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Dopamine beta-hydroxylase Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
1-(4-Hydroxybenzyl)imidazole-2-thiolIC502570.4 [1]
1-Benzyl-1H-imidazole-2-thiolIC5033113.11 [1]
1-(3,5-Difluorobenzyl)-2-mercaptoimidazoleIC501202.26 [1]
3-[(3,5-Difluoro-4-hydroxyphenyl)methyl]-1H-imidazole-2-thioneIC5074.13 [1]
1-(4-Methoxybenzyl)-1H-imidazole-2-thiolIC50204173.79 [1]
1-(4-Fluorobenzyl)-1H-imidazole-2-thiolIC5046773.51 [1]
1-(3-Fluorobenzyl)-4-imidazoline-2-thioneIC505623.41 [1]
1-(4-Methylbenzyl)-1H-imidazole-2-thiolIC50147910.84 [1]
1-(4-Nitrobenzyl)-1H-imidazole-2(3H)-thioneIC5052480.75 [1]
1-(2,6-Dimethylbenzyl)-1H-imidazole-2(3H)-thioneIC501000000.0 [1]
1-(3-Bromo-4-methoxybenzyl)-2-mercaptoimidazoleIC5083176.38 [1]
1-(3,5-Difluoro-4-methoxybenzyl)-2-mercaptoimidazoleIC5036307.81 [1]
2H-Imidazole-2-thione, 1,3-dihydro-1-[[4-(trifluoromethyl)phenyl]methyl]-IC50199526.23 [1]
1-(3-Fluoro-4-methoxybenzyl)-1H-imidazole-2(3H)-thioneIC5074131.02 [1]
1-(4-Hydroxy-3-nitrobenzyl)imidazole-2-thioneIC5030902.95 [1]
1-(3-Trifluoromethyl-4-hydroxybenzyl)-2-mercaptoimidazoleIC50120226.44 [1]
1-(3,5-Dichlorobenzyl)-1H-imidazole-2(3H)-thioneIC502398.83 [1]
1-(2,6-Dichlorobenzyl)-1H-imidazole-2(3H)-thioneIC50707945.78 [1]
1-(2-Chlorobenzyl)-1H-imidazole-2-thiolIC50354813.39 [1]
1-(2,5-Dichlorobenzyl)-1H-imidazole-2(3H)-thioneIC5097723.72 [1]
1-(4-Chlorobenzyl)-1H-imidazole-2-thiolIC5095499.26 [1]
1-(2,3-Dichlorobenzyl)-1H-imidazole-2(3H)-thioneIC5052480.75 [1]
1-(3,4-Dichlorobenzyl)-1H-imidazole-2(3H)-thioneIC5028183.83 [1]
1-(2,4-Dichlorobenzyl)-1H-imidazole-2(3H)-thioneIC5016982.44 [1]
1-(3-Chlorobenzyl)-1H-imidazole-2(3H)-thioneIC5012022.64 [1]
1-(3,5-Dichloro-4-methoxybenzyl)-1H-imidazole-2(3H)-thioneIC5046773.51 [1]
1-(2,6-Dichloro-4-hydroxybenzyl)-2-mercaptoimidazoleIC5075857.76 [1]
1-(2,4,6-Trichlorobenzyl)-1H-imidazole-2(3H)-thioneIC50102329.3 [1]
2H-Imidazole-2-thione, 1,3-dihydro-1-[(4-methoxy-3-nitrophenyl)methyl]-IC50354813.39 [1]
1-(3-Trifluoromethyl-4-methoxybenzyl)-1H-imidazole-2(3H)-thioneIC50173780.08 [1]
1-(2,6-Dichloro-4-methoxybenzyl)-1H-imidazole-2(3H)-thioneIC50154881.66 [1]
1-(3-Fluoro-4-hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC501513.56 [1]
1-(2-Methoxybenzyl)-1H-imidazole-2-thiolIC5074131.02 [1]
1-(3,4-Dimethoxybenzyl)-1H-imidazole-2(3H)-thioneIC50338844.16 [1]
1-(2-Methylbenzyl)-1H-imidazole-2(3H)-thioneIC50338844.16 [1]
1-(2,6-Dimethoxybenzyl)-1H-imidazole-2(3H)-thioneIC50501187.23 [1]
1-(3-Hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC50147910.84 [1]
1-(3-Bromo-4-hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC5012022.64 [1]
1-(3-Methyl-4-hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC5048977.88 [1]
1-(2,3,5,6-Tetrafluoro-4-hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC5061659.5 [1]
1-(3,5-Dichloro-4-hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC50676.08 [1]
1-(3-Methoxybenzyl)-1H-imidazole-2(3H)-thioneIC50158489.32 [1]
1-(3-Chloro-4-hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC501995.26 [1]
1-(3,4-Dihydroxybenzyl)-1H-imidazole-2(3H)-thioneIC502187.76 [1]
1-(2-Hydroxybenzyl)-1H-imidazole-2(3H)-thioneIC50575439.94 [1]
1-(3-Methyl-4-methoxybenzyl)-1H-imidazole-2(3H)-thioneIC5069183.1 [1]
1-(4-Bromobenzyl)-1H-imidazole-2(3H)-thioneIC50114815.36 [1]
TropoloneIC502000.0 [1]
1-Propanone, 1-(3,4-dihydroxyphenyl)-2-methyl-IC5050000.0 [1]
3-HydroxytropoloneIC502000.0 [1]
3,7-DihydroxytropoloneIC503000.0 [1]
(E)-3-(3,4-Dihydroxy-5-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneIC5050000.0 [1]
(E)-3-(3,4-Dihydroxy-5-nitrophenyl)-1-phenylprop-2-en-1-oneIC5050000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ Dopamine beta-hydroxylase Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/dopamine-beta-hydroxylase-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ Dopamine beta-hydroxylase Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dopamine-beta-hydroxylase-inhibitors-ic50-ki.
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