database™ G-protein coupled receptor 55 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/g-protein-coupled-receptor-55-inhibitors-ic50-ki.
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