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Free fatty acid receptor 2 Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
Acetic acidIC50120000.0 [1]
Propionic acidIC50130000.0 [1]
CID 57520598IC509.0 [1]
2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamideIC50800.0 [1]
2-(4-Chlorophenyl)-3-methylbutanoic acidIC50100000.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamideIC50700.0 [1]
(S)-4-CmtbIC50500.0 [1]
4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamideIC5039810.72 [1]
(3R)-3-Benzyl-4-[cyclopropyl-[4-(2,5-dichlorophenyl)-1,3-thiazol-2-yl]amino]-4-oxobutanoic acidKi199.53 [1]
(3R)-3-[Cyclopropyl-[4-[2-(6-methoxypyridin-3-yl)phenyl]-1,3-thiazol-2-yl]carbamoyl]-5-methylhexanoic acidKi251.19 [1]
(3R)-3-[Cyclopropyl-[4-[2-(6-pyrazol-1-ylpyridin-3-yl)phenyl]-1,3-thiazol-2-yl]carbamoyl]-5-methylhexanoic acidKi158.49 [1]
(3R)-3-(Cyclopentylmethyl)-4-[cyclopropyl-[4-[2-(6-pyrazol-1-ylpyridin-3-yl)phenyl]-1,3-thiazol-2-yl]amino]-4-oxobutanoic acidKi63.1 [1]
N-[(4-Chlorophenyl)methyl]-1-[2-(3,5-dimethylphenyl)acetyl]-2-methylazetidine-2-carboxamideIC5010000.0 [1]
N-[(4-Chlorophenyl)methyl]-1-[2-(3,5-dimethylphenyl)acetyl]-2-methyl-N-[2-(methylcarbamoylamino)ethyl]azetidine-2-carboxamideIC5010000.0 [1]
N-(2-Acetamidoethyl)-1-[2-(1-benzothiophen-3-yl)acetyl]-N-[(4-chlorophenyl)methyl]-2-methylazetidine-2-carboxamideIC50337.0 [1]
N-[(4-Chlorophenyl)methyl]-N,2-dimethyl-1-[2-(3-thiophen-3-ylphenyl)acetyl]azetidine-2-carboxamideIC505800.0 [1]
N-[(4-Chlorophenyl)methyl]-N,2-dimethyl-1-(naphthalene-1-carbonyl)azetidine-2-carboxamideIC503350.0 [1]
1-(5-Chloro-4-methoxythiophene-3-carbonyl)-N-[(4-chlorophenyl)methyl]-N,2-dimethylazetidine-2-carboxamideIC503350.0 [1]
N-[(4-Chlorophenyl)methyl]-1-(2-imidazo[1,2-a]pyridin-3-ylacetyl)-N,2-dimethylazetidine-2-carboxamideIC5010000.0 [1]
1-(1-Benzofuran-3-carbonyl)-N-[(4-chlorophenyl)methyl]-N,2-dimethylazetidine-2-carboxamideIC5010000.0 [1]
1-[2-(1-Benzothiophen-7-yl)acetyl]-N-[(4-chlorophenyl)methyl]-N,2-dimethylazetidine-2-carboxamideIC5010000.0 [1]
1-(1-Benzothiophene-2-carbonyl)-N-[(4-chlorophenyl)methyl]-N,2-dimethylazetidine-2-carboxamideIC5010000.0 [1]
1-(5-Chloro-1-benzothiophene-3-carbonyl)-N-[(4-chlorophenyl)methyl]-N,2-dimethylazetidine-2-carboxamideIC503350.0 [1]
1-[3-(1-Benzothiophen-3-yl)propanoyl]-N-[(4-chlorophenyl)methyl]-N,2-dimethylazetidine-2-carboxamideIC5020000.0 [1]
2-[[1-[2-(Benzimidazol-1-yl)acetyl]-2-methylazetidine-2-carbonyl]-[(4-chlorophenyl)methyl]amino]acetic acidIC5010000.0 [1]
4-[[1-(1-Benzothiophene-3-carbonyl)-2-methylazetidine-2-carbonyl]-methylamino]butanoic acidIC5010000.0 [1]
4-[[1-(1-Benzothiophene-3-carbonyl)-2-methylazetidine-2-carbonyl]-butylamino]butanoic acidIC5010000.0 [1]
4-[[1-(1-Benzothiophene-3-carbonyl)-2-methylazetidine-2-carbonyl]-cyclohexylamino]butanoic acidIC5010000.0 [1]
4-[[1-[2-(1-Benzofuran-3-yl)acetyl]-2-methylazetidine-2-carbonyl]-[(3-chlorophenyl)methyl]amino]butanoic acidIC5010000.0 [1]
2-(4-Chlorophenyl)-3-methylbutanamideIC50100000.0 [1]
(2S)-2-(4-Chlorophenyl)-3-methyl-N-(4-oxo-1,3-thiazolidin-2-ylidene)butanamideIC5020000.0 [1]
(2R,4R)-2-(2-Chlorophenyl)-3-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzoyl]-1,3-thiazolidine-4-carboxylic acidKi204.17 [1]
(3S)-3-Benzyl-4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-methylamino]-4-oxobutanoic acidKi10000.0 [1]
(3R)-4-[[4-[5-Chloro-2-(6-methoxypyridin-3-yl)phenyl]-1,3-thiazol-2-yl]-cyclopropylamino]-3-(furan-2-ylmethyl)-4-oxobutanoic acidKi100.0 [1]
(2R,4R)-2-(2-Chlorophenyl)-3-[4-(2-methoxyphenyl)benzoyl]-1,3-thiazolidine-4-carboxylic acidKi338.84 [1]
(2R,4R)-2-(2-Chlorophenyl)-3-(4-phenylbenzoyl)-1,3-thiazolidine-4-carboxylic acidKi977.24 [1]
(2S,5R)-5-(2-Chlorophenyl)-1-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzoyl]pyrrolidine-2-carboxylic acidKi398.11 [1]
(2R,4R)-3-[4-(2-Methoxyphenyl)benzoyl]-2-phenyl-1,3-thiazolidine-4-carboxylic acidKi1202.26 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(5-methylthiazol-2-yl)butanamideIC50800.0 [1]
(S)-2-(4-Chlorophenyl)-N-(4,5-dihydrothiazol-2-yl)-3-methylbutanamideIC502100.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(pyridin-4-yl)butanamideIC5056000.0 [1]
(2S)-2-(4-Chlorophenyl)-3-methyl-N-(1,3,4-thiadiazol-2-yl)butanamideIC5012000.0 [1]
(2S)-2-(4-Chlorophenyl)-3-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]butanamideIC501900.0 [1]
(S)-Methyl 2-(2-(4-chlorophenyl)-3-methylbutanamido)thiazole-5-carboxylateIC502000.0 [1]
(S)-2-(4-Chlorophenyl)-N,3-dimethyl-N-(thiazol-2-yl)butanamideIC5084000.0 [1]
(S)-N-(1-(4-Chlorophenyl)-2-methylpropyl)thiazole-2-carboxamideIC50100000.0 [1]
(S)-N-(2-(4-Chlorophenyl)-3-methylbutyl)thiazol-2-amineIC50100000.0 [1]
Rac-1-(4-chlorophenyl)-2-methyl-N-(thiazol-2-yl)propane-1-sulfonamideIC50100000.0 [1]
(S)-N-(1-(4-Chlorophenyl)-2-methylpropyl)thiazole-2-sulfonamideIC50100000.0 [1]
(S)-2-(4-Chlorophenyl)-N,3-dimethylbutanamideIC5011000.0 [1]
(S)-N-Tert-butyl-2-(4-chlorophenyl)-3-methylbutanamideIC50100000.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-phenylbutanamideIC50100000.0 [1]
Rac-2-(4-chlorophenyl)-3-methyl-N-(pyridin-3-yl)butanamideIC5049000.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(pyridin-2-yl)butanamideIC501400.0 [1]
(S)-2-(4-Chlorophenyl)-N-(6-fluoropyridin-2-yl)-3-methylbutanamideIC501100.0 [1]
(S)-2-(4-Chlorophenyl)-N-(5-fluoropyridin-2-yl)-3-methylbutanamideIC501300.0 [1]
Rac-2-(4-chlorophenyl)-3-methyl-N-(pyrimidin-2-yl)butanamideIC5053000.0 [1]
Rac-2-(4-chlorophenyl)-3-methyl-N-(pyrazin-2-yl)butanamideIC505700.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(pyridazin-3-yl)butanamideIC502300.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(oxazol-2-yl)butanamideIC5025000.0 [1]
(2S)-2-(4-Chlorophenyl)-3-methyl-N-(1,2,4-thiadiazol-5-yl)butanamideIC502000.0 [1]
(S)-2-(4-Chlorophenyl)-N-(1H-imidazol-2-yl)-3-methylbutanamideIC5020000.0 [1]
Rac-2-(4-chlorophenyl)-3-methyl-N-(1H-tetrazol-5-yl)butanamideIC50100000.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(1H-pyrazol-3-yl)butanamideIC50100000.0 [1]
Rac-(S)-2-(4-chlorophenyl)-N-(isoxazol-3-yl)-3-methylbutanamideIC5036000.0 [1]
(2S)-2-(4-Chlorophenyl)-3-methyl-N-(thiadiazol-5-yl)butanamideIC5057000.0 [1]
Rac-N-(benzo[d]thiazol-2-yl)-2-(4-chlorophenyl)-3-methylbutanamideIC503000.0 [1]
(S)-N-(5-Chlorobenzo[d]oxazol-2-yl)-2-(4-chlorophenyl)-3-methylbutanamideIC504300.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(4-(trifluoromethyl)thiazol-2-yl)butanamideIC5017000.0 [1]
(S)-N-(4-Tert-butylthiazol-2-yl)-2-(4-chlorophenyl)-3-methylbutanamideIC507900.0 [1]
2-(4-Chlorophenyl)-3-methyl-N-(4-pyridin-3-yl-1,3-thiazol-2-yl)butanamideIC50100000.0 [1]
(S)-2-(4-Chlorophenyl)-N-(4,5-dimethylthiazol-2-yl)-3-methylbutanamideIC501800.0 [1]
(S)-2-(4-Chlorophenyl)-N-(5-chlorothiazol-2-yl)-3-methylbutanamideIC50700.0 [1]
(S)-2-(4-Chlorophenyl)-3-methyl-N-(5-(trifluoromethyl)thiazol-2-yl)butanamideIC501500.0 [1]
(S)-2-(4-Chlorophenyl)-N-(5-cyanothiazol-2-yl)-3-methylbutanamideIC502000.0 [1]
(S)-2-(2-(4-Chlorophenyl)-3-methylbutanamido)thiazole-5-carboxylic acidIC5079000.0 [1]
(S)-2-(2-(4-Chlorophenyl)-3-methylbutanamido)thiazole-5-carboxamideIC5071000.0 [1]
(S)-2-(4-Chlorophenyl)-N-(5-fluorothiazol-2-yl)-3,3-dimethylbutanamideIC50700.0 [1]
(S)-2-(4-Chlorophenyl)-N-(5-chlorothiazol-2-yl)-3,3-dimethylbutanamideIC501000.0 [1]
(S)-N-(5-Bromothiazol-2-yl)-2-(4-chlorophenyl)-3,3-dimethylbutanamideIC50700.0 [1]
(S)-2-(4-Chlorophenyl)-N-(5-cyanothiazol-2-yl)-3,3-dimethylbutanamideIC501500.0 [1]
(2S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-[5-(trifluoromethyl)-1,3-thiazol-2-yl]butanamideIC501500.0 [1]
(2S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-methylsulfanyl-1,3-thiazol-2-yl)butanamideIC50500.0 [1]
(2S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-methylsulfonyl-1,3-thiazol-2-yl)butanamideIC503400.0 [1]
(S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamideIC50700.0 [1]
(2S)-2-(4-Chlorophenyl)-N-[5-[(4-chlorophenyl)methyl]-1,3-thiazol-2-yl]-3,3-dimethylbutanamideIC5025000.0 [1]
(2S)-2-(4-Chlorophenyl)-N-[5-(dimethylamino)-1,3-thiazol-2-yl]-3,3-dimethylbutanamideIC501600.0 [1]
(S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-(5-morpholinothiazol-2-yl)butanamideIC501600.0 [1]
(2S)-2-(4-Chlorophenyl)-3,3-dimethyl-N-[5-(4-methylpiperazin-1-yl)-1,3-thiazol-2-yl]butanamideIC503800.0 [1]
(2S)-2-(4-Chlorophenyl)-N-[5-(1,1-dioxo-1,4-thiazinan-4-yl)-1,3-thiazol-2-yl]-3,3-dimethylbutanamideIC502400.0 [1]
(2S)-2-(4-Chlorophenyl)-N-[5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,3-thiazol-2-yl]-3,3-dimethylbutanamideIC501200.0 [1]
(S)-2-(4-Chlorophenyl)-N-(thiazol-2-yl)propanamideIC5046000.0 [1]
(S)-2-(4-Chlorophenyl)-N-(thiazol-2-yl)butanamideIC505000.0 [1]
(S)-2-(4-Chlorophenyl)-N-(thiazol-2-yl)pentanamideIC505500.0 [1]
(S)-2-(4-Chlorophenyl)-2-cyclopropyl-N-(5-fluorothiazol-2-yl)acetamideIC501200.0 [1]
(S)-2-(4-Chlorophenyl)-4-methyl-N-(thiazol-2-yl)pentanamideIC50600.0 [1]
(S)-2-(4-Chlorophenyl)-3-cyclopropyl-N-(thiazol-2-yl)propanamideIC508800.0 [1]
(S)-2-(4-Chlorophenyl)-4-methoxy-N-(thiazol-2-yl)butanamideIC50170000.0 [1]
(S)-2-(4-Chlorophenyl)-N-(thiazol-2-yl)pent-4-enamideIC501100.0 [1]
2,2-Bis(4-chlorophenyl)-N-(thiazol-2-yl)acetamideIC50100000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Free fatty acid receptor 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/free-fatty-acid-receptor-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 21). Quest Database™ Free fatty acid receptor 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/free-fatty-acid-receptor-2-inhibitors-ic50-ki.
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