![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_e3bc3b69e81c4d3dedb7b80feffae961.svg) | Phosphoramidon | IC50 | 800.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_cbcd7c793123242d4d04892e4040357e.svg) | Thiorphan | IC50 | 8.0 [1], 100000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_cbcd7c793123242d4d04892e4040357e.svg) | Thiorphan | Ki | 10000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_2a98f077e8ba97a87c7564b61c49e6ff.svg) | (S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)ethylaminomethyl phosphonic acid | IC50 | 410.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_241c04a1eed86369d88509b6f36bd72a.svg) | (2S)-3-Dibenzofuran-3-yl-2-(phosphonomethylamino)propanoic acid | IC50 | 22.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_97c117c9af440979ffb3cbd525a010e8.svg) | 3-Biphenyl-4-yl-2-{[1-(2-mercapto-pentanoylamino)-cyclopentanecarbonyl]-amino}-propionic acid | IC50 | 11.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_f9e240362fc56fd9296ba8a1a98b8b94.svg) | [3-Naphthalen-1-yl-1-[[(1S)-2-(4-phenylphenyl)-1-(2H-tetrazol-5-yl)ethyl]amino]propyl]phosphonic acid | IC50 | 17.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_f9e240362fc56fd9296ba8a1a98b8b94.svg) | [3-Naphthalen-1-yl-1-[[(1S)-2-(4-phenylphenyl)-1-(2H-tetrazol-5-yl)ethyl]amino]propyl]phosphonic acid | Ki | 10.8 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c4c23c31e23becad907b67024d3d6ee1.svg) | (2S)-2-[[1-[[[(1R)-1-[[(2S)-6-Amino-2-(methanesulfonamido)hexanoyl]amino]-2-phenylethyl]-hydroxyphosphoryl]methyl]cyclopentanecarbonyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 70.0 [1], 80.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_705d394d940e91607dde0447d29f7c9f.svg) | 2-(4-Morpholinyl)-4H-1-benzopyran-4-one | IC50 | 12.0 [1], 67.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_787b66e2b0489b04c0ebe74d8b615c81.svg) | (2S)-2-[[1-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-(4-phenylphenyl)propanoic acid | IC50 | 77.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_10d0d112850756cf08611a7665e9b4c8.svg) | [[(S)-1-(2H-Tetrazole-5-yl)-4-(2-fluorophenyl)-3-butynyl]amino]methylphosphonic acid | IC50 | 150.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_9c5b8adbaa151f1f87f6b4452e905b1e.svg) | (2S)-2-[[(2S)-2-[[(2S)-5-(2,4-Difluorophenyl)-2-(phosphonomethylamino)pent-4-ynoyl]amino]-4-methylpentanoyl]amino]propanoic acid | IC50 | 8.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_085be93bb982d9293af7af915f76414e.svg) | 2-[5-(2,4-Difluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoylamino]-4-methyl-pentanoic acid | IC50 | 51.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_2edbfef380cce494c5b4f029c8b8e919.svg) | (2S)-2-[[(2R)-2-[(1R)-2,3-Dihydro-1H-inden-1-yl]-3-sulfanylpropanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | Ki | 26.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_9a8a29864b59bf00a0ff0f44432ccd5a.svg) | 2-(2-Indan-1-yl-3-mercapto-propionylamino)-3-(1H-indol-3-yl)-propionic acid | Ki | 100.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_2e055ad92c0675a0d82912d893839d1e.svg) | (2S)-3-(1H-Indol-3-yl)-2-[[(2R)-2-[(1S)-5-methoxy-2,3-dihydro-1H-inden-1-yl]-3-sulfanylpropanoyl]amino]propanoic acid | Ki | 10.0 [1], 180.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_066172730017aeadd9e61fbe6c447f40.svg) | 2-[[1-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-(4-pyrimidin-5-ylphenyl)propanoic acid | IC50 | 120.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_b6d39e9320bc6542d8231b9264419cb7.svg) | 2,3-Dihydro-1,4-benzodioxin-5-yl (2S,4R)-4-acetylsulfanyl-2-[(2,4,5-trifluorophenyl)methoxymethyl]pyrrolidine-1-carboxylate | IC50 | 6.9 [1], 76.5 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_ebaebcaf5ee43152438efae664dec917.svg) | 2-[[1-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 29.99 [1], 30.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_217207c3d1cfc0fd288524933fd2919c.svg) | 2,3-Dihydro-1,4-benzodioxin-5-yl (2S,4R)-4-benzoylsulfanyl-2-[(2,4,5-trifluorophenyl)methoxymethyl]pyrrolidine-1-carboxylate | IC50 | 49.7 [1], 480.5 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_3d02120b489d3abc93c1f7526bcae790.svg) | 2-[[1-[[(2R)-2-Sulfanylhexanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 55.98 [1], 56.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_d2abbde71ed07ddf74cfbdbfda7dd7ae.svg) | 2-[[1-[[(2S)-2-Sulfanylhexanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 23.99 [1], 24.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_7153049c8b563b204987b76fa11bd186.svg) | 2-[[1-[[(2S)-2-Sulfanylpentanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 26.98 [1], 27.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_61acaa697e823cc90b719334d80bf985.svg) | 2-[[1-[[(2R)-2-Sulfanylpentanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 82.0 [1], 82.04 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_63d3cb0b6d47f08bf9209686996a4ca2.svg) | 3-[6-(3-Acetamidophenyl)pyridin-3-yl]-2-[[1-[[(2S)-3-methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]propanoic acid | IC50 | 130.0 [1], 130.02 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c22da708d1314f9573f6acf1b0276020.svg) | 2-[[1-[[(2S)-4-Methyl-2-sulfanylpentanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 9.79 [1], 9.8 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_a48de001ddbb74b1bf633ba45c77607a.svg) | 2-[[1-[[(2S)-3-Cyclohexyl-2-sulfanylpropanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 23.0 [1], 23.01 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_77b17c6a1cef7786860d0a1e255f4aaa.svg) | 3-[6-(2-Methoxyphenyl)pyridin-3-yl]-2-[[1-[[(2S)-3-methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]propanoic acid | IC50 | 699.84 [1], 700.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_86089765b1618d4b5f59c3bd6dd6a715.svg) | 2-[[1-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-pyridin-3-ylpyridin-3-yl)propanoic acid | IC50 | 41.0 [1], 41.02 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_d3a1eaae36ffb531a56e68f8a8a25cc3.svg) | 2-[[1-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-phenylpyridin-3-yl)propanoic acid | IC50 | 76.91 [1], 77.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_18d1a59dafc61fefd13d8c03f0933dc8.svg) | 3-[6-(Furan-2-yl)pyridin-3-yl]-2-[[1-[[(2S)-3-methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]propanoic acid | IC50 | 42.95 [1], 43.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_cec56af15bb043c1bb1c19ed9fc3ae07.svg) | 2-[[1-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-[6-(3-nitrophenyl)pyridin-3-yl]propanoic acid | IC50 | 98.0 [1], 98.17 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_64627b97c8067bbd6680418ed54608ea.svg) | 2-[[1-[[(2S)-4-Methylsulfanyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-3-ylpyridin-3-yl)propanoic acid | IC50 | 54.95 [1], 55.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_83dc88d9780459f57b6e0d99233bb05f.svg) | 2-[[1-[[(2S)-3-Methyl-2-sulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-3-(6-thiophen-2-ylpyridin-3-yl)propanoic acid | IC50 | 48.98 [1], 49.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_a554f78470def7d4387205ed2fea7066.svg) | Methyl 2-[[2-[methyl-[(4R)-1-naphthalen-2-ylsulfonyl-4-sulfanylpyrrolidine-2-carbonyl]amino]acetyl]amino]benzoate | IC50 | 80.8 [1], 10890.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c54257c56f8f15af91f16f2de42b88bc.svg) | (4R)-N'-Methyl-N'-(4-methylphenyl)sulfonyl-1-naphthalen-2-ylsulfonyl-4-sulfanylpyrrolidine-2-carbohydrazide | IC50 | 61.3 [1], 2530.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c9c91490a8f66dad4950ae18016c01ee.svg) | Propan-2-yl (4R)-2-[[(2,5-difluorophenyl)methylamino]methyl]-4-sulfanylpyrrolidine-1-carboxylate | IC50 | 16.0 [1], 1090.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c0b816a53de6843ddf03d7111f576870.svg) | (3R)-5-[[(2,5-Difluorophenyl)methylamino]methyl]-1-(5-propylpyrimidin-2-yl)pyrrolidine-3-thiol | IC50 | 10.4 [1], 72.9 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_1acb8ec4228debb86bde533ba7d14ae0.svg) | [2-Naphthalen-2-yl-1-[[(1S)-2-(4-phenylphenyl)-1-(2H-tetrazol-5-yl)ethyl]amino]ethyl]phosphonic acid | IC50 | 45.0 [1], 20000.0 [2] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_7d4bb2f53887bffc73ff65aad54e92db.svg) | Captopril | Ki | 10000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_7bf8c82b7f581d8e9c85292e63e6e527.svg) | Actinonin | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_fe8749181f7d890f15e0913bd1e0afe7.svg) | Kelatorphan | IC50 | 8.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_090f2b7213061633b770d55ad23246b0.svg) | Sampatrilat | IC50 | 1500.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c52aa1a2a7966237ccf881ff0142af83.svg) | Unii-cdl03A411T | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c2b6f9dfc802bf7c837f24326a44415a.svg) | D-Tryptophan, N-[[5-[2-(4-methylphenyl)ethynyl]-2-thienyl]sulfonyl]- | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_84f2dac16c5f7de935d939ab0753c087.svg) | (2R)-2-[[1-[(5-Ethyl-1,3,4-thiadiazol-2-yl)carbamoyl]cyclopentyl]methyl]pentanoic acid | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_447bfebbace253eabc3b853620f7a86d.svg) | N-[(2r)-2-(Hydroxycarbamoyl)-4-Methylpentanoyl]-L-Alanylglycinamide | IC50 | 11.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_551325c1094fa0a038bbacfc015fc13c.svg) | (Inverted exclamation markA)-WS75624B | IC50 | 1300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_6253d2da46161fce87cb75f16dbf195c.svg) | (2S)-3-(4-Hydroxyphenyl)-2-[[(2R)-2-[[hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]methyl]-3-(3-phenyl-1,2-oxazol-5-yl)propanoyl]amino]propanoic acid | Ki | 14.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_5d5d89ca64c826558a3593135756e079.svg) | (2S)-2-[[(2R)-2-[(1S)-5-Bromo-2,3-dihydro-1H-inden-1-yl]-3-sulfanylpropanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | Ki | 90.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_b284768f89560007cc73e215d7d47258.svg) | 2-[3-Dibenzofuran-3-yl-2-(phosphonomethyl-amino)-propionylamino]-3-phenyl-propionic acid | IC50 | 23.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_bf21a6d81f55ee0a78c518505e27590e.svg) | 2-(3-Mercapto-5-methylhexanamido)-3-phenylpropanoic acid | IC50 | 10000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_e4fea82594b4c482e5bc503b02785304.svg) | (2S)-2-[[2-Benzyl-3-[hydroxy-[(1R)-2-phenyl-1-(phenylmethoxycarbonylamino)ethyl]phosphoryl]propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | Ki | 1.2 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_3b2a33d4a8ed723d870331b7eec8a6f3.svg) | N-Phosphorylleucyltryptophan | IC50 | 1500.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_d64ef40398186def2f0511d8f84f06da.svg) | (R)-2-[4-(4-Bromo-benzoylamino)-benzenesulfonylamino]-3-(1H-indol-3-yl)-propionic acid | IC50 | 1000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_f2e6e301b153d3d8de59fcbd05fb936f.svg) | 3-(2-Hydroxycarbamoylmethyl-3-methyl-butyrylamino)-propionic acid | IC50 | 190.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_8c66f29508b5ea9449d1de59130cc3e7.svg) | (2S)-2-[[(2S)-2-[[Cyclohexylmethyl(hydroxy)phosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 4800.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_89d80aaf849c75e84f1804544cfcbbae.svg) | (2S)-2-[[(2S)-2-[[Hydroxy(propyl)phosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 2000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_1c154249dd6d0a8dbea891523c18559a.svg) | (2S)-2-[[(2S)-2-[[Hydroxy(phenoxy)phosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 37000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_729b0e92b3c8898c76cce15ffce5c853.svg) | 3-[(4-Amino-4-oxo-2-propan-2-ylbutanoyl)amino]propanoic acid | IC50 | 6500.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_aaba11ebf972296f9ff7f8bbd6a460de.svg) | (6S)-4-Oxo-3-(sulfanylmethyl)-5-azabicyclo[11.3.1]heptadeca-1(16),13(17),14-triene-6-carboxylic acid | IC50 | 620.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_214fcd460a15d195e385111fe7e9917f.svg) | (2S)-2-[[(2S)-2-[[Hydroxy(propyl)phosphoryl]methyl]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_053c563ee40464f6a194a6beca40999b.svg) | (S)-2-((1-((5-Ethyl-1,3,4-thiadiazol-2-yl)carbamoyl)cyclopentyl)methyl)pentanoic acid | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_f3255a49230f2303f604f7cfa3d9b513.svg) | 3-(1H-Indol-3-yl)-2-[3-mercapto-2-(5-methoxy-indan-1-yl)-propionylamino]-propionic acid | Ki | 22.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c74695390e500062a6cd3ba27a910e2e.svg) | 2-[2-(5-Bromo-indan-1-yl)-3-mercapto-propionylamino]-3-(1H-indol-3-yl)-propionic acid | Ki | 31.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_cef69fef57efb75c05a51b9fabcbaff2.svg) | 3-(1H-Indol-3-yl)-2-[3-mercapto-2-(5-methylsulfanyl-indan-1-yl)-propionylamino]-propionic acid | Ki | 35.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_8bda0bdfe95e0c3eba6783335e19d0db.svg) | 5-[(3,3-Dimethylbutanoyl)amino]-1-(2-fluorobenzyl)-N~2~-phenyl-1H-indole-2-carboxamide | IC50 | 220.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_280c479823cb41750b67ff2b8d5b0f19.svg) | 2-(2-Hydroxycarbamoyl-3-methyl-butyrylamino)-succinamic acid | IC50 | 3.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_b88e3f14dcd13fcee7dc480367158b7a.svg) | 3-(2-Hydroxycarbamoyl-acetylamino)-propionic acid | IC50 | 3000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_124c3cccb74f478a0737b7e92e408d17.svg) | (2-Hydroxycarbamoyl-3-methyl-butyrylamino)-acetic acid | IC50 | 6.8 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_c963c0d28ff49990e5cb92f6cbdeb9fb.svg) | (2S)-2-[[(2S)-2-[[Ethoxy(hydroxy)phosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 109000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_86a1713a8d4c649e0ec4bb77f250142c.svg) | (2S)-2-[[(2S)-2-[[Benzyl(hydroxy)phosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 61000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_6523fa3f86bed444497554b8c259cc25.svg) | 3-(2-Hydroxycarbamoyl-3-methyl-butyrylamino)-propionic acid | IC50 | 0.01 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_d462d12d9f7d7e7ae2bdb246f8cc09d4.svg) | (2S)-2-[[(2S)-2-[Hydroxy(propyl)phosphoryl]oxy-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_ef56d844774811cdda16c1c4dd3b5b40.svg) | (2S)-2-[[(2S)-2-[Ethoxy(hydroxy)phosphoryl]oxy-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_a27466b0d0044e4bf35a0b0e3b0a8dc0.svg) | (2S)-3-(1H-Indol-3-yl)-2-[[(2R)-2-[(1R)-5-methoxy-2,3-dihydro-1H-inden-1-yl]-3-sulfanylpropanoyl]amino]propanoic acid | Ki | 10.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_d95d026a901affaa04110d089008876b.svg) | (2S)-2-[[(2S)-2-[[Cyclohexyloxy(hydroxy)phosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid | IC50 | 48000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_d5ffeb3a22b5c12338a8a7585b4e8d20.svg) | 5-Chloro-2-oxo-1,2,3,4-tetrahydroquinazoline-3-acetohydroxamic acid | IC50 | 10000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_95964ca46906c9474ee8f4c574ce82d8.svg) | (3R)-3-(Benzenesulfonyl)-N-hydroxyheptanamide | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_a5a12ca2b118f3aab760e0a2d15476dc.svg) | (S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoylamino]-3-methyl-butyric acid | IC50 | 110.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_868f14f8aabb782fad3930fb0725c3db.svg) | [[(2S)-5-(2,4-Difluorophenyl)-1-oxo-1-[2-(4-phenylphenyl)ethylamino]pent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 28.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_2e3f302b860c29f8062a9b7a31c58b8b.svg) | (S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoic acid | IC50 | 240.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_8663e480013cfba479efa3cd3dab2db5.svg) | [[(2S)-1-[2-(4-Bromophenyl)ethylamino]-5-(2-fluorophenyl)-1-oxopent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 110.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_003806f8e2d4e3b435e3361914b5d5b1.svg) | 3-Cyclohexanesulfonyl-heptanoic acid hydroxyamide | IC50 | 78000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_68c49bddce67bfc44cef090673fab78f.svg) | (2S)-2-[[(2S)-5-(2-Chlorophenyl)-2-(phosphonomethylamino)pent-4-ynoyl]amino]-4-methylpentanoic acid | IC50 | 4300.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_5f11ee24324f68af3708ec142b1c0888.svg) | (3S)-3-(Benzenesulfonyl)-N-hydroxyheptanamide | IC50 | 100000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_58e1b5d9074973ff9c88dacd411ac84f.svg) | [[2-(9-Methylcarbazol-2-yl)-1-(2H-tetrazol-5-yl)ethyl]amino]methylphosphonic acid | IC50 | 4000.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_8e116105da7c2e8eecf75b035be521ee.svg) | (S)-2-[(S)-5-(2-Fluoro-phenyl)-2-(phosphonomethyl-amino)-pent-4-ynoylamino]-3-phenyl-propionic acid | IC50 | 56.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_d089d4dcc708bc927eb5236d0e64f6ae.svg) | [[(2S)-5-(2-Fluorophenyl)-1-(2-naphthalen-1-ylethylamino)-1-oxopent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 130.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_dba48189d439987fc48e63c07bddc089.svg) | [[(2S)-5-(2,4-Difluorophenyl)-1-(2-naphthalen-1-ylethylamino)-1-oxopent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 34.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_08b9c391d3a6bf29faa9567429c7dabd.svg) | (2S)-5-(2-Fluorophenyl)-2-[[(2S)-5-(2-fluorophenyl)-2-(phosphonomethylamino)pent-4-ynoyl]amino]pent-4-ynoic acid | IC50 | 28.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_668ddba27ac3933fcddc8e2846a7febc.svg) | 3-Dibenzofuran-3-yl-2-[3-dibenzofuran-3-yl-2-(phosphonomethyl-amino)-propionylamino]-propionic acid | IC50 | 6.4 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_25c6da440f8f3e0b09ee837b93e9da1c.svg) | [[(2S)-5-(2,4-Difluorophenyl)-1-oxo-1-(2-pyridin-2-ylethylamino)pent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 310.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_7cc6aea821a4dbdf05a9d189e4b6c51a.svg) | {[(S)-4-(2,4-Difluoro-phenyl)-1-(3-methyl-butylcarbamoyl)-but-3-ynylamino]-methyl}-phosphonic acid | IC50 | 140.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_56dc720ed6d8e186abe72dee8d8c4749.svg) | [[(2S)-5-(2,4-Difluorophenyl)-1-oxo-1-(3-phenylpropylamino)pent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 150.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_46d795497029c215dc14a28e7ef2398f.svg) | [[(2S)-1-[2-(4-Bromophenyl)ethylamino]-5-(2,4-difluorophenyl)-1-oxopent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 43.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_2bf40417bfb7d767a96c1a999beddf00.svg) | {[(S)-1-Benzylcarbamoyl-4-(2-fluoro-phenyl)-but-3-ynylamino]-methyl}-phosphonic acid | IC50 | 250.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_4dd3cc98c5233914a543d3743425014d.svg) | [[(2S)-5-(2-Fluorophenyl)-1-oxo-1-[2-(4-phenylphenyl)ethylamino]pent-4-yn-2-yl]amino]methylphosphonic acid | IC50 | 33.0 [1] |
![](https://images.aatbio.com/dataset/ic50/endothelin-converting-enzyme-1_9bc1ca0cbdee5596c0ea6628991ffe16.svg) | 2-(5-Chloro-2,2-dioxo-1,4-dihydro-2lambda6,1,3-benzothiadiazin-3-yl)-N-hydroxyacetamide | IC50 | 10000.0 [1] |