Dual specificity protein kinase CLK3 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	Silmitasertib	IC50	41.0 [1]
	9H-Purine-2,6-diamine, N2-(2-aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-, cis-	IC50	1000.0 [1]
	Cdk1/2 Inhibitor III	IC50	29.2 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(thiophen-2-ylmethyl)-4-quinazolinamine	IC50	6936.0 [1]
	CID 46926514	IC50	10000.0 [1]
	Ethyl 3-[(E)-2-Amino-1-Cyanoethenyl]-6,7-Dichloro-1-Methyl-1h-Indole-2-Carboxylate	IC50	530.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(2-furanylmethyl)-N-methyl-4-quinazolinamine	IC50	8744.0 [1]
	[5-[4-[(5-Methyl-2-furanyl)methylamino]-6-quinazolinyl]-2-furanyl]methanol	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[(2-methyl-4-thiazolyl)methyl]-4-quinazolinamine	IC50	7448.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-[(2-methyl-4-thiazolyl)methyl]-4-quinazolinamine	IC50	1924.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-(1,3-thiazol-2-ylmethyl)quinazolin-4-amine	IC50	4655.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-(thiophen-2-ylmethyl)-4-quinazolinamine	IC50	4949.0 [1]
	6-(Benzo[d][1,3]dioxol-5-yl)-N-(furan-3-ylmethyl)quinazolin-4-amine	IC50	4650.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(3-oxolanylmethyl)-4-quinazolinamine	IC50	3642.0 [1]
	CID 46926513	IC50	10000.0 [1]
	(Z)-3-Pyridin-3-yl-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-enenitrile	IC50	10000.0 [1]
	6-(2,4-Difluorophenyl)sulfonyl-2-(1H-indol-5-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one	IC50	10000.0 [1]
	2-[3-(3-Piperidin-4-ylpropoxy)phenyl]-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamide	Ki	2000.0 [1]
	(5Z)-5-(Quinolin-6-ylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one	IC50	86.6 [1]
	2-[3-(Methanesulfonamido)phenyl]-N-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-yl]acetamide	Ki	2000.0 [1]
	11H-Pyrido[3,4-a]carbazole-6-carbonitrile	IC50	1800.0 [1]
	Clk1-IN-1	IC50	5590.0 [1]
	N-(4-Morpholin-4-ylcyclohexyl)-5-(oxan-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-2-N-[(3R)-piperidin-3-yl]-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-2-N-[(1R,2S)-2-aminocyclohexyl]-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	N-[3-[[2-[[(1R,2S)-2-Aminocyclohexyl]amino]-9-propan-2-ylpurin-6-yl]amino]-5-chlorophenyl]acetamide	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-2-N-[(1S,2S)-2-aminocyclohexyl]-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-2-N-[(1R,2R)-2-aminocyclohexyl]-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	N-[3-[[2-[[(1S,2R)-2-Aminocyclohexyl]amino]-9-propan-2-ylpurin-6-yl]amino]-5-chlorophenyl]acetamide	IC50	1000.0 [1]
	2-N-[(1S,2R)-2-Aminocyclohexyl]-6-N-(3-chlorophenyl)-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	2-N-[(1R,2R)-2-Aminocyclohexyl]-6-N-(3-chlorophenyl)-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	2-N-[(1S,2S)-2-Aminocyclohexyl]-6-N-(3-chlorophenyl)-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-2-N-[(1S,2R)-2-aminocyclohexyl]-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	2-N-[(1R,2S)-2-Aminocyclohexyl]-6-N-(3-chlorophenyl)-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-9-propan-2-yl-2-N-[(3S)-pyrrolidin-3-yl]purine-2,6-diamine	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-2-N-[(3S)-piperidin-3-yl]-9-propan-2-ylpurine-2,6-diamine	IC50	1000.0 [1]
	6-N-(3-Amino-5-chlorophenyl)-9-propan-2-yl-2-N-[(3R)-pyrrolidin-3-yl]purine-2,6-diamine	IC50	1000.0 [1]
	1-[4-[4-[[5-(Oxan-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]amino]cyclohexyl]piperazin-1-yl]ethanone	IC50	10000.0 [1]
	1-[4-[4-[(5-Propan-2-ylpyrrolo[2,1-f][1,2,4]triazin-4-yl)amino]cyclohexyl]piperazin-1-yl]ethanone	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[(3-methylthiophen-2-yl)methyl]quinazolin-4-amine	IC50	6555.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[2-(1H-imidazol-5-yl)ethyl]quinazolin-4-amine	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(2-oxolanylmethyl)-4-quinazolinamine	IC50	3294.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-[(5-methyl-1,3,4-oxadiazol-2-yl)methyl]quinazolin-4-amine	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[2-(2-furanyl)ethyl]-4-quinazolinamine	IC50	2017.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[(5-methylfuran-2-yl)methyl]quinazolin-4-amine	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(1H-imidazol-2-ylmethyl)quinazolin-4-amine	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[(5-methylthiophen-2-yl)methyl]quinazolin-4-amine	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-[(2-methyl-3-furanyl)methyl]-4-quinazolinamine	IC50	6450.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-[(3-methylthiophen-2-yl)methyl]quinazolin-4-amine	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-ethyl-N-(thiophen-2-ylmethyl)-4-quinazolinamine	IC50	6172.0 [1]
	Ethyl 5-(4-(thiophen-2-ylmethylamino)quinazolin-6-yl)furan-2-carboxylate	IC50	10000.0 [1]
	Ethyl 5-(4-((5-methylfuran-2-yl)methylamino)quinazolin-6-yl)furan-2-carboxylate	IC50	10000.0 [1]
	6-(3-Furanyl)-N-methyl-N-[(3-methyl-2-thiophenyl)methyl]-4-quinazolinamine	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(1H-imidazol-2-ylmethyl)-N-methylquinazolin-4-amine	IC50	10000.0 [1]
	(5-(4-(Methyl((3-methylthiophen-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol	IC50	10000.0 [1]
	5-(4-((5-Methylfuran-2-yl)methylamino)quinazolin-6-yl)furan-2-carboxylic acid	IC50	10000.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(2-thiazolylmethyl)-4-quinazolinamine	IC50	3527.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-methyl-N-[(4-methyl-1,3-thiazol-2-yl)methyl]quinazolin-4-amine	IC50	3019.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(2,2-dimethylpropyl)quinazolin-4-amine	IC50	435.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(furan-2-ylmethyl)quinazolin-4-amine	IC50	2556.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(cyclopentylmethyl)-4-quinazolinamine	IC50	1320.0 [1]
	6-(1,3-Benzodioxol-5-yl)-N-(3-oxanylmethyl)-4-quinazolinamine	IC50	5461.0 [1]
	4-(1,3-Benzodioxol-5-yl)-N-[3-(trifluoromethyl)phenyl]pyrimidin-2-amine	IC50	10000.0 [1]
	4-(1,3-Benzodioxol-5-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amine	IC50	1473.0 [1]
	N-[(3,4-Dichlorophenyl)methyl]-4-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimidin-2-amine	IC50	10000.0 [1]
	4-(1,3-Benzodioxol-5-yl)-N-[(3,4-dichlorophenyl)methyl]pyrimidin-2-amine	IC50	3634.0 [1]
	4-(1,3-Benzodioxol-5-yl)-N-[(3,4-dibromophenyl)methyl]pyrimidin-2-amine	IC50	3232.0 [1]
	4-(1H-Indazol-5-yl)-N-(pyridin-3-ylmethyl)pyrimidin-2-amine	IC50	2663.0 [1]
	N-[(3,4-Dichlorophenyl)methyl]-4-(1H-indazol-5-yl)pyrimidin-2-amine	IC50	2934.0 [1]
	N2-[(1R,2S)-2-Aminocyclohexyl]-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine	IC50	1000.0 [1]
	N-(2,2-Dimethylpropyl)-6-[5-(ethylaminomethyl)furan-2-yl]quinazolin-4-amine	IC50	10000.0 [1]
	2-N-[(1S,2S)-2-Aminocyclohexyl]-6-N-(3-chlorophenyl)-9-ethylpurine-2,6-diamine	IC50	1000.0 [1]
	2-[3-(3-Piperazin-1-ylpropoxy)phenyl]-N-(4-pyridin-4-yl-1,3-thiazol-2-yl)acetamide	IC50	1000.0 [1]
	(9-Methoxy-11H-pyrido[4,3-a]carbazol-6-yl)methanamine	IC50	7000.0 [1]
	(Z)-2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-3-pyridin-3-ylprop-2-enenitrile	IC50	10000.0 [1]
	9-Methoxy-11H-pyrido[4,3-a]carbazole-6-carbonitrile	IC50	190.0 [1]
	1,9-Dimethoxy-11H-pyrido[4,3-a]carbazole-6-carbonitrile	IC50	320.0 [1]
	N-[(9-Methoxy-11H-pyrido[4,3-a]carbazol-6-yl)methyl]acetamide	IC50	8000.0 [1]
	10-Methoxy-11H-pyrido[4,3-a]carbazole-6-carbonitrile	IC50	180.0 [1]
	8-Fluoro-11H-pyrido[4,3-a]carbazole-6-carbonitrile	IC50	10000.0 [1]
	7-Methoxy-11H-pyrido[4,3-a]carbazole-6-carbonitrile	IC50	10000.0 [1]
	10-Methoxy-11H-pyrido[4,3-a]carbazole-6-carboxamide	IC50	6100.0 [1]
	8-Methoxy-11H-pyrido[4,3-a]carbazole-6-carbonitrile	IC50	710.0 [1]
	N-[7-(5-Methoxy-1H-indol-3-yl)isoquinolin-6-yl]acetamide	IC50	7000.0 [1]
	6-Methoxy-3-pyridin-4-yl-1H-pyrrolo[2,3-b]pyridine	IC50	6100.0 [1]
	6-Methoxy-1-oxo-3-pyridin-3-yl-2,9-dihydropyrido[3,4-b]indole-4-carbonitrile	IC50	10000.0 [1]
	14-Methoxy-5,15,17-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1,3,5,7,9,11(16),12,14-octaene-9-carbonitrile	IC50	10000.0 [1]
	5,15,17-Triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1,3,5,7,9,11(16),12,14-octaene-9-carbonitrile	IC50	6800.0 [1]
	6,10-Dihydroxy-11-methoxy-3,3-dimethyl-12H-pyrano[2,3-c]acridin-7-one	IC50	2300.0 [1]
	Ethyl 3-[(Z)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methylindole-2-carboxylate	IC50	530.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 90 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ Dual specificity protein kinase CLK3 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Dec. 2024, https://www.aatbio.com/data-sets/dual-specificity-protein-kinase-clk3-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2024, December 21). Quest Database™ Dual specificity protein kinase CLK3 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dual-specificity-protein-kinase-clk3-inhibitors-ic50-ki.
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