DNA excision repair protein ERCC-5 Inhibitors (IC50, Ki)

Structure ▲ ▼	Compound Name ▲ ▼	Standard Type ▲ ▼	Standard Values (in nM) ▲ ▼
	2,4-Dioxo-4-phenylbutanoic acid	IC50	75400.0 [1]
	3-Hydroxyquinazoline-2,4(1H,3H)-dione	IC50	0.16 [1]
	3-Hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dione	IC50	0.1 [1]
	3-Hydroxy-6-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-dione	IC50	0.2 [1]
	3-Hydroxy-5-methylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione	IC50	0.14 [1]
	5,6-Dibutyl-3-hydroxy-1H-thieno[2,3-d]pyrimidine-2,4-dione	IC50	0.16 [1]
	3-Hydroxy-7-phenyl-1H-thieno[3,2-d]pyrimidine-2,4-dione	IC50	0.03 [1]
	1-((2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-3-hydroxythieno[3,2-d]pyrimidine-2,4(1H,3H)-dione	IC50	0.29 [1]
	4-(2-Fluorophenyl)-2,4-dioxobutyric acid	IC50	78500.0 [1]
	3-Hydroxy-7-(4-methylphenyl)furo[3,2-d]pyrimidine-2,4(1H,3H)-dione	IC50	0.13 [1]
	1-Benzyl-3-hydroxythieno[2,3-d]pyrimidine-2,4(1H,3H)-dione	IC50	2.0 [1]
	2,4-Dioxo-4-(4-phenoxyphenyl)butanoic acid	IC50	1870.0 [1]
	4-(Furan-2-yl)-2,4-dioxobutanoic acid	IC50	41000.0 [1]
	(1,1'-BIPHENYL)-4-BUTANOIC ACID, alpha,gamma-DIOXO-	IC50	1600.0 [1]
	4-(2-Chloro-phenyl)-2,4-dioxo-butyric acid	IC50	38100.0 [1]
	3-Hydroxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-5-methyl-1H-thieno[2,3-d]pyrimidine-2,4-dione	IC50	3.04 [1]
	3-Hydroxy-1H-[1]benzothiolo[3,2-d]pyrimidine-2,4-dione	IC50	0.06 [1]
	1-(3-Bromo-benzyl)-3-hydroxy-1H-thieno[3,2-d]pyrimidine-2,4-dione	IC50	0.55 [1]
	3-Hydroxy-5-methyl-1-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione	IC50	3.99 [1]
	7-Biphenyl-4-yl-3-hydroxy-1H-furo[3,2-d]pyrimidine-2,4-dione	IC50	0.14 [1]
	3-Hydroxybenzofuro[3,2-d]pyrimidine-2,4(1H,3H)-dione	IC50	0.26 [1]
	CID 11608580	IC50	0.06 [1]
	N-[3-[3-[(3-Hydroxy-2,4-dioxothieno[3,2-d]pyrimidin-1-yl)methyl]phenyl]phenyl]acetamide	IC50	0.56 [1]
	7-Tert-Butyl-3-hydroxy-1H-thieno[3,2-d]pyrimidine-2,4-dione	IC50	0.26 [1]
	4-[3-[(3-Hydroxy-2,4-dioxothieno[3,2-d]pyrimidin-1-yl)methyl]phenyl]benzamide	IC50	0.23 [1]
	7-(Benzenesulfonyl)-3-hydroxy-1H-thieno[3,2-d]pyrimidine-2,4-dione	IC50	0.02 [1]
	3-Hydroxy-7-(3-methoxy-phenyl)-1H-furo[3,2-d]pyrimidine-2,4-dione	IC50	0.21 [1]
	2-Methylene-3-(4-phenoxybenzoyl)propionic acid	IC50	100000.0 [1]
	2,4-Dioxo-4-(thiophen-2-yl)butanoic acid	IC50	38700.0 [1]
	4-(2,4-Dichloro-phenyl)-2,4-dioxo-butyric acid	IC50	9850.0 [1]
	4-(4-Chlorophenyl)-2,4-dioxobutanoic acid	IC50	12700.0 [1]
	5-Chloro-3-hydroxyquinazoline-2,4(1H,3H)-dione	IC50	0.18 [1]
	4-[3-[(3-Hydroxy-7-methyl-2,4-dioxothieno[3,2-d]pyrimidin-1-yl)methyl]phenyl]benzamide	IC50	30.2 [1]
	3-Hydroxy-7-phenylfuro[3,2-d]pyrimidine-2,4(1H,3H)-dione	IC50	0.28 [1]
	3-Hydroxy-7-(4-methoxyphenyl)-1H-furo[3,2-d]pyrimidine-2,4-dione	IC50	0.23 [1]
	7-(4-Bromophenyl)-3-hydroxyfuro[3,2-d]pyrimidine-2,4(1H,3H)-dione	IC50	0.33 [1]
	3-Hydroxy-1-(4-methoxyphenyl)-5-methylthieno[2,3-d]pyrimidine-2,4-dione	IC50	8.45 [1]
	3-Hydroxy-1,5-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione	IC50	4.62 [1]
	2,4-Dioxo-4-[5-(4-trifluoromethoxy-phenyl)-thiophen-2-yl]-butyric acid	IC50	310.0 [1]
	2-Oxo-3-(5-phenyl-thiazol-2-yl)-propionic acid	IC50	31700.0 [1]
	1-(3-Oxo-1,2-oxazol-5-yl)-3-(4-phenoxyphenyl)propane-1,3-dione	IC50	100000.0 [1]
	1-[1-[(4-Methoxyphenyl)methyl]tetrazol-5-yl]-3-(4-phenylphenyl)propane-1,3-dione	IC50	52400.0 [1]
	2,4-Dioxo-4-(5-trifluoromethyl-thiophen-2-yl)-butyric acid	IC50	2320.0 [1]
	4-[5-(4-Chloro-3-fluorophenyl)thiophen-2-yl]-2,4-dioxobutanoic acid	IC50	900.0 [1]
	1-Biphenyl-4-yl-3-(1H-tetrazol-5-yl)-propane-1,3-dione	IC50	100000.0 [1]
	1-(4-Phenoxy-phenyl)-3-(1H-tetrazol-5-yl)-propane-1,3-dione	IC50	97000.0 [1]
	(8-Hydroxy-[1,6]naphthyridin-7-yl)-(4-phenoxy-phenyl)-methanone	IC50	100000.0 [1]
	4-[5-(2-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyric acid	IC50	1850.0 [1]
	4-[5-(4-Tert-Butyl-phenyl)-furan-2-yl]-2,4-dioxo-butyric acid	IC50	3130.0 [1]
	4-[5-(4-Chloro-phenyl)-furan-2-yl]-2,4-dioxo-butyric acid	IC50	980.0 [1]
	2,4-Dioxo-4-(5-phenyl-furan-2-yl)-butyric acid	IC50	1810.0 [1]
	4-[5-(4-Ethoxy-phenyl)-furan-2-yl]-2,4-dioxo-butyric acid	IC50	1400.0 [1]
	4-(2,6-Dichlorophenyl)-2,4-dioxobutanoic acid	IC50	100000.0 [1]
	4-[2-Chloro-5-(4-methoxyphenyl)phenyl]-2,4-dioxobutanoic acid	IC50	570.0 [1]
	4-(2,3-Dichloro-phenyl)-2,4-dioxo-butyric acid	IC50	22100.0 [1]
	4-(2,5-Dichloro-phenyl)-2,4-dioxo-butyric acid	IC50	7000.0 [1]
	4-[3-(4-Methoxyphenyl)phenyl]-2,4-dioxobutanoic acid	IC50	1590.0 [1]
	4-[2-Chloro-4-(4-chlorophenyl)phenyl]-2,4-dioxobutanoic acid	IC50	1770.0 [1]
	4-(4-Chloro-biphenyl-3-yl)-2,4-dioxo-butyric acid	IC50	1130.0 [1]
	2,4-Dioxo-4-(5-phenyl-2-thienyl)butanoic acid	IC50	1850.0 [1]
	4-(2-Methylphenyl)-2,4-dioxobutanoic acid	IC50	54500.0 [1]
	2,4-Dioxo-4-(3-phenylphenyl)butanoic acid	IC50	3240.0 [1]
	2,4-Dioxo-4-(3-phenoxyphenyl)butanoic acid	IC50	5440.0 [1]
	4-(3-Chlorophenyl)-2,4-dioxobutanoic acid	IC50	13100.0 [1]

Entire TableStructureCompound NameStandard TypeStandard Values (in nM)

Items per page: 510All1 - 10 of 64 ⟨⟩

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References

This online tool may be cited as follows

MLA	"Quest Database™ DNA excision repair protein ERCC-5 Inhibitors (IC50, Ki)." AAT Bioquest, Inc., 20 Feb. 2025, https://www.aatbio.com/data-sets/dna-excision-repair-protein-ercc-5-inhibitors-ic50-ki.
APA	AAT Bioquest, Inc. (2025, February 20). Quest Database™ DNA excision repair protein ERCC-5 Inhibitors (IC50, Ki). AAT Bioquest. https://www.aatbio.com/data-sets/dna-excision-repair-protein-ercc-5-inhibitors-ic50-ki.
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