G-protein coupled bile acid receptor 1 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Prednisolone	IC50	251.0 [1]
	Cholic acid	IC50	6000.0 [1]
	2-(4-Bromophenyl)-N-[(7-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	65.0 [1]
	3-((4-Bromophenethylamino)methyl)-2-(thiophen-3-yl)quinolin-7-ol	IC50	5100.0 [1]
	3-((4-Bromophenethylamino)methyl)-6-methoxy-2-(thiophen-3-yl)quinolin-7-ol	IC50	10000.0 [1]
	3-((4-Bromophenethylamino)methyl)-2-(thiophen-3-yl)quinoline-6,7-diol	IC50	10000.0 [1]
	(2S,4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-Ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid	IC50	140.0 [1]
	2-(4-Bromophenyl)-N-[(7-methoxy-2-pyridin-3-ylquinolin-3-yl)methyl]ethanamine	IC50	65.0 [1]
	2-(4-Bromophenyl)-N-[(7-methoxy-2-pyridin-4-ylquinolin-3-yl)methyl]ethanamine	IC50	44.0 [1]
	2-(4-Chlorophenyl)-N-[(7-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	97.0 [1]
	1-(4-Chlorophenyl)-N-[(7-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]methanamine	IC50	580.0 [1]
	2-(4-Bromophenyl)-N-[(7-chloro-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	6900.0 [1]
	N-[(7-Methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]-1-(4-methylphenyl)methanamine	IC50	880.0 [1]
	1-(4-Methoxyphenyl)-N-[(7-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]methanamine	IC50	1100.0 [1]
	2-(4-Bromophenyl)-N-[(2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	5500.0 [1]
	2-(4-Bromophenyl)-N-[(6-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	10000.0 [1]
	2-(4-Bromophenyl)-N-[(7-methoxy-2-pyridin-3-yloxyquinolin-3-yl)methyl]ethanamine	IC50	10000.0 [1]
	2-(4-Bromophenyl)-N-[[2-(furan-2-yl)-7-methoxyquinolin-3-yl]methyl]ethanamine	IC50	500.0 [1]
	N-[(7-Methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]-1-phenylmethanamine	IC50	11000.0 [1]
	2-(4-Bromophenyl)-N-[(6,7-dimethoxy-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	10000.0 [1]
	2-(4-Bromophenyl)-N-[(7-ethoxy-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	4500.0 [1]
	3-((4-Bromophenethylamino)methyl)-2-(thiophen-3-yl)quinolin-6-ol	IC50	82.0 [1]
	2-(4-Bromophenyl)-N-[[2-(furan-3-yl)-7-methoxyquinolin-3-yl]methyl]ethanamine	IC50	710.0 [1]
	3-((4-Bromophenethylamino)methyl)-7-methoxy-2-(thiophen-3-yl)quinolin-6-ol	IC50	430.0 [1]
	2-(4-Bromophenyl)-N-[(7-methyl-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	5000.0 [1]
	2-(4-Bromophenyl)-N-[[2-thiophen-3-yl-7-(trifluoromethoxy)quinolin-3-yl]methyl]ethanamine	IC50	10000.0 [1]
	2-(4-Bromophenyl)-N-[[7-methoxy-2-(1,3-oxazol-2-yl)quinolin-3-yl]methyl]ethanamine	IC50	2700.0 [1]
	2-(4-Bromophenyl)-N-[(7-methoxy-2-thiophen-2-ylquinolin-3-yl)methyl]ethanamine	IC50	580.0 [1]
	2-(4-Bromophenyl)-N-[[7-methoxy-2-(1,3-thiazol-2-yl)quinolin-3-yl]methyl]ethanamine	IC50	5000.0 [1]
	3-((4-Bromophenethylamino)methyl)-2-(thiophen-3-yl)quinoline-7-carboxylic acid	IC50	10000.0 [1]
	2-(3-Bromophenyl)-N-[(7-methoxy-2-thiophen-3-ylquinolin-3-yl)methyl]ethanamine	IC50	2800.0 [1]
	2-(4-Bromophenyl)-N-[(7-methoxy-2-phenylquinolin-3-yl)methyl]ethanamine	IC50	490.0 [1]
	(3R)-N-[2-(4-Cyanophenyl)ethyl]-1-[6-(4-methylpiperazin-1-yl)-2-(trifluoromethyl)pyrimidin-4-yl]piperidine-3-carboxamide	IC50	90.0 [1]
	4-[4-[6-[(2S)-2-[2-(4-Cyanophenyl)ethylcarbamoyl]azetidin-1-yl]-2-(trifluoromethyl)pyrimidin-4-yl]phenyl]cyclohexane-1-carboxylic acid	IC50	215.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 34 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ G-protein coupled bile acid receptor 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/g-protein-coupled-bile-acid-receptor-1-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 21). Quest Database™ G-protein coupled bile acid receptor 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/g-protein-coupled-bile-acid-receptor-1-inhibitors-ic50-ki.
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