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DNA polymerase lambda Inhibitors (IC50, Ki)

Structure
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▼
Compound Name
▲
▼
Standard Type
▲
▼
Standard Values (in nM)
▲
▼
AphidicolinIC50200000.0 [1]
2',3'-Dideoxythymidine triphosphateIC5028700.0 [1]
MelleinIC50316000.0 [1]
PecilocinIC50200000.0 [1]
(1R,3E,5S,6S,7R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-6-methyl-1,5,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)bicyclo[3.3.1]nonane-2,4,9-trioneIC505400.0 [1]
(1R,3E,5S,6S,7R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-7-[(2E)-3,7-dimethylocta-2,6-dienyl]-6-methyl-1,5-bis(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)bicyclo[3.3.1]nonane-2,4,9-trioneIC505200.0 [1]
[(7S,8S,8As)-7-hydroxy-7-methyl-6-oxo-3-[(E)-prop-1-enyl]-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoateIC50200000.0 [1]
3,5-Dimethyl-8-methoxy-3,4-dihydroisocoumarinIC5049000.0 [1]
Pinophilin BIC50200000.0 [1]
Hymenoic acidIC50100000.0 [1]
NodulisporoneIC5082000.0 [1]
NodulisporolIC50168000.0 [1]
(9Z)-9-Octadecenoic acid 5,8-dihydro-5,8-dioxonaphthalene-1-yl esterIC5010200.0 [1]
Dodecanoic acid 5,8-dihydro-5,8-dioxonaphthalene-1-yl esterIC507000.0 [1]
Pinophilin AIC50200000.0 [1]
1-[(2Z,4E,6E,8R)-8-Hydroxy-6-methyldodeca-2,4,6-trienoyl]pyrrolidin-2-oneIC50200000.0 [1]
(1R,3E,5S,6S,7R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-7-[(2E,5E)-7-hydroxy-3,7-dimethylocta-2,5-dienyl]-6-methyl-1,5-bis(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)bicyclo[3.3.1]nonane-2,4,9-trioneIC505600.0 [1]
(6E)-6-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-8-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,2-dimethyl-8-(3-methylbut-2-enyl)chromene-5,7-dioneIC506200.0 [1]
(1R,3Z,6R,9S,10R,13R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-13-[(2E)-3,7-dimethylocta-2,6-dienyl]-6-(2-hydroxypropan-2-yl)-9-methyl-1,10-bis(3-methylbut-2-enyl)-5-oxatricyclo[7.2.2.04,10]tridecane-2,11-dioneIC506900.0 [1]
(1R,3Z,6R,9S,10R,13R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-6-(2-hydroxypropan-2-yl)-9-methyl-1,10,13-tris(3-methylbut-2-enyl)-5-oxatricyclo[7.2.2.04,10]tridecane-2,11-dioneIC507400.0 [1]
(1R,3E,5S,6S,7R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-7-[(2E,6S)-6-hydroxy-3,7-dimethylocta-2,7-dienyl]-6-methyl-1,5-bis(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)bicyclo[3.3.1]nonane-2,4,9-trioneIC505800.0 [1]
(1R,3E,5S,6S,7S)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-7-(2-hydroxy-3-methylbut-3-enyl)-6-methyl-1,5-bis(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)bicyclo[3.3.1]nonane-2,4,9-trioneIC508800.0 [1]
(1R,3E,5S,6S,7R)-3-[(3,4-Dihydroxyphenyl)-hydroxymethylidene]-7-[(2E,6R)-6-hydroxy-3,7-dimethylocta-2,7-dienyl]-6-methyl-1,5-bis(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)bicyclo[3.3.1]nonane-2,4,9-trioneIC505000.0 [1]
5-Hydroxy-3-hydroxymethyl-2-methyl-7-methoxychromoneIC50454000.0 [1]
(1R,3E,5S,6S,7R)-3-[Hydroxy-(3-hydroxyphenyl)methylidene]-6-methyl-1,5,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)bicyclo[3.3.1]nonane-2,4,9-trioneIC505700.0 [1]
5-Formyl-8-hydroxy-3-methyl-3,4-dihydroisocoumarinIC50275000.0 [1]
8-Methoxy-3-methylisochroman-1-oneIC50180000.0 [1]
Tert-butyl N-[(2S)-3-(4-hydroxyphenyl)-1-[[(2S,3S)-3-methyl-1-(naphthalen-1-ylamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]carbamateIC50200000.0 [1]
(4E,6E)-6-Methyl-1-(2-oxopyrrolidin-1-yl)dodeca-4,6-diene-1,8-dioneIC50200000.0 [1]
1-[(4E,6E)-6-Methyl-7-(oxan-2-yl)hepta-4,6-dienoyl]pyrrolidin-2-oneIC50200000.0 [1]
Items per page: 1 - 10 of 30
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References

This online tool may be cited as follows

MLA

"Quest Database™ DNA polymerase lambda Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 21 Feb. 2025, https://www.aatbio.com/data-sets/dna-polymerase-lambda-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2025, February 21). Quest Database™ DNA polymerase lambda Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dna-polymerase-lambda-inhibitors-ic50-ki.
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