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EF-hand calcium-binding domain-containing protein 4B Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-2,3-difluorobenzamideIC5032.59 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-3-fluoropyridine-4-carboxamideIC5020.37 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]-4-methylthiadiazole-5-carboxamideIC5062.44 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]-4-methyl-1,3-thiazole-5-carboxamideIC50206.7 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]-5-methyl-1,2-oxazole-4-carboxamideIC50256.1 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]-2-methylbenzamideIC5036.35 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]-2-phenylacetamideIC50456.6 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]-2-pyridin-2-ylacetamideIC50968.1 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]-3-fluoropyridine-4-carboxamideIC50243.9 [1]
3,5-Dichloro-N-[4-(3,5-dicyclopropylpyrazol-1-yl)phenyl]pyridine-4-carboxamideIC50129.6 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)phenyl]pyridine-4-carboxamideIC50141.3 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)-3-fluorophenyl]-2,6-difluorobenzamideIC50145.1 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)-3-fluorophenyl]pyridine-4-carboxamideIC50184.6 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamideIC50183.6 [1]
N-[6-(3,5-Dicyclopropylpyrazol-1-yl)pyridin-3-yl]-2,6-difluorobenzamideIC50436.1 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-1,3-thiazole-5-carboxamideIC5072.03 [1]
3,5-Dichloro-N-[4-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]pyridine-4-carboxamideIC5065.49 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-5-methyl-1,2-oxazole-4-carboxamideIC5063.17 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-2-methylbenzamideIC50119.7 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-3,5-dimethyl-1,2-oxazole-4-carboxamideIC50124.5 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)-3-fluorophenyl]-4-methylpyrimidine-5-carboxamideIC50223.5 [1]
N-[4-(4-Chloro-3,5-dicyclopropylpyrazol-1-yl)-3-fluorophenyl]-4-methylthiadiazole-5-carboxamideIC50181.1 [1]
N-[4-(3,5-Dicyclopropylpyrazol-1-yl)-3-fluorophenyl]-4-methylthiadiazole-5-carboxamideIC5060.31 [1]
6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(2,6-difluorophenyl)pyridine-3-carboxamideIC5072.11 [1]
N-[4-[5-(Fluoromethyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-1,3-thiazole-5-carboxamideIC50373.4 [1]
N-[2-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyrimidin-5-yl]-2,6-difluorobenzamideIC50295.4 [1]
N-[4-[5-(Difluoromethyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-1,3-thiazole-5-carboxamideIC5052.62 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-2-methylbenzamideIC50147.2 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-5-methyl-1,2-oxazole-4-carboxamideIC5020.79 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-4-methyl-1,3-thiazole-5-carboxamideIC5048.17 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-2,6-difluorobenzamideIC5098.58 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]pyridine-4-carboxamideIC50254.7 [1]
1-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-3-(4-methyl-1,3-thiazol-5-yl)ureaIC50269.0 [1]
4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(4-methyl-1,3-thiazol-5-yl)benzamideIC5034.11 [1]
4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(2,6-difluorophenyl)benzamideIC50123.8 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-4-methylthiadiazole-5-carboxamideIC5035.72 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]pyridine-3-carboxamideIC50205.7 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]pyridine-4-carboxamideIC50232.0 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-3-fluoropyridine-4-carboxamideIC50159.1 [1]
3,5-Dichloro-N-[4-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]pyridine-4-carboxamideIC50159.3 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-4-methylpyrimidine-5-carboxamideIC5081.25 [1]
4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(2,6-difluorophenyl)-3-fluorobenzamideIC5099.71 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]-4-methylthiadiazole-5-carboxamideIC50149.6 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]-2-methylbenzamideIC5022.96 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]-2-fluorobenzamideIC5060.0 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]-2,3-difluorobenzamideIC5070.32 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]-2,6-difluorobenzamideIC5050.58 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]pyridine-3-carboxamideIC5047.21 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]pyridine-4-carboxamideIC5062.56 [1]
N-[6-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]pyridin-3-yl]-3-fluoropyridine-4-carboxamideIC5037.58 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-2-pyridin-3-ylacetamideIC5048.22 [1]
N-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-2-pyridin-2-ylacetamideIC50604.3 [1]
N-[4-[4-Chloro-5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methyl-1,3-thiazole-5-carboxamideIC50194.0 [1]
4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-N-[(4-methyl-1,3-thiazol-5-yl)methyl]anilineIC5048.02 [1]
1-[4-[5-Cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-3-fluorophenyl]-3-(4-methylpyrimidin-5-yl)ureaIC50600.3 [1]
N-[3-Amino-4-(3,5-dicyclopropylpyrazol-1-yl)phenyl]-4-methyl-1,3-thiazole-5-carboxamideIC50851.4 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ EF-hand calcium-binding domain-containing protein 4B Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/ef-hand-calcium-binding-domain-containing-protein-4b-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ EF-hand calcium-binding domain-containing protein 4B Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/ef-hand-calcium-binding-domain-containing-protein-4b-inhibitors-ic50-ki.
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