 | Clozapine | IC50 | 58.0 [1], 120.0 [2], 138.0 [3], 156.0 [4], 168.0 [5] |
| Clozapine | Ki | 28.4 [1] |
 | Haloperidol | IC50 | 1.3 [1], 5.0 [2], 6.0 [3], 6.5 [4] |
| Haloperidol | Ki | 2.3 [1] |
 | 3-((4-(4-Chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo[2,3-b]pyridine | Ki | 0.43 [1] |
 | Quinpirole | Ki | 1.8 [1], 53.0 [2] |
 | N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide | Ki | 170.0 [1], 340.0 [2], 800.0 [3], 3600.0 [4] |
 | Olanzapine | IC50 | 173.0 [1] |
| Olanzapine | Ki | 28.0 [1] |
 | Risperidone | Ki | 6.2 [1], 7.0 [2] |
 | Pramipexole | Ki | 8.1 [1], 130.0 [2] |
 | N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide | Ki | 93.0 [1], 320.0 [2], 890.0 [3], 5740.0 [4] |
 | Quetiapine | Ki | 1000.0 [1], 1600.0 [2], 2200.0 [3] |
 | 2-Naphthalenecarboxamide, N-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)- | Ki | 38.9 [1], 39.0 [2], 44.0 [3], 300.0 [4] |
 | 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole | Ki | 220.0 [1], 449.0 [2], 1100.0 [3], 1520.0 [4], 1520.7 [5] |
 | CID 11477180 | Ki | 375.0 [1], 550.0 [2] |
 | N-[4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide | Ki | 2.0 [1], 128.82 [2], 130.0 [3], 150.0 [4] |
 | 5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole | Ki | 2.5 [1], 3.5 [2] |
 | 4-[3-(4-Chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]-1-(4-fluorophenyl)butan-1-one | Ki | 5.3 [1], 11.75 [2], 12.0 [3] |
 | (4-Ethynyl-3-cyclohexenyl)dipropylamine | Ki | -0.69 [1], 22.0 [2], 38.0 [3], 170.0 [4], 380.0 [5] |
 | N,N-Dipropyl-4-(2-trimethylsilylethynyl)cyclohex-3-en-1-amine | Ki | -0.76 [1], 54.0 [2], 160.0 [3], 640.0 [4], 3800.0 [5] |
 | Spiperone | IC50 | 0.5 [1] |
| Spiperone | Ki | 0.33 [1], 0.45 [2], 1.4 [3] |
 | Ziprasidone | Ki | 32.0 [1], 39.0 [2], 50.12 [3] |
 | Loxapine | IC50 | 14.0 [1] |
| Loxapine | Ki | 4.9 [1], 9.0 [2] |
 | N-[[4-(2-Cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide | Ki | 8.7 [1], 8.71 [2], 9.0 [3], 16.98 [4] |
 | 1-[4-(4-Chlorobenzyl)piperazinoacetyl]indoline | IC50 | 1.6 [1] |
| 1-[4-(4-Chlorobenzyl)piperazinoacetyl]indoline | Ki | 1.6 [1] |
 | N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide | Ki | 15.0 [1], 15.14 [2], 24.0 [3], 305.0 [4] |
 | (2R)-1-[4-(4-Methylbenzyl)piperazinoacetyl]-2-methylindoline | IC50 | 2.0 [1] |
| (2R)-1-[4-(4-Methylbenzyl)piperazinoacetyl]-2-methylindoline | Ki | 2.0 [1] |
 | (S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde | Ki | 32.0 [1], 2500.0 [2] |
 | Chlorpromazine | Ki | 25.12 [1], 30.0 [2], 479.0 [3] |
 | (1S,2R)-5-Methoxy-1-methyl-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine | Ki | 48.0 [1] |
 | N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]-9H-fluorene-2-carboxamide | Ki | 3670.0 [1], 5000.0 [2] |
 | N-(2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide | IC50 | 0.06 [1] |
| N-(2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide | Ki | 0.04 [1] |
 | CID 11301655 | IC50 | 5.0 [1] |
| CID 11301655 | Ki | 1.5 [1] |
 | N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide | Ki | 30.0 [1], 30.2 [2] |
 | US8748608, 34 Enantiomer A | Ki | 2600.0 [1], 4900.0 [2] |
 | 4-[4-(4-Chlorophenyl)piperazin-1-yl]-1-(4-fluorophenyl)butan-1-one | Ki | 7.6 [1], 17.0 [2], 17.5 [3] |
 | 4-(3-(4-Chlorophenyl)-3-hydroxypyrrolidin-1-yl)-1-(4-fluorophenyl)butan-1-one | Ki | 3.6 [1], 11.0 [2], 245.0 [3] |
 | N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)but-2-enyl)-9H-fluorene-2-carboxamide | Ki | 1020.0 [1] |
 | 1-Phenyl-4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazine | Ki | 1.0 [1] |
 | N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]-9-oxofluorene-4-carboxamide | Ki | 1116.0 [1], 1850.0 [2] |
 | N-[2-[4-(2-Methoxyphenyl)piperazin-1-yl]ethyl]pyrazolo[1,5-a]pyridine-3-carboxamide | Ki | 0.67 [1], 0.68 [2] |
 | N,N-Dimethyl-1-(3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl)methanamine | IC50 | 131.83 [1] |
 | 3-(4-Benzyl-piperazin-1-yl)-phenol | Ki | 400.0 [1] |
 | 4-[5-(4-Chloro-phenyl)-1H-pyrazol-3-yl]-1-phenethyl-piperidine | Ki | 5.5 [1] |
 | N-[3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide | Ki | 14.0 [1], 56.0 [2] |
 | N-[(E)-4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]but-2-enyl]-1-benzofuran-2-carboxamide | Ki | 1070.0 [1] |
 | 4-[5-(4-Chlorophenyl)-1H-pyrazol-3-yl]-1-[(4-chlorophenyl)methyl]piperidine | Ki | 61.0 [1] |
 | N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 32.0 [1], 32.36 [2], 107.15 [3] |
 | N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-4-methyl-benzamide | Ki | 1.2 [1], 6.46 [2], 6.5 [3] |
 | N-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide | Ki | 6.7 [1], 6.76 [2], 12.88 [3] |
 | 3-Methoxy-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)benzamide | IC50 | 1.0 [1] |
| 3-Methoxy-N-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)benzamide | Ki | 1.1 [1], 1.3 [2] |
 | 1-(2-Methoxy-phenyl)-4-(1-phenyl-1H-pyrrol-3-ylmethyl)-piperazine | Ki | 0.7 [1], 1.3 [2] |
 | 4-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 3.47 [1], 14.0 [2], 14.13 [3] |
 | N-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-4-methyl-benzamide | Ki | 3.39 [1], 7.7 [2], 7.76 [3] |
 | N-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 21.88 [1], 22.0 [2], 30.9 [3] |
 | N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-4-methyl-benzamide | Ki | 12.0 [1], 12.02 [2], 218.78 [3] |
 | 3-Chloro-N-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 15.0 [1], 15.14 [2] |
 | N-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide | Ki | 15.85 [1], 26.92 [2], 27.0 [3] |
 | 4-Chloro-N-[4-(2-chloro-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 5.25 [1], 5.3 [2], 8.32 [3] |
 | 4-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 3.89 [1], 5.5 [2] |
 | Dipropyl-(S)-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-5-yl-amine | Ki | 58.0 [1], 380.0 [2], 1700.0 [3] |
 | 1-[4-(4-Methylbenzyl)piperazinoacetyl]-2-methylindoline | IC50 | 3.0 [1] |
| 1-[4-(4-Methylbenzyl)piperazinoacetyl]-2-methylindoline | Ki | 3.0 [1], 7.0 [2] |
 | N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 23.99 [1], 26.92 [2], 27.0 [3] |
 | 3-Chloro-N-[4-(2-cyano-phenyl)-piperazin-1-ylmethyl]-benzamide | Ki | 5.25 [1], 33.88 [2], 34.0 [3] |
 | 1-Phenyl-4-((R)-2-phenyl-4,5-dihydro-1H-imidazol-4-ylmethyl)-piperazine; hydrochloride | Ki | 0.95 [1], 51.0 [2], 72.0 [3] |
 | Mianserin | IC50 | 3311.31 [1] |
 | Sertindole | Ki | 11.0 [1], 21.0 [2] |
 | Remoxipride | IC50 | 3872.0 [1] |
| Remoxipride | Ki | 3872.0 [1] |
 | Zotepine | Ki | 39.0 [1] |
 | GR-127935 | Ki | 10000.0 [1] |
 | Levosulpiride | Ki | 2100.0 [1] |
 | Ecopipam | Ki | 5515.0 [1], 5520.0 [2] |
 | Cariprazine | Ki | 110.0 [1] |
 | Fananserin | Ki | 2.9 [1] |
 | 5-Methoxy-1-methyl-2-(n-propylamino)tetralin | Ki | 117.0 [1] |
 | 7-Methyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine | Ki | 108.0 [1] |
 | Sonepiprazole | Ki | 3.6 [1], 6.8 [2] |
 | 2-[4-[(2-Phenyl-1H-imidazol-5-yl)methyl]piperazin-1-yl]pyrimidine | Ki | 3.6 [1], 3.8 [2] |
 | Tppcmp | Ki | 90.9 [1] |
 | 2-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine | IC50 | 110.0 [1] |
| 2-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine | Ki | 16.0 [1] |
 | 1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-phenylpiperazine | Ki | 170.0 [1], 180.0 [2] |
 | L-745,870 Hydrochloride | IC50 | 5.0 [1] |
| L-745,870 Hydrochloride | Ki | 0.43 [1] |
 | (R)-N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-3-hydroxybutyl)-1H-indole-2-carboxamide | Ki | 3430.0 [1], 4000.0 [2] |
 | N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide | Ki | 800.0 [1], 1698.24 [2] |
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