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Ephrin type-B receptor 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
StaurosporineIC50198.8 [1]
HematoxylineIC5010000.0 [1]
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazoleIC507800.0 [1]
DasatinibIC504.4 [1]
CrizotinibIC5010000.0 [1]
1-Tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amineIC5052000.0 [1]
BosutinibIC508.5 [1]
N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amineIC5010200.0 [1]
DoramapimodIC50160.0 [1]
6,7-Dimethoxy-2-phenylquinoxalineIC50110000.0 [1]
TivozanibIC5017.5 [1]
4-[3-Hydroxyanilino]-6,7-dimethoxyquinazolineIC501200.0 [1]
N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxyquinazolin-4-amineIC508500.0 [1]
Src Kinase Inhibitor IIC5086000.0 [1]
N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamideIC50180000.0 [1]
3-(4-Dimethylaminobenzylidenyl)-2-indolinoneIC5027500.0 [1]
2-(4-Hydroxyanilino)naphthalene-1,4-dioneIC5038000.0 [1]
N-(3-Bromophenyl)-1H-imidazo[4,5-g]quinazolin-8-amineIC5022000.0 [1]
N-(3-Imidazol-1-ylpropyl)-7H-purin-6-amineIC505200.0 [1]
5-[1-Furan-2-yl-meth-(Z)-ylidene]-2-(4-methoxy-phenylamino)-thiazol-4-oneIC50230000.0 [1]
N-(Pyridin-2-ylmethyl)-9H-purin-6-amineIC50106000.0 [1]
CID 44478401IC501.2 [1]
4-N-(3-Bromophenyl)-7-N-methylquinazoline-4,7-diamineIC5034000.0 [1]
N'-(5-Chloro-1,3-benzodioxol-4-yl)-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamineIC5050.0 [1]
4-[(2-Morpholin-4-yl-7H-purin-6-yl)amino]benzenesulfonamideIC5010000.0 [1]
5-[(Z)-1-(3,4-Dimethoxyphenyl)methylidene]-2-(4-hydroxyanilino)-1,3-thiazol-4-oneIC50220000.0 [1]
N-(2-Methoxyphenyl)-2-[(5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]acetamideIC50136000.0 [1]
5-(2-Amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-tert-butylpyridine-3-sulfonamideIC5010000.0 [1]
2-[3-[3-Tert-butyl-5-[(2,3-dichlorophenyl)carbamoylamino]pyrazol-1-yl]phenyl]acetamideIC5082.0 [1]
3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolineIC5010000.0 [1]
5-Fluoro-2-[[(1S)-1-(5-fluoropyridin-2-yl)ethyl]amino]-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrileIC5010000.0 [1]
Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxylateIC5010000.0 [1]
1-(4-Fluorophenyl)-N-[3-fluoro-4-(5-phenylthieno[2,3-d]pyrimidin-4-yl)oxyphenyl]-2-oxopyridine-3-carboxamideIC5010000.0 [1]
1-[5-Tert-butyl-3-[4-[2-(dimethylamino)ethyl]-5-oxo-1,4-diazepane-1-carbonyl]thiophen-2-yl]-3-(2,3-dichlorophenyl)ureaIC507200.0 [1]
6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-oneIC5010000.0 [1]
2-Anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethylpyrrolo[2,3-d]pyrimidin-6-oneIC502158.0 [1]
CID 71718651IC503800.0 [1]
4-Chloro-N-(2-phenylimidazo[1,2-a]pyrimidin-3-yl)benzamideIC5088000.0 [1]
1-[3-[6-(4-Fluorophenyl)pyrazine-2-yloxy]phenyl]-3-(5-tert-butylisoxazole-3-yl)ureaIC502000.0 [1]
1-[3-[6-(p-Anisyl)pyrazine-2-yloxy]phenyl]-3-(5-tert-butylisoxazole-3-yl)ureaIC502000.0 [1]
1-[3-[6-(3-Thienyl)pyrazine-2-yloxy]phenyl]-3-(5-tert-butylisoxazole-3-yl)ureaIC502000.0 [1]
1-[3-[6-(1-Methyl-1H-pyrazole-4-yl)pyrazine-2-yloxy]phenyl]-3-(5-tert-butylisoxazole-3-yl)ureaIC50880.0 [1]
2-[3-[5-[(2,3-Dichlorophenyl)carbamoylamino]-3-thiophen-2-ylpyrazol-1-yl]phenyl]acetamideIC5050000.0 [1]
2-[3-(3-Piperidin-4-ylpropoxy)phenyl]-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamideKi2000.0 [1]
2-[3-(Methanesulfonamido)phenyl]-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamideKi2000.0 [1]
3-[2-(4-Amino-1-ethylpyrazolo[3,4-d]pyrimidin-3-yl)ethynyl]-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamideIC5026.0 [1]
1-[4-[6,7-Bis(trideuteriomethoxy)quinolin-4-yl]oxy-2-chlorophenyl]-3-(5-methyl-1,2-oxazol-3-yl)ureaIC5026.8 [1]
1-(5-Tert-butyl-1,2-oxazol-3-yl)-3-[3-[6-(4-methylsulfonylphenyl)pyrazin-2-yl]oxyphenyl]ureaIC502000.0 [1]
1-(3-Tert-butyl-1,2-oxazol-5-yl)-3-[4-[6-(1-methylpyrazol-4-yl)pyrazin-2-yl]phenyl]ureaIC502900.0 [1]
1-(5-Tert-butyl-2-methylpyrazol-3-yl)-3-[4-[6-(1-methylpyrazol-4-yl)pyrazin-2-yl]phenyl]ureaIC502200.0 [1]
6-[4-[(5-Tert-butyl-1,2-oxazol-3-yl)carbamoylamino]phenyl]-N-[3-(dimethylamino)propyl]imidazo[2,1-b][1,3]thiazole-3-carboxamideIC5010000.0 [1]
c-Met-IN-2IC5030000.0 [1]
3-(4-Methoxy-phenyl)-1-[2-(2-methyl-1H-indol-3-yl)-ethyl]-1-pyridin-4-ylmethyl-thioureaIC50250000.0 [1]
3-(4-Fluoro-phenyl)-1-[2-(2-methyl-1H-indol-3-yl)-ethyl]-1-pyridin-4-ylmethyl-thioureaIC50104000.0 [1]
3-(4-Chloro-phenyl)-1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)-ethyl]-1-pyridin-4-ylmethyl-thioureaIC5065000.0 [1]
3-[3-(2-Fluoro-phenyl)-[1,2,4]oxadiazol-5-yl]-N-(3-isopropoxy-propyl)-propionamideIC50201000.0 [1]
N-[5-[6-(Methylamino)pyrazin-2-yl]-2-oxo-1H-pyridin-3-yl]-4-[(2S)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]benzamideKi1000.0 [1]
2-[3-(3-Piperazin-1-ylpropoxy)phenyl]-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamideIC501000.0 [1]
3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethyl]sulfanyl-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amineIC501000.0 [1]
9-[[8-Fluoro-6-(1-methylpyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl]sulfanyl]-4-methyl-[1,4]oxazino[3,2-c]quinolin-3-oneIC5030000.0 [1]
N-[(E)-1-(2-Amino-4-methyl-1,3-thiazol-5-yl)ethylideneamino]-2-(benzenesulfonamido)-4-methyl-1,3-thiazole-5-carboxamideIC5094000.0 [1]
Items per page: 1 - 10 of 61
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References

This online tool may be cited as follows

MLA

"Quest Database™ Ephrin type-B receptor 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/ephrin-type-b-receptor-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 20). Quest Database™ Ephrin type-B receptor 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/ephrin-type-b-receptor-2-inhibitors-ic50-ki.
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