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Dynamin-2 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
N-[2-[(7,8-Dihydroxy-2-iminochromene-3-carbonyl)amino]ethyl]-7,8-dihydroxy-2-iminochromene-3-carboxamideIC50440.0 [1], 1300000.0 [2]
2-N-Cyclohexyl-4-N-[2-(dimethylamino)ethyl]-6-methylpyrimidine-2,4-diamineIC501800.0 [1], 65900.0 [2]
N-[3-[(7,8-Dihydroxy-2-iminochromene-3-carbonyl)amino]propyl]-7,8-dihydroxy-2-iminochromene-3-carboxamideIC50390.0 [1], 10700.0 [2]
N-[3-[(6,7-Dihydroxy-2-iminochromene-3-carbonyl)amino]propyl]-6,7-dihydroxy-2-iminochromene-3-carboxamideIC50290.0 [1], 74600.0 [2]
2-N-[2-(Dimethylamino)ethyl]-4-N-hexyl-6-methylpyrimidine-2,4-diamineIC504000.0 [1], 31000.0 [2]
2-N-Dodecyl-4-N,4-N,6-trimethylpyrimidine-2,4-diamineIC501300.0 [1], 37800.0 [2]
4-N-[2-(Dimethylamino)ethyl]-6-N-dodecylpyrimidine-4,6-diamineIC508300.0 [1], 8500.0 [2]
6-N-Decyl-4-N-[2-(dimethylamino)ethyl]pyrimidine-4,6-diamineIC501800.0 [1], 6000.0 [2]
4-N-Decyl-2-N-[2-(dimethylamino)ethyl]-6-methylpyrimidine-2,4-diamineIC501600.0 [1], 5100.0 [2]
8-Hydroxy-N-[3-[(8-hydroxy-2-iminochromene-3-carbonyl)amino]propyl]-2-iminochromene-3-carboxamideIC5034800.0 [1], 48200.0 [2]
Dynole 34-2IC505000.0 [1]
4-Chloro-2-[[2-[4-(hydroxymethyl)phenyl]-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acidIC5040000.0 [1]
7-Hydroxy-N-[3-[(7-hydroxy-2-iminochromene-3-carbonyl)amino]propyl]-2-iminochromene-3-carboxamideIC5016700.0 [1]
4-N-[2-(Dimethylamino)ethyl]-2-N-hexyl-6-methylpyrimidine-2,4-diamineIC5047400.0 [1]
2-N-[2-(Dimethylamino)ethyl]-6-methyl-4-N-tetradecylpyrimidine-2,4-diamineIC5012900.0 [1]
4-N-Decyl-2-N-[2-(dimethylamino)ethyl]pyrimidine-2,4-diamineIC503700.0 [1]
2-N-[2-(Dimethylamino)ethyl]-6-methyl-4-N-octylpyrimidine-2,4-diamineIC508700.0 [1]
4-N-[2-(Dimethylamino)ethyl]-6-methyl-2-N-octylpyrimidine-2,4-diamineIC5010300.0 [1]
2-N-[2-(Dimethylamino)ethyl]-4-N-dodecylpyrimidine-2,4-diamineIC506100.0 [1]
4-Chloro-2-[[2-(2-hydroxyphenyl)-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acidIC5071000.0 [1]
4-Chloro-2-[[2-(4-hydroxyphenyl)-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acidIC50114000.0 [1]
4-Chloro-2-{[2-(3-nitrophenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carbonyl]-amino}-benzoic AcidIC5063000.0 [1]
(E)-2-Cyano-3-[1-[3-(dimethylamino)-2-hydroxypropyl]indol-3-yl]-N-octylprop-2-enamideIC503500.0 [1]
N-[[1-[3-(Dimethylamino)propyl]indol-3-yl]methyl]octan-1-amineIC503500.0 [1]
N-[[1-[3-(Dimethylamino)propyl]indol-3-yl]methyl]decan-1-amineIC501900.0 [1]
N-[[1-[3-(Dimethylamino)propyl]indol-3-yl]methyl]dodecan-1-amineIC502800.0 [1]
N-[[1-[3-(Dimethylamino)propyl]indol-3-yl]methyl]tetradecan-1-amineIC506800.0 [1]
(E)-2-Cyano-3-[1-(2-hydroxy-3-pyrrolidin-1-ylpropyl)-2-methylindol-3-yl]-N-octylprop-2-enamideIC504500.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Dynamin-2 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.21 Dec2024https://www.aatbio.com/data-sets/dynamin-2-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024December 21). Quest Database™ Dynamin-2 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dynamin-2-inhibitors-ic50-ki.
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