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DNA topoisomerase II beta Inhibitors (IC50, Ki)

Structure
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Compound Name
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Standard Type
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Standard Values (in nM)
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▼
DoxorubicinIC503500.0 [1]
EtoposideIC5069.8 [1], 790.0 [2]
AmsacrineIC502760.0 [1]
[2,4-Dibromo-6-[(E)-3-(2-carbamothioylhydrazinyl)-3-oxo-2-[(3,4,5-trimethoxybenzoyl)amino]prop-1-enyl]phenyl] acetateIC5081.42 [1]
[2,4-Dibromo-6-[(Z)-[6-oxo-2-phenyl-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazin-5-ylidene]methyl]phenyl] acetateIC5012.6 [1]
[2,4-Dibromo-6-[(Z)-[1-methyl-8-oxo-3-sulfanylidene-5-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[1,2-a][1,2,4]triazin-7-ylidene]methyl]phenyl] acetateIC50110.45 [1]
[2,4-Dibromo-6-[(Z)-[6-oxo-2-(5-phenyl-1,3-thiazol-2-yl)-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazin-5-ylidene]methyl]phenyl] acetateIC506.85 [1]
[2,4-Dibromo-6-[(Z)-[2-carbamothioyl-6-oxo-3-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazin-5-ylidene]methyl]phenyl] acetateIC5031.68 [1]
1-Cyclopropyl-6-fluoro-7-[4-[2-[(2E)-2-[(2-hydroxyphenyl)methylidene]hydrazinyl]-2-oxoethyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acidIC50580.0 [1]
1-Cyclopropyl-6-fluoro-7-[4-[2-[(2E)-2-(1H-indol-2-ylmethylidene)hydrazinyl]-2-oxoethyl]piperazin-1-yl]-4-oxoquinoline-3-carboxylic acidIC50860.0 [1]
1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[4-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-ylamino)phenyl]ureaIC509290.0 [1]
Ethyl 7-[4-[4-[(5S)-5-(acetamidomethyl)-2-oxo-1,3-oxazolidin-3-yl]-2-fluorobenzoyl]piperazin-1-yl]-1-ethyl-6-fluoro-4-oxoquinoline-3-carboxylateIC5012500.0 [1]
Items per page: 1 - 10 of 12
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References

This online tool may be cited as follows

MLA

"Quest Database™ DNA topoisomerase II beta Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 22 Dec. 2024, https://www.aatbio.com/data-sets/dna-topoisomerase-ii-beta-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024, December 22). Quest Database™ DNA topoisomerase II beta Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dna-topoisomerase-ii-beta-inhibitors-ic50-ki.
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