Fibroblast growth factor receptor Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	PD173074	IC50	7.0 [1], 15.0 [2], 13000.0 [3]
	Unii-NA856793UT	IC50	60.0 [1]
	1,6-Naphthyridine deriv. 20	IC50	1.0 [1], 85.0 [2], 1900.0 [3]
	1,6-Naphthyridine 16	IC50	3.6 [1], 15.0 [2], 4800.0 [3]
	1,6-Naphthyridine 17	IC50	1.0 [1], 1.9 [2], 330.0 [3]
	1,6-Naphthyridine 18	IC50	2.0 [1], 12.0 [2], 1700.0 [3]
	1,6-Naphthyridine 19	IC50	3.0 [1], 4.4 [2], 350.0 [3]
	1,6-Naphthyridine 20	IC50	0.4 [1], 2.7 [2], 200.0 [3]
	1,6-Naphthyridine 22	IC50	2.6 [1], 14.0 [2], 4500.0 [3]
	1,6-Naphthyridine 23	IC50	0.5 [1], 2.7 [2], 560.0 [3]
	1,6-Naphthyridine 24	IC50	0.5 [1], 2.0 [2], 340.0 [3]
	1,6-Naphthyridine 26	IC50	2.0 [1], 200.0 [2]
	1,6-Naphthyridine 75	IC50	2.7 [1], 6.0 [2], 56.0 [3]
	1,6-Naphthyridine 76	IC50	4.7 [1], 6.0 [2], 42.0 [3]
	1,6-Naphthyridine 77	IC50	3.0 [1], 4.0 [2], 630.0 [3]
	Pyrido[2,3-d]pyrimidine 102	IC50	15.0 [1], 88.0 [2], 6800.0 [3]
	Pyrido[2,3-d]pyrimidine 103	IC50	6.0 [1], 28.0 [2], 4600.0 [3]
	Pyrido[2,3-d]pyrimidine 104	IC50	33.0 [1], 430.0 [2], 25000.0 [3]
	Pyrido[2,3-d]pyrimidine 105	IC50	20.0 [1], 37.0 [2], 6800.0 [3]
	6-(2,6-Dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	44.0 [1], 43000.0 [2]
	1-Tert-butyl-3-[6-(2,6-dichlorophenyl)-2-[4-(diethylamino)butylamino]pyrido[2,3-d]pyrimidin-7-yl]urea	IC50	48.0 [1]
	1-[2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea	IC50	130.0 [1]
	3-(3,5-Dimethoxyphenyl)-7-N-[3-(4-methylpiperazin-1-yl)propyl]-1,6-naphthyridine-2,7-diamine	IC50	150.0 [1], 6400.0 [2]
	7-N-[4-(Diethylamino)butyl]-3-(3,5-dimethoxyphenyl)-1,6-naphthyridine-2,7-diamine	IC50	130.0 [1], 12000.0 [2]
	1,6-Naphthyridine 25	IC50	3.0 [1], 170.0 [2]
	Staurosporine	IC50	420.0 [1]
	Semaxanib	IC50	5000.0 [1]
	Canertinib	IC50	50000.0 [1]
	Tandutinib	IC50	30000.0 [1]
	Linifanib	IC50	12500.0 [1]
	Pyridone 6	IC50	1480.0 [1]
	Azd-1152hqpa	Ki	10000.0 [1]
	CID 6918852	Ki	5000.0 [1]
	9-Hydroxy-4-phenyl-6H-pyrrolo[3,4-C]carbazole-1,3-dione	IC50	50000.0 [1]
	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[2-(triazol-1-yl)ethoxy]quinazolin-4-amine	IC50	1500.0 [1]
	JNK Inhibitor VIII	Ki	4700.0 [1]
	PDGF Receptor Tyrosine Kinase Inhibitor III	IC50	29700.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 38	IC50	510.0 [1]
	1-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)phenyl]-3-(3-methylphenyl)urea	IC50	4200.0 [1]
	N-(3-Bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amine	IC50	50000.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 2	IC50	1320.0 [1]
	CID 9916282	IC50	8000.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 19	IC50	50000.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 29	IC50	1970.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 30	IC50	1260.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 68	IC50	51.0 [1]
	8-(2-Bicyclo[2.2.1]heptanyl)-2-[4-[4-(3-hydroxypropyl)piperidin-1-yl]anilino]pyrido[2,3-d]pyrimidin-7-one	IC50	8620.0 [1]
	4-(6,7-Dimethoxy-4-quinazolinyl)-N-(4-nitrophenyl)-1-piperazinecarboxamide	IC50	200000.0 [1]
	N-(2-Chloro-6-methylphenyl)-2-[(cyclopropylcarbonyl)amino]-1,3-thiazole-5-carboxamide	IC50	25000.0 [1]
	2,4-Difluoro-N-methoxy-5-[[6-(5-methyl-1,3,4-oxadiazol-2-yl)-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]benzamide	IC50	6.5 [1]
	N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)acetamide	Ki	4700.0 [1]
	N-Benzyl-4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carbothioamide	IC50	200000.0 [1]
	4-Amino-5-chloro-6-ethoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamide	Ki	4700.0 [1]
	1-Oxo-3-phenyl-1h-indene-2-carboxamide	IC50	4700.0 [1]
	(2S)-2-Amino-N-hydroxy-3-(4-hydroxyphenyl)propanamide	Ki	23000.0 [1]
	1-({4-[(3,4-Dichlorophenyl)methoxy]phenyl}methyl)azetidine-3-carboxylic acid	IC50	10000.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 28	IC50	50000.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 31	IC50	348.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 62	IC50	48.0 [1]
	2-Aminopyrido[2,3-d]pyrimidin-7(8H)-one 71	IC50	61.0 [1]
	6-Arylpyrido[2,3-d]pyrimidine deriv. 55	IC50	125.0 [1]
	6-Arylpyrido[2,3-d]pyrimidine deriv. 56	IC50	40.0 [1]
	6-Arylpyrido[2,3-d]pyrimidine deriv. 69	IC50	139.0 [1]
	8-Ethyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one	IC50	3295.0 [1]
	N8 Pyrido[2,3-d]pyrimidin-7-one deriv. 45	IC50	2980.0 [1]
	Pyrido-[2,3-d]-pyrimidin-7-one 35	IC50	1740.0 [1]
	6-Acetyl-8-cyclopentyl-5-methyl-2-(4-piperazin-1-yl-phenylamino)-8H-pyrido[2,3-d]pyrimidin-7-one	IC50	1860.0 [1]
	Thienopyrimidine deriv. 28	IC50	1500.0 [1]
	N-(1,3-Benzodioxol-5-ylmethyl)-4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carbothioamide	IC50	160000.0 [1]
	5-[[6-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2,4-difluoro-N-methoxybenzamide	IC50	21.0 [1]
	2,4-Difluoro-N-methoxy-5-[[6-(5-methyl-1,3-oxazol-2-yl)-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]benzamide	IC50	4.0 [1]
	2,4-Difluoro-N-methoxy-5-[[6-[5-(methylsulfonylmethyl)-1,3,4-oxadiazol-2-yl]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]benzamide	IC50	4.6 [1]
	N-(4-Bromophenyl)-4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carboxamide	IC50	200000.0 [1]
	1-[2-Amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-ethylurea	IC50	130.0 [1]
	N-(4-Cyanophenyl)-4-(6,7-dimethoxyquinazolin-4-yl)piperazine-1-carboxamide	IC50	200000.0 [1]
	4-(6,7-Dimethoxyquinazolin-4-yl)-N-(4-propan-2-ylphenyl)piperazine-1-carboxamide	IC50	30000.0 [1]
	3-[[5-Cyano-6-(cyclopentylamino)pyrimidin-4-yl]amino]-4-methyl-N-(1,2-oxazol-3-yl)benzamide	IC50	50000.0 [1]
	5-[[6-[5-[Difluoro(methylsulfonyl)methyl]-1,3,4-oxadiazol-2-yl]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]-2,4-difluoro-N-methoxybenzamide	IC50	130.0 [1]
	N-(4-Amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxy-4-methylsulfonylphenyl)acetamide	Ki	4700.0 [1]
	N-(4-Amino-5-chloro-6-ethoxypyridin-2-yl)-2-(4-methanesulfonyl-2,5-dimethoxyphenyl)acetamide	Ki	4700.0 [1]
	N-(4-Amino-5-cyano-6-isopropoxypyridin-2-yl)-2-(4-methanesulfonyl-2,5-dimethoxyphenyl)acetamide	Ki	4700.0 [1]
	N-(4-Amino-5-cyano-6-phenylpyridin-2-yl)acetamide	Ki	4700.0 [1]
	Vegfrecine	IC50	730.0 [1]
	2-Amino-6-(3,5-dimethoxyphenyl)-8-methylpyrido[2,3-d]pyrimidine-7(8H)-one	IC50	126.0 [1]
	1-Tert-butyl-3-[6-(2,6-dichlorophenyl)-2-[4-[2-(diethylamino)ethoxy]anilino]pyrido[2,3-d]pyrimidin-7-yl]urea	IC50	51.0 [1]
	6-(2,6-Dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one	IC50	50000.0 [1]
	6-Bromo-8-cyclopentyl-2-(4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one	IC50	80.0 [1]
	7-((1H-Imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole	IC50	34355.0 [1]
	7-[(4-Methylpiperazin-1-yl)methyl]-3-thiophen-3-yl-1,4-dihydroindeno[1,2-c]pyrazole	IC50	50000.0 [1]
	6-Arylpyrido[2,3-d]pyrimidine deriv. 13	IC50	82.0 [1]
	1-[2-Amino-6-(2,6-dimethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea	IC50	400.0 [1]
	1-[2-Amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea	IC50	780.0 [1]
	6-Arylpyrido[2,3-d]pyrimidine deriv. 32	IC50	33.0 [1]
	6-Arylpyrido[2,3-d]pyrimidine deriv. 47	IC50	51.0 [1]
	1-(2-Amino-6-phenylpyrido[2,3-d]pyrimidin-7-yl)-3-tert-butylurea	IC50	3710.0 [1]
	PD089828 analog 12	IC50	50000.0 [1]
	1-[2-Amino-6-(3,5-diethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea	IC50	1650.0 [1]
	PD089828 analog 31	IC50	16000.0 [1]
	C2 Pyrido[2,3-d]pyrimidin-7-one deriv. 23	IC50	44200.0 [1]
	N8 Pyrido[2,3-d]pyrimidin-7-one deriv. 40	IC50	6600.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 100 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Fibroblast growth factor receptor Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Nov. 2024, https://www.aatbio.com/data-sets/fibroblast-growth-factor-receptor-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, November 20). Quest Database™ Fibroblast growth factor receptor Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/fibroblast-growth-factor-receptor-inhibitors-ic50-ki.
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