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Fructose-1,6-bisphosphatase Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Adenosine monophosphateIC501000.0 [1]
[5-(2-Amino-5-isobutyl-1,3-thiazol-4-yl)-2-furyl]phosphonic acidIC5010.0 [1], 16.0 [2], 25.0 [3]
3-(2-Carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acidIC502000.0 [1], 2500.0 [2]
5-(6-Amino-9-isobutyl-9H-purin-8-yl)furan-2-ylphosphonic acidIC50800.0 [1], 1500.0 [2]
N-{[(2z)-5-Bromo-1,3-Thiazol-2(3h)-Ylidene]carbamoyl}-3-ChlorobenzenesulfonamideIC50110.0 [1], 330.0 [2]
{[(2-Amino-8H-indeno[1,2-d][1,3]thiazol-4-yl)oxy]methyl}phosphonic acidIC50124.0 [1]
5-(6-Amino-9-neopentyl-9H-purin-8-yl)furan-2-ylphosphonic acidIC50800.0 [1]
5-(4-Amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]imidazol-2-yl)furan-2-ylphosphonic acidIC5055.0 [1], 90.0 [2]
Urea, 1-propyl-3-(m-tolylsulfonyl)-IC50320180.0 [1], 1000000.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-3,5-dimethylbenzenesulfonamideIC50140.0 [1], 350.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-chlorothiophene-2-sulfonamideIC50190.0 [1], 440.0 [2]
N-{[(2Z)-5-Bromo-1,3-thiazol-2(3H)-ylidene]carbamoyl}-4-methylbenzenesulfonamideIC50380.0 [1], 920.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-3-(trifluoromethoxy)benzenesulfonamideIC50380.0 [1], 1000.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-2-ethylbiphenyl-4-sulfonamideIC5090.0 [1], 150.0 [2]
n-[(5-Bromo-1,3-thiazol-2-yl)carbamoyl]-3-ethylbenzenesulfonamideIC50100.0 [1], 230.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-3-isopropylbenzenesulfonamideIC50290.0 [1], 690.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-3-(difluoromethoxy)benzenesulfonamideIC50100.0 [1], 210.0 [2]
4-Bromo-N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-chlorothiophene-2-sulfonamideIC5080.0 [1], 230.0 [2]
1-(5-Bromo-1,3-thiazol-2-yl)-3-(3-methylphenyl)sulfonylureaIC50170.0 [1], 310.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-4-(6-fluoropyridin-3-yl)-3-methylbenzenesulfonamideIC5090.0 [1], 130.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamideIC5060.0 [1], 90.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-isobutyl-4-methylthiophene-2-sulfonamideIC5030.0 [1], 40.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(4-methoxy-2-methylphenyl)-4-methylthiophene-2-sulfonamideIC5040.0 [1], 70.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(6-methoxypyridin-3-yl)-4-methylthiophene-2-sulfonamideIC5070.0 [1], 150.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-4-(2-methoxythiazol-4-yl)-3-methylbenzenesulfonamideIC5090.0 [1], 320.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-methoxy-4-methylthiophene-2-sulfonamideIC5070.0 [1], 150.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(2-methoxyethoxy)-4-methylthiophene-2-sulfonamideIC50210.0 [1], 310.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(6-methoxy-4-methylpyridin-3-yl)-4-methylthiophene-2-sulfonamideIC5050.0 [1], 60.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(methoxymethyl)-4-methylthiophene-2-sulfonamideIC50120.0 [1], 220.0 [2]
N,N'-(Hexane-1,6-diyldicarbamoyl)bis(3-chlorobenzene-1-sulfonamide)IC508.0 [1], 17.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(6-fluoropyridin-3-yl)-4-methylthiophene-2-sulfonamideIC5030.0 [1], 60.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-(3-methoxypropyl)-4-methylthiophene-2-sulfonamideIC5040.0 [1], 90.0 [2]
N,N'-(Heptane-1,7-Diyldicarbamoyl)bis(3-Chlorobenzenesulfonamide)IC504.0 [1], 9.0 [2]
1-(3-Chlorophenyl)sulfonyl-3-[[4-[[(3-chlorophenyl)sulfonylcarbamoylamino]methyl]phenyl]methyl]ureaIC504.0 [1], 6.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[[4-[[(3-methylphenyl)sulfonylcarbamoylamino]methyl]phenyl]methyl]ureaIC502.0 [1], 3.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[[3-[[(3-methylphenyl)sulfonylcarbamoylamino]methyl]phenyl]methyl]ureaIC506.0 [1], 12.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[6-[(3-methylphenyl)sulfonylcarbamoylamino]hex-3-ynyl]ureaIC5012.0 [1], 95.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[(E)-6-[(3-methylphenyl)sulfonylcarbamoylamino]hex-3-enyl]ureaIC5028.0 [1], 68.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[5-[(3-methylphenyl)sulfonylcarbamoylamino]pentyl]ureaIC5022.0 [1], 72.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[8-[(3-methylphenyl)sulfonylcarbamoylamino]octyl]ureaIC508.0 [1], 35.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[7-[(3-methylphenyl)sulfonylcarbamoylamino]heptyl]ureaIC505.0 [1], 12.0 [2]
1-(3-Chlorophenyl)sulfonyl-3-[8-[(3-chlorophenyl)sulfonylcarbamoylamino]octyl]ureaIC5017.0 [1], 45.0 [2]
N,N'-(Pentane-1,5-diyldicarbamoyl)bis(3-chlorobenzene-1-sulfonamide)IC5019.0 [1], 50.0 [2]
1-(3-Chlorophenyl)sulfonyl-3-[[4-[[(3-chlorophenyl)sulfonylcarbamoylamino]methyl]cyclohexyl]methyl]ureaIC5016.0 [1], 28.0 [2]
1-(3-Chlorophenyl)sulfonyl-3-[(E)-6-[(3-chlorophenyl)sulfonylcarbamoylamino]hex-3-enyl]ureaIC5014.0 [1], 40.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[6-[(3-methylphenyl)sulfonylcarbamoylamino]hexyl]ureaIC5012.0 [1], 24.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-5-methylbenzo[b]thiophene-2-sulfonamideIC5050.0 [1], 90.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-1-methyl-1H-indole-3-sulfonamideIC50190.0 [1], 390.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[2-[(3-methylphenyl)sulfonylcarbamoylamino]ethyl]ureaIC50100000.0 [1]
1-(3-Methylphenyl)sulfonyl-3-[3-[(3-methylphenyl)sulfonylcarbamoylamino]propyl]ureaIC5038530.0 [1], 100000.0 [2]
1-(3-Chlorophenyl)sulfonyl-3-[4-[(3-chlorophenyl)sulfonylcarbamoylamino]butyl]ureaIC50264.0 [1], 2755.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[4-[(3-methylphenyl)sulfonylcarbamoylamino]butyl]ureaIC50542.0 [1], 3396.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[2-[2-[(3-methylphenyl)sulfonylcarbamoylamino]ethylsulfanyl]ethyl]ureaIC5018.0 [1], 70.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[2-[2-[(3-methylphenyl)sulfonylcarbamoylamino]ethoxy]ethyl]ureaIC50151.0 [1], 827.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[2-[2-[(3-methylphenyl)sulfonylcarbamoylamino]ethylamino]ethyl]ureaIC50100000.0 [1]
1-(3-Chlorophenyl)sulfonyl-3-[2-[2-[(3-chlorophenyl)sulfonylcarbamoylamino]ethyldisulfanyl]ethyl]ureaIC5010.0 [1], 55.0 [2]
1-(3-Methylphenyl)sulfonyl-3-[2-[2-[(3-methylphenyl)sulfonylcarbamoylamino]ethyldisulfanyl]ethyl]ureaIC5012.0 [1], 29.0 [2]
N,N'-{Oxybis[(propane-3,1-diyl)carbamoyl]}bis(3-chlorobenzene-1-sulfonamide)IC5057.0 [1], 125.0 [2]
1-(3-Chlorophenyl)sulfonyl-3-[3-[3-[(3-chlorophenyl)sulfonylcarbamoylamino]propylamino]propyl]ureaIC5013727.0 [1], 43809.0 [2]
1-(3-Chlorophenylsulfonyl)-3-propylureaIC50234231.0 [1], 690276.0 [2]
1-Butyl-3-(3-chlorophenylsulfonyl)ureaIC50134180.0 [1], 196207.0 [2]
1-Butyl-3-(m-tolylsulfonyl)ureaIC5086763.0 [1], 177856.0 [2]
1-(2-Mercaptoethyl)-3-(m-tolylsulfonyl)ureaIC5010589.0 [1], 20481.0 [2]
1-(3-Chlorophenylsulfonyl)-3-(2-(methylthio)ethyl)ureaIC50277143.0 [1], 514756.0 [2]
3-Methyl-1-[1,3,7,9-tetrahydroxy-6-(3-methylbutanoyl)dibenzofuran-2-yl]butan-1-oneIC508100.0 [1]
2-Methyl-1-[1,3,7,9-tetrahydroxy-6-(2-methylbutanoyl)dibenzofuran-2-yl]butan-1-oneIC506000.0 [1]
N-(5-Bromothiazol-2-ylcarbamoyl)-6,7-dihydro-4H-thieno[3,2-c]pyran-2-sulfonamideIC50350.0 [1], 530.0 [2]
N-(5-Bromothiazol-2-ylcarbamoyl)-2-methylbenzenesulfonamideIC503500.0 [1], 6400.0 [2]
3-Amino-N-(5-bromothiazol-2-ylcarbamoyl)benzenesulfonamideIC50720.0 [1], 2100.0 [2]
AICA ribonucleotideIC5012000.0 [1]
N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amineIC501300.0 [1]
N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amineIC501000.0 [1]
d-Usninic acidIC50371000.0 [1]
Managlinat dialanetilIC5010.0 [1]
4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazolineIC501700.0 [1]
N-(3-Chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amineIC50290.0 [1]
(+)-Usnic acidIC50371000.0 [1]
N-(3-Bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amineIC504000.0 [1]
N-(3-Ethynylphenyl)-6,7-dimethoxy-4-quinazolinamineIC50900.0 [1]
4-N-(3-Bromophenyl)-7-chloroquinazoline-4,6-diamineIC5011900.0 [1]
N-(3-Bromophenyl)-7-methoxy-6-nitroquinazolin-4-amineIC5010000.0 [1]
N-(3-Bromophenyl)-7-chloro-6-nitroquinazolin-4-amineIC5010000.0 [1]
(3-Bromo-phenyl)-(2-chloromethyl-6,7-diethoxy-quinazolin-4-yl)-amineIC5010000.0 [1]
N-(3-Bromophenyl)-6,7-diethoxy-2-(methylsulfonylmethyl)quinazolin-4-amineIC5010000.0 [1]
(3-Bromo-phenyl)-(6,7-diethoxy-2-isobutyl-quinazolin-4-yl)-amineIC5010000.0 [1]
(6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-amineIC509200.0 [1]
N-(3-Bromophenyl)-6,7-dimethoxy-2-methylquinazolin-4-amineIC504500.0 [1]
(6,7-Diethoxy-quinazolin-4-yl)-(3-iodo-phenyl)-amineIC502100.0 [1]
(3-Chloro-4-fluoro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-amineIC50530.0 [1]
(3-Chloro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-amineIC501600.0 [1]
(6,7-Diethoxy-quinazolin-4-yl)-(3-ethynyl-phenyl)-amineIC502400.0 [1]
5-(2-Amino-5-(propylthio)thiazol-4-yl)furan-2-ylphosphonic acidIC5016.0 [1]
1-[4-Bromo-6-[[5-(2-methoxyethyl)-4-methylthiophen-2-yl]sulfonylcarbamoylamino]pyridin-2-yl]-3-methylureaIC5080.0 [1]
(3-Bromo-phenyl)-(6,7-diethoxy-2-phenyl-quinazolin-4-yl)-amineIC5010000.0 [1]
(2-Benzyl-6,7-diethoxy-quinazolin-4-yl)-(3-bromo-phenyl)-amineIC5010000.0 [1]
4-N-(3-Bromophenyl)-2-N,2-N-diethyl-6,7-dimethoxyquinazoline-2,4-diamineIC5010000.0 [1]
[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-bromo-phenyl)-amineIC5010000.0 [1]
(3-Bromo-phenyl)-[7-methoxy-6-(2-methoxy-ethoxy)-quinazolin-4-yl]-amineIC505500.0 [1]
(3-Bromo-phenyl)-[6-(2-methoxy-ethoxy)-quinazolin-4-yl]-amineIC502900.0 [1]
(3-Bromo-phenyl)-(6-butoxy-quinazolin-4-yl)-amineIC5010000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Fructose-1,6-bisphosphatase Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/fructose-1-6-bisphosphatase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Fructose-1,6-bisphosphatase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/fructose-1-6-bisphosphatase-inhibitors-ic50-ki.
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