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Epoxide hydrolase 1 Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
1,3-DicyclohexylureaIC50160.0 [1]
DicyclohexylcarbodiimideIC50470.0 [1]
TriclocarbanIC50120.0 [1]
1,3-DiphenylureaIC501200.0 [1]
t-TUCBIC5010000.0 [1]
1,3-Diphenyl-2,3-epoxy-1-propanoneIC50300.0 [1]
1-Cyclohexyl-3-dodecylureaIC50100.0 [1]
1-(Adamantane-1-yl)-3-(1-acetylpiperidine-4-yl)ureaIC5014.5 [1]
N-1-Adamantyl-N'-cyclohexylureaIC50100.0 [1]
1-Benzoyl-3-phenyl-2-thioureaIC501290.0 [1]
1,3-Bis(3,4-dichlorophenyl)ureaIC50260.0 [1]
N-Cyclohexyl-N'-phenylureaIC501390.0 [1]
1-Cyclohexyl-3-(2-phenylethyl)ureaIC50160.0 [1]
1-(2-Adamantyl)-3-cyclohexyl-ureaIC50100.0 [1]
1-Benzyl-3-cyclohexylureaIC501900.0 [1]
12-[(Cyclohexylcarbamoyl)amino]dodecanoic acidIC50100.0 [1]
1-Phenyl-3-(3-phenylpropyl)ureaIC50550.0 [1]
1-(3-Chlorophenyl)-3-cyclohexylureaIC50190.0 [1]
1-Benzoyl-3-(4-morpholin-4-yl-phenyl)-thioureaIC501720.0 [1]
4-Phenylchalcone oxideIC50200.0 [1]
1-(4-Chlorophenyl)-3-cyclohexylureaIC50400.0 [1]
1-Cyclohexyl-3-(4-fluorophenyl)ureaIC50430.0 [1]
N-Cyclohexyl-N'-(4-isopropylphenyl)ureaIC5070.0 [1]
Urea, 1-benzoyl-3-(4-chlorophenyl)-2-thio-IC501640.0 [1]
N-[2-(1-Cyclohexen-1-yl)ethyl]-N'-cyclohexylureaIC50100.0 [1]
N-Cyclohexyl((4-pyridylmethyl)amino)formamideIC502500.0 [1]
4-Fluorochalcone oxideIC50300.0 [1]
1-Cyclohexyl-3-[3-(morpholin-4-yl)propyl]ureaIC5017800.0 [1]
N-Hexyl-N'-phenylureaIC501430.0 [1]
n-Cyclohexyl-n'-(4-iodophenyl)ureaIC50120.0 [1]
1-(4-Aminophenyl)-3-cyclohexylureaIC502200.0 [1]
N-Cyclohexyl-N'-(2-(3,4-dimethoxyphenyl)ethyl)ureaIC501000.0 [1]
1-Cyclohexyl-3-naphthalen-1-ylureaIC50480.0 [1]
1-Cyclohexyl-3-cyclooctylureaIC5090.0 [1]
1-Adamantan-1-yl-3-(1-propionyl-piperidin-4-yl)-ureaIC503.19 [1]
3-(1-Acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)phenyl]ureaIC5011.5 [1]
1,3-Bis(1-adamantyl)ureaIC50100.0 [1]
Naphthalen-2-yl cyclohexylcarbamateIC50350.0 [1]
n-Cyclohexyl-n'-(propyl)phenyl ureaIC50290.0 [1]
n-Cyclohexyl-n'-decylureaIC50100.0 [1]
N-(Pyridin-4-ylcarbamothioyl)benzamideIC502280.0 [1]
1-Benzoyl-3-(1-adamantyl)thioureaIC501010.0 [1]
3-[(4-Chlorophenyl)methyl]-1-cyclohexylureaIC50190.0 [1]
1-Cyclohexyl-3-(1,2,3,4-tetrahydronaphthalen-1-yl)ureaIC50100.0 [1]
1-(1-Acetyl-piperidin-4-ylmethyl)-3-adamantan-1-yl-ureaIC505.0 [1]
1-Adamantan-1-yl-3-[1-(2,2,2-trifluoro-acetyl)-piperidin-4-yl]-ureaIC501.7 [1]
2-NonylsulfanylpropanamideIC506000.0 [1]
3-Acetyl-1-(4-chlorophenyl)thioureaIC502210.0 [1]
1-Cyclohexyl-3-tetradecylureaIC50240.0 [1]
1-(3-Chlorophenyl)-3-(cyclohexylmethyl)ureaIC50100.0 [1]
1-Cyclohexyl-3-(1,1,3,3-tetramethyl-butyl)-ureaIC503100.0 [1]
N-(4-{[4'-(Carbamoylamino)-6-Hydroxybiphenyl-3-Yl]oxy}-3,5-Dichlorophenyl)propanamideIC5026300.0 [1]
5'-[2,6-Dichloro-4-(Propanoylamino)phenoxy]-2'-Hydroxybiphenyl-4-CarboxamideIC5017200.0 [1]
CID 127052228IC5097800.0 [1]
1-[4-(4-Hydroxyphenoxy)cyclohexyl]-3-[4-(trifluoromethoxy)phenyl]ureaIC5010000.0 [1]
Benzyl 4-[4-[[4-(trifluoromethoxy)phenyl]carbamoylamino]cyclohexyl]oxybenzoateIC5010000.0 [1]
1-Cyclohexyl-3-(4-tert-butylphenyl)ureaIC50230.0 [1]
1-(Cyclohexylmethyl)-3-(4-propan-2-ylphenyl)ureaIC50100.0 [1]
1-Adamantan-1-yl-3-(1-benzoyl-piperidin-4-yl)-ureaIC501.3 [1]
1-Adamantan-1-yl-3-[1-(pyridine-2-carbonyl)-piperidin-4-yl]-ureaIC501.2 [1]
1-Adamantan-1-yl-3-[1-(pyridine-3-carbonyl)-piperidin-4-yl]-ureaIC502.1 [1]
1-Adamantan-1-yl-3-[1-(pyridine-4-carbonyl)-piperidin-4-yl]-ureaIC501.7 [1]
1-Adamantan-1-yl-3-(1-propyl-piperidin-4-yl)-ureaIC50809.0 [1]
1-Adamantan-1-yl-3-(1-butyl-piperidin-4-yl)-ureaIC501249.0 [1]
1-Adamantan-1-yl-3-(1-ethyl-piperidin-4-ylmethyl)-ureaIC503949.0 [1]
1-Adamantan-1-yl-3-(1-propyl-piperidin-4-ylmethyl)-ureaIC502578.0 [1]
1-Adamantan-1-yl-3-(1-butyl-piperidin-4-ylmethyl)-ureaIC50613.0 [1]
1-Adamantan-1-yl-3-(1-benzyl-piperidin-4-ylmethyl)-ureaIC50112.0 [1]
1-Adamantan-1-yl-3-(1-butyryl-piperidin-4-yl)-ureaIC502.64 [1]
1-(1-Adamantyl)-3-(1-methylsulfonylpiperidin-4-yl)ureaIC501.4 [1]
1-Cycloheptyl-3-(1-acetylpiperidin-4-yl)ureaIC5027.6 [1]
N-[[4-Bromo-2-(trifluoromethoxy)phenyl]methyl]-1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]piperidine-4-carboxamideIC5050000.0 [1]
N-[(2-Methylphenyl)carbamothioyl]acetamideIC501500.0 [1]
1-Adamantan-1-yl-3-(1-benzyl-piperidin-4-yl)-ureaIC508.4 [1]
1-(1-Adamantyl)-3-(3-phenylpropyl)ureaIC50100.0 [1]
1-Cyclohexyl-3-(4-methoxyphenyl)ureaIC50230.0 [1]
1-Cyclohexyl-3-(4-hydroxyphenyl)ureaIC5011100.0 [1]
1-Cyclohexyl-3-(4-hexylphenyl)ureaIC50160.0 [1]
N-(4-Chlorophenethyl)-3-methyl-3-phenylpiperidine-1-carboxamideIC5054000.0 [1]
3-Methyl-3-phenyl-N-(2-(quinoxalin-6-yl)ethyl)piperidine-1-carboxamideIC50100000.0 [1]
N-(4-Chlorophenyl)-3-(2-cyanoethyl)-3-phenylpiperidine-1-carboxamideIC50100000.0 [1]
4-(1-(4-Chlorophenylcarbamoyl)-3-phenylpiperidin-3-yl)butanoic acidIC50100000.0 [1]
3-(1-(4-Chlorophenylcarbamoyl)-3-phenylpiperidin-3-yl)propanoic acidIC50100000.0 [1]
N-(2-Phenylcyclopropyl)-4-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxamideIC50100000.0 [1]
N-[(1R,2S)-2-Phenylcyclopropyl]-4-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxamideIC50100000.0 [1]
4-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)-N-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-7-yl)piperidine-1-carboxamideIC50100000.0 [1]
4-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)-N-(1,2,3,4-tetrahydronaphthalen-2-yl)piperidine-1-carboxamideIC50100000.0 [1]
1-Adamantan-1-yl-3-(1-propionyl-piperidin-4-ylmethyl)-ureaIC508.7 [1]
1-Adamantan-1-yl-3-(1-butyryl-piperidin-4-ylmethyl)-ureaIC506.7 [1]
4-[4-(3-Adamantan-1-yl-ureido)-piperidine-1-carbonyl]-benzoic acidIC503.3 [1]
4-{4-[(3-Adamantan-1-yl-ureido)-methyl]-piperidin-1-yl}-4-oxo-butyric acid methyl esterIC506.2 [1]
5-{4-[(3-Adamantan-1-yl-ureido)-methyl]-piperidin-1-yl}-5-oxo-pentanoic acid methyl esterIC503.4 [1]
2-{4-[(3-Adamantan-1-yl-ureido)-methyl]-piperidine-1-carbonyl}-benzoic acid methyl esterIC501.8 [1]
3-{4-[(3-Adamantan-1-yl-ureido)-methyl]-piperidine-1-carbonyl}-benzoic acid methyl esterIC504.1 [1]
4-{4-[(3-Adamantan-1-yl-ureido)-methyl]-piperidine-1-carbonyl}-benzoic acid methyl esterIC501.5 [1]
2-[4-(3-Adamantan-1-yl-ureido)-piperidine-1-carbonyl]-benzoic acid methyl esterIC501.7 [1]
4-[4-(3-Adamantan-1-yl-ureido)-piperidine-1-carbonyl]-benzoic acid methyl esterIC501.1 [1]
4-[4-(3-Adamantan-1-yl-ureido)-piperidin-1-yl]-4-oxo-butyric acidIC50254.5 [1]
5-[4-(3-Adamantan-1-yl-ureido)-piperidin-1-yl]-5-oxo-pentanoic acidIC5072.8 [1]
1-Adamantan-1-yl-3-[1-(2,2,2-trifluoro-acetyl)-piperidin-4-ylmethyl]-ureaIC501.8 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Epoxide hydrolase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/epoxide-hydrolase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Epoxide hydrolase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/epoxide-hydrolase-1-inhibitors-ic50-ki.
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