Ectonucleoside triphosphate diphosphohydrolase 2 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	CID 24949079	IC50	42000.0 [1]
	CID 24949079	Ki	8200.0 [1]
	(2S,3S,4R,5R)-N-[2-(Diethoxyphosphorylmethylamino)-2-oxoethyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	IC50	374000.0 [1]
	(2S,3S,4R,5R)-N-[2-(Diethoxyphosphorylmethylamino)-2-oxoethyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	Ki	71700.0 [1]
	(2S,3S,4R,5R)-N-[4-(Diethoxyphosphorylmethylamino)-4-oxobutyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	IC50	101000.0 [1]
	(2S,3S,4R,5R)-N-[4-(Diethoxyphosphorylmethylamino)-4-oxobutyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	Ki	29200.0 [1]
	8-[4-Methyl-3-[(5Z)-5-[(Z)-[5-[[2-methyl-5-[(4,6,8-trisulfo-2H-naphthalen-1-ylidene)carbamoyl]cyclohexa-2,4-dien-1-ylidene]carbamoyl]cyclohexa-2,4-dien-1-ylidene]carbamoyl]iminocyclohexa-1,3-diene-1-carbonyl]iminocyclohexa-1,4-diene-1-carbonyl]imino-7H-naphthalene-1,3,5-trisulfonic acid	IC50	24100.0 [1]
	Sodium 1-amino-9,10-dihydro-4-[(4-hydroxyphenyl)amino]-9,10-dioxoanthracene-2-sulphonate	Ki	200000.0 [1]
	[[[(2R,3S,4R,5R)-5-(6-Amino-2-hexylsulfanylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methylphosphonic acid	IC50	40000.0 [1]
	3,4,8-Tris(4-methylphenyl)-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3-Bromo-4-chloro-8-(4-methoxyphenyl)-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3,4,8-Tris(4-methoxyphenyl)-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3-Bromo-4-chloro-2-(trifluoromethyl)-8-[4-(trifluoromethyl)phenyl]quinoline	IC50	300000.0 [1]
	3,4,8-Triphenyl-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3-Bromo-4-chloro-8-thiophen-3-yl-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	4-Chloro-3,8-diphenyl-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3-[3-Bromo-4-chloro-2-(trifluoromethyl)quinolin-8-yl]benzonitrile	IC50	300000.0 [1]
	3,8-Dibromo-4-chloro-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3-Bromo-4-chloro-8-(2,5-dimethoxyphenyl)-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3,4,8-Tris(4-fluorophenyl)-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3,4,8-Tris(3-methylphenyl)-2-(trifluoromethyl)quinoline	IC50	300000.0 [1]
	3,8-Dibromo-2-(trifluoromethyl)-1H-quinolin-4-one	IC50	300000.0 [1]
	(2S,3S,4R,5R)-N-[3-(Diethoxyphosphorylmethylamino)-3-oxopropyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	Ki	167000.0 [1]
	(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-N-[4-[4-(diethoxyphosphorylmethyl)anilino]-4-oxobutyl]-3,4-dihydroxyoxolane-2-carboxamide	Ki	213000.0 [1]
	(2S,3S,4R,5R)-N-[3-[4-(Diethoxyphosphorylmethyl)anilino]-3-oxopropyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	Ki	173000.0 [1]
	(2S,3S,4R,5R)-N-[4-[4-(Diethoxyphosphorylmethyl)anilino]-4-oxobutyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	Ki	210000.0 [1]
	(2S,3S,4R,5R)-N-[2-(2-Diethoxyphosphorylethylamino)-2-oxoethyl]-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolane-2-carboxamide	Ki	116000.0 [1]
	(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-N-[3-[4-(diethoxyphosphorylmethyl)anilino]-3-oxopropyl]-3,4-dihydroxyoxolane-2-carboxamide	Ki	1440000.0 [1]
	2-[(4-Amino-9,10-dioxo-3-sulfoanthracen-1-yl)amino]-5-fluorobenzoic acid	Ki	200000.0 [1]
	1-Amino-4-(anthracen-2-ylamino)-9,10-dioxoanthracene-2-sulfonic acid	Ki	200000.0 [1]
	1-Amino-9,10-dioxo-4-(phenanthren-9-ylamino)anthracene-2-sulfonic acid	IC50	3000.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 31 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Ectonucleoside triphosphate diphosphohydrolase 2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/ectonucleoside-triphosphate-diphosphohydrolase-2-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ Ectonucleoside triphosphate diphosphohydrolase 2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/ectonucleoside-triphosphate-diphosphohydrolase-2-inhibitors-ic50-ki.
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