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Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1,4-Dideoxy-1,4-imino-D-ribitolKi1260.0 [1]
(2R,3R,4S)-2-({[(1R)-2-Hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diolKi16810.0 [1]
(3R,4S)-Pyrrolidine-3,4-diolKi3240.0 [1]
(2R,3R,4S)-2-(Benzylamino-methyl)-pyrrolidine-3,4-diolKi35020.0 [1]
(2R,3R,4S)-2-(Aminomethyl)pyrrolidine-3,4-diolKi1590.0 [1]
(2R,3R,4S)-2-[[[(1R,2S)-2-Hydroxy-1,2-diphenylethyl]amino]methyl]pyrrolidine-3,4-diolKi790.0 [1]
(2R,3R,4S)-2-({[(1S)-2-Hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diolKi12040.0 [1]
(2R,3R,4S)-2-[[[(1S,2R)-2-Hydroxy-1,2-diphenylethyl]amino]methyl]pyrrolidine-3,4-diolKi2620.0 [1]
(2R,3R,4S)-2-[[[(1R)-1-Hydroxyethyl]amino]methyl]pyrrolidine-3,4-diolKi918320.0 [1]
(2R,3R,4S)-2-[[[(1S)-1-Hydroxyethyl]amino]methyl]pyrrolidine-3,4-diolKi487860.0 [1]
(2R,3R,4S)-2-(1,2-Dihydroxyethyl)pyrrolidine-3,4-diolKi168790.0 [1]
(2R,3R,4S)-2-[(Cyclopentylamino)methyl]pyrrolidine-3,4-diolKi66910.0 [1]
(2R,3R,4S)-2-[(Thiophen-2-ylmethylamino)methyl]pyrrolidine-3,4-diolKi77660.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-Methoxy-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi12140.0 [1]
(2R,3R,4S)-2-[[[(1R)-1-Phenyl-2-phenylmethoxyethyl]amino]methyl]pyrrolidine-3,4-diolKi230.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(3-Fluorophenyl)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi760.0 [1]
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[[[(1R)-2-hydroxy-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi24550.0 [1]
2-Bromo-N-[(2R)-2-[[(2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl]methylamino]-2-phenylethyl]benzamideKi160.0 [1]
(2R,3R,4S)-2-[(Imidazol-1-ylmethylamino)methyl]pyrrolidine-3,4-diolKi325870.0 [1]
(2R,3R,4S)-2-[(Furan-2-ylmethylamino)methyl]pyrrolidine-3,4-diolKi136130.0 [1]
(2R,3R,4S)-2-[[(1-Benzylpiperidin-4-yl)methylamino]methyl]pyrrolidine-3,4-diolKi13080.0 [1]
N-Benzyl-N-[[[(2R,3R,4S)-3,4-dihydroxypyrrolidin-2-yl]methylamino]methyl]acetamideKi44840.0 [1]
(2R,3R,4S)-2-(2,2-Dihydroxyethyl)pyrrolidine-3,4-diolKi286850.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(4-Bromophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi310.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(2-Fluorophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi910.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(4-Fluorophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi440.0 [1]
(2R,3R,4S)-2-[[[(1R)-2-[(3-Bromophenoxy)methoxy]-1-phenylethyl]amino]methyl]pyrrolidine-3,4-diolKi310.0 [1]
(2R,3R,4S)-2-[[(1-Hydroxy-1,1-diphenylpropan-2-yl)amino]methyl]pyrrolidine-3,4-diolKi27140.0 [1]
(2R,3R,4S)-2-[(1-Phenylethylamino)methyl]pyrrolidine-3,4-diolKi28100.0 [1]
(2R,3R,4S)-2-(2-Anilinoethyl)pyrrolidine-3,4-diolKi74310.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Nov2024https://www.aatbio.com/data-sets/endoplasmic-reticulum-mannosyl-oligosaccharide-1-2-alpha-mannosidase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 21). Quest Database™ Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/endoplasmic-reticulum-mannosyl-oligosaccharide-1-2-alpha-mannosidase-inhibitors-ic50-ki.
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