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Eukaryotic translation initiation factor 2-alpha kinase 1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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CID 53469448IC50420.0 [1]
CID 53469059IC50460.0 [1]
Ripk1-IN-7IC5026.0 [1]
5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamideIC5010000.0 [1]
3-[(2,6-Dichlorophenyl)methylamino]-6,7-dimethoxy-1H-indeno[1,2-c]pyrazol-4-oneIC506.31 [1]
N-[5-(6,7-Dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1-methyl-3-oxo-2,5-diphenylpyrazole-4-carboxamideIC5010000.0 [1]
N-[(2-Chlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC50199.53 [1]
3-[[3-[(2,6-Dichlorophenyl)methylamino]-7-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-6-yl]oxy]propane-1,2-diolIC5031.62 [1]
6,7-Dimethoxy-N-[(2-methoxyphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC503162.28 [1]
6,7-Dimethoxy-N-[(2-methylphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC5063.1 [1]
N-Benzyl-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC50630.96 [1]
N-[(2,6-Dichlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC502511.89 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-5,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC50125.89 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-7-ethyl-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC50316.23 [1]
3-N-[(2-Chloro-6-methylphenyl)methyl]-7-N,7-N-dimethyl-1,4-dihydroindeno[1,2-c]pyrazole-3,7-diamineIC50251.19 [1]
7-Bromo-N-[(2-chloro-6-methylphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC50794.33 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-7-methylsulfanyl-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC501000.0 [1]
N-[(3-Chlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC501000.0 [1]
N-[(4-Chlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC502511.89 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC501584.89 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-8-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC5010000.0 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-7-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC5050.12 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-6-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC50501.19 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-5-methoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC50794.33 [1]
N-[(2,4-Dichlorophenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC501258.93 [1]
N-[(2,6-Dimethylphenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC507.94 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-amineIC5019.95 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-4,6-dioxa-11,12-diazatetracyclo[7.6.0.03,7.010,14]pentadeca-1,3(7),8,10(14),12-pentaen-13-amineIC50251.19 [1]
N-[(2,6-Dichlorophenyl)methyl]-6,7-dimethoxy-1H-[1]benzofuro[3,2-c]pyrazol-3-amineIC5063.1 [1]
N-[(2-Chloro-6-methylphenyl)methyl]-6,7-dimethoxy-1H-[1]benzothiolo[3,2-c]pyrazol-3-amineIC50501.19 [1]
N-[(2,6-Dichlorophenyl)methyl]-6,7-dimethoxy-4,4-dioxo-1H-[1]benzothiolo[3,2-c]pyrazol-3-amineIC5079.43 [1]
N-[(2,6-Dichlorophenyl)methyl]-7,8-dimethoxy-4,5-dihydro-1H-benzo[g]indazol-3-amineIC5010000.0 [1]
N-[(2,6-Dichlorophenyl)methyl]-12,13-dimethoxy-3,4-diazatricyclo[8.4.0.02,6]tetradeca-1(14),2(6),4,10,12-pentaen-5-amineIC5010000.0 [1]
1-[5-(4-Aminothieno[3,2-C]pyridin-3-Yl)-2,3-Dihydro-1h-Indol-1-Yl]-2-PhenylethanoneIC5017020.0 [1]
1-[5-[4-Amino-7-(1-methylpyrazol-4-yl)thieno[3,2-c]pyridin-3-yl]-2,3-dihydroindol-1-yl]-2-phenylethanoneIC501863.0 [1]
1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-[6-(trifluoromethyl)pyridin-2-yl]ethanoneIC5037.0 [1]
1-[5-(4-Amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoro-2,3-dihydroindol-1-yl]-2-(3,5-dimethylpyrazol-1-yl)ethanoneIC5061.0 [1]
5-{1-[(3-Chlorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amineIC50214.0 [1]
3-[1-(Phenylacetyl)-2,3-dihydro-1H-indol-5-yl]-7-(3-pyridinyl)thieno[3,2-c]pyridin-4-amineIC5012080.0 [1]
2-Amino-N-[4-Methoxy-3-(Trifluoromethyl)phenyl]-4-Methyl-3-[2-(Methylamino)quinazolin-6-Yl]benzamideIC5010000.0 [1]
Items per page: 1 - 10 of 40
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References

This online tool may be cited as follows

MLA

"Quest Database™ Eukaryotic translation initiation factor 2-alpha kinase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Dec. 2024, https://www.aatbio.com/data-sets/eukaryotic-translation-initiation-factor-2-alpha-kinase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 20). Quest Database™ Eukaryotic translation initiation factor 2-alpha kinase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/eukaryotic-translation-initiation-factor-2-alpha-kinase-1-inhibitors-ic50-ki.
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