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Endoplasmic reticulum aminopeptidase 2 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
[(2S)-2-[[(2S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamoyl]-4-methylpentyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acidIC5011.0 [1], 50.0 [2], 80.0 [3]
Methyl N-[4-Amino-3-(L-Arginylamino)benzene-1-Carbonyl]-L-TyrosinateIC50518.0 [1], 2000.0 [2]
[(2S)-2-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4,4-diphenylbutyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acidIC50740.0 [1]
[(2S)-2-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]carbamoyl]-4,4-diphenylbutyl]-[(1R)-1-amino-3-phenylpropyl]phosphinic acidKi200.0 [1]
Leucine Phosphonic AcidKi250000.0 [1]
Phosphonic acid, (1-amino-3-phenylpropyl)-Ki250000.0 [1]
2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi350.0 [1]
2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-(4-hydroxyphenyl)propanoic acidKi1040.0 [1]
CID 118720630Ki152.0 [1]
CID 127052870Ki1680.0 [1]
[(1S)-1-Amino-3-methylbutyl]phosphonic acidKi250000.0 [1]
[1-Amino-2-(cyclohexylamino)ethyl]phosphonic acidKi8190.0 [1]
2-[[[1-Amino-3-(3,5-dimethylphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi7670.0 [1]
2-[[[1-Amino-3-(3-hydroxyphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi4570.0 [1]
2-[[[1-Amino-3-(4-hydroxyphenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi2180.0 [1]
2-[[[1-Amino-3-[4-(hydroxymethyl)phenyl]propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi185.0 [1]
2-[[(1-Amino-3-pyridin-3-ylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi205.0 [1]
2-[[(1-Amino-3-pyridin-4-ylpropyl)-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi241.0 [1]
2-[[(1-Amino-3-phenylpropyl)-hydroxyphosphoryl]methyl]-3-(3,5-dimethylphenyl)propanoic acidKi250000.0 [1]
2-[[3-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-phenylpropyl)-hydroxyphosphoryl]propanoic acidKi250000.0 [1]
2-[[4-(Aminomethyl)phenyl]methyl]-3-[(1-amino-3-phenylpropyl)-hydroxyphosphoryl]propanoic acidKi250000.0 [1]
(1-Amino-2-morpholin-4-ylethyl)phosphonic acidKi250000.0 [1]
2-[[[1-Amino-2-(2-methylpropylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi55300.0 [1]
2-[[[1-Amino-2-(cyclohexylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi7940.0 [1]
[1-Amino-2-(oxolan-2-ylmethylamino)ethyl]phosphonic acidKi250000.0 [1]
(1-Amino-2-piperidin-1-ylethyl)phosphonic acidKi622.0 [1]
[1-Amino-2-[(2-aminocyclohexyl)amino]ethyl]phosphonic acidKi10300.0 [1]
[1-Amino-2-(1-phenylethylamino)ethyl]phosphonic acidKi250000.0 [1]
[1-Amino-2-[2-(dimethylamino)ethylamino]ethyl]phosphonic acidKi250000.0 [1]
2-Benzyl-3-[1,2-diaminoethyl(hydroxy)phosphoryl]propanoic acidKi3020.0 [1]
[1-Amino-2-(cycloheptylamino)ethyl]phosphonic acidKi10600.0 [1]
[1-Amino-2-(2-phenylethylamino)ethyl]phosphonic acidKi1020.0 [1]
2-[[[1-Amino-2-(propylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi5540.0 [1]
[1-Amino-2-(2-piperazin-1-ylethylamino)ethyl]phosphonic acidKi7700.0 [1]
[1-Amino-2-[(4-tert-butylphenyl)methylamino]ethyl]phosphonic acidKi11500.0 [1]
[1-Amino-2-[(4-aminophenyl)methylamino]ethyl]phosphonic acidKi24900.0 [1]
2-[[[1-Amino-2-(cycloheptylamino)ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi9510.0 [1]
[1-Amino-2-[(4-methoxyphenyl)methylamino]ethyl]phosphonic acidKi8230.0 [1]
2-[[[1-Amino-2-[2-(4-methoxyphenyl)ethylamino]ethyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acidKi1300.0 [1]
[1-Amino-2-(hexylamino)ethyl]phosphonic acidKi632.0 [1]
[1-Amino-2-[[4-(aminomethyl)phenyl]methylamino]ethyl]phosphonic acidKi3470.0 [1]
[1-Amino-2-(piperidin-4-ylmethylamino)ethyl]phosphonic acidKi1420.0 [1]
[1-Amino-2-(benzylamino)ethyl]phosphonic acidKi106000.0 [1]
[1-Amino-2-(methylamino)ethyl]phosphonic acidKi250000.0 [1]
(1,2-Diaminoethyl)phosphonic acidKi16900.0 [1]
(2s)-3-[(S)-[(1r)-1-Amino-3-Phenylpropyl](Hydroxy)phosphoryl]-2-Benzylpropanoic AcidKi1030.0 [1]
N-Benzyl-2-[(4-fluorophenyl)methyl]-N'-hydroxypropanediamideIC50100000.0 [1]
Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]hexanoateIC5024900.0 [1]
CID 71817810IC508900.0 [1]
[(1r)-1-Amino-3-Phenylpropyl]phosphonic AcidKi47000.0 [1]
[1-Amino-2-(propylamino)ethyl]phosphonic acidKi250000.0 [1]
[1-Amino-2-(2-aminoethylamino)ethyl]phosphonic acidKi250000.0 [1]
Methyl 3-amino-4-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoateIC50100000.0 [1]
Methyl 4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoateIC50100000.0 [1]
4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoic acidIC503200.0 [1]
Methyl 4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoateIC509800.0 [1]
Methyl 4-amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoateIC503700.0 [1]
4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoic acidIC50100000.0 [1]
(2S)-6-Amino-2-[[4-amino-3-[[(2S)-2-amino-3-phenylpropanoyl]amino]benzoyl]amino]hexanoic acidIC502600.0 [1]
(2S)-6-Amino-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]hexanoic acidIC504500.0 [1]
Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]hexanoateIC504800.0 [1]
Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]hexanoateIC5013000.0 [1]
Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoyl]amino]hexanoateIC5052000.0 [1]
(2S)-6-Amino-2-[[4-amino-3-[[(2S)-2-amino-4-methylpentanoyl]amino]benzoyl]amino]hexanoic acidIC502100.0 [1]
Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]hexanoateIC508300.0 [1]
Methyl (2S)-6-amino-2-[[4-amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]hexanoateIC5017000.0 [1]
Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-methylbutanoateIC5050000.0 [1]
(2S)-2-[[4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-methylbutanoic acidIC50100000.0 [1]
Methyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoateIC5033000.0 [1]
Methyl (2S,3R)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-hydroxybutanoateIC5039000.0 [1]
Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoateIC5040000.0 [1]
(2S)-2-[[4-Amino-3-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acidIC50100000.0 [1]
Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoateIC50100000.0 [1]
(2S)-2-[[4-Amino-3-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acidIC50100000.0 [1]
Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoateIC50100000.0 [1]
(2S)-2-[[4-Amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-methylbutanoic acidIC50100000.0 [1]
Methyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoateIC506400.0 [1]
Benzyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoateIC501600.0 [1]
(2S)-2-[[4-Amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acidIC503800.0 [1]
Methyl (2S)-2-[[4-amino-3-[[(2S)-2-aminohexanoyl]amino]benzoyl]amino]-5-(diaminomethylideneamino)pentanoateIC502500.0 [1]
(2S)-2-[[4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]-3-methylbutanoic acidIC505000.0 [1]
(2S)-2-[[4-Amino-3-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acidIC50589.0 [1]
Methyl 3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoateIC5058000.0 [1]
Methyl 3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoateIC5058000.0 [1]
Methyl 3-amino-4-[[(2S)-2-aminohexanoyl]amino]benzoateIC501100.0 [1]
Methyl 3-amino-4-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]benzoateIC502500.0 [1]
Benzyl (2S)-2-[(3,4-diaminobenzoyl)amino]-3-(1H-indol-3-yl)propanoateIC50100000.0 [1]
(2S)-2-[(3,4-Diaminobenzoyl)amino]-3-(1H-indol-3-yl)propanoic acidIC501900.0 [1]
Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-methylbutanoateIC50100000.0 [1]
(2S)-2-[[3-Amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-methylbutanoic acidIC50100000.0 [1]
Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoateIC505500.0 [1]
Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoateIC5011000.0 [1]
Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-phenylbutanoyl]amino]benzoyl]amino]-5-(diaminomethylideneamino)pentanoateIC5011800.0 [1]
Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-phenylmethoxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoateIC5016000.0 [1]
Methyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(4-hydroxyphenyl)propanoateIC5015100.0 [1]
Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-3-(4-phenylmethoxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoateIC5020500.0 [1]
(2S)-2-[[3-Amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acidIC504800.0 [1]
Methyl (2S)-6-amino-2-[[3-amino-4-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]benzoyl]amino]hexanoateIC50100000.0 [1]
Benzyl (2S)-2-[[3-amino-4-[[(2S)-2-amino-4-(4-phenylmethoxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoateIC5070000.0 [1]
(2S)-2-[[3-Amino-4-[[(2S)-2-amino-4-(4-hydroxyphenyl)butanoyl]amino]benzoyl]amino]-3-(1H-indol-3-yl)propanoic acidIC509400.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Endoplasmic reticulum aminopeptidase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/endoplasmic-reticulum-aminopeptidase-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Endoplasmic reticulum aminopeptidase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/endoplasmic-reticulum-aminopeptidase-2-inhibitors-ic50-ki.
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