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DNA ligase 1 Inhibitors (IC50, Ki)

Structure
Compound Name
Standard Type
Standard Values (in nM)
2,3-Dioxoindoline-7-carboxylic acidIC504000.0 [1]
2,3-Dioxoindoline-7-carboxylic acidKi4000.0 [1]
4-{[(4-Carboxy-5-methyl(2-furyl))methylthio]methyl}-5-methylfuran-2-carboxylic acidIC50600.0 [1]
N-{2-[4-(Aminosulfonyl)phenyl]ethyl}-3-[(4-bromophenyl)sulfonyl]propanamideIC508000.0 [1]
2-(Butylsulfanyl)adenosineIC50200000.0 [1]
[(7-Chloro-4-nitro-2,1,3-benzoxadiazol-5-yl)thio]-acetic acidIC5013000.0 [1]
5-Methylsulfanylthiophene-2-carboxylic acidIC5010000.0 [1]
4-Chloro-5-[(2Z)-2-(4-hydroxy-3-nitrobenzylidene)hydrazinyl]pyridazin-3(2H)-oneIC5012000.0 [1]
DNA Ligase InhibitorIC508000.0 [1]
2,4'-DihydroxybenzophenoneIC5025000.0 [1]
3-Amino-2-(benzylideneamino)-5-mercaptophenolIC504000.0 [1]
7-(4-Methoxyphenyl)-2,4-pteridinediolIC5025000.0 [1]
4-Amino-2-cyclopentyloxy-6-[(1S,2S)-2-hydroxycyclohexyl]oxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-2-[(1R,2S)-2-methylcyclohexyl]oxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-2-propan-2-yloxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-2-cyclopentyloxy-6-(2-fluorophenoxy)pyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-2-cyclopentyloxy-6-[(1S,2R)-2-(hydroxymethyl)cyclohexyl]oxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-2-(Cyclopentyloxy)pyrimidine-5-CarboxamideIC5055000.0 [1]
4-Amino-2-(2-fluoroethoxy)pyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-2-cyclopentyloxy-6-[(3S)-3-[(3,5-dimethoxyanilino)methyl]cyclohexyl]oxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-6-cyclohexyloxy-2-propan-2-yloxypyrimidine-5-carboxamideIC5055000.0 [1]
3-[3-(6-Amino-5-carbamoyl-2-cyclopentyloxypyrimidin-4-yl)oxyphenyl]propanoic acidIC5055000.0 [1]
4-Amino-2-cyclohexyloxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-6-[(1S,2S)-2-hydroxycyclopentyl]oxy-2-propan-2-yloxypyrimidine-5-carboxamideIC5055000.0 [1]
2-(4-Amino-5-carbamoylpyrimidin-2-yl)oxypropanoic acidIC5055000.0 [1]
4-Amino-2-cyclopentyloxy-6-[(1S,2R)-2-hydroxycyclopentyl]oxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-2-cyclopentyloxy-6-(2-fluorocyclohexyl)oxypyrimidine-5-carboxamideIC5055000.0 [1]
4-Amino-6-[(1S,2S)-2-hydroxycyclopentyl]oxy-2-(4-methylcyclohexyl)oxypyrimidine-5-carboxamideIC5055000.0 [1]
1,6-Diphenyldispiro[2.1.2.3]decan-4-oneIC50130000.0 [1]
1,6-Bis(4-fluorophenyl)dispiro[2.1.2.3]decan-4-oneIC5045400.0 [1]
2,6-Bis(4-bromophenyl)dispiro[2.1.25.33]decan-4-oneIC5058600.0 [1]
2,6-Bis(4-chlorophenyl)dispiro[2.1.25.33]decan-4-oneIC5018500.0 [1]
N-Hydroxy-2-prop-2-enoxybenzamideIC5059300.0 [1]
N-Hydroxy-2-[2-hydroxy-3-(4-phenyltriazol-1-yl)propoxy]benzamideIC5041800.0 [1]



References

This online tool may be cited as follows

MLA

"Quest Database™ DNA ligase 1 Inhibitors (IC50, Ki)." AAT Bioquest, Inc.23 Nov2024https://www.aatbio.com/data-sets/dna-ligase-1-inhibitors-ic50-ki.

APA

AAT Bioquest, Inc. (2024November 23). Quest Database™ DNA ligase 1 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dna-ligase-1-inhibitors-ic50-ki.
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