G-protein coupled receptor 35 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Zaprinast	IC50	1220.0 [1], 10500.0 [2]
	Zaprinast	Ki	401.0 [1]
	Methyl 5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate	IC50	200.0 [1], 574.0 [2], 10400.0 [3]
	Methyl 5-[(E)-(tert-butylcarbamothioylhydrazinylidene)methyl]-1-(2,4-difluorophenyl)pyrazole-4-carboxylate	Ki	42.2 [1]
	CID 2286812	IC50	27.0 [1], 522.0 [2]
	CID 2286812	Ki	8.76 [1]
	Kynurenic acid	IC50	39000.0 [1]
	Kynurenic acid	Ki	137000.0 [1]
	2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethylfuran-2-ylidene]propanedinitrile	IC50	60.0 [1]
	2-[3-Cyano-5-(3,4-dichlorophenyl)-4,5-dimethylfuran-2-ylidene]propanedinitrile	Ki	655.0 [1]
	6-Bromo-3-methylthieno[3,2-b]thiophene-2-carboxylic acid	IC50	110.0 [1]
	Quercetin	IC50	15400.0 [1]
	Furosemide	Ki	3270.0 [1]
	Cromolyn	Ki	2340.0 [1]
	Luteolin	IC50	18600.0 [1]
	Dicumarol	Ki	39.0 [1]
	Ellagic acid	IC50	100.0 [1]
	Baicalein	IC50	28200.0 [1]
	Myricetin	IC50	2120.0 [1]
	Morin	IC50	1600.0 [1]
	Niflumic acid	Ki	3610.0 [1]
	alpha-Cyano-4-hydroxycinnamic acid	IC50	30400.0 [1]
	Pamoic acid	Ki	11.5 [1]
	Lapachol	IC50	4660.0 [1]
	Coumarin-3-carboxylic acid	IC50	100000.0 [1]
	Firefly luciferin	Ki	9860.0 [1]
	Hematein	IC50	30400.0 [1]
	Lobaric acid	IC50	4540.0 [1]
	Thieno[3,2-b]thiophene-2-carboxylic acid	IC50	57000.0 [1]
	6-Chloro-2-oxo-2H-chromene-3-carboxylic acid	IC50	13240.0 [1]
	7-Deshydroxypyrogallin-4-carboxylic acid	IC50	110.0 [1]
	6,8-Dichloro-2-oxo-2H-chromene-3-carboxylic acid	IC50	2300.0 [1]
	2-(3-Cyano-4,5,5-trimethylfuran-2-ylidene)propanedinitrile	IC50	12100.0 [1]
	6-Bromo-2-oxo-2H-chromene-3-carboxylic acid	IC50	11300.0 [1]
	6-Bromo-8-[(4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	5.18 [1]
	N-{2-[(4-Chlorobenzyl)sulfanyl]-1,3-benzothiazol-6-yl}-2-(4-morpholinylcarbonyl)benzamide	IC50	4560.0 [1]
	3-(2H-Tetrazol-5-yl)-chromen-2-one	IC50	5080.0 [1]
	2-(3-Cyano-4-methyl-1-oxaspiro[4.5]dec-3-en-2-ylidene)propanedinitrile	IC50	16400.0 [1]
	8-Nitro-2-carboxy-4-oxo-4H-1-benzopyran	Ki	13600.0 [1]
	CID 45489602	IC50	280.0 [1]
	8-[(4-Bromobenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	233.0 [1]
	8-[(2,3-Dichlorobenzoyl)amino]-6-fluoro-4-oxochromene-2-carboxylic acid	Ki	119.0 [1]
	8-[(2,4-Dichlorobenzoyl)amino]-6-fluoro-4-oxochromene-2-carboxylic acid	Ki	4.12 [1]
	8-[(3,4-Dichlorobenzoyl)amino]-6-fluoro-4-oxochromene-2-carboxylic acid	Ki	11.5 [1]
	4-Oxo-6-fluoro-8-(p-methoxybenzoylamino)-2-chromene-2-carboxylic acid	Ki	25.4 [1]
	8-Benzamido-6-chloro-4-oxochromene-2-carboxylic acid	Ki	138.0 [1]
	6-Chloro-8-[(3-methylbenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	250.0 [1]
	6-Chloro-8-[(4-nitrobenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	183.0 [1]
	6-Chloro-8-[(4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	5.5 [1]
	8-Benzamido-6-bromo-4-oxochromene-2-carboxylic acid	Ki	81.6 [1]
	6-Bromo-8-[(3-methylbenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	128.0 [1]
	4-Oxo-6-bromo-8-(p-chlorobenzoylamino)-2-chromene-2-carboxylic acid	Ki	4.79 [1]
	6-Bromo-8-[(2,4-dichlorobenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	0.94 [1]
	6-Bromo-8-[(3,4-dichlorobenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	2.18 [1]
	6-Bromo-8-[(4-cyanobenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	148.0 [1]
	6-Bromo-8-[(4-ethoxybenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	98.4 [1]
	4-Oxo-6-bromo-8-(2-methoxybenzoylamino)-4H-1-benzopyran-2-carboxylic acid	Ki	331.0 [1]
	6-Bromo-8-[(3,4-dimethoxybenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	228.0 [1]
	8-(1,3-Benzodioxole-5-carbonylamino)-6-bromo-4-oxochromene-2-carboxylic acid	Ki	15.0 [1]
	6-Bromo-8-[(2-chloro-4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	1.12 [1]
	8-[[4-(Cyclopropylmethoxy)benzoyl]amino]-4-oxochromene-2-carboxylic acid	Ki	3710.0 [1]
	4-Oxo-8-[(4-propoxybenzoyl)amino]chromene-2-carboxylic acid	Ki	8060.0 [1]
	6-Bromo-8-[(5-methoxypyridine-2-carbonyl)amino]-4-oxochromene-2-carboxylic acid	Ki	56.8 [1]
	6-Bromo-8-[(6-methoxypyridine-3-carbonyl)amino]-4-oxochromene-2-carboxylic acid	Ki	25.7 [1]
	8-Amino-6-bromo-4-oxochromene-2-carboxylic acid	Ki	3010.0 [1]
	Ethyl 6-fluoro-8-[(4-methoxybenzoyl)amino]-4-oxochromene-2-carboxylate	Ki	198.0 [1]
	8-Acetamido-4-oxo-4H-chromene-2-carboxylic acid	Ki	18500.0 [1]
	4-Oxo-8-(propanoylamino)chromene-2-carboxylic acid	Ki	6770.0 [1]
	8-[(3-Methoxy-3-oxopropanoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	18600.0 [1]
	8-(Cyclohexanecarbonylamino)-4-oxochromene-2-carboxylic acid	Ki	3580.0 [1]
	4-Oxo-8-[(2-phenylacetyl)amino]chromene-2-carboxylic acid	Ki	2720.0 [1]
	8-(Naphthalene-2-carbonylamino)-4-oxochromene-2-carboxylic acid	Ki	714.0 [1]
	4-Oxo-8-(quinoline-2-carbonylamino)chromene-2-carboxylic acid	Ki	691.0 [1]
	8-Benzamido-4-oxochromene-2-carboxylic acid	Ki	3290.0 [1]
	8-[(3-Methylbenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	4780.0 [1]
	8-[(3-Nitrobenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	4390.0 [1]
	8-[(4-Methylbenzoyl)amino]-4-oxochromene-2-carboxylic acid	Ki	697.0 [1]
	4-Oxo-8-[[4-(trifluoromethyl)benzoyl]amino]chromene-2-carboxylic acid	Ki	10300.0 [1]
	4-Oxo-8-(p-methoxybenzoylamino)-2-chromene-2-carboxylic acid	Ki	221.0 [1]
	6,8-Dibromo-2-oxo-2h-chromene-3-carboxylic acid	IC50	1080.0 [1]
	4-Oxo-6-bromo-8-(2,6-difluoro-4-methoxybenzoylamino)-2-chromene-2-carboxylic acid	Ki	0.59 [1]
	4-Bromo-2-(1H-tetrazol-5-yl)aniline	IC50	75340.0 [1]
	4-Methoxy-N-[4-(2H-tetrazol-5-yl)phenyl]benzamide	IC50	8360.0 [1]
	2-(3-Cyano-4-methyl-5-phenyl-5-(trifluoromethyl)furan-2(5H)-ylidene)malononitrile	IC50	1940.0 [1]
	[3-Cyano-4,5-dimethyl-5-(4-butylphenyl)-2,5-dihydrofuran-2-ylidene]malononitrile	IC50	6400.0 [1]
	N-[2-[(4-Chlorophenyl)methylsulfanyl]-1,3-benzothiazol-6-yl]-2-(piperidine-1-carbonyl)benzamide	IC50	30000.0 [1]
	N-[2-[(4-Chlorophenyl)methylsulfanyl]-1,3-benzothiazol-6-yl]-2-(pyrrolidine-1-carbonyl)benzamide	IC50	30000.0 [1]
	6,8-Dibromo-3-(2H-tetrazol-5-yl)chromen-2-one	IC50	380.0 [1]
	6-Bromo-8-nitro-2-oxochromene-3-carbonitrile	IC50	650.0 [1]
	N-[2-[(4-Chlorophenyl)methylsulfinyl]-1,3-benzothiazol-6-yl]-2-(morpholine-4-carbonyl)benzamide	IC50	13000.0 [1]
	6-Bromo-7-methoxy-3-(2H-tetrazol-5-yl)chromen-2-one	IC50	14130.0 [1]
	N-[2-[(R)-(4-Chlorophenyl)methylsulfinyl]-1,3-benzothiazol-6-yl]-2-(morpholine-4-carbonyl)benzamide	IC50	30000.0 [1]
	6-Bromo-7-hydroxy-3-(2H-tetrazol-5-yl)chromen-2-one	IC50	483.0 [1]
	2-(Morpholine-4-carbonyl)-N-[2-(pyridin-4-ylmethylsulfanyl)-1,3-benzothiazol-6-yl]benzamide	IC50	30000.0 [1]
	6-Bromo-7-hydroxy-2-oxochromene-3-carbonitrile	IC50	9330.0 [1]
	6-Bromo-7-methoxy-8-nitro-3-(2H-tetrazol-5-yl)chromen-2-one	IC50	2820.0 [1]
	6-Bromo-7-hydroxy-8-nitro-2-oxochromene-3-carboxylic acid	IC50	31.0 [1]
	N-[2-[(4-Chlorophenyl)methylsulfonyl]-1,3-benzothiazol-6-yl]-2-(morpholine-4-carbonyl)benzamide	IC50	5240.0 [1]
	N-[2-[1-(4-Chlorophenyl)ethylsulfanyl]-1,3-benzothiazol-6-yl]-2-(morpholine-4-carbonyl)benzamide	IC50	17000.0 [1]
	6-Bromo-7-methoxy-8-nitro-2-oxochromene-3-carbonitrile	IC50	1690.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ G-protein coupled receptor 35 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/g-protein-coupled-receptor-35-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ G-protein coupled receptor 35 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/g-protein-coupled-receptor-35-inhibitors-ic50-ki.
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