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E3 ubiquitin-protein ligase UHRF1 Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
(2-(Phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)IC5010000.0 [1], 30000.0 [2]
(5-Bromopyridin-3-yl)(4-(pyrrolidin-1-yl)piperidin-1-yl)methanoneIC5010000.0 [1], 30000.0 [2]
1,4-Phenylenebis(1,4'-bipiperidin-1'-ylmethanone)IC5010000.0 [1], 30000.0 [2]
1,4-Bis(4-(pyrrolidinyl)piperidinyl)benzamideIC5010000.0 [1]
1-Phenyl-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
4-(Pyrrolidin-1-Yl)-1-{4-[2-(Pyrrolidin-1-Yl)ethyl]phenyl}piperidineIC5030000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)furan-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[5-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)thiophen-2-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-(Benzylamino)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Benzyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Phenoxy-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Phenyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
2-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
3-Anilino-N-(2-ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(4-pyrrolidin-2-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
[3-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[2-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3,4-Bis(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylphenyl]methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-[(4-pyrrolidin-1-ylpiperidin-1-yl)methyl]phenyl]methanoneIC5010000.0 [1]
(4-Piperidin-1-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(Azepan-1-yl)piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(4-Morpholin-4-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Cyclohexylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpyrrolidin-1-ium-1-yl)piperidine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Piperidin-4-ylpiperidin-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(4-Cyclopentylpiperazine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpiperidin-4-yl)piperazine-1-carbonyl]phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[1-(4-Methylpiperazin-1-yl)ethyl]piperidin-1-yl]-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylazepan-1-yl)-[4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[4-(3-Pyrrolidin-1-ylazetidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[4-(3-pyrrolidin-1-ylpyrrolidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)-N-(3-pyrrolidin-1-ylpropyl)benzamideIC5010000.0 [1]
[4-(2,7-Diazaspiro[3.4]octane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,7-Diazaspiro[4.4]nonane-2-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,8-Diazaspiro[4.5]decane-8-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(2,3,3a,4,6,6a-Hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(2-Methyl-3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-7-yl)-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)benzamideIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylazepane-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylazepan-1-yl)methanoneIC5010000.0 [1]
[4-[4-(Azetidin-1-yl)piperidine-1-carbonyl]phenyl]-[4-(azetidin-1-yl)piperidin-1-yl]methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-2-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-2-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-[4-(1-Methylpyrrolidin-2-yl)piperidine-1-carbonyl]phenyl]-[4-(1-methylpyrrolidin-2-yl)piperidin-1-yl]methanoneIC5010000.0 [1]
[4-[4-(Dimethylamino)piperidine-1-carbonyl]phenyl]-[4-(dimethylamino)piperidin-1-yl]methanoneIC5010000.0 [1]
[6-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)pyridin-3-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Nitro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[3-Amino-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
(4-Pyrrolidin-1-ylpiperidin-1-yl)-[2,3,5,6-tetrafluoro-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]methanoneIC5010000.0 [1]
[2,5-Dimethyl-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(4-Pyrrolidin-1-ylpiperidine-1-carbonyl)naphthalen-1-yl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
N-(2-Ethyl-1,3-dihydroisoindol-5-yl)-4-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)benzamideIC5010000.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
[4-(8-Pyrrolidin-1-yl-3-azabicyclo[3.2.1]octane-3-carbonyl)phenyl]-(8-pyrrolidin-1-yl-3-azabicyclo[3.2.1]octan-3-yl)methanoneIC5010000.0 [1]
[3-Bromo-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanoneIC5010000.0 [1]
7-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-1,4-dioxa-7-azaspiro[4.4]nonaneIC5030000.0 [1]
6-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]-2-oxa-6-azaspiro[3.3]heptaneIC5030000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]pyrrolidine-3-carbonitrileIC5030000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azepaneIC5030000.0 [1]
1-[3-Chloro-4-(2-pyrrolidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
4-Piperidin-1-yl-1-[4-(2-pyrrolidin-1-ylethyl)phenyl]piperidineIC5030000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(3-pyrrolidin-1-ylpropyl)phenyl]piperidineIC5030000.0 [1]
4-Pyrrolidin-1-yl-1-[3-(2-pyrrolidin-1-ylethyl)phenyl]piperidineIC5030000.0 [1]
[3-(Hydroxymethyl)-1-[2-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]azetidin-3-yl]methanolIC5030000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(pyrrolidin-1-ylmethyl)phenyl]piperidineIC5030000.0 [1]
1-[[4-(2-Pyrrolidin-1-ylethyl)phenyl]methyl]pyrrolidineIC5030000.0 [1]
4-Pyrrolidin-1-yl-1-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]piperidineIC5030000.0 [1]
4-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]morpholineIC5030000.0 [1]
1-[4-[2-(Azetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
1-[4-[2-(3,3-Difluoroazetidin-1-yl)ethyl]phenyl]-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
1-[4-(2-Piperidin-1-ylethyl)phenyl]-4-pyrrolidin-1-ylpiperidineIC5030000.0 [1]
4-Pyrrolidin-1-yl-1-[3-(pyrrolidin-1-ylmethyl)phenyl]piperidineIC5030000.0 [1]
1-Pyrrolidin-1-yl-3-[4-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]propan-1-oneIC5030000.0 [1]
Pyrrolidin-1-yl-[3-(4-pyrrolidin-1-ylpiperidin-1-yl)phenyl]methanoneIC5030000.0 [1]
1-[2-[4-(4-Pyrrolidin-1-ylpiperidin-1-yl)phenyl]ethyl]pyrrolidin-3-oneIC5030000.0 [1]
Items per page: 1 - 10 of 78
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References

This online tool may be cited as follows

MLA

"Quest Database™ E3 ubiquitin-protein ligase UHRF1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/e3-ubiquitin-protein-ligase-uhrf1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ E3 ubiquitin-protein ligase UHRF1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/e3-ubiquitin-protein-ligase-uhrf1-inhibitors-ic50-ki.
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