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Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-[3-(pyridin-2-ylamino)propoxy]phenyl]propanoic acidIC502500.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50230.0 [1]
MK-0429IC50810.0 [1]
(2S)-3-[[2-[(3R,5S)-1-Phenylmethoxycarbonyl-5-[(pyridin-2-ylamino)methyl]pyrrolidin-3-yl]oxyacetyl]amino]-2-[(2,4,6-trimethylbenzoyl)amino]propanoic acidIC503200.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[5-[3-[6-(methylamino)pyridin-2-yl]propyl]thiophen-2-yl]propanoic acidIC50800.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl]propanoic acidIC509.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[3-fluoro-4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50330.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[3-methyl-4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50640.0 [1]
(2S)-2-[(2-Chloro-4-fluorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50440.0 [1]
(2S)-2-[(2-Chloro-6-fluorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50280.0 [1]
(2S)-2-[(2,6-Dimethylbenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50400.0 [1]
(2S)-2-[(2-Chlorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50540.0 [1]
(2S)-2-[(3-Chlorothiophene-2-carbonyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC502900.0 [1]
(2S)-2-[(3,5-Dimethyl-1,2-oxazole-4-carbonyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50200.0 [1]
(2S)-2-[(3,5-Dichloropyridine-4-carbonyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50130.0 [1]
(2S)-3-[4-[2-[6-(Methylamino)pyridin-2-yl]ethoxy]phenyl]-2-[(1-methylcyclohexanecarbonyl)amino]propanoic acidIC50830.0 [1]
(2S)-3-[4-[2-[6-(Methylamino)pyridin-2-yl]ethoxy]phenyl]-2-[(2-methylcyclohexanecarbonyl)amino]propanoic acidIC50960.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-[2-(1-methyl-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-6-yl)ethoxy]phenyl]propanoic acidIC50250.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-[[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)acetyl]amino]phenyl]propanoic acidIC50860.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[6-[2-[6-(methylamino)pyridin-2-yl]ethoxy]pyridin-3-yl]propanoic acidIC501200.0 [1]
(2S)-2-Benzamido-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC507400.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[3,5-dimethyl-4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC508800.0 [1]
(2S)-2-[(2-Cyclopropyl-4-fluorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50510.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[5-[2-[6-(methylamino)pyridin-2-yl]ethoxy]pyridin-2-yl]propanoic acidIC50510.0 [1]
(2S)-2-[(4-Fluoro-2-methylbenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50510.0 [1]
(2S)-3-[4-[2-[6-(Methylamino)pyridin-2-yl]ethoxy]phenyl]-2-[(2,4,6-trimethylbenzoyl)amino]propanoic acidIC50380.0 [1]
(2S)-2-[(2-Ethyl-4-fluorobenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC50340.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-ylmethylcarbamoyl)phenyl]propanoic acidIC508400.0 [1]
(3S)-3-(6-Methoxypyridin-3-yl)-3-[3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]imidazolidin-1-yl]propanoic acidIC50810.0 [1]
(2S)-2-[(4-Fluoro-2-methoxybenzoyl)amino]-3-[4-[2-[6-(methylamino)pyridin-2-yl]ethoxy]phenyl]propanoic acidIC508300.0 [1]
(2S)-2-[(2,6-Dichlorobenzoyl)amino]-3-[4-[2-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-yl)ethoxy]phenyl]propanoic acidIC50270.0 [1]
Items per page: 1 - 10 of 31
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References

This online tool may be cited as follows

MLA

"Quest Database™ Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Feb. 2025, https://www.aatbio.com/data-sets/fibronectin-receptor-integrin-alpha-5-beta-1-and-alpha-v-beta-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 22). Quest Database™ Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/fibronectin-receptor-integrin-alpha-5-beta-1-and-alpha-v-beta-3-inhibitors-ic50-ki.
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