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Dual specificity phosphatase Cdc25C Inhibitors (IC50, Ki)

Structure
▲
▼
Compound Name
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▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
MenadioneIC5018800.0 [1], 19000.0 [2]
2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedioneIC5056.9 [1], 78.0 [2]
6-Chloro-7-{[2-(morpholin-4-yl)ethyl]amino}quinoline-5,8-dioneIC50250.0 [1]
6-Chloro-7-{[2-(morpholin-4-yl)ethyl]amino}quinoline-5,8-dioneKi89.0 [1]
4-Heptadecyl-2,5-dihydro-2,5-dioxofuran-3-propionic acidIC504300.0 [1]
2,5-Dihydroxy-3-[7-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dioneIC503500.0 [1]
2,5-Dihydroxy-3-[7-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dioneKi640.0 [1]
5-[2-(4-Ethoxyphenyl)-1,3-thiazol-4-yl]-2,3-dihydro-1H-1,3-benzodiazol-2-oneIC5010200.0 [1], 47300.0 [2]
1-Methanesulfonyl-5-[2-(3-methylphenyl)-1,3-thiazol-4-yl]-2,3-dihydro-1H-indoleIC5024300.0 [1], 37800.0 [2]
4-{2,5-Dimethyl-1-[(oxolan-2-yl)methyl]-1H-pyrrol-3-yl}-2-(4-methoxyphenyl)-1,3-thiazoleIC5024700.0 [1], 100000.0 [2]
2-(4-Ethoxyphenyl)-4-(naphthalen-2-yl)-1,3-thiazoleIC5031500.0 [1], 71500.0 [2]
N-[3-(2-Phenyl-1,3-thiazol-4-yl)phenyl]-2-furamideIC50100000.0 [1]
N-{3-[4-(4-Methoxyphenyl)-1,3-thiazol-2-yl]phenyl}cyclopropanecarboxamideIC5016800.0 [1], 42200.0 [2]
2-(4-Methoxyphenyl)-4-(1-methylsulfonyl-2,3-dihydroindol-5-yl)-1,3-thiazoleIC5018000.0 [1], 42500.0 [2]
1-Methanesulfonyl-5-[2-(2-methoxyphenyl)-1,3-thiazol-4-yl]-2,3-dihydro-1H-indoleIC5014200.0 [1], 42600.0 [2]
5-[2-(4-Ethoxyphenyl)-1,3-thiazol-4-yl]-1-methyl-2,3-dihydro-1H-indol-2-oneIC5047600.0 [1], 100000.0 [2]
7-((2-(3,5-Dibromo-4-hydroxyphenyl)ethyl)amino)-5,8-quinolinedioneIC5035000.0 [1]
4,7-Benzothiazoledione, 5-((2-(dimethylamino)ethyl)amino)-2-methyl-IC50150.0 [1]
3-Benzoylnaphtho[1,2-b]furan-4,5-dioneIC505000.0 [1]
N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]pyrazine-2-carboxamideIC5040000.0 [1]
2-[4-[2-Acetamido-3-[[5-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-5-oxopentyl]amino]-3-oxopropyl]-2-ethyl-N-oxaloanilino]benzoic acidKi300000.0 [1]
2-[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxo-2-(prop-2-enoxycarbonylamino)propyl]-N-oxaloanilino]benzoic acidKi178000.0 [1]
2-[[4-[2-Acetamido-3-oxo-3-(pentylamino)propyl]naphthalen-1-yl]-oxaloamino]benzoic acidKi300000.0 [1]
[5-(5-Cyano-1-methylene-pentyl)-1-(1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-4-yl]-acetic acidIC506500.0 [1]
Maleimide analogIC5040000.0 [1]
2-[(7-Methoxy-2-oxochromen-4-yl)methylsulfanyl]naphthalene-1,4-dioneIC509000.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(3-methylphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC50100000.0 [1]
4-(Biphenyl-4-yl)thiazole-2-ylmethyl 2-furylmethyl sulfoneIC509700.0 [1]
3-Methoxy-N,N,4-trimethyl-5-[[methyl-[2-(4-nitrophenyl)ethyl]amino]methyl]anilineIC505400.0 [1]
2-[4-[2-Acetamido-3-[4-(5-chloro-3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-3-oxopropyl]-2-ethyl-N-oxaloanilino]benzoic acidKi3000.0 [1]
3-(1,3-Benzodioxol-5-yl)-N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]acrylamideIC5011000.0 [1]
3-[4,6-Dichloro-7-(3-methylbut-2-enyl)-1H-indol-3-yl]-2,5-dihydroxycyclohexa-2,5-diene-1,4-dioneIC508800.0 [1]
5-[2-(Dimethylamino)ethylamino]-2-phenyl-1,3-benzoxazole-4,7-dioneIC50230.0 [1]
6-[2-(Dimethylamino)ethylamino]-2-phenyl-1,3-benzoxazole-4,7-dioneIC50230.0 [1]
2-(1-Carboxyethoxy)-5-[(2S)-3-[4-(3-hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-3-oxopropyl]benzoic acidKi30000.0 [1]
Methylbenzyl(4-nitrophenethyl)amineIC5080000.0 [1]
3-(1H-Benzo[g]indol-3-yl)-2,5-dihydroxycyclohexa-2,5-diene-1,4-dioneIC5015000.0 [1]
3-(4-Chloro-1H-indol-3-yl)-2,5-dihydroxycyclohexa-2,5-diene-1,4-dioneIC5050000.0 [1]
3-[6-Chloro-7-(3-methylbut-2-enyl)-1H-indol-3-yl]-2,5-dihydroxycyclohexa-2,5-diene-1,4-dioneIC5011000.0 [1]
2,5-Dihydroxy-3-(7-phenylmethoxy-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dioneIC506900.0 [1]
2,5-Dihydroxy-3-(7-propyl-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dioneIC5050000.0 [1]
3-(7-Tert-butyl-1H-indol-3-yl)-2,5-dihydroxycyclohexa-2,5-diene-1,4-dioneIC5050000.0 [1]
3-(2-Cyclopropyl-1H-indole-3-yl)-2,5-dihydroxy-p-benzoquinoneIC5050000.0 [1]
2,5-Dioxo-4-hexylfuran-3-propanoic acidIC50100000.0 [1]
2,5-Dioxo-4-octylfuran-3-propanoic acidIC50100000.0 [1]
4-Dimethylamino-2-{[2-(4-nitro-phenyl)-ethylamino]-methyl}-phenolIC503900.0 [1]
4-(Dimethylamino)-2-methoxy-6-({[2-(4-nitrophenyl)ethyl]amino}methyl)phenolIC504000.0 [1]
2-(4-(7-(4-Methoxybenzoyl)cyclopenta[d][1,2]oxazin-4-yl)phenoxy)acetic acidIC5061700.0 [1]
2,5-Dihydroxy-3-(7-phenyl-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dioneIC5027000.0 [1]
2,5-Dihydroxy-3-[7-[(2-methylphenyl)methyl]-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dioneIC503500.0 [1]
3-(7-Benzyl-1H-indol-3-yl)-2,5-dihydroxycyclohexa-2,5-diene-1,4-dioneIC5015000.0 [1]
3-(6-Chloro-1h-indol-3-yl)-2,5-dihydroxycyclohexa-2,5-diene-1,4-dioneIC5040000.0 [1]
4-[N-[[3-(Dimethylamino)phenyl]methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(3-hydroxyphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC50100000.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(2-methylphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC50100000.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(4-methylphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC5056700.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(3-methoxyphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC50100000.0 [1]
4-[N-[(3-Chlorophenyl)methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(4-hydroxyphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC5044100.0 [1]
4-(N-Benzyl-C-pentadecylcarbonimidoyl)-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(2-hydroxyphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC50100000.0 [1]
4-[N-[(4-Chlorophenyl)methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
4-[N-[(4-Fluorophenyl)methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(4-methoxyphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC50100000.0 [1]
4-[N-[[4-(Dimethylamino)phenyl]methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
4-[N-[(2-Chlorophenyl)methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
4-[N-[(2-Fluorophenyl)methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC5047100.0 [1]
3-Hydroxy-2-(hydroxymethyl)-4-[N-[(2-methoxyphenyl)methyl]-C-pentadecylcarbonimidoyl]-2H-furan-5-oneIC50100000.0 [1]
4-[N-[[2-(Dimethylamino)phenyl]methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC50100000.0 [1]
4-[N-[(3-Fluorophenyl)methyl]-C-pentadecylcarbonimidoyl]-3-hydroxy-2-(hydroxymethyl)-2H-furan-5-oneIC5078200.0 [1]
8-(Diethylamino)naphtho[1,2-c]chromene-1,4,5-trioneIC50300.0 [1]
8-Methoxynaphtho[1,2-c]chromene-1,4,5-trioneIC50980.0 [1]
8-Fluoro-6H-benzo[i]phenanthridine-1,4,5-trioneIC504460.0 [1]
9-Chloro-6H-benzo[i]phenanthridine-1,4,5-trioneIC505720.0 [1]
8-Fluoronaphtho[1,2-c]chromene-1,4,5-trioneIC50690.0 [1]
8-Hydroxynaphtho[1,2-c]chromene-1,4,5-trioneIC50800.0 [1]
6-Methylbenzo[i]phenanthridine-1,4,5-trioneIC5014900.0 [1]
8-Chloro-6H-benzo[i]phenanthridine-1,4,5-trioneIC505500.0 [1]
9-Fluoronaphtho[1,2-c]chromene-1,4,5-trioneIC50400.0 [1]
9-Chloronaphtho[1,2-c]chromene-1,4,5-trioneIC501440.0 [1]
12-Oxapentacyclo[12.8.0.02,11.05,10.015,20]docosa-1(14),2(11),3,5,7,9,15(20),17,21-nonaene-13,16,19-trioneIC50100.0 [1]
9-Fluoro-6H-benzo[i]phenanthridine-1,4,5-trioneIC504670.0 [1]
8-Methylnaphtho[1,2-c]chromene-1,4,5-trioneIC501000.0 [1]
8-Phenylmethoxynaphtho[1,2-c]chromene-1,4,5-trioneIC507120.0 [1]
6H-Benzo[i]phenanthridine-1,4,5-trioneIC503640.0 [1]
12-Azapentacyclo[12.8.0.02,11.05,10.015,20]docosa-1(14),2(11),3,5,7,9,15(20),17,21-nonaene-13,16,19-trioneIC504370.0 [1]
8-Chloronaphtho[1,2-c]chromene-1,4,5-trioneIC50770.0 [1]
4-(2-Carboxyethyl)-3-decylfuran-2,5-dioneIC5053900.0 [1]
3-(4-Nonyl-2,5-dioxofuran-3-yl)propanoic acidIC50100000.0 [1]
3-(2,5-Dioxo-4-pentadecylfuran-3-yl)propanoic acidIC508600.0 [1]
3-(2,5-Dioxo-4-tridecylfuran-3-yl)propanoic acidIC505700.0 [1]
3-(2,5-Dioxo-4-tetradecylfuran-3-yl)propanoic acidIC5012600.0 [1]
2-[4-[3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]phenoxy]propanedioic acidKi30000.0 [1]
3-(1H-Indole-3-yl)-2,5-dihydroxy-p-benzoquinoneIC5030000.0 [1]
2-Dimethylamino-6-methoxy-4-({methyl-[2-(4-nitro-phenyl)-ethyl]-amino}-methyl)-phenolIC5020700.0 [1]
4-[2-[4-(1,2,3-Thiadiazole-4-yl)phenyl]-4-thiazolyl]benzonitrileIC508800.0 [1]
(2S)-3-[(1R)-2-[(1S,2S,5S,8Ar)-1,2,5,8a-tetramethyl-5-(4-methylpent-4-enyl)-3,6,7,8-tetrahydro-2H-naphthalen-1-yl]-1-hydroxyethyl]-2-hydroxy-2H-furan-5-oneIC502000000.0 [1]
2-[[4-[(2S)-3-[4-(3-Hydroxy-2-methoxycarbonylphenoxy)butylamino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-oxopropyl]-N-oxaloanilino]methyl]butanoic acidKi30000.0 [1]
2-({Methyl-[2-(4-nitro-phenyl)-ethyl]-amino}-methyl)-phenolIC5080000.0 [1]
Dimethyl-[4-({methyl-[2-(4-nitro-phenyl)-ethyl]-amino}-methyl)-phenyl]-amineIC5080000.0 [1]
Items per page: 1 - 10 of 100
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References

This online tool may be cited as follows

MLA

"Quest Database™ Dual specificity phosphatase Cdc25C Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/dual-specificity-phosphatase-cdc25c-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ Dual specificity phosphatase Cdc25C Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dual-specificity-phosphatase-cdc25c-inhibitors-ic50-ki.
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