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Fatty acid binding protein epidermal Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
Palmitic acidIC501200.0 [1]
Palmitic acidKi802.0 [1]
(2S,4S)-3-(6-Acetamidonaphthalen-1-yl)oxycarbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi970.0 [1], 7080.0 [2]
(2R,4R)-2,4-Diphenyl-3-[[4-(5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-thiazol-2-yl]carbamoyl]cyclobutane-1-carboxylic acidKi10000.0 [1]
3-(Naphthyloxycarbonyl)-2,4-diphenylcyclobutanecarboxylic acidKi810.0 [1], 900.0 [2]
Oleic acidKi248.0 [1]
2-((2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)-[1,1'-biphenyl]-3-yl)oxy)acetic acidKi350.0 [1]
Truxillic acidKi10000.0 [1]
2,4,6-Triisopropylbenzoic acidIC5050000.0 [1]
(E)-4-[(2-Methoxycarbonyl-5-thiophen-2-ylthiophen-3-yl)amino]-4-oxobut-2-enoic acidKi3400.0 [1]
3-Carbazol-9-yl-propionic acidIC5030000.0 [1]
5-(2-(4,5-Diphenyloxazol-2-yl)phenoxy)pentanoic acidKi2000.0 [1]
6-Chloro-4-Phenyl-2-(Piperidin-1-Yl)-3-(1h-Tetrazol-5-Yl)quinolineKi86.0 [1]
[[2'-(4,5-Diphenyl-2-oxazolyl)-1,1'-biphenyl-3-yl]oxy]acetic acidKi2000.0 [1]
(2R,4R)-3-Naphthalen-1-yloxycarbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi710.0 [1]
(1s,2s,3s,4s)-3-{[(Naphthalen-1-Yl)oxy]carbonyl}-2,4-Diphenylcyclobutane-1-Carboxylic AcidKi790.0 [1]
2,4,6-Triisopropylbenzenesulfonic acidIC5016000.0 [1]
2-(2,3-Bis(2-chlorobenzyloxy)phenyl)acetic acidKi3.0 [1]
1,3-Cyclobutanedicarboxylic acid, 2,4-bis(4-hydroxy-3-methoxyphenyl)-Ki10000.0 [1]
2-((2'-(1-Ethyl-4,5-diphenyl-1H-imidazol-2-yl)(1,1'-biphenyl)-3-yl)oxy)-acetic acidKi830.0 [1]
2-[3-[2-(1-Ethyl-4,5-diphenylimidazol-2-yl)phenyl]anilino]acetic acidKi2000.0 [1]
(2S,4S)-3-[(4-Methoxyphenyl)methoxycarbonyl]-2,4-diphenylcyclobutane-1-carboxylic acidKi2150.0 [1]
(2S,4S)-3-(9H-Fluoren-9-ylmethoxycarbonyl)-2,4-diphenylcyclobutane-1-carboxylic acidKi2560.0 [1]
(2S,4S)-3-[3-[1-[2-[2-(2-Ethoxyethoxy)ethoxy]ethyl]triazol-4-yl]phenoxy]carbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi10000.0 [1]
(2S,4S)-3-[2-(2-Hydroxyphenyl)phenoxy]carbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi1590.0 [1]
(2S,4S)-3-(3-Ethynylphenoxy)carbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi890.0 [1]
(2S,4S)-2,4-Diphenyl-3-(2-phenylphenoxy)carbonylcyclobutane-1-carboxylic acidKi770.0 [1]
(2S,4S)-3-(2-Iodophenoxy)carbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi1340.0 [1]
(2S,4S)-3-(5-Ethynylnaphthalen-1-yl)oxycarbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi3920.0 [1]
(2S,4S)-2,4-Diphenyl-3-(4-phenylphenoxy)carbonylcyclobutane-1-carboxylic acidKi2520.0 [1]
(2S,4S)-2,4-Diphenyl-3-(3-phenylphenoxy)carbonylcyclobutane-1-carboxylic acidKi850.0 [1]
(2S,4S)-2,4-Diphenyl-3-[(1R,2S)-2-phenylcyclohexyl]oxycarbonylcyclobutane-1-carboxylic acidKi180.0 [1]
(2S,4S)-3-Naphthalen-1-yloxycarbonyl-2,4-bis(2-nitrophenyl)cyclobutane-1-carboxylic acidKi10000.0 [1]
(2S,4S)-2,4-Bis(2-chlorophenyl)-3-(9H-fluoren-9-ylmethoxycarbonyl)cyclobutane-1-carboxylic acidKi890.0 [1]
(2S,4S)-2,4-Bis(2-methoxyphenyl)-3-quinolin-5-yloxycarbonylcyclobutane-1-carboxylic acidKi3930.0 [1]
Fabp-IN-1Ki550.0 [1]
(2S,4S)-2,4-Bis(2-chlorophenyl)-3-[(1R,2S)-2-phenylcyclohexyl]oxycarbonylcyclobutane-1-carboxylic acidKi1700.0 [1]
(2S,4S)-2,4-Bis(2-methoxyphenyl)-3-[(1R,2S)-2-phenylcyclohexyl]oxycarbonylcyclobutane-1-carboxylic acidKi680.0 [1]
Fabp5-IN-1Ki1720.0 [1]
(2S,4S)-2,4-Bis(4-hydroxy-3-methoxyphenyl)-3-naphthalen-1-yloxycarbonylcyclobutane-1-carboxylic acidKi10000.0 [1]
(2S,4S)-3-[(4-Fluorophenyl)methoxycarbonyl]-2,4-diphenylcyclobutane-1-carboxylic acidKi2420.0 [1]
(2S,4S)-3-(2,3-Dihydro-1H-inden-2-yloxycarbonyl)-2,4-diphenylcyclobutane-1-carboxylic acidKi1570.0 [1]
(2S,4S)-3-[(4-Bromophenyl)methoxycarbonyl]-2,4-diphenylcyclobutane-1-carboxylic acidKi1580.0 [1]
(2S,4S)-2,4-Diphenyl-3-[(1S,2R)-2-phenylcyclohexyl]oxycarbonylcyclobutane-1-carboxylic acidKi200.0 [1]
Bis(oxan-4-ylmethyl) 2,4-diphenylcyclobutane-1,3-dicarboxylateKi10000.0 [1]
(2S,4S)-2,4-Bis(4-hydroxyphenyl)-3-naphthalen-1-yloxycarbonylcyclobutane-1-carboxylic acidKi10000.0 [1]
Bis[(4-methoxyphenyl)methyl] 2,4-diphenylcyclobutane-1,3-dicarboxylateKi10000.0 [1]
(2S,4S)-2,4-Bis(2-nitrophenyl)-3-[(1R,2S)-2-phenylcyclohexyl]oxycarbonylcyclobutane-1-carboxylic acidKi10000.0 [1]
(2S,4S)-2,4-Diphenyl-3-(2,2,2-trifluoroethoxycarbonyl)cyclobutane-1-carboxylic acidKi10000.0 [1]
(2S,4S)-2,4-Bis(2-bromophenyl)-3-[(1R,2S)-2-phenylcyclohexyl]oxycarbonylcyclobutane-1-carboxylic acidKi2760.0 [1]
Dibenzyl 2,4-diphenylcyclobutane-1,3-dicarboxylateKi10000.0 [1]
Bis[(4-fluorophenyl)methyl] 2,4-diphenylcyclobutane-1,3-dicarboxylateKi10000.0 [1]
(2R,4R)-2,4-Diphenyl-3-[(3-phenylphenyl)carbamoyl]cyclobutane-1-carboxylic acidKi10000.0 [1]
(2S,4S)-2,4-Diphenyl-3-(2,4,5-trichlorophenoxy)carbonylcyclobutane-1-carboxylic acidKi800.0 [1]
(2S,4S)-2,4-Bis(2,6-dichlorophenyl)-3-[(1R,2S)-2-phenylcyclohexyl]oxycarbonylcyclobutane-1-carboxylic acidKi1230.0 [1]
2,4-Bis(3,4-dimethoxyphenyl)cyclobutane-1,3-dicarboxylic acidKi10000.0 [1]
Benzeneacetic acid, 2,3-bis((2-chlorophenyl)methoxy)-alpha-hydroxy-, (alphaS)-Ki33.0 [1]
2-[3-[2-(1-Methyl-4,5-diphenylimidazol-2-yl)phenyl]phenoxy]acetic acidKi830.0 [1]
2-[3-[2-[1-(2-Fluoroethyl)-4,5-diphenylimidazol-2-yl]phenyl]phenoxy]acetic acidKi2000.0 [1]
2-[3-[2-[1-(Carboxymethyl)-4,5-diphenylimidazol-2-yl]phenyl]anilino]acetic acidKi2000.0 [1]
2-[3-[2-[1-(2-Methylpropyl)-4,5-diphenylimidazol-2-yl]phenyl]anilino]acetic acidKi2000.0 [1]
2-[3-[2-(1-Methyl-4,5-diphenylimidazol-2-yl)phenyl]anilino]acetic acidKi2000.0 [1]
2-[3-[2-(3-Ethyl-4,5-diphenylfuran-2-yl)phenyl]phenoxy]acetic acidKi290.0 [1]
2-[3-[2-(4,5-Diphenyl-1H-imidazol-2-yl)phenyl]phenoxy]acetic acidKi2000.0 [1]
2-[3-[2-(4,5-Diphenyl-1H-imidazol-2-yl)phenyl]anilino]acetic acidKi2000.0 [1]
2-[3-[2-(4,5-Diphenylfuran-2-yl)phenyl]phenoxy]acetic acidKi2000.0 [1]
2-(2,3-Bis(2-chlorobenzyloxy)phenyl)-2-methoxyacetic acidKi9.0 [1]
2-[2,3-Bis[(2-chlorophenyl)methoxy]phenyl]-2-oxoacetic acidKi2.0 [1]
(2S,4S)-2,4-Diphenyl-3-phenylmethoxycarbonylcyclobutane-1-carboxylic acidKi3810.0 [1]
5-Carbazol-9-yl-pentanoic acidIC503000.0 [1]
3-(5-Bromo-indole-1-sulfonyl)-thiophene-2-carboxylic acidIC5014000.0 [1]
2-(Carbazole-9-sulfonyl)-benzoic acidIC5017000.0 [1]
3-(Carbazole-9-sulfonyl)-thiophene-2-carboxylic acidIC509100.0 [1]
1-(2,3-Bis(2-chlorobenzyloxy)phenyl)ethane-1,2-diolKi2000.0 [1]
2-[3-[2-(5-Ethyl-3,4-diphenylpyrazol-1-yl)phenyl]phenyl]-2-hydroxyacetic acidKi550.0 [1]
3-[2-(5-Ethyl-3,4-diphenylpyrazol-1-yl)phenyl]benzoic acidKi240.0 [1]
2,3-Bis[(2,4-dichloro-3-tritiophenyl)methoxy]benzoic acidKi2.0 [1]
Carbazole butanoic acidIC506700.0 [1]
(2S,4S)-3-Cyclohexyloxycarbonyl-2,4-diphenylcyclobutane-1-carboxylic acidKi2170.0 [1]
6-Chloranyl-2-Methyl-4-Phenyl-Quinoline-3-Carboxylic AcidKi23200.0 [1]
5-(6-Chloro-4-phenyl-2-piperidin-1-yl-quinolin-3-yl)-3H-[1,3,4]oxadiazole-2-thioneKi133.0 [1]
6-Chloro-4-phenyl-2-propan-2-ylquinoline-3-carboxylic acidKi1200.0 [1]
6-Chloranyl-4-Phenyl-2-Piperidin-1-Yl-Quinoline-3-Carboxylic AcidKi500.0 [1]
6,8-Dichloro-4-Phenyl-2-(Piperidin-1-Yl)quinoline-3-Carboxylic AcidKi120.0 [1]
6-Chloro-8-methyl-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acidKi100.0 [1]
5-(6-Chloro-4-phenyl-2-piperidin-1-yl-quinolin-3-yl)-3H-[1,3,4]oxadiazol-2-oneKi167.0 [1]
6-Chloro-2-dimethylamino-4-(3-isopropyl-phenyl)-quinoline-3-carboxylic acidKi4300.0 [1]
2-[3-[2-(4,5-Diphenyl-1H-pyrrol-2-yl)phenyl]phenoxy]acetic acidKi2000.0 [1]
2-[[5-Cyclopropyl-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-4-methylthiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC5030.0 [1]
2-[[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4,5-dimethylthiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC5030.0 [1]
2-[[4-Cyclopropyl-5-methyl-3-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC5030.0 [1]
3-[[4-Cyclopropyl-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-5-methylthiophen-2-yl]carbamoyl]bicyclo[2.2.2]oct-2-ene-2-carboxylic acidIC5040.0 [1]
2-[[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC50890.0 [1]
2-[[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4-methyl-5-(oxetan-3-yl)thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC5060.0 [1]
2-[[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-4-methyl-5-(oxetan-3-yl)thiophen-2-yl]carbamoyl]cyclohexene-1-carboxylic acidIC50227.0 [1]
2-[[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-5-methyl-4-(trifluoromethyl)thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC5060.0 [1]
2-[[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-5-ethoxycarbonyl-4-methylthiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC50130.0 [1]
2-[[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-5-(dimethylcarbamoyl)-4-methylthiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC502709.7 [1]
2-[[5-Cyclopropyl-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC50125.8 [1]
2-[[4-Cyclopropyl-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]carbamoyl]cyclopentene-1-carboxylic acidIC5038.8 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Fatty acid binding protein epidermal Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/fatty-acid-binding-protein-epidermal-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Fatty acid binding protein epidermal Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/fatty-acid-binding-protein-epidermal-inhibitors-ic50-ki.
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