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DNA polymerase gamma subunit 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
AphidicolinIC50100000.0 [1]
psi-7409IC501000000.0 [1]
5-Methyluridine 5'-(tetrahydrogen triphosphate)IC5080000.0 [1]
N-Methylpyrimidone, 17IC5010000.0 [1]
2-[2-(Dimethylamino)propan-2-yl]-N-[(4-fluorophenyl)methyl]-5-hydroxy-6-oxo-1H-pyrimidine-4-carboxamideIC5010000.0 [1]
3-(4-Hydroxybutyl)-6-(3-ethyl-4-methylanilino)uracilKi1008000.0 [1]
2-[4-[[2-(4-Chlorophenyl)-5-(2-oxopyrrolidin-1-yl)phenyl]methoxy]-2-fluorophenyl]-1-cyclohexylbenzimidazole-5-carboxylic acidIC5010000.0 [1]
5-Acetyl-6-(2,4-dichlorophenyl)-9,9-dimethyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-oneIC50100000.0 [1]
N-(2-Diphosphorylphosphonylmethoxyethyl)guanineIC5059400.0 [1]
[[(2S,3R,5S)-5-(4-Amino-5-methyl-2-oxopyrimidin-1-yl)-3-fluorooxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC5050000.0 [1]
[[(2R,3R,4R,5S)-5-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-4-methyloxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC50100000.0 [1]
Kasanosin AIC5035000.0 [1]
Kasanosin BIC5072900.0 [1]
5-Acetyl-6-(4-methoxy-3-phenylmethoxyphenyl)-9,9-dimethyl-6,8,10,11-tetrahydrobenzo[b][1,4]benzodiazepin-7-oneIC50100000.0 [1]
[[(2S,3R,5S)-3-Fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC50100000.0 [1]
[[(2S,3R,5S)-5-(2,4-Dioxopyrimidin-1-yl)-3-fluorooxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC50100000.0 [1]
[[(2S,3R,5S)-5-(4-Amino-2-oxopyrimidin-1-yl)-3-fluorooxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphateIC5050000.0 [1]
1-Cyclopropyl-7-[4-[4-[6-(3-ethyl-4-methylanilino)-2,4-dioxo-1H-pyrimidin-3-yl]butyl]-3-methylpiperazin-1-yl]-6,8-difluoro-4-oxoquinoline-3-carboxylic acidKi684000.0 [1]
[[(R)-[(2S,5R)-5-(4-Amino-2-oxopyrimidin-1-yl)oxolan-2-yl]-fluoromethoxy]-hydroxyphosphoryl] phosphono hydrogen phosphateIC5085000.0 [1]
2-[2-Amino-6-(cyclopropylamino)purin-9-yl]ethoxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acidIC50150000.0 [1]
Tert-butyl N-[(2S)-3-(4-hydroxyphenyl)-1-[[(2S,3S)-3-methyl-1-(naphthalen-1-ylamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]carbamateIC50200000.0 [1]
(3S,6Z,8E,11S)-3-[(1E,3E,5E)-7-(Dimethylamino)-2,5-dimethylhepta-1,3,5-trienyl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dioneIC503000.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ DNA polymerase gamma subunit 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.20 Nov2024https://www.aatbio.com/data-sets/dna-polymerase-gamma-subunit-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 20). Quest Database™ DNA polymerase gamma subunit 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dna-polymerase-gamma-subunit-1-inhibitors-ic50-ki.
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