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Fibroblast growth factor receptor 3 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Infigratinib phosphateIC504.9 [1]
Azd4547IC505.5 [1]
4-N-(3,5-Dimethoxyphenyl)-4-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-1-N-propan-2-ylcyclohexane-1,4-diamineIC5013.49 [1]
StaurosporineIC509.25 [1], 10.3 [2], 14.71 [3], 15.6 [4], 18.0 [5]
1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]pyrrolidin-3-ol;hydrochlorideIC501.82 [1], 2.51 [2], 3.02 [3], 26.92 [4], 10000.0 [5]
1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-3-ol;hydrochlorideIC500.58 [1], 0.65 [2], 1.7 [3], 16.22 [4], 10000.0 [5]
N'-(2,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamineIC50151.36 [1], 204.17 [2], 2570.4 [3], 10000.0 [4]
3-[1-(2-Aminoethyl)pyrazol-4-yl]-N-(cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)quinoxalin-6-amineIC505.01 [1], 6.76 [2], 181.97 [3], 2089.3 [4], 5888.44 [5]
2-(2-Chloro-5-methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethanolIC503.63 [1], 6.46 [2], 12.02 [3], 891.25 [4], 10000.0 [5]
[(2R)-1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]pyrrolidin-2-yl]methanolIC501.1 [1], 1.82 [2], 2.82 [3], 93.33 [4], 10000.0 [5]
N-(3,5-Dimethoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-pyrrolidin-1-ylpropyl)quinoxalin-6-amineIC500.51 [1], 1.1 [2], 2.09 [3], 16.98 [4], 9772.37 [5]
N-[3-(3-Aminopyrrolidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amineIC501.41 [1], 1.66 [2], 8.71 [3], 74.13 [4], 7762.47 [5]
1-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-(propan-2-ylamino)propan-2-olIC500.89 [1], 1.29 [2], 2.63 [3], 165.96 [4], 10000.0 [5]
N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-[3-(3-piperidin-1-ylpyrrolidin-1-yl)propyl]quinoxalin-6-amineIC501.35 [1], 3.8 [2], 6.31 [3], 229.09 [4], 6760.83 [5]
[(2S)-1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]pyrrolidin-2-yl]methanolIC500.91 [1], 1.0 [2], 2.34 [3], 23.99 [4], 10000.0 [5]
2-[4-[7-[N-(2-Aminoethyl)-3,5-dimethoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanol;hydrochlorideIC501.51 [1], 2.69 [2], 134.9 [3], 10000.0 [4]
1-(3,3-Difluoropyrrolidin-1-yl)-3-(3,5-dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propan-2-ol;hydrochlorideIC502.4 [1], 6.17 [2], 109.65 [3], 10000.0 [4]
2-(2,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethanol;hydrochlorideIC5083.18 [1], 100.0 [2], 1621.81 [3], 10000.0 [4]
N-(3,5-Dimethoxyphenyl)-N-[2-[(3R,5R)-3,5-dimethylpiperidin-1-yl]ethyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC506.17 [1], 21.88 [2], 338.84 [3], 10000.0 [4]
2-[3-[Cyclopropylmethyl-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]amino]-5-methoxyphenoxy]ethanolIC503.02 [1], 37.15 [2], 1380.38 [3], 10000.0 [4]
N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-[2-(methylamino)ethyl]pyrazol-4-yl]quinoxalin-6-amineIC505.13 [1], 346.74 [2], 2137.96 [3], 5248.07 [4]
N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,6,6-tetramethylpiperidin-4-yl)ethane-1,2-diamineIC5026.92 [1], 120.23 [2], 1621.81 [3], 7762.47 [4]
[(2R)-1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-2-yl]methanolIC500.39 [1], 1.7 [2], 11.22 [3], 10000.0 [4]
1-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-methylbutan-2-olIC500.71 [1], 3.71 [2], 104.71 [3], 10000.0 [4]
1-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]piperidin-4-olIC500.89 [1], 1.58 [2], 30.9 [3], 10000.0 [4]
4-[(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)methyl]piperidin-4-olIC507.08 [1], 48.98 [2], 741.31 [3], 10000.0 [4]
2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-N-(2-hydroxyethyl)acetamideIC5012.88 [1], 158.49 [2], 891.25 [3], 10000.0 [4]
3-[Cyclopropylmethyl-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]amino]-5-methoxy-N-methylbenzamideIC502.88 [1], 10.96 [2], 354.81 [3], 10000.0 [4]
2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-N-(2-methoxyethyl)acetamideIC5030.9 [1], 128.82 [2], 2290.87 [3], 10000.0 [4]
N-[3-(3,3-Difluoroazetidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amineIC503.24 [1], 4.17 [2], 177.83 [3], 10000.0 [4]
2-[4-[7-[N-(3-Aminopropyl)-3,5-dimethoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanolIC500.81 [1], 1.7 [2], 141.25 [3], 10000.0 [4]
N-(3,5-Dimethoxyphenyl)-N-[2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]ethyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amineIC502.63 [1], 10.96 [2], 158.49 [3], 10000.0 [4]
3-[[3-[1-(2-Hydroxyethyl)pyrazol-4-yl]quinoxalin-6-yl]-(3-hydroxypropyl)amino]-5-methoxy-N-methylbenzamideIC501.7 [1], 229.09 [2], 1380.38 [3], 10000.0 [4]
N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-amineIC501.91 [1], 26.3 [2], 213.8 [3], 10000.0 [4]
2-(2-Chloro-3,5-dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethanolIC500.68 [1], 1.55 [2], 22.39 [3], 10000.0 [4]
3-[3-(2-Hydroxyethoxy)-5-methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino]propan-1-olIC503.02 [1], 26.3 [2], 478.63 [3], 10000.0 [4]
2-[3-Methoxy-5-[[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-(3-pyrrolidin-1-ylpropyl)amino]phenoxy]ethanolIC502.19 [1], 6.61 [2], 79.43 [3], 10000.0 [4]
1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]piperidine-3-carbonitrileIC501.51 [1], 3.8 [2], 72.44 [3], 10000.0 [4]
[(2S)-1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-2-yl]methanolIC500.62 [1], 1.82 [2], 25.7 [3], 10000.0 [4]
2-[4-[7-[3-Fluoro-N-(2-hydroxyethyl)-5-methoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanolIC503.8 [1], 19.95 [2], 851.14 [3], 10000.0 [4]
ErdafitinibIC503.8 [1], 5.0 [2], 15.85 [3]
Debio-1347IC5022.0 [1]
N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[4-(diethylamino)butylamino]-2-oxo-4H-pyrimido[4,5-d]pyrimidin-1-yl]methyl]phenyl]prop-2-enamideIC505.99 [1], 6.0 [2], 11.9 [3]
2-[3-Methoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-5-(trideuteriomethoxy)anilino]ethanolIC500.89 [1], 134.9 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N-propan-2-yl-N'-[3-[1-(trideuteriomethyl)pyrazol-4-yl]quinoxalin-6-yl]ethane-1,2-diamineIC502.88 [1], 13.8 [2], 7413.1 [3]
N'-[3-Methoxy-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamineIC502.75 [1], 14.13 [2], 7943.28 [3]
N'-[3-Fluoro-5-(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamineIC509.77 [1], 616.6 [2], 10000.0 [3]
N'-[3,5-Bis(trideuteriomethoxy)phenyl]-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamineIC507.59 [1], 204.17 [2], 10000.0 [3]
3-[N-[3-(1-Methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-olIC500.95 [1], 41.69 [2], 10000.0 [3]
N-[3,5-Bis(trideuteriomethoxy)phenyl]-3-(1-propan-2-ylpyrazol-4-yl)-N-(3-pyridin-4-ylprop-2-ynyl)quinoxalin-6-amineIC506.17 [1], 10.96 [2], 8317.64 [3]
N-[3,5-Bis(trideuteriomethoxy)phenyl]-1,1,2,2,3,3-hexadeuterio-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N'-(2,2,2-trifluoroethyl)propane-1,3-diamineIC509.12 [1], 177.83 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamine;hydrochlorideIC505.25 [1], 165.96 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N'-[3-(1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochlorideIC503.02 [1], 125.89 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-N-[3-(2,5-dimethylimidazol-1-yl)propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC507.76 [1], 524.81 [2], 10000.0 [3]
2-[4-[7-[3,5-Dimethoxy-N-[2-(methylamino)ethyl]anilino]quinoxalin-2-yl]pyrazol-1-yl]-N-methylacetamide;hydrochlorideIC504.68 [1], 125.89 [2], 10000.0 [3]
N-[(2-Aminophenyl)methyl]-N'-(3,5-dimethoxycyclohexa-2,4-dien-1-yl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamineIC5013.8 [1], 154.88 [2], 10000.0 [3]
3-[4-[3-[4-[7-[N-(Cyclopropylmethyl)-3,5-dimethoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]propyl]piperazin-1-yl]propan-1-ol;hydrochlorideIC502.88 [1], 870.96 [2], 4677.35 [3]
2-[4-[7-[3,5-Dimethoxy-N-[2-(propan-2-ylamino)ethyl]anilino]quinoxalin-2-yl]pyrazol-1-yl]-N-methylacetamide;hydrochlorideIC504.9 [1], 20.42 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(oxolan-2-ylmethyl)ethane-1,2-diamine;hydrochlorideIC505.37 [1], 63.1 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N-methyl-N'-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochlorideIC502.95 [1], 61.66 [2], 10000.0 [3]
N'-(3,4-Difluoro-5-methoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-(2,2,2-trifluoroethyl)propane-1,3-diamine;hydrochlorideIC50346.74 [1], 10000.0 [2]
(2S)-1-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-(propan-2-ylamino)propan-2-ol;hydrochlorideIC503.31 [1], 21.38 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(3-piperidin-1-ylpropyl)quinoxalin-6-amine;hydrochlorideIC501.15 [1], 23.44 [2], 10000.0 [3]
1,1,2,2,3,3-Hexadeuterio-3-[N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-3,5-bis(trideuteriomethoxy)anilino]propan-1-olIC502.04 [1], 61.66 [2], 10000.0 [3]
N-[(5-Chlorothiophen-2-yl)methyl]-N-(3,5-dimethoxyphenyl)-3-[1-(2-piperazin-1-ylethyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochlorideIC504.27 [1], 912.01 [2], 3162.28 [3]
N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-[3-[(2S)-2-methylpyrrolidin-1-yl]propyl]quinoxalin-6-amine;hydrochlorideIC501.7 [1], 8.32 [2], 10000.0 [3]
N'-[2-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)ethyl]-N'-propan-2-ylpropane-1,3-diamine;hydrochlorideIC5012.3 [1], 154.88 [2], 5248.07 [3]
N-(3,5-Dimethoxyphenyl)-N-[3-(2-methylpiperidin-1-yl)propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC502.4 [1], 12.02 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-N-[3-[(2S,5R)-2,5-dimethylpyrrolidin-1-yl]propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC503.55 [1], 8.13 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-N-[2-(2,4-dimethylimidazol-1-yl)ethyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC5053.7 [1], 1318.26 [2], 10000.0 [3]
N-(2-Chloro-3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(3-pyrrolidin-1-ylpropyl)quinoxalin-6-amine;hydrochlorideIC504.27 [1], 11.48 [2], 8128.31 [3]
N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(2-piperazin-1-ylethyl)quinoxalin-6-amine;hydrochlorideIC504.68 [1], 199.53 [2], 9772.37 [3]
N'-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-N'-(3,5-dimethoxyphenyl)-N-(2,2,2-trifluoroethyl)propane-1,3-diamine;hydrochlorideIC503.8 [1], 489.78 [2], 9549.93 [3]
2-[4-[7-[N-(Cyclopropylmethyl)-3-(2-hydroxyethoxy)-5-methoxyanilino]quinoxalin-2-yl]pyrazol-1-yl]ethanol;hydrochlorideIC503.39 [1], 489.78 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N-propan-2-yl-N'-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochlorideIC502.75 [1], 6.46 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-N-[(3-methoxypiperidin-3-yl)methyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amineIC507.94 [1], 933.25 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylpropane-1,3-diamine;hydrochlorideIC501.95 [1], 15.49 [2], 9332.54 [3]
N-(Cyclopropylmethyl)-3-(1-methylpyrazol-4-yl)-N-[3-(trifluoromethoxy)phenyl]quinoxalin-6-amine;hydrochlorideIC5010000.0 [1]
N'-(3,5-Dimethoxyphenyl)-N-propan-2-yl-N'-[3-(1,3,5-trimethylpyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine;hydrochlorideIC5031.62 [1], 93.33 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(2-pyrazol-1-ylethyl)quinoxalin-6-amine;hydrochlorideIC502.29 [1], 426.58 [2], 10000.0 [3]
N'-(3-Methoxyphenyl)-N'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine;hydrochlorideIC5015.14 [1], 269.15 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N-methyl-N'-[3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-yl]ethane-1,2-diamine;hydrochlorideIC506.31 [1], 15.49 [2], 10000.0 [3]
1-N-(3,5-Dimethoxyphenyl)-3-methyl-1-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-2-N-propan-2-ylbutane-1,2-diamine;hydrochlorideIC5043.65 [1], 707.95 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N'-[3-(5-ethyl-1-methylpyrazol-4-yl)quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine;hydrochlorideIC507.08 [1], 102.33 [2], 8317.64 [3]
N'-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-N'-(3,5-dimethoxyphenyl)-N-propan-2-ylethane-1,2-diamine;2,2,2-trifluoroacetic acidIC507.24 [1], 102.33 [2], 10000.0 [3]
2-[(2S)-1-[3-(3,5-Dimethoxy-N-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]anilino)propyl]pyrrolidin-2-yl]acetonitrile;hydrochlorideIC501.82 [1], 16.6 [2], 10000.0 [3]
N-(3-Fluoro-5-methoxyphenyl)-3-(1H-pyrazol-4-yl)-N-(3-pyrrolidin-1-ylpropyl)quinoxalin-6-amine;hydrochlorideIC501.95 [1], 234.42 [2], 6456.54 [3]
N-[3-(3,6-Dihydro-2H-pyridin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC502.51 [1], 7.76 [2], 9120.11 [3]
N-(3,5-Dimethoxyphenyl)-N-[3-[3-(methylamino)pyrrolidin-1-yl]propyl]-3-(1-methylpyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC503.09 [1], 199.53 [2], 8317.64 [3]
(2R)-1-(3,5-Dimethoxy-N-[3-(1-propan-2-ylpyrazol-4-yl)quinoxalin-6-yl]anilino)-3-methoxypropan-2-ol;hydrochlorideIC501.1 [1], 34.67 [2], 10000.0 [3]
N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-(3-morpholin-4-ylpropyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochlorideIC501.12 [1], 407.38 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(3-morpholin-4-ylpropyl)quinoxalin-6-amine;hydrochlorideIC502.24 [1], 20.89 [2], 10000.0 [3]
2-(N-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-3,5-dimethoxyanilino)ethanol;hydrochlorideIC501.32 [1], 128.82 [2], 10000.0 [3]
N-(3,5-Dimethoxyphenyl)-3-(1-methylpyrazol-4-yl)-N-(piperidin-4-ylmethyl)quinoxalin-6-amine;hydrochlorideIC505.89 [1], 74.13 [2], 10000.0 [3]
N'-(3,5-Dimethoxyphenyl)-N'-[3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-yl]-N-propan-2-ylethane-1,2-diamine;hydrochlorideIC502.29 [1], 8.71 [2], 7762.47 [3]
N-(Cyclopropylmethyl)-N-(3,5-dimethoxyphenyl)-3-[1-(2-piperidin-4-ylethyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochlorideIC500.87 [1], 870.96 [2], 5623.41 [3]
N-[3-(3,3-Difluoropyrrolidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-[1-(oxan-4-ylmethyl)pyrazol-4-yl]quinoxalin-6-amine;hydrochlorideIC506.61 [1], 144.54 [2], 10000.0 [3]
2-[(3,5-Dimethoxycyclohexa-2,4-dien-1-yl)-[3-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]quinoxalin-6-yl]amino]ethanolIC5051.29 [1], 2238.72 [2], 10000.0 [3]
N-[3-(3,3-Difluoropyrrolidin-1-yl)propyl]-N-(3,5-dimethoxyphenyl)-3-(1H-pyrazol-4-yl)quinoxalin-6-amine;hydrochlorideIC5014.45 [1], 812.83 [2], 10000.0 [3]
(2R)-1-(N-[3-[1-(3-Aminopropyl)pyrazol-4-yl]quinoxalin-6-yl]-3,5-dimethoxyanilino)-3-methoxypropan-2-ol;hydrochlorideIC501.41 [1], 102.33 [2], 10000.0 [3]



References

This online tool may be cited as follows

MLA

"Quest Database™ Fibroblast growth factor receptor 3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/fibroblast-growth-factor-receptor-3-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Fibroblast growth factor receptor 3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/fibroblast-growth-factor-receptor-3-inhibitors-ic50-ki.
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